Year |
Citation |
Score |
2023 |
Borgelt L, Hohnen L, Pallesen JS, Hommen P, Goebel GL, Bosica F, Liu Y, O'Mahony G, Wu P. -Biphenyl Pyrrolinones and Dibenzofurans as RNA-Binding Protein LIN28 Inhibitors Disrupting the LIN28- Interaction. Acs Medicinal Chemistry Letters. 14: 1707-1715. PMID 38116413 DOI: 10.1021/acsmedchemlett.3c00341 |
0.841 |
|
2023 |
Borgelt L, Wu P. Targeting Ribonucleases with Small Molecules and Bifunctional Molecules. Acs Chemical Biology. PMID 37382390 DOI: 10.1021/acschembio.3c00191 |
0.575 |
|
2023 |
Hommen P, Hwang J, Huang F, Borgelt L, Hohnen L, Wu P. Chromenopyrazole-peptide conjugates as small-molecule based inhibitors disrupting the protein-RNA interaction of LIN28-let-7. Chembiochem : a European Journal of Chemical Biology. e202300376. PMID 37224100 DOI: 10.1002/cbic.202300376 |
0.785 |
|
2023 |
Hwang J, Haacke N, Borgelt L, Qiu X, Gasper R, Wu P. Rational design and evaluation of 2-((pyrrol-2-yl)methylene)thiophen-4-ones as RNase L inhibitors. European Journal of Medicinal Chemistry. 256: 115439. PMID 37201427 DOI: 10.1016/j.ejmech.2023.115439 |
0.832 |
|
2023 |
Borgelt L, Huang F, Hohnen L, Qiu X, Goebel GL, Hommen P, Wu P. Spirocyclic Chromenopyrazole Inhibitors Disrupting the Interaction between the RNA-binding protein LIN28 and Let-7. Chembiochem : a European Journal of Chemical Biology. e202300168. PMID 37129525 DOI: 10.1002/cbic.202300168 |
0.818 |
|
2022 |
Borgelt L, Haacke N, Lampe P, Qiu X, Gasper R, Schiller D, Hwang J, Sievers S, Wu P. Small-molecule screening of ribonuclease L binders for RNA degradation. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 154: 113589. PMID 36029542 DOI: 10.1016/j.biopha.2022.113589 |
0.77 |
|
2022 |
Hwang J, Qiu X, Borgelt L, Haacke N, Kanis L, Petroulia S, Gasper R, Schiller D, Lampe P, Sievers S, Imig J, Wu P. Synthesis and evaluation of RNase L-binding 2-aminothiophenes as anticancer agents. Bioorganic & Medicinal Chemistry. 58: 116653. PMID 35152173 DOI: 10.1016/j.bmc.2022.116653 |
0.647 |
|
2021 |
Goebel GL, Hohnen L, Borgelt L, Hommen P, Qiu X, Lightfoot H, Wu P. Small molecules with tetrahydroquinoline-containing Povarov scaffolds as inhibitors disrupting the Protein-RNA interaction of LIN28-let-7. European Journal of Medicinal Chemistry. 228: 114014. PMID 34883291 DOI: 10.1016/j.ejmech.2021.114014 |
0.709 |
|
2021 |
Borgelt L, Li F, Hommen P, Lampe P, Hwang J, Goebel GL, Sievers S, Wu P. Trisubstituted Pyrrolinones as Small-Molecule Inhibitors Disrupting the Protein-RNA Interaction of LIN28 and . Acs Medicinal Chemistry Letters. 12: 893-898. PMID 34136077 DOI: 10.1021/acsmedchemlett.0c00546 |
0.83 |
|
2020 |
Hwang J, Borgelt L, Wu P. Multicomponent Petasis Reaction for the Synthesis of Functionalized 2-Aminothiophenes and Thienodiazepines. Acs Combinatorial Science. PMID 32985878 DOI: 10.1021/acscombsci.0c00173 |
0.696 |
|
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