Csaba Pal - Publications

Affiliations: 
Biological Research Center Hungarian Academy of Sciences, Szeged 

73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Jangir PK, Ogunlana L, Szili P, Czikkely M, Shaw LP, Stevens EJ, Yang Y, Yang Q, Wang Y, Pál C, Walsh TR, MacLean CR. The evolution of colistin resistance increases bacterial resistance to host antimicrobial peptides and virulence. Elife. 12. PMID 37094804 DOI: 10.7554/eLife.84395  0.324
2023 Apjok G, Számel M, Christodoulou C, Seregi V, Vásárhelyi BM, Stirling T, Eszenyi B, Sári T, Vidovics F, Nagrand E, Kovács D, Szili P, Lantos II, Méhi O, Jangir PK, et al. Characterization of antibiotic resistomes by reprogrammed bacteriophage-enabled functional metagenomics in clinical strains. Nature Microbiology. 8: 410-423. PMID 36759752 DOI: 10.1038/s41564-023-01320-2  0.728
2023 Grézal G, Spohn R, Méhi O, Dunai A, Lázár V, Bálint B, Nagy I, Pál C, Papp B. Plasticity and stereotypic rewiring of the transcriptome upon bacterial evolution of antibiotic resistance. Molecular Biology and Evolution. PMID 36718533 DOI: 10.1093/molbev/msad020  0.379
2022 Farkas Z, Kovács K, Sarkadi Z, Kalapis D, Fekete G, Birtyik F, Ayaydin F, Molnár C, Horváth P, Pál C, Papp B. Gene loss and compensatory evolution promotes the emergence of morphological novelties in budding yeast. Nature Ecology & Evolution. PMID 35484218 DOI: 10.1038/s41559-022-01730-1  0.301
2022 Györkei Á, Daruka L, Balogh D, Őszi E, Magyar Z, Szappanos B, Fekete G, Fuxreiter M, Horváth P, Pál C, Kintses B, Papp B. Proteome-wide landscape of solubility limits in a bacterial cell. Scientific Reports. 12: 6547. PMID 35449391 DOI: 10.1038/s41598-022-10427-1  0.677
2020 Kovács K, Farkas Z, Bajić D, Kalapis D, Daraba A, Almási K, Kintses B, Bódi Z, Notebaart RA, Poyatos JF, Kemmeren P, Holstege FCP, Pál C, Papp B. Suboptimal Global Transcriptional Response Increases the Harmful Effects of Loss-of-Function Mutations. Molecular Biology and Evolution. PMID 33306797 DOI: 10.1093/molbev/msaa280  0.708
2020 Bálint A, Farkas K, Méhi O, Kintses B, Vásárhelyi BM, Ari E, Pál C, Madácsy T, Maléth J, Szántó KJ, Nagy I, Rutka M, Bacsur P, Szűcs D, Szepes Z, et al. Functional Anatomical Changes in Ulcerative Colitis Patients Determine Their Gut Microbiota Composition and Consequently the Possible Treatment Outcome. Pharmaceuticals (Basel, Switzerland). 13. PMID 33126430 DOI: 10.3390/ph13110346  0.662
2020 Nyerges A, Tomašič T, Durcik M, Revesz T, Szili P, Draskovits G, Bogar F, Skok Ž, Zidar N, Ilaš J, Zega A, Kikelj D, Daruka L, Kintses B, Vasarhelyi B, ... ... Pal C, et al. Rational design of balanced dual-targeting antibiotics with limited resistance. Plos Biology. 18: e3000819. PMID 33017402 DOI: 10.1371/journal.pbio.3000819  0.718
2020 Csörgő B, Nyerges A, Pál C. Targeted mutagenesis of multiple chromosomal regions in microbes. Current Opinion in Microbiology. 57: 22-30. PMID 32599531 DOI: 10.1016/J.Mib.2020.05.010  0.366
2020 Wannier TM, Nyerges A, Kuchwara HM, Czikkely M, Balogh D, Filsinger GT, Borders NC, Gregg CJ, Lajoie MJ, Rios X, Pál C, Church GM. Improved bacterial recombineering by parallelized protein discovery. Proceedings of the National Academy of Sciences of the United States of America. PMID 32467157 DOI: 10.1073/Pnas.2001588117  0.374
2020 Lamut A, Skok Ž, Barančoková M, Gutierrez LJ, Cruz CD, Tammela P, Draskovits G, Szili PÉ, Nyerges Á, Pál C, Molek P, Bratkovič T, Ilaš J, Zidar N, Zega A, et al. Second generation 4,5,6,7-tetrahydrobenzo[]thiazoles as novel DNA gyrase inhibitors. Future Medicinal Chemistry. PMID 32043377 DOI: 10.4155/Fmc-2019-0127  0.322
2019 Kintses B, Jangir PK, Fekete G, Számel M, Méhi O, Spohn R, Daruka L, Martins A, Hosseinnia A, Gagarinova A, Kim S, Phanse S, Csörgő B, Györkei Á, Ari E, et al. Chemical-genetic profiling reveals limited cross-resistance between antimicrobial peptides with different modes of action. Nature Communications. 10: 5731. PMID 31844052 DOI: 10.1038/S41467-019-13618-Z  0.739
2019 Hueso-Gil A, Nyerges A, Pal C, Calles B, de Lorenzo V. Multiple-site diversification of regulatory sequences enables inter-species operability of genetic devices. Acs Synthetic Biology. PMID 31794196 DOI: 10.1021/Acssynbio.9B00375  0.363
2019 Kikelj D, Fois B, Skok Ž, Tomašič T, Ilaš J, Zidar N, Zega A, Peterlin Mašič L, Szili P, Draskovits G, Nyerges Á, Pal C. Dual Escherichia coli DNA Gyrase A and B Inhibitors with Antibacterial Activity. Chemmedchem. PMID 31721445 DOI: 10.1002/Cmdc.201900607  0.339
2019 Spohn R, Daruka L, Lázár V, Martins A, Vidovics F, Grézal G, Méhi O, Kintses B, Számel M, Jangir PK, Csörgő B, Györkei Á, Bódi Z, Faragó A, Bodai L, et al. Integrated evolutionary analysis reveals antimicrobial peptides with limited resistance. Nature Communications. 10: 4538. PMID 31586049 DOI: 10.1038/S41467-019-12364-6  0.752
2019 Dunai A, Spohn R, Farkas Z, Lazar V, Gyorkei A, Apjok G, Boross G, Szappanos B, Grezal G, Farago A, Bodai L, Papp B, Pal C. Rapid decline of bacterial drug-resistance in an antibiotic-free environment through phenotypic reversion. Elife. 8. PMID 31418687 DOI: 10.7554/Elife.47088  0.443
2019 Szili P, Draskovits G, Révész T, Bogar F, Balogh D, Martinek T, Daruka L, Spohn R, Vásárhelyi BM, Czikkely M, Kintses B, Grézal G, Ferenc G, Pál C, Nyerges Á. Rapid evolution of reduced susceptibility against a balanced dual-targeting antibiotic through stepping-stone mutations. Antimicrobial Agents and Chemotherapy. PMID 31235632 DOI: 10.1128/Aac.00207-19  0.746
2019 Apjok G, Boross G, Nyerges Á, Fekete G, Lázár V, Papp B, Pál C, Csörgő B. Limited evolutionary conservation of the phenotypic effects of antibiotic resistance mutations. Molecular Biology and Evolution. PMID 31058961 DOI: 10.1093/Molbev/Msz109  0.463
2019 Nyerges Á, Bálint B, Cseklye J, Nagy I, Pál C, Fehér T. CRISPR-interference-based modulation of mobile genetic elements in bacteria. Synthetic Biology (Oxford, England). 4: ysz008. PMID 31008359 DOI: 10.1093/Synbio/Ysz008  0.369
2019 Kaminski Strauss S, Schirman D, Jona G, Brooks AN, Kunjapur AM, Nguyen Ba AN, Flint A, Solt A, Mershin A, Dixit A, Yona AH, Csörgő B, Busby BP, Hennig BP, Pál C, et al. Evolthon: A community endeavor to evolve lab evolution. Plos Biology. 17: e3000182. PMID 30925180 DOI: 10.1371/Journal.Pbio.3000182  0.338
2019 Manczinger M, Boross G, Kemény L, Müller V, Lenz TL, Papp B, Pál C. Pathogen diversity drives the evolution of generalist MHC-II alleles in human populations. Plos Biology. 17: e3000131. PMID 30703088 DOI: 10.1371/Journal.Pbio.3000131  0.311
2019 Dunai A, Spohn R, Farkas Z, Lázár V, Györkei Á, Apjok G, Boross G, Szappanos B, Grézal G, Faragó A, Bodai L, Papp B, Pál C. Author response: Rapid decline of bacterial drug-resistance in an antibiotic-free environment through phenotypic reversion Elife. DOI: 10.7554/Elife.47088.024  0.385
2018 Kintses B, Méhi O, Ari E, Számel M, Györkei Á, Jangir PK, Nagy I, Pál F, Fekete G, Tengölics R, Nyerges Á, Likó I, Bálint A, Molnár T, Bálint B, et al. Phylogenetic barriers to horizontal transfer of antimicrobial peptide resistance genes in the human gut microbiota. Nature Microbiology. PMID 30559406 DOI: 10.1038/S41564-018-0313-5  0.761
2018 Nyerges Á, Csörgő B, Draskovits G, Kintses B, Szili P, Ferenc G, Révész T, Ari E, Nagy I, Bálint B, Vásárhelyi BM, Bihari P, Számel M, Balogh D, Papp H, et al. Directed evolution of multiple genomic loci allows the prediction of antibiotic resistance. Proceedings of the National Academy of Sciences of the United States of America. PMID 29871954 DOI: 10.1073/Pnas.1801646115  0.748
2018 Lázár V, Martins A, Spohn R, Daruka L, Grézal G, Fekete G, Számel M, Jangir PK, Kintses B, Csörgő B, Nyerges Á, Györkei Á, Kincses A, Dér A, Walter FR, et al. Antibiotic-resistant bacteria show widespread collateral sensitivity to antimicrobial peptides. Nature Microbiology. 3: 718-731. PMID 29795541 DOI: 10.1038/S41564-018-0164-0  0.734
2018 Durcik M, Lovison D, Skok Ž, Durante Cruz C, Tammela P, Tomašič T, Benedetto Tiz D, Draskovits G, Nyerges Á, Pál C, Ilaš J, Peterlin Mašič L, Kikelj D, Zidar N. New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity. European Journal of Medicinal Chemistry. 154: 117-132. PMID 29778894 DOI: 10.1016/J.Ejmech.2018.05.011  0.308
2018 Natan E, Endoh T, Haim-Vilmovsky L, Flock T, Chalancon G, Hopper JTS, Kintses B, Horvath P, Daruka L, Fekete G, Pál C, Papp B, Oszi E, Magyar Z, Marsh JA, et al. Cotranslational protein assembly imposes evolutionary constraints on homomeric proteins. Nature Structural & Molecular Biology. PMID 29434345 DOI: 10.1038/S41594-018-0029-5  0.678
2018 Farkas Z, Kalapis D, Bódi Z, Szamecz B, Daraba A, Almási K, Kovács K, Boross G, Pál F, Horváth P, Balassa T, Molnár C, Pettkó-Szandtner A, Klement É, Rutkai E, et al. Hsp70-associated chaperones have a critical role in buffering protein production costs. Elife. 7. PMID 29377792 DOI: 10.7554/Elife.29845  0.305
2017 Ricaurte DE, Martínez-García E, Nyerges Á, Pál C, de Lorenzo V, Aparicio T. A standardized workflow for surveying recombinases expands bacterial genome-editing capabilities. Microbial Biotechnology. PMID 29094478 DOI: 10.1111/1751-7915.12846  0.406
2017 Pál C, Papp B. Evolution of complex adaptations in molecular systems. Nature Ecology & Evolution. 1: 1084-1092. PMID 28782044 DOI: 10.1038/S41559-017-0228-1  0.302
2017 Bódi Z, Farkas Z, Nevozhay D, Kalapis D, Lázár V, Csörgő B, Nyerges Á, Szamecz B, Fekete G, Papp B, Araújo H, Oliveira JL, Moura G, Santos MAS, Székely T, et al. Phenotypic heterogeneity promotes adaptive evolution. Plos Biology. 15: e2000644. PMID 28486496 DOI: 10.1371/Journal.Pbio.2000644  0.389
2017 Umenhoffer K, Draskovits G, Nyerges Á, Karcagi I, Bogos B, Tímár E, Csörgő B, Herczeg R, Nagy I, Fehér T, Pal C, Posfai G. Genome-wide abolishment of mobile genetic elements using genome shuffling and CRISPR/Cas-assisted MAGE allows the efficient stabilization of a bacterial chassis. Acs Synthetic Biology. PMID 28426191 DOI: 10.1021/Acssynbio.6B00378  0.363
2016 Szappanos B, Fritzemeier J, Csörgő B, Lázár V, Lu X, Fekete G, Bálint B, Herczeg R, Nagy I, Notebaart RA, Lercher MJ, Pál C, Papp B. Adaptive evolution of complex innovations through stepwise metabolic niche expansion. Nature Communications. 7: 11607. PMID 27197754 DOI: 10.1038/Ncomms11607  0.319
2016 Diao J, Charlebois DA, Nevozhay D, Bódi Z, Pál C, Balázsi G. Efflux Pump Control Alters Synthetic Gene Circuit Function. Acs Synthetic Biology. PMID 27111147 DOI: 10.1021/Acssynbio.5B00154  0.338
2016 Nyerges Á, Csörgő B, Nagy I, Bálint B, Bihari P, Lázár V, Apjok G, Umenhoffer K, Bogos B, Pósfai G, Pál C. A highly precise and portable genome engineering method allows comparison of mutational effects across bacterial species. Proceedings of the National Academy of Sciences of the United States of America. PMID 26884157 DOI: 10.1073/Pnas.1520040113  0.413
2016 Karcagi I, Draskovits G, Umenhoffer K, Fekete G, Kovács K, Méhi O, Balikó G, Szappanos B, Györfy Z, Fehér T, Bogos B, Blattner FR, Pál C, Pósfai G, Papp B. Indispensability of horizontally transferred genes and its impact on bacterial genome streamlining. Molecular Biology and Evolution. PMID 26769030 DOI: 10.1093/Molbev/Msw009  0.356
2015 Kalapis D, Bezerra AR, Farkas Z, Horvath P, Bódi Z, Daraba A, Szamecz B, Gut I, Bayes M, Santos MA, Pál C. Evolution of Robustness to Protein Mistranslation by Accelerated Protein Turnover. Plos Biology. 13: e1002291. PMID 26544557 DOI: 10.1371/Journal.Pbio.1002291  0.356
2015 Pál C, Papp B, Lázár V. Collateral sensitivity of antibiotic-resistant microbes. Trends in Microbiology. 23: 401-7. PMID 25818802 DOI: 10.1016/J.Tim.2015.02.009  0.451
2014 Szamecz B, Boross G, Kalapis D, Kovács K, Fekete G, Farkas Z, Lázár V, Hrtyan M, Kemmeren P, Groot Koerkamp MJ, Rutkai E, Holstege FC, Papp B, Pál C. The genomic landscape of compensatory evolution. Plos Biology. 12: e1001935. PMID 25157590 DOI: 10.1371/Journal.Pbio.1001935  0.421
2014 Notebaart RA, Szappanos B, Kintses B, Pál F, Györkei Á, Bogos B, Lázár V, Spohn R, CsörgÅ‘ B, Wagner A, Ruppin E, Pál C, Papp B. Network-level architecture and the evolutionary potential of underground metabolism. Proceedings of the National Academy of Sciences of the United States of America. 111: 11762-7. PMID 25071190 DOI: 10.1073/Pnas.1406102111  0.698
2014 Méhi O, Bogos B, Csörgő B, Pál F, Nyerges A, Papp B, Pál C. Perturbation of iron homeostasis promotes the evolution of antibiotic resistance. Molecular Biology and Evolution. 31: 2793-804. PMID 25063442 DOI: 10.1093/Molbev/Msu223  0.394
2014 Lázár V, Nagy I, Spohn R, Csörg? B, Györkei Á, Nyerges Á, Horváth B, Vörös A, Busa-Fekete R, Hrtyan M, Bogos B, Méhi O, Fekete G, Szappanos B, Kégl B, et al. Genome-wide analysis captures the determinants of the antibiotic cross-resistance interaction network. Nature Communications. 5: 4352. PMID 25000950 DOI: 10.1038/Ncomms5352  0.471
2014 Pál C, Papp B, Pósfai G. The dawn of evolutionary genome engineering. Nature Reviews. Genetics. 15: 504-12. PMID 24866756 DOI: 10.1038/Nrg3746  0.312
2014 Nyerges Á, CsorgÅ‘ B, Nagy I, Latinovics D, Szamecz B, Pósfai G, Pál C. Conditional DNA repair mutants enable highly precise genome engineering. Nucleic Acids Research. 42: e62. PMID 24500200 DOI: 10.1093/Nar/Gku105  0.333
2013 Lázár V, Pal Singh G, Spohn R, Nagy I, Horváth B, Hrtyan M, Busa-Fekete R, Bogos B, Méhi O, CsörgÅ‘ B, Pósfai G, Fekete G, Szappanos B, Kégl B, Papp B, et al. Bacterial evolution of antibiotic hypersensitivity. Molecular Systems Biology. 9: 700. PMID 24169403 DOI: 10.1038/Msb.2013.57  0.463
2013 Pál C, Papp B. From passengers to drivers: Impact of bacterial transposable elements on evolvability. Mobile Genetic Elements. 3: e23617. PMID 23734296 DOI: 10.4161/Mge.23617  0.369
2013 Méhi O, Bogos B, Csörgo B, Pál C. Genomewide screen for modulators of evolvability under toxic antibiotic exposure. Antimicrobial Agents and Chemotherapy. 57: 3453-6. PMID 23669383 DOI: 10.1128/Aac.02454-12  0.431
2012 Fehér T, Bogos B, Méhi O, Fekete G, Csörgo B, Kovács K, Pósfai G, Papp B, Hurst LD, Pál C. Competition between transposable elements and mutator genes in bacteria. Molecular Biology and Evolution. 29: 3153-9. PMID 22527906 DOI: 10.1093/Molbev/Mss122  0.556
2011 Papp B, Notebaart RA, Pál C. Systems-biology approaches for predicting genomic evolution. Nature Reviews. Genetics. 12: 591-602. PMID 21808261 DOI: 10.1038/Nrg3033  0.323
2011 Szappanos B, Kovács K, Szamecz B, Honti F, Costanzo M, Baryshnikova A, Gelius-Dietrich G, Lercher MJ, Jelasity M, Myers CL, Andrews BJ, Boone C, Oliver SG, Pál C, Papp B. An integrated approach to characterize genetic interaction networks in yeast metabolism. Nature Genetics. 43: 656-62. PMID 21623372 DOI: 10.1038/Ng.846  0.324
2010 Costanzo M, Baryshnikova A, Bellay J, Kim Y, Spear ED, Sevier CS, Ding H, Koh JL, Toufighi K, Mostafavi S, Prinz J, St Onge RP, VanderSluis B, Makhnevych T, Vizeacoumar FJ, et al. The genetic landscape of a cell. Science (New York, N.Y.). 327: 425-31. PMID 20093466 DOI: 10.1126/Science.1180823  0.335
2008 Lercher MJ, Pál C. Integration of horizontally transferred genes into regulatory interaction networks takes many million years. Molecular Biology and Evolution. 25: 559-67. PMID 18158322 DOI: 10.1093/Molbev/Msm283  0.371
2007 Pal C, Maciá MD, Oliver A, Schachar I, Buckling A. Coevolution with viruses drives the evolution of bacterial mutation rates. Nature. 450: 1079-81. PMID 18059461 DOI: 10.1038/Nature06350  0.333
2007 Harrison R, Papp B, Pál C, Oliver SG, Delneri D. Plasticity of genetic interactions in metabolic networks of yeast Proceedings of the National Academy of Sciences of the United States of America. 104: 2307-2312. PMID 17284612 DOI: 10.1073/Pnas.0607153104  0.379
2007 Morgan AD, Brockhurst MA, Lopez-Pascua LD, Pal C, Buckling A. Differential impact of simultaneous migration on coevolving hosts and parasites. Bmc Evolutionary Biology. 7: 1. PMID 17214884 DOI: 10.1186/1471-2148-7-1  0.313
2006 Pál C, Papp B, Lercher MJ. An integrated view of protein evolution. Nature Reviews. Genetics. 7: 337-48. PMID 16619049 DOI: 10.1038/Nrg1838  0.361
2006 Pál C, Papp B, Lercher MJ, Csermely P, Oliver SG, Hurst LD. Chance and necessity in the evolution of minimal metabolic networks. Nature. 440: 667-70. PMID 16572170 DOI: 10.1038/Nature04568  0.563
2005 Pál C, Papp B, Lercher MJ. Adaptive evolution of bacterial metabolic networks by horizontal gene transfer. Nature Genetics. 37: 1372-5. PMID 16311593 DOI: 10.1038/Ng1686  0.355
2005 Pál C, Papp B, Lercher MJ. Horizontal gene transfer depends on gene content of the host. Bioinformatics (Oxford, England). 21: ii222-3. PMID 16204108 DOI: 10.1093/Bioinformatics/Bti1136  0.374
2005 Hurst LD, Pál C. Dissecting dispensability. Nature Genetics. 37: 214-5. PMID 15731753 DOI: 10.1038/ng0305-214  0.367
2004 Papp B, Pál C, Hurst LD. Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast. Nature. 429: 661-4. PMID 15190353 DOI: 10.1038/Nature02636  0.549
2004 Pál C, Hurst LD. Evidence against the selfish operon theory. Trends in Genetics : Tig. 20: 232-4. PMID 15145575 DOI: 10.1016/J.Tig.2004.04.001  0.554
2004 Hurst LD, Pál C, Lercher MJ. The evolutionary dynamics of eukaryotic gene order. Nature Reviews. Genetics. 5: 299-310. PMID 15131653 DOI: 10.1038/Nrg1319  0.556
2003 Papp B, Pál C, Hurst LD. Evolution of cis-regulatory elements in duplicated genes of yeast. Trends in Genetics : Tig. 19: 417-22. PMID 12902158 DOI: 10.1016/S0168-9525(03)00174-4  0.565
2003 Papp B, Pál C, Hurst LD. Dosage sensitivity and the evolution of gene families in yeast. Nature. 424: 194-7. PMID 12853957 DOI: 10.1038/Nature01771  0.551
2003 Pál C, Hurst LD. Evidence for co-evolution of gene order and recombination rate. Nature Genetics. 33: 392-5. PMID 12577060 DOI: 10.1038/Ng1111  0.533
2003 Pál C, Papp B, Hurst LD, Hirsh AE, Fraser HB. Genomic function: Rate of evolution and gene dispensability Nature. 421: 496-498. PMID 12556881 DOI: 10.1038/421496B  0.551
2002 Hurst LD, Williams EJ, Pál C. Natural selection promotes the conservation of linkage of co-expressed genes. Trends in Genetics : Tig. 18: 604-6. PMID 12446137 DOI: 10.1016/S0168-9525(02)02813-5  0.544
2001 Pál C, Papp B, Hurst LD. Does the Recombination Rate Affect the Efficiency of Purifying Selection? The Yeast Genome Provides a Partial Answer Molecular Biology and Evolution. 18: 2323-2326. PMID 11719582 DOI: 10.1093/Oxfordjournals.Molbev.A003779  0.372
2001 Szathmáry E, Jordán F, Pál C. Can Genes Explain Biological Complexity Science. 292: 1315-1316. PMID 11360989 DOI: 10.1126/Science.1060852  0.327
2001 Hurst LD, Pál C. Evidence for purifying selection acting on silent sites in BRCA1 Trends in Genetics. 17: 62-65. PMID 11173101 DOI: 10.1016/S0168-9525(00)02173-9  0.305
2000 Williams EJ, Pal C, Hurst LD. The molecular evolution of signal peptides. Gene. 253: 313-22. PMID 10940569 DOI: 10.1016/S0378-1119(00)00233-X  0.509
2000 Pál C, Hurst LD. The evolution of gene number: are heritable and non-heritable errors equally important? Heredity. 84: 393-400. PMID 10849062 DOI: 10.1046/J.1365-2540.2000.00725.X  0.354
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