☰

Daniel N. Bolon, Ph.D. - Publications

Affiliations: 
Biochemistry and Molecular Pharmacology University of Massachusetts Medical School, Worcester, MA, United States 
Area:
molecular evolution
Tree Info Similar researchers PubMed Report error

36/54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Flynn JM, Rossouw A, Cote-Hammarlof P, Fragata I, Mavor D, Hollins C, Bank C, Bolon DN. Comprehensive fitness maps of Hsp90 show widespread environmental dependence. Elife. 9. PMID 32129763 DOI: 10.7554/Elife.53810  0.375
2020 Bolon D. Lessons from Experimental Protein Fitness Landscapes Biophysical Journal. 118: 172a. DOI: 10.1016/J.Bpj.2019.11.1051  0.378
2018 Mavor D, Barlow KA, Asarnow D, Birman Y, Britain D, Chen W, Green EM, Kenner LR, Mensa B, Morinishi LS, Nelson CA, Poss EM, Suresh P, Tian R, Arhar T, ... ... Bolon DN, et al. Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance. Biology Open. 7. PMID 30037883 DOI: 10.1242/Bio.036103  0.442
2018 Canale AS, Cote-Hammarlof PA, Flynn JM, Bolon DN. Evolutionary mechanisms studied through protein fitness landscapes. Current Opinion in Structural Biology. 48: 141-148. PMID 29351890 DOI: 10.1016/J.Sbi.2018.01.001  0.408
2017 Ma L, Boucher JI, Paulsen J, Matuszewski S, Eide CA, Ou J, Eickelberg G, Press RD, Zhu LJ, Druker BJ, Branford S, Wolfe SA, Jensen JD, Schiffer CA, Green MR, ... Bolon DN, et al. CRISPR-Cas9-mediated saturated mutagenesis screen predicts clinical drug resistance with improved accuracy. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078326 DOI: 10.1073/Pnas.1708268114  0.698
2017 Ormond L, Liu P, Matuszewski S, Renzette N, Bank C, Zeldovich K, Bolon DN, Kowalik TF, Finberg RW, Jensen JD, Wang JP. The Combined Effect of Oseltamivir and Favipiravir on Influenza A Virus Evolution. Genome Biology and Evolution. 9: 1913-1924. PMID 28854600 DOI: 10.1093/Gbe/Evx138  0.402
2016 Prachanronarong KL, Özen A, Thayer KM, Yilmaz LS, Zeldovich KB, Bolon DN, Kowalik TF, Jensen JD, Finberg RW, Wang JP, Kurt-Yilmaz N, Schiffer CA. Molecular Basis for Differential Patterns of Drug Resistance in Influenza N1 and N2 Neuraminidase. Journal of Chemical Theory and Computation. 12: 6098-6108. PMID 27951676 DOI: 10.1021/Acs.Jctc.6B00703  0.339
2016 Duenas-Decamp M, Jiang L, Bolon D, Clapham PR. Saturation Mutagenesis of the HIV-1 Envelope CD4 Binding Loop Reveals Residues Controlling Distinct Trimer Conformations. Plos Pathogens. 12: e1005988. PMID 27820858 DOI: 10.1371/Journal.Ppat.1005988  0.309
2016 Mavor D, Barlow K, Thompson S, Barad BA, Bonny AR, Cario CL, Gaskins G, Liu Z, Deming L, Axen SD, Caceres E, Chen W, Cuesta A, Gate R, Green EM, ... ... Bolon DN, et al. Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting. Elife. 5. PMID 27111525 DOI: 10.7554/Elife.15802  0.434
2016 Mishra P, Flynn JM, Starr TN, Bolon DN. Systematic Mutant Analyses Elucidate General and Client-Specific Aspects of Hsp90 Function. Cell Reports. PMID 27068472 DOI: 10.1016/j.celrep.2016.03.046  0.33
2016 Boucher JI, Bolon DN, Tawfik DS. Quantifying and understanding the fitness effects of protein mutations: Laboratory versus nature. Protein Science : a Publication of the Protein Society. PMID 27010590 DOI: 10.1002/Pro.2928  0.726
2015 Jiang L, Liu P, Bank C, Renzette N, Prachanronarong K, Yilmaz LS, Caffrey DR, Zeldovich KB, Schiffer CA, Kowalik TF, Jensen JD, Finberg RW, Wang JP, Bolon DN. A balance between inhibitor binding and substrate processing confers influenza drug resistance. Journal of Molecular Biology. PMID 26656922 DOI: 10.1016/J.Jmb.2015.11.027  0.3
2015 Bank C, Hietpas RT, Jensen JD, Bolon DN. A systematic survey of an intragenic epistatic landscape. Molecular Biology and Evolution. 32: 229-38. PMID 25371431 DOI: 10.1093/Molbev/Msu301  0.374
2014 Boucher JI, Cote P, Flynn J, Jiang L, Laban A, Mishra P, Roscoe BP, Bolon DN. Viewing protein fitness landscapes through a next-gen lens. Genetics. 198: 461-71. PMID 25316787 DOI: 10.1534/Genetics.114.168351  0.728
2014 Foll M, Poh YP, Renzette N, Ferrer-Admetlla A, Bank C, Shim H, Malaspinas AS, Ewing G, Liu P, Wegmann D, Caffrey DR, Zeldovich KB, Bolon DN, Wang JP, Kowalik TF, et al. Influenza virus drug resistance: a time-sampled population genetics perspective. Plos Genetics. 10: e1004185. PMID 24586206 DOI: 10.1371/Journal.Pgen.1004185  0.371
2014 Bank C, Hietpas RT, Wong A, Bolon DN, Jensen JD. A Bayesian MCMC approach to assess the complete distribution of fitness effects of new mutations: Uncovering the potential for adaptive walks in challenging environments Genetics. 196: 841-852. PMID 24398421 DOI: 10.1534/Genetics.113.156190  0.426
2014 Renzette N, Caffrey DR, Zeldovich KB, Liu P, Gallagher GR, Aiello D, Porter AJ, Kurt-Jones EA, Bolon DN, Poh YP, Jensen JD, Schiffer CA, Kowalik TF, Finberg RW, Wang JP. Evolution of the influenza A virus genome during development of oseltamivir resistance in vitro. Journal of Virology. 88: 272-81. PMID 24155392 DOI: 10.1128/Jvi.01067-13  0.389
2014 Wagenaar TR, Ma L, Roscoe B, Park SM, Bolon DN, Green MR. Resistance to vemurafenib resulting from a novel mutation in the BRAFV600E kinase domain. Pigment Cell & Melanoma Research. 27: 124-33. PMID 24112705 DOI: 10.1111/Pcmr.12171  0.386
2013 Beebe K, Mollapour M, Scroggins B, Prodromou C, Xu W, Tokita M, Taldone T, Pullen L, Zierer BK, Lee MJ, Trepel J, Buchner J, Bolon D, Chiosis G, Neckers L. Posttranslational modification and conformational state of heat shock protein 90 differentially affect binding of chemically diverse small molecule inhibitors. Oncotarget. 4: 1065-74. PMID 23867252 DOI: 10.18632/Oncotarget.1099  0.382
2011 Wayne N, Mishra P, Bolon DN. Hsp90 and client protein maturation Methods in Molecular Biology. 787: 33-44. PMID 21898225 DOI: 10.1007/978-1-61779-295-3_3  0.324
2010 Wayne N, Lai YS, Pullen L, Bolon DN. Modular control of cross-oligomerization: Analysis of superstabilized Hsp90 homodimers in vivo Journal of Biological Chemistry. 285: 234-241. PMID 19906642 DOI: 10.1074/Jbc.M109.060129  0.346
2009 Munson M, Bolon DN. Watching proteins in motion. Genome Biology. 10: 316. PMID 19863776 DOI: 10.1186/Gb-2009-10-10-316  0.305
2009 Wayne N, Bolon D. Controlling oligomerization through protein engineering: in vivo analysis of Hsp90 Biophysical Journal. 96: 434a-435a. DOI: 10.1016/J.Bpj.2008.12.2226  0.387
2008 Haririnia A, Verma R, Purohit N, Twarog MZ, Deshaies RJ, Bolon D, Fushman D. Mutations in the hydrophobic core of ubiquitin differentially affect its recognition by receptor proteins. Journal of Molecular Biology. 375: 979-96. PMID 18054791 DOI: 10.1016/J.Jmb.2007.11.016  0.458
2007 Wayne N, Bolon DN. Dimerization of Hsp90 is required for in vivo function: Design and analysis of monomers and dimers Journal of Biological Chemistry. 282: 35386-35395. PMID 17908693 DOI: 10.1074/Jbc.M703844200  0.326
2007 McGinness KE, Bolon DN, Kaganovich M, Baker TA, Sauer RT. Altered tethering of the SspB adaptor to the ClpXP protease causes changes in substrate delivery. The Journal of Biological Chemistry. 282: 11465-73. PMID 17317664 DOI: 10.1074/Jbc.M610671200  0.534
2005 Bolon DN, Grant RA, Baker TA, Sauer RT. Specificity versus stability in computational protein design. Proceedings of the National Academy of Sciences of the United States of America. 102: 12724-9. PMID 16129838 DOI: 10.1073/Pnas.0506124102  0.542
2005 Hersch GL, Burton RE, Bolon DN, Baker TA, Sauer RT. Asymmetric interactions of ATP with the AAA+ ClpX6 unfoldase: allosteric control of a protein machine. Cell. 121: 1017-27. PMID 15989952 DOI: 10.1016/J.Cell.2005.05.024  0.525
2004 Bolon DN, Grant RA, Baker TA, Sauer RT. Nucleotide-dependent substrate handoff from the SspB adaptor to the AAA+ ClpXP protease. Molecular Cell. 16: 343-50. PMID 15525508 DOI: 10.1016/J.Molcel.2004.10.001  0.515
2004 Sauer RT, Bolon DN, Burton BM, Burton RE, Flynn JM, Grant RA, Hersch GL, Joshi SA, Kenniston JA, Levchenko I, Neher SB, Oakes ES, Siddiqui SM, Wah DA, Baker TA. Sculpting the proteome with AAA(+) proteases and disassembly machines. Cell. 119: 9-18. PMID 15454077 DOI: 10.1016/J.Cell.2004.09.020  0.523
2004 Bolon DN, Wah DA, Hersch GL, Baker TA, Sauer RT. Bivalent tethering of SspB to ClpXP is required for efficient substrate delivery: a protein-design study. Molecular Cell. 13: 443-9. PMID 14967151 DOI: 10.1016/S1097-2765(04)00027-9  0.54
2003 Wah DA, Levchenko I, Rieckhof GE, Bolon DN, Baker TA, Sauer RT. Flexible linkers leash the substrate binding domain of SspB to a peptide module that stabilizes delivery complexes with the AAA+ ClpXP protease. Molecular Cell. 12: 355-63. PMID 14536075 DOI: 10.1016/S1097-2765(03)00272-7  0.509
2003 Bolon DN, Marcus JS, Ross SA, Mayo SL. Prudent modeling of core polar residues in computational protein design. Journal of Molecular Biology. 329: 611-22. PMID 12767838 DOI: 10.1016/S0022-2836(03)00423-6  0.568
2002 Bolon DN, Voigt CA, Mayo SL. De novo design of biocatalysts. Current Opinion in Chemical Biology. 6: 125-9. PMID 12038994 DOI: 10.1016/S1367-5931(02)00303-4  0.66
2001 Bolon DN, Mayo SL. Enzyme-like proteins by computational design. Proceedings of the National Academy of Sciences of the United States of America. 98: 14274-9. PMID 11724958 DOI: 10.1073/Pnas.251555398  0.637
2001 Bolon DN, Mayo SL. Polar residues in the protein core of Escherichia coli thioredoxin are important for fold specificity. Biochemistry. 40: 10047-53. PMID 11513583 DOI: 10.1021/Bi010427Y  0.618
Low-probability matches (unlikely to be authored by this person)
2015 Flynn JM, Mishra P, Bolon DN. Mechanistic Asymmetry in Hsp90 Dimers. Journal of Molecular Biology. 427: 2904-11. PMID 25843003 DOI: 10.1016/j.jmb.2015.03.017  0.299
2011 Pullen L, Bolon DN. Enforced N-domain proximity stimulates Hsp90 ATPase activity and is compatible with function in vivo Journal of Biological Chemistry. 286: 11091-11098. PMID 21278257 DOI: 10.1074/Jbc.M111.223131  0.294
2010 Wayne N, Bolon DN. Charge-Rich Regions Modulate the Anti-Aggregation Activity of Hsp90 Journal of Molecular Biology. 401: 931-939. PMID 20615417 DOI: 10.1016/J.Jmb.2010.06.066  0.29
2015 Zeldovich KB, Liu P, Renzette N, Foll M, Pham ST, Venev SV, Gallagher GR, Bolon DN, Kurt-Jones EA, Jensen JD, Caffrey DR, Schiffer CA, Kowalik TF, Wang JP, Finberg RW. Positive Selection Drives Preferred Segment Combinations during Influenza Virus Reassortment. Molecular Biology and Evolution. 32: 1519-32. PMID 25713211 DOI: 10.1093/Molbev/Msv044  0.283
2016 Bank C, Renzette N, Liu P, Matuszewski S, Shim H, Foll M, Bolon DN, Zeldovich KB, Kowalik TF, Finberg RW, Wang JP, Jensen JD. An experimental evaluation of drug-induced mutational meltdown as an antiviral treatment strategy. Evolution; International Journal of Organic Evolution. PMID 27566611 DOI: 10.1111/Evo.13041  0.246
2012 Mittal S, Cai Y, Nalam MN, Bolon DN, Schiffer CA. Hydrophobic core flexibility modulates enzyme activity in HIV-1 protease. Journal of the American Chemical Society. 134: 4163-8. PMID 22295904 DOI: 10.1021/Ja2095766  0.238
2020 Flynn JM, Rossouw A, Cote-Hammarlof P, Fragata I, Mavor D, Hollins C, Bank C, Bolon DN. Author response: Comprehensive fitness maps of Hsp90 show widespread environmental dependence Elife. DOI: 10.7554/Elife.53810.Sa2  0.231
2016 Mavor D, Barlow K, Thompson S, Barad BA, Bonny AR, Cario CL, Gaskins G, Liu Z, Deming L, Axen SD, Caceres E, Chen W, Cuesta A, Gate RE, Green EM, ... ... Bolon DN, et al. Author response: Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting Elife. DOI: 10.7554/Elife.15802.023  0.224
2017 Ichikawa Y, Connelly CF, Appleboim A, Miller TC, Jacobi H, Abshiru NA, Chou H, Chen Y, Sharma U, Zheng Y, Thomas PM, Chen HV, Bajaj V, Müller CW, Kelleher NL, ... ... Bolon DN, et al. Author response: A synthetic biology approach to probing nucleosome symmetry Elife. DOI: 10.7554/Elife.28836.019  0.214
2017 Ichikawa Y, Connelly CF, Appleboim A, Miller TC, Jacobi H, Abshiru NA, Chou HJ, Chen Y, Sharma U, Zheng Y, Thomas PM, Chen HV, Bajaj V, Müeller CW, Kelleher NL, ... ... Bolon DN, et al. A synthetic biology approach to probing nucleosome symmetry. Elife. 6. PMID 28895528 DOI: 10.7554/Elife.28836  0.136
2017 Van Oosten-Hawle P, Bolon DN, LaPointe P. The diverse roles of Hsp90 and where to find them. Nature Structural & Molecular Biology. 24: 1-4. PMID 28054566 DOI: 10.1038/nsmb.3359  0.1
1992 Ambrosino DM, Bolon D, Collard H, Van Etten R, Kanchana MV, Finberg RW. Effect of Haemophilus influenzae polysaccharide outer membrane protein complex conjugate vaccine on macrophages Journal of Immunology. 149: 3978-3983. PMID 1460286  0.093
1996 Cardwell R, Bolon D. Strategic alliances and hospitals: a US perspective. Journal of Management in Medicine. 10: 40-46. PMID 10162756  0.018
2013 Anjum J, Bolon D. Retaining experienced hospital administrators: a neglected topic in healthcare. Hospital Topics. 91: 87-93. PMID 24255937  0.018
1994 Guinan EC, Molrine DC, Antin JH, Lee MC, Weinstein HJ, Sallan SE, Parsons SK, Wheeler C, Gross W, McGarigle C, Blanding P, Schiffman G, Finberg RW, Siber GR, Bolon D, et al. Polysaccharide conjugate vaccine responses in bone marrow transplant patients Transplantation. 57: 677-684. PMID 8140632 DOI: 10.1097/00007890-199403150-00009  0.017
2016 Bolon DN, Baker D, Tawfik DS. Editorial. Protein Science : a Publication of the Protein Society. PMID 27214768 DOI: 10.1002/Pro.2949  0.01
2004 Meyer D, Hamel-Lambert J, Tice C, Safran S, Bolon D, Rose-Grippa K. Recruiting and retaining mental health professionals to rural communities: An interdisciplinary course in appalachia Journal of Rural Health. 21: 86-91. PMID 15667015 DOI: 10.1111/j.1748-0361.2005.tb00067.x  0.01
2004 Lasic Z, Bolon D, Kesanakurthy S, Nikolsky E, Coplan N, Leon MB, Wolff SD. A saphenous vein graft aneurysm fistula causing pulmonary artery dissection Clinical Cardiology. 27: 450. PMID 15346840  0.01
Hide low-probability matches.