Andreas Kirschning, Prof. - Publications

Affiliations: 
Institut für Organische Chemie Leibniz Universität Hannover, Hannover, Lower Saxony, Germany 
Area:
Natural products research, Flow chemistry

155 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Koller TO, Scheid U, Kösel T, Herrmann J, Krug D, Boshoff HIM, Beckert B, Evans JC, Schlemmer J, Sloan B, Weiner DM, Via LE, Moosa A, Ioerger TR, Graf M, ... ... Kirschning A, et al. The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition. Journal of the American Chemical Society. PMID 36603206 DOI: 10.1021/jacs.2c08816  0.36
2020 Kirschning A, Wesemann F, Heutling A, Wienecke P. First ring-expanded maytansin lactone accessed by a new mutasynthetic variant. Chembiochem : a European Journal of Chemical Biology. PMID 32484951 DOI: 10.1002/Cbic.202000336  0.301
2020 Harms V, Kirschning A, Dickschat JS. Nature-driven approaches to non-natural terpene analogues. Natural Product Reports. PMID 32068211 DOI: 10.1039/C9Np00055K  0.312
2020 Elgaher WAM, Hamed MM, Baumann S, Herrmann J, Siebenbürger L, Krull J, Cirnski K, Kirschning A, Brönstrup M, Müller R, Hartmann RW. Cystobactamid 507: Concise Synthesis, Mode of Action and Optimization toward More Potent Antibiotics. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31984562 DOI: 10.1002/Chem.202000117  0.445
2020 Nawasreh M, Kirschning A, Duddeck H, Dräger G, Fenske D. Novel double functional protection of cephalostatin analogues using a gas-free chlorination method. Heliyon. 6: e03025. PMID 31909240 DOI: 10.1016/J.Heliyon.2019.E03025  0.317
2020 Elgaher WAM, Hamed MM, Baumann S, Herrmann J, Siebenbürger L, Krull J, Cirnski K, Kirschning A, Brönstrup M, Müller R, Hartmann RW. Cover Feature: Cystobactamid 507: Concise Synthesis, Mode of Action, and Optimization toward More Potent Antibiotics (Chem. Eur. J. 32/2020) Chemistry: a European Journal. 26: 7141-7141. DOI: 10.1002/Chem.202002127  0.416
2019 Kirschning A, Planke T, Cirnski K, Herrmann J, Müller R. Synthetic and Biologic Studies on New Urea and Triazole Containing Cystobactamid Derivatives. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31834653 DOI: 10.1002/Chem.201904073  0.485
2019 Stepanyuk A, Kirschning A. Synthetic terpenoids in the world of fragrances: Iso E Super is the showcase. Beilstein Journal of Organic Chemistry. 15: 2590-2602. PMID 31728173 DOI: 10.3762/Bjoc.15.252  0.304
2019 Geist E, Berneaud-Kötz H, Baikstis T, Dräger G, Kirschning A. Toward Chromanes by de Novo Construction of the Benzene Ring. Organic Letters. PMID 31664844 DOI: 10.1021/Acs.Orglett.9B03209  0.322
2019 Moeller M, Norris MD, Planke T, Cirnski K, Herrmann J, Müller R, Kirschning A. Scalable Syntheses of Methoxyaspartate and Preparation of the Antibiotic Cystobactamid 861-2 and Highly Potent Derivatives. Organic Letters. PMID 31599597 DOI: 10.1021/Acs.Orglett.9B03143  0.482
2019 Banda DH, Perin PM, Brown RJP, Todt D, Solodenko W, Hoffmeyer P, Sahu KK, Houghton M, Meuleman P, Müller R, Kirschning A, Pietschmann T. A central hydrophobic E1 region controls the pH range of hepatitis C virus membrane fusion and susceptibility to fusion inhibitors. Journal of Hepatology. PMID 30769006 DOI: 10.1016/J.Jhep.2019.01.033  0.372
2019 Planke T, Moreno M, Hüttel S, Fohrer J, Gille F, Norris MD, Siebke M, Wang L, Müller R, Kirschning A. Cystobactamids 920-1 and 920-2: Assignment of the Constitution and Relative Configuration by Total Synthesis. Organic Letters. PMID 30735398 DOI: 10.1021/Acs.Orglett.9B00058  0.44
2019 Li PJ, Dräger G, Kirschning A. A General Biomimetic Hetero-Diels-Alder Approach to the Core Skeletons of Xenovulene A and the Sterhirsutins A and B. Organic Letters. PMID 30694066 DOI: 10.1021/Acs.Orglett.8B04003  0.348
2018 Dorival J, Risser F, Jacob C, Collin S, Dräger G, Paris C, Chagot B, Kirschning A, Gruez A, Weissman KJ. Insights into a dual function amide oxidase/macrocyclase from lankacidin biosynthesis. Nature Communications. 9: 3998. PMID 30266997 DOI: 10.1038/S41467-018-06323-W  0.326
2018 Kirschning A, Schröder B, Harms V, Oberhauser C, Seidel K, Ekramzadeh K, Beutel S, Dickschat J, Lauterbach L, Winkler S. Exploiting the synthetic potential of sesquiterpene cyclases for generating unnatural terpenoids. Angewandte Chemie (International Ed. in English). PMID 29953712 DOI: 10.1002/Anie.201805526  0.315
2018 Podrezova EV, Larkina MS, Belousov MV, Kirschning A, Zhdankin VV, Yusubov MS. Expedient Synthesis of Long-Chain ω-Substituted Fatty Acids and Esters from Cyclic Ketones Using Iodine and Hydrogen Peroxide Synthesis. 50: 4081-4088. DOI: 10.1055/S-0036-1591598  0.368
2018 Sommer H, Braun M, Schröder B, Kirschning A. 4-Ethoxy-1,1,1-trifluoro-3-buten-2-one (ETFBO), a Versatile Precursor for Trifluoromethyl-Substituted Heteroarenes – a Short Synthesis of Celebrex® (Celecoxib) Synlett. 29: 121-125. DOI: 10.1055/S-0036-1589097  0.368
2018 Wolling M, Kirschning A. Synthesis of the Aglycon of the Antibiotic Disciformycin European Journal of Organic Chemistry. 2018: 648-656. DOI: 10.1002/Ejoc.201701639  0.335
2017 Ammermann J, Schmidt T, Donner J, Reck M, Dalton M, Stumpp N, Stiesch M, Wagner-Döbler I, Kirschning A. The carolactam strategy is ineffective: synthesis and biological evaluation of carolactam. Organic & Biomolecular Chemistry. PMID 28972613 DOI: 10.1039/C7Ob02060K  0.303
2017 Donner J, Reck M, Bunk B, Jarek M, App CB, Meier-Kolthoff JP, Overmann J, Müller R, Kirschning A, Wagner-Döbler I. The Biofilm Inhibitor Carolacton Enters Gram-Negative Cells: Studies Using a TolC-Deficient Strain of Escherichia coli. Msphere. 2. PMID 28959742 DOI: 10.1128/mSphereDirect.00375-17  0.319
2017 Müller R, Hüttel S, Testolin G, Herrmann J, Planke T, Gille F, Moreno M, Stadler M, Brönstrup M, Kirschning A. Discovery and total synthesis of natural cystobactamid derivatives with superior activity against Gram-negative pathogens. Angewandte Chemie (International Ed. in English). PMID 28730677 DOI: 10.1002/Anie.201705913  0.466
2017 Wang LL, Kirschning A. Total synthesis of elansolids B1 and B2. Beilstein Journal of Organic Chemistry. 13: 1280-1287. PMID 28694871 DOI: 10.3762/Bjoc.13.124  0.312
2017 Kirschning A, Wang LL, Candito D, Hermann J, Müller R, Dräger G. Harnessing a p-quinone methide intermediate in the biomimetic total synthesis of the highly active antibiotic 20-deoxy-elansolid B1. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28195370 DOI: 10.1002/Chem.201605884  0.51
2017 Kipke A, Schöning K, Yusubov M, Kirschning A. TEMPO-Mediated Oxidative Deformylation of Aldehydes: Applications in the Synthesis of Polyketide Fragments European Journal of Organic Chemistry. 2017: 6906-6913. DOI: 10.1002/Ejoc.201701349  0.319
2017 Wang L, Candito D, Dräger G, Kirschning A. Synthetic Studies Probing Elansolid Biosynthesis: A para‐Quinone‐Methide‐Triggered Intramolecular Diels–Alder Reaction European Journal of Organic Chemistry. 2017: 5582-5591. DOI: 10.1002/Ejoc.201701125  0.355
2017 Hüttel S, Testolin G, Herrmann J, Planke T, Gille F, Moreno M, Stadler M, Brönstrup M, Kirschning A, Müller R. Entdeckung und Totalsynthese von natürlichen Cystobactamid-Derivaten mit herausragender Aktivität gegen Gram-negative Pathogene Angewandte Chemie. 129: 12934-12938. DOI: 10.1002/Ange.201705913  0.368
2017 Yusubov MS, Postnikov PS, Yusubova RY, Yoshimura A, Jürjens G, Kirschning A, Zhdankin VV. 2-Iodoxybenzoic Acid Tosylates: the Alternative to Dess–Martin Periodinane Oxidizing Reagents Advanced Synthesis & Catalysis. 359: 3207-3216. DOI: 10.1002/Adsc.201700776  0.302
2016 Busch T, Dräger G, Kunst E, Benson H, Sasse F, Siems K, Kirschning A. Synthesis and antiproliferative activity of new tonantzitlolone-derived diterpene derivatives. Organic & Biomolecular Chemistry. PMID 27604289 DOI: 10.1039/C6Ob01697A  0.336
2016 Donner J, Reck M, Bergmann S, Kirschning A, Müller R, Wagner-Döbler I. The biofilm inhibitor Carolacton inhibits planktonic growth of virulent pneumococci via a conserved target. Scientific Reports. 6: 29677. PMID 27404808 DOI: 10.1038/Srep29677  0.414
2016 Gille F, Kirschning A. Studies on the synthesis of peptides containing dehydrovaline and dehydroisoleucine based on copper-mediated enamide formation. Beilstein Journal of Organic Chemistry. 12: 564-70. PMID 27340448 DOI: 10.3762/Bjoc.12.55  0.311
2015 Bułyszko I, Dräger G, Klenge A, Kirschning A. Evaluation of the Synthetic Potential of an AHBA Knockout Mutant of the Rifamycin Producer Amycolatopsis mediterranei. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26559164 DOI: 10.1002/Chem.201503548  0.366
2015 Perin PM, Haid S, Brown RJ, Doerrbecker J, Schulze K, Zeilinger C, von Schaewen M, Heller B, Vercauteren K, Luxenburger E, Baktash YM, Vondran FW, Speerstra S, Awadh A, Mukhtarov F, ... ... Kirschning A, et al. Flunarizine prevents hepatitis C virus membrane fusion in a genotype-dependent manner by targeting the potential fusion peptide within E1. Hepatology (Baltimore, Md.). PMID 26248546 DOI: 10.1002/Hep.28111  0.372
2015 Stumpp N, Premnath P, Schmidt T, Ammermann J, Dräger G, Reck M, Jansen R, Stiesch M, Wagner-Döbler I, Kirschning A. Synthesis of new carolacton derivatives and their activity against biofilms of oral bacteria. Organic & Biomolecular Chemistry. 13: 5765-74. PMID 25902328 DOI: 10.1039/C5Ob00460H  0.323
2015 Jürjens G, Kirschning A, Candito DA. Lessons from the Synthetic Chemist Nature Natural Product Reports. 32: 723-737. PMID 25728458 DOI: 10.1039/C4Np00160E  0.335
2015 Franke J, Bock M, Dehn R, Fohrer J, Mhaske SB, Migliorini A, Kanakis AA, Jansen R, Herrmann J, Müller R, Kirschning A. Total and semi-syntheses of antimicrobial thuggacin derivatives. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 4272-84. PMID 25652819 DOI: 10.1002/Chem.201405874  0.452
2015 Moreno M, Elgaher WAM, Herrmann J, Schläger N, Hamed MM, Baumann S, Müller R, Hartmann RW, Kirschning A. Synthesis and biological evaluation of cystobactamid 507: A bacterial topoisomerase inhibitor from Cystobacter sp. Synlett. 26: 1175-1178. DOI: 10.1055/S-0034-1380509  0.486
2015 Perin P, Haid S, Brown R, Schulze K, Colpitts C, Zeilinger C, von Schaewen M, Heller B, Vercauteren K, Luxenburger E, Andonyadis Y, Vondran F, Kirschning A, Schang L, Müller R, et al. P0674 : Clinically approved T-type calcium channel inhibitors prevent hepatitis C virus (HCV) membrane fusion in a genotype-dependent manner Journal of Hepatology. 62: S574-S575. DOI: 10.1016/S0168-8278(15)30878-3  0.356
2015 Franke J, Bock M, Dehn R, Fohrer J, Mhaske SB, Migliorini A, Kanakis AA, Jansen R, Herrmann J, Müller R, Kirschning A. Frontispiece: Total and Semi-Syntheses of Antimicrobial Thuggacin Derivatives Chemistry - a European Journal. 21: n/a-n/a. DOI: 10.1002/Chem.201581162  0.461
2014 Jürjens G, Kirschning A. Synthesis of a cytotoxic ansamycin hybrid Organic Letters. 16: 3000-3003. PMID 24874463 DOI: 10.1021/Ol5011278  0.346
2014 Harmrolfs K, Mancuso L, Drung B, Sasse F, Kirschning A. Preparation of new alkyne-modified ansamitocins by mutasynthesis. Beilstein Journal of Organic Chemistry. 10: 535-43. PMID 24605171 DOI: 10.3762/Bjoc.10.49  0.364
2014 Weber A, Dehn R, Schläger N, Dieter B, Kirschning A. Total synthesis of the antibiotic elansolid B1. Organic Letters. 16: 568-71. PMID 24393030 DOI: 10.1021/Ol403441C  0.343
2013 Mancuso L, Jürjens G, Hermane J, Harmrolfs K, Eichner S, Fohrer J, Collisi W, Sasse F, Kirschning A. Bioreduction of aryl azides during mutasynthesis of new ansamitocins Organic Letters. 15: 4442-4445. PMID 23981134 DOI: 10.1021/Ol401989E  0.315
2013 Kupracz L, Kirschning A. Two-step flow synthesis of biarylmethanes by reductive arylation of tosylhydrazones Journal of Flow Chemistry. 3: 11-16. DOI: 10.1556/Jfc-D-12-00021  0.366
2013 Solodenko W, Doppiu A, Frankfurter R, Vogt C, Kirschning A. Silica immobilized Hoveyda type pre-catalysts: Convenient and reusable heterogeneous catalysts for batch and flow olefin metathesis Australian Journal of Chemistry. 66: 183-191. DOI: 10.1071/Ch12434  0.302
2013 Kupracz L, Kirschning A. Multiple organolithium generation in the continuous flow synthesis of amitriptyline Advanced Synthesis and Catalysis. 355: 3375-3380. DOI: 10.1002/Adsc.201300614  0.305
2012 Borré E, Rouen M, Laurent I, Magrez M, Caijo F, Crévisy C, Solodenko W, Toupet L, Frankfurter R, Vogt C, Kirschning A, Mauduit M. A fast-initiating ionically tagged ruthenium complex: a robust supported pre-catalyst for batch-process and continuous-flow olefin metathesis. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 16369-82. PMID 23090846 DOI: 10.1002/Chem.201201589  0.302
2012 Knobloch T, Dräger G, Collisi W, Sasse F, Kirschning A. Unprecedented deoxygenation at C-7 of the ansamitocin core during mutasynthetic biotransformations. Beilstein Journal of Organic Chemistry. 8: 861-9. PMID 23015834 DOI: 10.3762/Bjoc.8.96  0.3
2012 Schläger N, Kirschning A. Substrate-controlled stereoselectivity in the Yamamoto aldol reaction Organic and Biomolecular Chemistry. 10: 7721-7729. PMID 22898755 DOI: 10.1039/C2Ob26185E  0.336
2012 Steinmetz H, Zander W, Shushni MAM, Jansen R, Gerth K, Dehn R, Dräger G, Kirschning A, Müller R. Precursor-Directed Syntheses and Biological Evaluation of New Elansolid Derivatives Chembiochem. 13: 1813-1817. PMID 22807264 DOI: 10.1002/Cbic.201200228  0.472
2012 Kirschning A, Hahn F. Merging chemical synthesis and biosynthesis: A new chapter in the total synthesis of natural products and natural product libraries Angewandte Chemie - International Edition. 51: 4012-4022. PMID 22441812 DOI: 10.1002/Anie.201107386  0.553
2012 Wegner J, Ley SV, Kirschning A, Hansen AL, Garcia JM, Baxendale IR. A total synthesis of millingtonine A. Organic Letters. 14: 696-9. PMID 22260734 DOI: 10.1021/Ol203158P  0.368
2012 Taft F, Harmrolfs K, Nickeleit I, Heutling A, Kiene M, Malek N, Sasse F, Kirschning A. Combined muta- and semisynthesis: A powerful synthetic hybrid approach to access target specific antitumor agents based on ansamitocin P3 Chemistry - a European Journal. 18: 880-886. PMID 22170289 DOI: 10.1002/Chem.201101640  0.316
2012 Schmidt T, Kirschning A. Total synthesis of carolacton, a highly potent biofilm inhibitor Angewandte Chemie - International Edition. 51: 1063-1066. PMID 22162345 DOI: 10.1002/Anie.201106762  0.311
2012 Eichner S, Eichner T, Floss HG, Fohrer J, Hofer E, Sasse F, Zeilinger C, Kirschning A. Broad substrate specificity of the amide synthase in S. hygroscopicus--new 20-membered macrolactones derived from geldanamycin. Journal of the American Chemical Society. 134: 1673-9. PMID 22136518 DOI: 10.1021/Ja2087147  0.555
2012 Eichner S, Knobloch T, Floss HG, Fohrer J, Harmrolfs K, Hermane J, Schulz A, Sasse F, Spiteller P, Taft F, Kirschning A. The interplay between mutasynthesis and semisynthesis: generation and evaluation of an ansamitocin library. Angewandte Chemie (International Ed. in English). 51: 752-7. PMID 22135226 DOI: 10.1002/Anie.201106249  0.446
2012 Schön U, Messinger J, Solodenko W, Kirschning A. Synthetic approaches towards 4-functionalized estrone derivatives Synthesis (Germany). 44: 3822-3828. DOI: 10.1055/S-0032-1316816  0.347
2012 Taft F, Eichner S, Knobloch T, Harmrolfs K, Hermane J, Kirschning A. Ansamitocin libraries by combining mutasynthesis with chemical synthesis; A new version of total synthesis Synlett. 23: 1416-1426. DOI: 10.1055/S-0031-1290695  0.338
2012 Kirschning A, Hahn F. Vereinigung von chemischer Synthese und Biosynthese: ein neues Kapitel in der Totalsynthese von Naturstoffen und Naturstoffbibliotheken Angewandte Chemie. 124: 4086-4096. DOI: 10.1002/Ange.201107386  0.53
2011 Knobloch T, Harmrolfs K, Taft F, Thomaszewski B, Sasse F, Kirschning A. Mutational Biosynthesis of Ansamitocin Antibiotics: A Diversity-Oriented Approach to Exploit Biosynthetic Flexibility Chembiochem. 12: 540-547. PMID 22238146 DOI: 10.1002/Cbic.201000608  0.337
2011 Kupracz L, Hartwig J, Wegner J, Ceylan S, Kirschning A. Multistep flow synthesis of vinyl azides and their use in the copper-catalyzed Huisgen-type cycloaddition under inductive-heating conditions. Beilstein Journal of Organic Chemistry. 7: 1441-8. PMID 22049302 DOI: 10.3762/Bjoc.7.168  0.357
2011 Jansen R, Gerth K, Steinmetz H, Reinecke S, Kessler W, Kirschning A, Müller R. Elansolid A3, a unique p-quinone methide antibiotic from Chitinophaga sancti. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 7739-44. PMID 21626585 DOI: 10.1002/Chem.201100457  0.375
2011 Dehn R, Katsuyama Y, Weber A, Gerth K, Jansen R, Steinmetz H, Höfle G, Müller R, Kirschning A. Molecular basis of elansolid biosynthesis: Evidence for an unprecedented quinone methide initiated intramolecular diels-alder cycloaddition/ macrolactonization Angewandte Chemie - International Edition. 50: 3882-3887. PMID 21472917 DOI: 10.1002/Anie.201006880  0.435
2011 Steinmetz H, Gerth K, Jansen R, Dehn R, Reinecke S, Kirschning A, Müller R. Elansolid A, a Unique Macrolide Antibiotic from Chitinophaga sancti Isolated as Two Stable Atropisomers Angewandte Chemie - International Edition. 50: 532-536. PMID 21154488 DOI: 10.1002/Anie.201005226  0.378
2011 Paleček J, Dräger G, Kirschning A. A practical large-scale synthesis of cyclic RGD pentapeptides suitable for further functionalization through click' chemistry Synthesis. 653-661. DOI: 10.1055/S-0030-1258396  0.318
2011 Barbier J, Jansen R, Irschik H, Benson S, Gerth K, Böhlendorf B, Höfle G, Reichenbach H, Wegner J, Zeilinger C, Kirschning A, Müller R. Isolierung und Totalsynthese der Icumazole und Noricumazole - antimykotische Antibiotika und Kationenkanalblocker aus Sorangium cellulosum Angewandte Chemie. 124: 1282-1286. DOI: 10.1002/Ange.201106435  0.371
2011 Dehn R, Katsuyama Y, Weber A, Gerth K, Jansen R, Steinmetz H, Höfle G, Müller R, Kirschning A. Molekulare Grundlage für die Biosynthese von Elansolid: Beweise für eine einzigartige, durch ein Chinonmethid initiierte intramolekulare Diels-Alder-Cycloaddition/Makrolactonisierung Angewandte Chemie. 123: 3968-3973. DOI: 10.1002/Ange.201006880  0.446
2011 Steinmetz H, Gerth K, Jansen R, Schläger N, Dehn R, Reinecke S, Kirschning A, Müller R. Elansolid A, ein einzigartiges Antibiotikum aus Chitinophaga sancti: isoliert in Form von zwei stabilen Atropisomeren† Angewandte Chemie. 123: 553-557. DOI: 10.1002/Ange.201005226  0.375
2010 Harmrolfs K, Brünjes M, Dräger G, Floss HG, Sasse F, Taft F, Kirschning A. Cyclization of synthetic seco-proansamitocins to ansamitocin macrolactams by Actinosynnema pretiosum as biocatalyst. Chembiochem : a European Journal of Chemical Biology. 11: 2517-20. PMID 21077088 DOI: 10.1002/Cbic.201000422  0.579
2010 Su Y, Kasper C, Kirschning A, Dräger G, Berski S. Synthesis of new polysialic acid derivatives Macromolecular Bioscience. 10: 1028-1033. PMID 20602419 DOI: 10.1002/Mabi.201000094  0.337
2010 Ceylan S, Klande T, Vogt C, Friese C, Kirschning A. Chemical synthesis with inductively heated copper flow reactors Synlett. 2009-2013. DOI: 10.1055/S-0030-1258487  0.323
2010 Yusubov MS, Yusubova RY, Funk TV, Chi KW, Kirschning A, Zhdankin VV. M-iodosylbenzoic acid as a convenient recyclable hypervalent iodine oxidant for the synthesis of α-iodo ketones by oxidative iodination of ketones Synthesis. 3681-3685. DOI: 10.1055/S-0030-1258223  0.332
2010 Vogt M, Ceylan S, Kirschning A. Stereocontrolled palladium-catalysed umpolung allylation of aldehydes with allyl acetates Tetrahedron. 66: 6450-6456. DOI: 10.1016/J.Tet.2010.04.133  0.357
2010 Jansen R, Irschik H, Huch V, Schummer D, Steinmetz H, Bock M, Schmidt T, Kirschning A, Müller R. Carolacton - A macrolide ketocarbonic acid that reduces biofilm formation by the caries- and endocarditis-associated bacterium Streptococcus mutans European Journal of Organic Chemistry. 1284-1289. DOI: 10.1002/Ejoc.200901126  0.426
2009 Eichner S, Floss HG, Sasse F, Kirschning A. New, highly active nonbenzoquinone geldanamycin derivatives by using mutasynthesis. Chembiochem : a European Journal of Chemical Biology. 10: 1801-5. PMID 19554593 DOI: 10.1002/Cbic.200900246  0.503
2009 Gallier F, Hussain H, Martel A, Kirschning A, Dujardin G. Hetero-Diels-Alder reactions of cyclic ketone derived enamide. A new and efficient concept for the asymmetric Robinson annulation. Organic Letters. 11: 3060-3. PMID 19537770 DOI: 10.1021/Ol901065E  0.373
2009 Taft F, Brünjes M, Knobloch T, Floss HG, Kirschning A. Timing of the Delta(10,12)-Delta(11,13) double bond migration during ansamitocin biosynthesis in Actinosynnema pretiosum. Journal of the American Chemical Society. 131: 3812-3. PMID 19292483 DOI: 10.1021/Ja8088923  0.476
2009 Yusubov MS, Funk TV, Yusubova RY, Zholobova G, Kirschning A, Park JY, Chi KW. M-iodosylbenzoic acid: Recyclable hypervalent iodine reagent for-tosyloxylation and-mesyloxylation of ketones Synthetic Communications. 39: 3772-3784. DOI: 10.1080/00397910902838870  0.321
2009 Kirschning A, Luiken S, Migliorini A, Loreto MA, Vogt M. Studies on the 1,2-brook rearrangement of bissilyl ketones Synlett. 429-432. DOI: 10.1055/S-0028-1087535  0.356
2008 Berski S, van Bergeijk J, Schwarzer D, Stark Y, Kasper C, Scheper T, Grothe C, Gerardy-Schahn R, Kirschning A, Dräger G. Synthesis and biological evaluation of a polysialic acid-based hydrogel as enzymatically degradable scaffold material for tissue engineering Biomacromolecules. 9: 2353-2359. PMID 18690740 DOI: 10.1021/Bm800327S  0.307
2008 Oelze B, Albert D, Kirschning A. Synthetic and structural studies on macrocyclic amino cyclitols - Conformational chameleons Organic and Biomolecular Chemistry. 6: 2412-2425. PMID 18563277 DOI: 10.1039/B716347A  0.313
2008 Busch T, Kirschning A. Recent advances in the total synthesis of pharmaceutically relevant diterpenes. Natural Product Reports. 25: 318-41. PMID 18389140 DOI: 10.1039/B705652B  0.328
2008 Taft F, Brünjes M, Floss HG, Czempinski N, Grond S, Sasse F, Kirschning A. Highly active ansamitocin derivatives: mutasynthesis using an AHBA-blocked mutant. Chembiochem : a European Journal of Chemical Biology. 9: 1057-60. PMID 18381586 DOI: 10.1002/Cbic.200700742  0.486
2008 Hartlieb S, Günzel A, Gerardy-Schahn R, Münster-Kühnel AK, Kirschning A, Dräger G. Chemoenzymatic synthesis of CMP-N-acetyl-7-fluoro-7-deoxy-neuraminic acid Carbohydrate Research. 343: 2075-2082. PMID 18353292 DOI: 10.1016/J.Carres.2008.02.003  0.355
2008 Kunst E, Gallier F, Dujardin G, Kirschning A. Glycosidations of 2-deoxy glycosyl dithiophosphates using a tagged iodine(iii)-promoter for simple purification Organic and Biomolecular Chemistry. 6: 893-898. PMID 18292881 DOI: 10.1039/B718642H  0.309
2008 Bock M, Buntin K, Müller R, Kirschning A. Stereochemical determination of thuggacins A-C, highly active antibiotics from the myxobacterium Sorangium cellulosum. Angewandte Chemie (International Ed. in English). 47: 2308-11. PMID 18275054 DOI: 10.1002/Anie.200704897  0.406
2008 Luiken S, Kirschning A. Polymer-assisted dithane hydrolysis with minimum workup. The Journal of Organic Chemistry. 73: 2018-20. PMID 18271599 DOI: 10.1021/Jo7025146  0.31
2008 Yusubov MS, Funk TV, Chi KW, Cha EH, Kim GH, Kirschning A, Zhdankin VV. Preparation and X-ray structures of 3-[Bis(trifluoroacetoxy)iodo]benzoic acid and 3-[hydroxy(tosyloxy)iodo]benzoic acid: new recyclable hypervalent iodine reagents. The Journal of Organic Chemistry. 73: 295-7. PMID 18062703 DOI: 10.1021/Jo702112S  0.324
2008 Kirschning A, Gułajski L, Mennecke K, Meyer A, Busch T, Grela K. Highly active ammonium-tagged olefin-metathesis catalyst for simplified purification Synlett. 2692-2696. DOI: 10.1055/S-0028-1083512  0.303
2008 Busch T, Schuster H, Kirschning A. Determination of the absolute configuration of the diterpene tonantzitlolone B Tetrahedron Letters. 49: 5273-5275. DOI: 10.1016/J.Tetlet.2008.06.105  0.321
2008 Ceylan S, Friese C, Lammel C, Mazac K, Kirschning A. Induktives Heizen in der organischen Synthese durch Verwendung funktionalisierter magnetischer Nanopartikel in Mikroreaktoren Angewandte Chemie. 120: 9083-9086. DOI: 10.1002/Ange.200801474  0.335
2008 Bock M, Buntin K, Müller R, Kirschning A. Bestimmung der relativen und absoluten Konfiguration von Thuggacin A–C, hochaktiven Antibiotika aus dem Myxobakterium Sorangium cellulosum Angewandte Chemie. 120: 2341-2344. DOI: 10.1002/Ange.200704897  0.368
2007 Kunst E, Gallier F, Dujardin G, Yusubov MS, Kirschning A. Tagged hypervalent iodine reagents: a new purification concept based on ion exchange through SN2 substitution. Organic Letters. 9: 5199-202. PMID 17999512 DOI: 10.1021/Ol702319P  0.312
2007 Dräger G, Kiss C, Kunz U, Kirschning A. Enzyme-purification and catalytic transformations in a microstructured PASSflow reactor using a new tyrosine-based Ni-NTA linker system attached to a polyvinylpyrrolidinone-based matrix. Organic & Biomolecular Chemistry. 5: 3657-64. PMID 17971995 DOI: 10.1039/B712804E  0.307
2007 Clavier H, Grela K, Kirschning A, Mauduit M, Nolan SP. Sustainable concepts in olefin metathesis. Angewandte Chemie (International Ed. in English). 46: 6786-801. PMID 17640026 DOI: 10.1002/Anie.200605099  0.307
2007 Jöge T, Jesberger M, Bröker P, Kirschning A. Synthetic access to spacer-linked 3,6-diamino-2,3,6-trideoxy-alpha-D-glucopyranosides--potential aminoglycoside mimics for the inhibition of the HIV-1 TAR-RNA/Tat-peptide complex. Carbohydrate Research. 342: 1704-14. PMID 17562328 DOI: 10.1016/J.Carres.2007.05.015  0.307
2007 Meyer A, Brünjes M, Taft F, Frenzel T, Sasse F, Kirschning A. Chemoenzymatic approaches toward dechloroansamitocin P-3. Organic Letters. 9: 1489-92. PMID 17378571 DOI: 10.1021/Ol0702270  0.327
2007 Dawood KM, Solodenko W, Kirschning A. Microwave-accelerated Mizoroki-Heck and Sonogashira cross- coupling reactions in water using a heterogeneous palladium(II)-precatalyst Arkivoc. 2007: 104-124. DOI: 10.3998/Ark.5550190.0008.510  0.309
2007 Meyer A, Kirschning A. Total syntheses of new proansamitocin derivatives by ring-closing metathesis Synlett. 1264-1268. DOI: 10.1055/S-2007-977441  0.373
2007 Schaumann E, Kirschning A. Domino synthesis of carbo- and heterocycles involving a 1,3 or 1,4 C→O silyl migration Synlett. 177-190. DOI: 10.1055/S-2007-968023  0.57
2007 Solodenko W, Jas G, Kunz U, Kirschning A. Continuous enantioselective kinetic resolution of terminal epoxides using immobilized chiral cobalt-salen complexes Synthesis. 583-589. DOI: 10.1055/S-2007-965877  0.312
2007 Kashin D, Meyer A, Wittenberg R, Schöning KU, Kamlage S, Kirschning A. A practical synthesis of the ansa chain of benzenic ansamycin antibiotics: Total synthesis of an ansatrienol derivative Synthesis. 304-319. DOI: 10.1055/S-2006-958967  0.394
2007 Kirschning A, Kujat C, Luiken S, Schaumann E. Small and versatile - Formyl anion and dianion equivalents European Journal of Organic Chemistry. 2387-2400. DOI: 10.1002/Ejoc.200601003  0.589
2006 Michrowska A, Mennecke K, Kunz U, Kirschning A, Grela K. A new concept for the noncovalent binding of a ruthenium-based olefin metathesis catalyst to polymeric phases: preparation of a catalyst on Raschig rings. Journal of the American Chemical Society. 128: 13261-7. PMID 17017807 DOI: 10.1021/Ja063561K  0.326
2006 Jasper C, Adibekian A, Busch T, Quitschalle M, Wittenberg R, Kirschning A. Total synthesis of cyclic diterpene tonantzitlolone based on a highly stereoselective substrate-controlled aldol reaction and ring-closing metathesis. Chemistry (Weinheim An Der Bergstrasse, Germany). 12: 8719-34. PMID 16955524 DOI: 10.1002/Chem.200600082  0.374
2006 Kubota T, Brünjes M, Frenzel T, Xu J, Kirschning A, Floss HG. Determination of the cryptic stereochemistry of the first PKS chain-extension step in ansamitocin biosynthesis by Actinosynnema pretiosum. Chembiochem : a European Journal of Chemical Biology. 7: 1221-5. PMID 16927319 DOI: 10.1002/Cbic.200500506  0.528
2006 Frenzel T, Brünjes M, Quitschalle M, Kirschning A. Synthesis of the N-acetylcysteamine thioester of seco-proansamitocin. Organic Letters. 8: 135-8. PMID 16381586 DOI: 10.1021/Ol052588Q  0.359
2006 Kunst E, Kirschning A. Total synthesis of the trisaccharide unit of the molecular chaperone down-regulator versipelostatin Synthesis. 2397-2403. DOI: 10.1055/S-2006-942450  0.332
2006 Solodenko W, Bröker P, Messinger J, Schön U, Kirschning A. Synthesis of Unprotected Guanidines Using Polymer-Bound Pyrazole Derivatives Synfacts. 2006: 397-397. DOI: 10.1055/S-2006-932086  0.307
2006 Mennecke K, Grela K, Kunz U, Kirschning A. Immobilisation of the Grubbs III Olefin Metathesis Catalyst with Polyvinyl Pyridine (PVP). Cheminform. 37. DOI: 10.1055/S-2005-918958  0.319
2006 Michrowska A, Gułajski Ł, Kaczmarska Z, Mennecke K, Kirschning A, Grela K. A green catalyst for green chemistry: Synthesis and application of an olefin metathesis catalyst bearing a quaternary ammonium group Green Chemistry. 8: 685-688. DOI: 10.1039/B605138C  0.314
2005 Jasper C, Wittenberg R, Quitschalle M, Jakupovic J, Kirschning A. Total synthesis and elucidation of the absolute configuration of the diterpene tonantzitlolone. Organic Letters. 7: 479-82. PMID 15673269 DOI: 10.1021/Ol047559E  0.377
2005 Kunz U, Kirschning A, Wen HL, Solodenko W, Cecilia R, Kappe CO, Turek T. Monolithic polymer/carrier materials: Versatile composites for fine chemical synthesis Catalysis Today. 105: 318-324. DOI: 10.1016/J.Cattod.2005.06.046  0.305
2004 Jaunzems J, Oelze B, Kirschning A. Preparation of macrocyclic 15N-labelled oligoaminodeoxysaccharides as probes for RNA-binding. Organic & Biomolecular Chemistry. 2: 3448-56. PMID 15565236 DOI: 10.1039/B412436G  0.318
2004 Wittenberg R, Beier C, Dräger G, Jas G, Jasper C, Monenschein H, Kirschning A. Towards the total synthesis of tonantzitlolone - Preparation of key fragments and the complete carbon backbone Tetrahedron Letters. 45: 4457-4460. DOI: 10.1016/J.Tetlet.2004.04.056  0.376
2004 Kirschning A, Chen GW, Jaunzems J, Jesberger M, Kalesse M, Lindner M. Synthesis of extended spacer-linked neooligodeoxysaccharides by metathesis olefination and evaluation of their RNA-binding properties Tetrahedron. 60: 3505-3521. DOI: 10.1016/J.Tet.2004.02.013  0.347
2004 Solodenko W, Wen H, Leue S, Stuhlmann F, Sourkouni-Argirusi G, Jas G, Schönfeld H, Kunz U, Kirschning A. Development of a continuous-flow system for catalysis with palladium(0) particles European Journal of Organic Chemistry. 3601-3610. DOI: 10.1002/Ejoc.200400194  0.33
2004 Jaunzems J, Kashin D, Schönberger A, Kirschning A. Polymer-bound diphenylphosphane hydrobromide, a mild acid for the activation of enol ethers: Applications in polymer-assisted glycosidations European Journal of Organic Chemistry. 3435-3446. DOI: 10.1002/Ejoc.200400069  0.321
2003 Kunz U, Schönfeld H, Kirschning A, Solodenko W. Polymer/carrier composites as materials and reactors for organic synthesis. Journal of Chromatography. A. 1006: 241-9. PMID 12938889 DOI: 10.1016/S0021-9673(03)00556-9  0.304
2003 Kirschning A, Kunst E, Ries M, Rose L, Schönberger A, Wartchow R. Polymer-bound haloate(I) anions by iodine(III)-mediated oxidation ofpolymer-bound iodide: Synthetic utility in natural product transformations Arkivoc. 2003: 145-163. DOI: 10.3998/Ark.5550190.0004.617  0.327
2002 Chen GW, Kirschning A. First preparation of spacer-linked cyclic neooligoaminodeoxysaccharides. Chemistry (Weinheim An Der Bergstrasse, Germany). 8: 2717-29. PMID 12391650 DOI: 10.1002/1521-3765(20020617)8:12<2717::Aid-Chem2717>3.0.Co;2-P  0.361
2002 Monenschein H, Brünjes M, Kirschning A. Lithiated dimethoxymethyl diphenyl phosphine oxide, a versatile formiate carbanion equivalent Synlett. 525-527. DOI: 10.1055/S-2002-20486  0.301
2002 Dräger G, Solodenko W, Messinger J, Schön U, Kirschning A. A new reagent and its polymer-supported variant for the amidination of amines Tetrahedron Letters. 43: 1401-1403. DOI: 10.1016/S0040-4039(01)02403-0  0.364
2001 Kirschning A, Jesberger M, Schönberger A. The first polymer-assisted solution-phase synthesis of deoxyglycosides. Organic Letters. 3: 3623-6. PMID 11700097 DOI: 10.1021/Ol016545V  0.312
2001 Kirschning A, Monenschein H, Wittenberg R. Functionalized Polymers-Emerging Versatile Tools for Solution-Phase Chemistry and Automated Parallel Synthesis. Angewandte Chemie (International Ed. in English). 40: 650-679. PMID 11241594 DOI: 10.1002/1521-3773(20010216)40:4<650::Aid-Anie6500>3.0.Co;2-C  0.323
2001 Kirschning A, Jesberger M, Schöning KU. Concepts for the total synthesis of deoxy sugars Synthesis. 507-540. DOI: 10.1055/S-2001-12342  0.358
2000 Kirschning A, Monenschein H, Wittenberg R. The "resin-capture-release" hybrid technique: a merger between solid- and solution-phase synthesis. Chemistry (Weinheim An Der Bergstrasse, Germany). 6: 4445-50. PMID 11192076 DOI: 10.1002/1521-3765(20001215)6:24<4445::Aid-Chem4445>3.0.Co;2-W  0.314
2000 Kirschning A, Chen GW, Dräger G, Schuberth I, Tietze LF. Syntheses and biological evaluation of new glyco-modified angucyclin-antibiotics. Bioorganic & Medicinal Chemistry. 8: 2347-54. PMID 11026547 DOI: 10.1016/S0968-0896(00)00166-8  0.346
2000 Kirschning A, Chen GW. Synthesis of spacer-linked tail to tail dimers derived from a conformationally rigid aminodeoxysugar by olefin metathesis Synthesis. 1133-1137. DOI: 10.1055/S-2000-6328  0.368
1999 Monenschein H, Sourkouni-Argirusi G, Schubothe KM, O'Hare T, Kirschning A. Reactions of alkenes, alkynes, and alkoxyallenes with new polymer-supported electrophilic reagents Organic Letters. 1: 2101-2104. DOI: 10.1021/Ol991149M  0.357
1999 Lee S, Kirschning A, Müller M, Way C, Floss HG. Enzymatic synthesis of [7-14C, 7-3H]- and [1-13C]sedoheptulose 7- phosphate and [1-13C]ido-heptulose 7-phosphate Journal of Molecular Catalysis - B Enzymatic. 6: 369-377. DOI: 10.1016/S1381-1177(98)00131-3  0.492
1999 Schöning KU, Hayashi RK, Powell DR, Kirschning A. Synthetic studies toward ansatrienines: Application of the Evans- Tishchenko reaction to chiral enones Tetrahedron Asymmetry. 10: 817-820. DOI: 10.1016/S0957-4166(99)00069-5  0.355
1999 Kirschning A, Jesberger M, Monenschein H. Application of polymer-supported electrophilic reagents for the 1,2-functionalization of glycals Tetrahedron Letters. 40: 8999-9002. DOI: 10.1016/S0040-4039(99)01925-5  0.337
1999 Kirschning A, Chen GW. Syntheses of spacer-linked neodisaccharides derived from L-Daunosamine Tetrahedron Letters. 40: 4665-4668. DOI: 10.1016/S0040-4039(99)00862-X  0.347
1999 Monenschein H, Dräger G, Jung A, Kirschning A. Asymmetric nucleophilic acylation of aldehydes via 1,1-heterodisubstituted alkenes Chemistry - a European Journal. 5: 2270-2280. DOI: 10.1002/(Sici)1521-3765(19990802)5:8<2270::Aid-Chem2270>3.0.Co;2-L  0.365
1998 Kirschning A, Plumeier C, Rose L. Phosphonium salts of diacetoxyiodine(I) anions, new reagents for the iodoacetoxylation of alkenes Chemical Communications. 33-34. DOI: 10.1039/A706305I  0.325
1998 Bräuer N, Kirschning A, Schaumann E. A Silicon‐Mediated Synthesis of 3‐Deoxy‐D‐manno‐octulosonic Acid (KDO) European Journal of Organic Chemistry. 1998: 2729-2732. DOI: 10.1002/(Sici)1099-0690(199812)1998:12<2729::Aid-Ejoc2729>3.0.Co;2-F  0.54
1998 Kirschning A. Hypervalent Iodine And Carbohydrates : A New Liaison European Journal of Organic Chemistry. 1998: 2267-2274. DOI: 10.1002/(Sici)1099-0690(199811)1998:11<2267::Aid-Ejoc2267>3.0.Co;2-E  0.355
1997 Kirschning A, Ries M, Domann S, Martin W, Albrecht W, Arnold P, Laufer S. Synthesis and biological identification of the acyl glucuronide of the antiinflammatory drug ML-3000 Bioorganic & Medicinal Chemistry Letters. 7: 903-906. DOI: 10.1016/S0960-894X(97)00123-6  0.319
1997 Kirschning A, Harders J. Addition of C-nucleophiles to carbohydrate-derived 2,3-dihydro-4H-pyran-4-ones: A new entry to thromboxane analogues Tetrahedron. 53: 7867-7876. DOI: 10.1016/S0040-4020(97)00475-4  0.316
1997 Kirschning A, Bechthold AFW, Rohr J. Chemical and biochemical aspects of deoxysugars and deoxysugar oligosaccharides Topics in Current Chemistry. 188: 1-84. DOI: 10.1007/Bfb0119234  0.307
1997 Kirschning A, Dräger G, Jung A. A New Asymmetric Formylation of Aldehydes Angewandte Chemie. 36: 253-255. DOI: 10.1002/Anie.199702531  0.305
1996 Kim CG, Kirschning A, Bergon P, Zhou P, Su E, Sauerbrei B, Ning S, Ahn Y, Breuer M, Leistner E, Floss HG. Biosynthesis of 3-amino-5-hydroxybenzoic acid, the precursor of mC7N units in ansamycin antibiotics Journal of the American Chemical Society. 118: 7486-4791. DOI: 10.1021/Ja9601292  0.511
1996 Michel T, Kirschning A, Beier C, Bräuer N, Schaumann E, Adiwidjaja G. Synthesis Of Functionalized Cyclopentanes, Cyclohexanes And Cycloheptanes By A Silicon-Induced Domino Reaction Liebigs Annalen. 1996: 1811-1821. DOI: 10.1002/Jlac.199619961115  0.55
1995 Adiwidjaja G, Flörke H, Kirschning A, Schaumann E. Cyclizations of 5-silyl-substituted 4,5-epoxy-1-alkanols: A configuration dependent mode of ring closure Tetrahedron Letters. 36: 8771-8774. DOI: 10.1016/0040-4039(95)01915-5  0.542
1995 Kirschning A. 3,4‐bis(O‐tert‐butyldimethylsilyl)‐6‐O‐tosyl‐D‐glucal: A probe for the mechanism of the iodine(III)‐promoted allylic oxidation of glycals Liebigs Annalen. 1995: 2053-2056. DOI: 10.1002/Jlac.1995199511289  0.311
1995 Adiwidjaja G, Flörke H, Kirschning A, Schauman E. Electrophile-Induced Cyclizations Of Silyl-Substituted 4-Alken-1-Ols Liebigs Annalen. 1995: 501-507. DOI: 10.1002/Jlac.199519950369  0.345
1994 Kirschning A, Bergon P, Wang JJ, Breazeale S, Floss HG. Synthesis of 4-amino 3,4-dideoxy-D-arabino-heptulosonic acid 7-phosphate, the biosynthetic precursor of C7N units in ansamycin antibiotics. Carbohydrate Research. 256: 245-56. PMID 8187101 DOI: 10.1016/0008-6215(94)84211-6  0.53
1994 Fischer M, Kirschning A, Michel T, Schaumann E. Syntheses of Cyclopentanols by a Silicon-Induced Cascade Reaction† Angewandte Chemie. 33: 217-218. DOI: 10.1002/Anie.199402171  0.482
1994 Fischer M, Kirschning A, Michel T, Schaumann E. Cyclopentanole durch eine Silicium‐induzierte Reaktionskaskade Angewandte Chemie. 106: 220-221. DOI: 10.1002/Ange.19941060221  0.459
1992 Kim CG, Kirschning A, Bergon P, Ahn Y, Wang JJ, Shibuya M, Floss HG. Formation of 3-amino-5-hydroxybenzoic acid, the precursor of mC7N units in ansamycin antibiotics, by a new variant of the shikimate pathway Journal of the American Chemical Society. 114: 4941-4943. DOI: 10.1021/Ja00038A090  0.506
1991 Schaumann E, Kirschning A, Narjes F. Synthesis of vinylcyclopropanes from epoxides Journal of Organic Chemistry. 56: 717-723. DOI: 10.1021/Jo00002A043  0.568
1991 Kirschning A, Narjes F, Schaumann E. Synthese von rac-Norartemeseol European Journal of Organic Chemistry. 1991: 933-936. DOI: 10.1002/Jlac.1991199101159  0.567
1990 Schaumann E, Kirschning A. Perkin communications: Iodonium-induced cyclisations of 5-silylalk-4-enols Journal of the Chemical Society, Perkin Transactions 1. 1481-1483. DOI: 10.1039/P19900001481  0.518
1990 Schaumann E, Kirschning A. Regiospecific synthesis of 1-silyl substituted 1,4-dienes Journal of the Chemical Society-Perkin Transactions 1. 419-421. DOI: 10.1039/P19900000419  0.555
1988 Schaumann E, Kirschning A. Ring-opening of oxiranes by silyl-substituted allyl anions. A regiochemical chameleon Tetrahedron Letters. 29: 4281-4284. DOI: 10.1016/S0040-4039(00)80474-8  0.539
Show low-probability matches.