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Stacy Malaker - Publications

Affiliations: 
Yale University, New Haven, CT 
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41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Chongsaritsinsuk J, Steigmeyer AD, Mahoney KE, Rosenfeld MA, Lucas TM, Smith CM, Li A, Ince D, Kearns FL, Battison AS, Hollenhorst MA, Judy Shon D, Tiemeyer KH, Attah V, Kwon C, ... ... Malaker SA, et al. Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE. Nature Communications. 14: 6169. PMID 37794035 DOI: 10.1038/s41467-023-41756-y  0.646
2023 Pedram K, Shon DJ, Tender GS, Mantuano NR, Northey JJ, Metcalf KJ, Wisnovsky SP, Riley NM, Forcina GC, Malaker SA, Kuo A, George BM, Miller CL, Casey KM, Vilches-Moure JG, et al. Design of a mucin-selective protease for targeted degradation of cancer-associated mucins. Nature Biotechnology. PMID 37537499 DOI: 10.1038/s41587-023-01840-6  0.745
2023 Hollander MJ, Malaker SA, Riley NM, Perez I, Abney NM, Gray MA, Maxson JE, Cochran JR, Bertozzi CR. Mutational screens highlight glycosylation as a modulator of colony-stimulating factor 3 receptor (CSF3R) activity. The Journal of Biological Chemistry. 104755. PMID 37116708 DOI: 10.1016/j.jbc.2023.104755  0.698
2023 Gonzalez-Rodriguez E, Zol-Hanlon M, Bineva-Todd G, Marchesi A, Skehel M, Mahoney KE, Roustan C, Borg A, Di Vagno L, Kjær S, Wrobel AG, Benton DJ, Nawrath P, Flitsch SL, Joshi D, ... ... Malaker SA, et al. O-Linked Sialoglycans Modulate the Proteolysis of SARS-CoV-2 Spike and Likely Contribute to the Mutational Trajectory in Variants of Concern. Acs Central Science. 9: 393-404. PMID 36968546 DOI: 10.1021/acscentsci.2c01349  0.591
2023 Boyce M, Malaker SA, Riley NM, Kohler JJ. The 2022 Nobel prize in chemistry - sweet! Glycobiology. PMID 36892406 DOI: 10.1093/glycob/cwad016  0.645
2023 Chongsaritsinsuk J, Steigmeyer AD, Mahoney KE, Rosenfeld MA, Lucas TM, Ince D, Kearns FL, Battison AS, Hollenhorst MA, Shon DJ, Tiemeyer KH, Attah V, Kwon C, Bertozzi CR, Ferracane MJ, ... ... Malaker SA, et al. Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE. Biorxiv : the Preprint Server For Biology. PMID 36778266 DOI: 10.1101/2023.02.01.526488  0.74
2023 Hollenhorst MA, Tiemeyer KH, Mahoney KE, Aoki K, Ishihara M, Lowery SC, Rangel-Angarita V, Bertozzi CR, Malaker SA. Comprehensive analysis of platelet glycoprotein Ibα ectodomain glycosylation. Journal of Thrombosis and Haemostasis : Jth. PMID 36740532 DOI: 10.1016/j.jtha.2023.01.009  0.513
2023 Calle B, Gonzalez-Rodriguez E, Mahoney KE, Cioce A, Bineva-Todd G, Tastan OY, Roustan C, Flynn H, Malaker SA, Schumann B. Bump-and-hole engineering of human polypeptide N-acetylgalactosamine transferases to dissect their protein substrates and glycosylation sites in cells. Star Protocols. 4: 101974. PMID 36633947 DOI: 10.1016/j.xpro.2022.101974  0.578
2022 Cioce A, Calle B, Rizou T, Lowery SC, Bridgeman VL, Mahoney KE, Marchesi A, Bineva-Todd G, Flynn H, Li Z, Tastan OY, Roustan C, Soro-Barrio P, Rafiee MR, Garza-Garcia A, ... ... Malaker SA, et al. Cell-specific bioorthogonal tagging of glycoproteins. Nature Communications. 13: 6237. PMID 36284108 DOI: 10.1038/s41467-022-33854-0  0.728
2022 Medley BJ, Leclaire L, Thompson N, Mahoney KE, Pluvinage B, Parson MAH, Burke JE, Malaker S, Wakarchuk W, Boraston AB. A previously uncharacterized O-glycopeptidase from Akkermansia muciniphila requires the Tn-antigen for cleavage of the peptide bond. The Journal of Biological Chemistry. 102439. PMID 36049519 DOI: 10.1016/j.jbc.2022.102439  0.417
2022 Ince D, Lucas TM, Malaker SA. Current strategies for characterization of mucin-domain glycoproteins. Current Opinion in Chemical Biology. 69: 102174. PMID 35752002 DOI: 10.1016/j.cbpa.2022.102174  0.397
2022 Malaker SA, Riley NM, Shon DJ, Pedram K, Krishnan V, Dorigo O, Bertozzi CR. Revealing the human mucinome. Nature Communications. 13: 3542. PMID 35725833 DOI: 10.1038/s41467-022-31062-4  0.734
2022 Yao Y, Kim G, Shafer S, Chen Z, Kubo S, Ji Y, Luo J, Yang W, Perner SP, Kanellopoulou C, Park AY, Jiang P, Li J, Baris S, Aydiner EK, ... ... Malaker SA, et al. Mucus sialylation determines intestinal host-commensal homeostasis. Cell. PMID 35303419 DOI: 10.1016/j.cell.2022.02.013  0.576
2021 Carroll DJ, Burns MWN, Mottram L, Propheter DC, Boucher A, Lessen GM, Kumar A, Malaker SA, Xing C, Hooper LV, Yrlid U, Kohler JJ. Interleukin-22 regulates B3GNT7 expression to induce fucosylation of glycoproteins in intestinal epithelial cells. The Journal of Biological Chemistry. 101463. PMID 34864058 DOI: 10.1016/j.jbc.2021.101463  0.557
2021 Burt RA, Dejanovic B, Peckham HJ, Lee KA, Li X, Ounadjela JR, Rao A, Malaker SA, Carr SA, Myers SA. Novel antibodies for the simple and efficient enrichment of native O-GlcNAc modified peptides. Molecular & Cellular Proteomics : McP. 100167. PMID 34678516 DOI: 10.1016/j.mcpro.2021.100167  0.374
2021 Penny SA, Abelin JG, Malaker SA, Myers PT, Saeed AZ, Steadman LG, Bai DL, Ward ST, Shabanowitz J, Hunt DF, Cobbold M. Tumor Infiltrating Lymphocytes Target HLA-I Phosphopeptides Derived From Cancer Signaling in Colorectal Cancer. Frontiers in Immunology. 12: 723566. PMID 34504498 DOI: 10.3389/fimmu.2021.723566  0.763
2021 Rangel-Angarita V, Malaker SA. Mucinomics as the Next Frontier of Mass Spectrometry. Acs Chemical Biology. 16: 1866-1883. PMID 34319686 DOI: 10.1021/acschembio.1c00384  0.423
2021 Malaker SA, Quanico J, Raffo-Romero A, Kobeissy F, Aboulouard S, Tierny D, Bertozzi CR, Fournier I, Salzet M. On-tissue spatially resolved glycoproteomics guided by N-glycan imaging reveal global dysregulation of canine glioma glycoproteomic landscape. Cell Chemical Biology. PMID 34102146 DOI: 10.1016/j.chembiol.2021.05.007  0.573
2021 Flynn RA, Pedram K, Malaker SA, Batista PJ, Smith BAH, Johnson AG, George BM, Majzoub K, Villalta PW, Carette JE, Bertozzi CR. Small RNAs are modified with N-glycans and displayed on the surface of living cells. Cell. PMID 34004145 DOI: 10.1016/j.cell.2021.04.023  0.741
2021 Shon DJ, Kuo A, Ferracane MJ, Malaker SA. Classification, structural biology, and applications of mucin domain-targeting proteases. The Biochemical Journal. 478: 1585-1603. PMID 33909028 DOI: 10.1042/BCJ20200607  0.417
2021 Calle B, Bineva-Todd G, Marchesi A, Flynn H, Ghirardello M, Tastan OY, Roustan C, Choi J, Galan MC, Schumann B, Malaker SA. Benefits of Chemical Sugar Modifications Introduced by Click Chemistry for Glycoproteomic Analyses. Journal of the American Society For Mass Spectrometry. PMID 33871988 DOI: 10.1021/jasms.1c00084  0.767
2021 Rumachik NG, Malaker SA, Paulk NK. VectorMOD: Method for Bottom-Up Proteomic Characterization of rAAV Capsid Post-Translational Modifications and Vector Impurities. Frontiers in Immunology. 12: 657795. PMID 33868302 DOI: 10.3389/fimmu.2021.657795  0.329
2021 Wisnovsky S, Möckl L, Malaker SA, Pedram K, Hess GT, Riley NM, Gray MA, Smith BAH, Bassik MC, Moerner WE, Bertozzi CR. Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33495350 DOI: 10.1073/pnas.2015024118  0.752
2020 Cioce A, Malaker SA, Schumann B. Generating orthogonal glycosyltransferase and nucleotide sugar pairs as next-generation glycobiology tools. Current Opinion in Chemical Biology. 60: 66-78. PMID 33125942 DOI: 10.1016/j.cbpa.2020.09.001  0.642
2020 Riley NM, Malaker SA, Bertozzi CR. Electron-Based Dissociation Is Needed for O-Glycopeptides Derived from OpeRATOR Proteolysis. Analytical Chemistry. PMID 33125225 DOI: 10.1021/acs.analchem.0c02950  0.714
2020 Rumachik NG, Malaker SA, Poweleit N, Maynard LH, Adams CM, Leib RD, Cirolia G, Thomas D, Stamnes S, Holt K, Sinn P, May AP, Paulk NK. Methods Matter: Standard Production Platforms for Recombinant AAV Produce Chemically and Functionally Distinct Vectors. Molecular Therapy. Methods & Clinical Development. 18: 98-118. PMID 32995354 DOI: 10.1016/j.omtm.2020.05.018  0.365
2020 Debets MF, Tastan OY, Wisnovsky SP, Malaker SA, Angelis N, Moeckl LKR, Choi J, Flynn H, Wagner LJS, Bineva-Todd G, Antonopoulos A, Cioce A, Browne WM, Li Z, Briggs DC, et al. Metabolic precision labeling enables selective probing of O-linked -acetylgalactosamine glycosylation. Proceedings of the National Academy of Sciences of the United States of America. PMID 32989128 DOI: 10.1073/pnas.2007297117  0.795
2020 Shon DJ, Malaker SA, Pedram K, Yang E, Krishnan V, Dorigo O, Bertozzi CR. An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 32817557 DOI: 10.1073/Pnas.2012196117  0.641
2020 Gray MA, Stanczak MA, Mantuano NR, Xiao H, Pijnenborg JFA, Malaker SA, Miller CL, Weidenbacher PA, Tanzo JT, Ahn G, Woods EC, Läubli H, Bertozzi CR. Targeted glycan degradation potentiates the anticancer immune response in vivo. Nature Chemical Biology. PMID 32807964 DOI: 10.1038/S41589-020-0622-X  0.689
2020 Riley NM, Malaker SA, Driessen MD, Bertozzi CR. Optimal Dissociation Methods Differ for - and -Glycopeptides. Journal of Proteome Research. PMID 32500713 DOI: 10.1021/Acs.Jproteome.0C00218  0.695
2020 Schumann B, Malaker SA, Wisnovsky SP, Debets MF, Agbay AJ, Fernandez D, Wagner LJS, Lin L, Li Z, Choi J, Fox DM, Peh J, Gray MA, Pedram K, Kohler JJ, et al. Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells. Molecular Cell. PMID 32325029 DOI: 10.1016/J.Molcel.2020.03.030  0.779
2020 Malaker SA, Ferracane MJ. Mass Spectrometric Identification and Molecular Modeling of Glycopeptides Presented by MHC Class I and II Processing Pathways. Methods in Molecular Biology (Clifton, N.J.). 2024: 269-285. PMID 31364056 DOI: 10.1007/978-1-4939-9597-4_17  0.39
2020 Penny SA, Malaker SA. Isolation of Major Histocompatibility Complex (MHC)-Associated Peptides by Immunoaffinity Purification. Methods in Molecular Biology (Clifton, N.J.). 2024: 235-243. PMID 31364053 DOI: 10.1007/978-1-4939-9597-4_14  0.375
2019 Choi J, Wagner LJS, Timmermans SBPE, Malaker S, Schumann B, Gray MA, Debets MF, Takashima M, Gehring J, Bertozzi CR. Engineering Orthogonal Polypeptide GalNAc-Transferase and UDP-Sugar Pairs. Journal of the American Chemical Society. PMID 31373799 DOI: 10.1021/Jacs.9B04695  0.775
2019 Malaker SA, Pedram K, Ferracane MJ, Bensing BA, Krishnan V, Pett C, Yu J, Woods EC, Kramer JR, Westerlind U, Dorigo O, Bertozzi CR. The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins. Proceedings of the National Academy of Sciences of the United States of America. PMID 30910957 DOI: 10.1073/Pnas.1813020116  0.737
2017 Pavlos R, McKinnon EJ, Ostrov DA, Peters B, Buus S, Koelle D, Chopra A, Schutte R, Rive C, Redwood A, Restrepo S, Bracey A, Kaever T, Myers P, Speers E, ... Malaker SA, et al. Shared peptide binding of HLA Class I and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk alleles. Scientific Reports. 7: 8653. PMID 28819312 DOI: 10.1038/S41598-017-08876-0  0.513
2017 Sim MJ, Malaker SA, Khan A, Stowell JM, Shabanowitz J, Peterson ME, Rajagopalan S, Hunt DF, Altmann DM, Long EO, Boyton RJ. Canonical and Cross-reactive Binding of NK Cell Inhibitory Receptors to HLA-C Allotypes Is Dictated by Peptides Bound to HLA-C. Frontiers in Immunology. 8: 193. PMID 28352266 DOI: 10.3389/Fimmu.2017.00193  0.489
2017 Bergmann T, Lindvall M, Moore E, Moore E, Sidney J, Miller D, Tallmadge RL, Myers PT, Malaker SA, Shabanowitz J, Osterrieder N, Peters B, Hunt DF, Antczak DF, Sette A. Peptide-binding motifs of two common equine class I MHC molecules in Thoroughbred horses. Immunogenetics. PMID 28315936 DOI: 10.1007/S00251-017-0978-6  0.508
2017 Malaker SA, Penny SA, Steadman LG, Myers PT, Loke J, Raghavan M, Bai DL, Shabanowitz J, Hunt D, Cobbold M. Identification of glycopeptides as post-translationally modified neoantigens in leukemia. Cancer Immunology Research. PMID 28314751 DOI: 10.1158/2326-6066.Cir-16-0280  0.576
2016 Malaker SA, Ferracane MJ, Depontieu FR, Zarling AL, Shabanowitz J, Bai DL, Topalian SL, Engelhard VH, Hunt DF. Identification and Characterization of Complex Glycosylated Peptides Presented by the MHC Class II Processing Pathway in Melanoma. Journal of Proteome Research. PMID 27550523 DOI: 10.1021/Acs.Jproteome.6B00496  0.581
2013 Cobbold M, De La Peña H, Norris A, Polefrone JM, Qian J, English AM, Cummings KL, Penny S, Turner JE, Cottine J, Abelin JG, Malaker SA, Zarling AL, Huang HW, Goodyear O, et al. MHC class I-associated phosphopeptides are the targets of memory-like immunity in leukemia. Science Translational Medicine. 5: 203ra125. PMID 24048523 DOI: 10.1126/Scitranslmed.3006061  0.661
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