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Neil Warner - Publications

Affiliations: 
Hospital for Sick Children, Toronto, ON 
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Dirvanskyte P, Gurram B, Bolton C, Warner N, Jones KDJ, Griffin HR, Park JY, Keller KM, Gilmour KC, Hambleton S, Muise AM, Wysocki C, Uhlig HH. Chromosomal numeric aberrations and rare copy number variation in patients with inflammatory bowel disease. Journal of Crohn's & Colitis. PMID 35907265 DOI: 10.1093/ecco-jcc/jjac103  0.639
2022 Penon-Portmann M, Westbury SK, Li L, Pluthero FG, Liu RJY, Yao HHY, Geng RSQ, Warner N, Muise AM, Lotz-Esquivel S, Howell-Ramirez M, Saborío-Chacon P, Fernández-Rojas S, Saborio-Rocafort M, Jiménez-Hernández M, et al. Platelet VPS16B is dependent on VPS33B expression, as determined in two siblings with arthrogryposis, renal dysfunction, and cholestasis syndrome. Journal of Thrombosis and Haemostasis : Jth. PMID 35325493 DOI: 10.1111/jth.15711  0.541
2022 Yao Y, Kim G, Shafer S, Chen Z, Kubo S, Ji Y, Luo J, Yang W, Perner SP, Kanellopoulou C, Park AY, Jiang P, Li J, Baris S, Aydiner EK, ... ... Warner N, et al. Mucus sialylation determines intestinal host-commensal homeostasis. Cell. PMID 35303419 DOI: 10.1016/j.cell.2022.02.013  0.655
2022 Sandy NS, Huysentruyt K, Mulder DJ, Warner N, Chong K, Morel C, AlQahtani S, Wales PW, Martin MG, Muise A, Avitzur Y. The Diverse Phenotype of Intestinal Dysmotility Secondary to ACTG2-Related Disorders. Journal of Pediatric Gastroenterology and Nutrition. PMID 35149643 DOI: 10.1097/MPG.0000000000003400  0.612
2022 Wang L, Aschenbrenner D, Zeng Z, Cao X, Mayr D, Mehta M, Capitani M, Warner N, Pan J, Wang L, Li Q, Zuo T, Cohen-Kedar S, Lu J, Ardy RC, et al. Author Correction: Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice. Nature Genetics. PMID 34987219 DOI: 10.1038/s41588-021-00998-6  0.57
2021 Strigli A, Gopalakrishnan S, Zeissig Y, Basic M, Wang J, Schwerd T, Doms S, Peuker K, Hartwig J, Harder J, Hönscheid P, Arnold P, Kurth T, Rost F, Petersen BS, ... ... Warner N, et al. Deficiency in X-linked inhibitor of apoptosis protein promotes susceptibility to microbial triggers of intestinal inflammation. Science Immunology. 6: eabf7473. PMID 34739342 DOI: 10.1126/sciimmunol.abf7473  0.572
2021 Malik A, Stringer E, Warner N, van Limbergen J, Vandersteen A, Muise A, Derfalvi B. Multisystem Autoimmune Inflammatory Disease, Including Colitis, Due to Inborn Error of Immunity. Pediatrics. 148. PMID 34686572 DOI: 10.1542/peds.2021-050614  0.68
2021 Tyler PM, Bucklin ML, Zhao M, Maher TJ, Rice AJ, Ji W, Warner N, Pan J, Morotti R, McCarthy P, Griffiths A, van Rossum AMC, Hollink IHIM, Dalm VASH, Catanzaro J, et al. Human autoinflammatory disease reveals ELF4 as a transcriptional regulator of inflammation. Nature Immunology. PMID 34326534 DOI: 10.1038/s41590-021-00984-4  0.675
2021 Ouahed J, Kelsen JR, Spessott WA, Kooshesh K, Sanmillan ML, Dawany N, Sullivan KE, Hamilton K, Slowik V, Nejentsev S, Neves JF, Flores H, Chung WK, Wilson A, Yeboa KA, ... ... Warner N, et al. Variants in STXBP3 Are Associated With Very Early Onset Inflammatory Bowel Disease, Bilateral Sensorineural Hearing Loss and Immune Dysregulation. Journal of Crohn's & Colitis. PMID 33891011 DOI: 10.1093/ecco-jcc/jjab077  0.686
2021 Wang L, Aschenbrenner D, Zeng Z, Cao X, Mayr D, Mehta M, Capitani M, Warner N, Pan J, Wang L, Li Q, Zuo T, Cohen-Kedar S, Lu J, Ardy RC, et al. Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice. Nature Genetics. PMID 33782605 DOI: 10.1038/s41588-021-00803-4  0.654
2021 Nambu R, Warner N, Mulder DJ, Kotlarz D, McGovern DP, Cho J, Klein C, Snapper SB, Griffiths AM, Iwama I, Muise AM. A Systematic Review of Monogenic Inflammatory Bowel Disease. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 33746097 DOI: 10.1016/j.cgh.2021.03.021  0.625
2021 Bosa L, Batura V, Colavito D, Fiedler K, Gaio P, Guo C, Li Q, Marzollo A, Mescoli C, Nambu R, Pan J, Perilongo G, Warner N, Zhang S, Kotlarz D, et al. Novel CARMIL2 loss-of-function variants are associated with pediatric inflammatory bowel disease. Scientific Reports. 11: 5945. PMID 33723309 DOI: 10.1038/s41598-021-85399-9  0.685
2021 Horowitz JE, Warner N, Staples J, Crowley E, Gosalia N, Murchie R, Van Hout C, Fiedler K, Welch G, King AK, Reid JG, Overton JD, Baras A, Shuldiner AR, Griffiths A, et al. Mutation spectrum of NOD2 reveals recessive inheritance as a main driver of Early Onset Crohn's Disease. Scientific Reports. 11: 5595. PMID 33692434 DOI: 10.1038/s41598-021-84938-8  0.659
2020 Mulder DJ, Khalouei S, Warner N, Gonzaga-Jauregui C, Church PC, Walters TD, Ramani AK, Griffiths AM, Cohn I, Muise AM. Utilization of Whole Exome Sequencing Data to Identify Clinically Relevant Pharmacogenomic Variants in Pediatric Inflammatory Bowel Disease. Clinical and Translational Gastroenterology. 11: e00263. PMID 33512800 DOI: 10.14309/ctg.0000000000000263  0.653
2020 Dhingani N, Guo C, Pan J, Li Q, Warner N, Jardine S, Leung G, Kotlarz D, Gonzaga-Jauregui C, Klein C, Snapper SB, Navas-López VM, Muise AM. The E3 ubiquitin ligase UBR5 interacts with TTC7A and may be associated with very early onset inflammatory bowel disease. Scientific Reports. 10: 18648. PMID 33122718 DOI: 10.1038/s41598-020-73482-6  0.678
2020 Crowley E, Warner N, Pan J, Khalouei S, Elkadri A, Fiedler K, Foong J, Turinsky AL, Bronte-Tinkew D, Zhang S, Hu J, Tian D, Li D, Horowitz J, et al. Prevalence and Clinical Features of Inflammatory Bowel Diseases Associated with Monogenic Variants, Identified by Whole-exome Sequencing in 1000 Children at a Single Center. Gastroenterology. PMID 32084423 DOI: 10.1053/J.Gastro.2020.02.023  0.647
2019 Jardine S, Anderson S, Babcock S, Leung G, Pan J, Dhingani N, Warner N, Guo C, Siddiqui I, Kotlarz D, Dowling JJ, Melnyk R, Snapper SB, Klein C, Thiagarajah JR, et al. Drug Screen Identifies Leflunomide for Treatment of Inflammatory Bowel Diseases Caused by TTC7A Deficiency. Gastroenterology. PMID 31743734 DOI: 10.1053/j.gastro.2019.11.019  0.662
2019 Lu Y, Zheng Y, Coyaud É, Zhang C, Selvabaskaran A, Yu Y, Xu Z, Weng X, Chen JS, Meng Y, Warner N, Cheng X, Liu Y, Yao B, Hu H, et al. Palmitoylation of NOD1 and NOD2 is required for bacterial sensing. Science (New York, N.Y.). 366: 460-467. PMID 31649195 DOI: 10.1126/Science.Aau6391  0.625
2019 Gupta A, Sanville J, Menz T, Warner N, Muise AM, Fiedler K, Martín MG, Padbury J, Phornphutkul C, Sanchez-Esteban J, Cerezo CS. Application of Whole Exome Sequencing in Congenital Secretory Diarrhea Diagnosis. Journal of Pediatric Gastroenterology and Nutrition. PMID 30633106 DOI: 10.1097/Mpg.0000000000002258  0.517
2018 Li Y, Führer M, Bahrami E, Socha P, Klaudel-Dreszler M, Bouzidi A, Liu Y, Lehle AS, Magg T, Hollizeck S, Rohlfs M, Conca R, Field M, Warner N, Mordechai S, et al. Human RIPK1 deficiency causes combined immunodeficiency and inflammatory bowel diseases. Proceedings of the National Academy of Sciences of the United States of America. PMID 30591564 DOI: 10.1073/pnas.1813582116  0.692
2018 Lehle AS, Farin HF, Marquardt B, Michels BE, Magg T, Li Y, Liu Y, Ghalandary M, Lammens K, Hollizeck S, Rohlfs M, Hauck F, Conca R, Walz C, Weiss B, ... ... Warner N, et al. Intestinal Inflammation and Dysregulated Immunity in Patients with Inherited Caspase-8 Deficiency. Gastroenterology. PMID 30267714 DOI: 10.1053/J.Gastro.2018.09.041  0.657
2018 van de Geer A, Nieto-Patlán A, Kuhns DB, Tool AT, Arias AA, Bouaziz M, de Boer M, Franco JL, Gazendam RP, van Hamme JL, van Houdt M, van Leeuwen K, Verkuijlen PJ, van den Berg TK, Alzate JF, ... ... Warner N, et al. Inherited p40phox deficiency differs from classic chronic granulomatous disease. The Journal of Clinical Investigation. PMID 29969437 DOI: 10.1172/Jci97116  0.604
2018 Parlato M, Charbit-Henrion F, Pan J, Romano C, Duclaux-Loras R, Le Du MH, Warner N, Francalanci P, Bruneau J, Bras M, Zarhrate M, Bègue B, Guegan N, Rakotobe S, Kapel N, et al. Human ALPI deficiency causes inflammatory bowel disease and highlights a key mechanism of gut homeostasis. Embo Molecular Medicine. PMID 29567797 DOI: 10.15252/emmm.201708483  0.699
2017 Kahr WH, Pluthero FG, Elkadri A, Warner N, Drobac M, Chen CH, Lo RW, Li L, Li R, Li Q, Thoeni C, Pan J, Leung G, Lara-Corrales I, Murchie R, et al. Loss of the Arp2/3 complex component ARPC1B causes platelet abnormalities and predisposes to inflammatory disease. Nature Communications. 8: 14816. PMID 28368018 DOI: 10.1038/Ncomms14816  0.615
2015 Janecke AR, Heinz-Erian P, Yin J, Petersen BS, Franke A, Lechner S, Fuchs I, Melancon S, Uhlig HH, Travis S, Marinier E, Perisic V, Ristic N, Gerner P, Booth IW, ... ... Warner N, et al. Reduced sodium/proton exchanger NHE3 activity causes congenital sodium diarrhea. Human Molecular Genetics. PMID 26358773 DOI: 10.1093/Hmg/Ddv367  0.621
2014 Caruso R, Warner N, Inohara N, Núñez G. NOD1 and NOD2: signaling, host defense, and inflammatory disease. Immunity. 41: 898-908. PMID 25526305 DOI: 10.1016/J.Immuni.2014.12.010  0.366
2014 Warner N, Burberry A, Pliakas M, McDonald C, Núñez G. A genome-wide small interfering RNA (siRNA) screen reveals nuclear factor-κB (NF-κB)-independent regulators of NOD2-induced interleukin-8 (IL-8) secretion. The Journal of Biological Chemistry. 289: 28213-24. PMID 25170077 DOI: 10.1074/Jbc.M114.574756  0.517
2013 Warner N, Burberry A, Franchi L, Kim YG, McDonald C, Sartor MA, Núñez G. A genome-wide siRNA screen reveals positive and negative regulators of the NOD2 and NF-κB signaling pathways. Science Signaling. 6: rs3. PMID 23322906 DOI: 10.1126/Scisignal.2003305  0.556
2011 Kim YG, Shaw MH, Warner N, Park JH, Chen F, Ogura Y, Núñez G. Cutting edge: Crohn's disease-associated Nod2 mutation limits production of proinflammatory cytokines to protect the host from Enterococcus faecalis-induced lethality. Journal of Immunology (Baltimore, Md. : 1950). 187: 2849-52. PMID 21849681 DOI: 10.4049/jimmunol.1001854  0.31
2011 Kim YG, Kamada N, Shaw MH, Warner N, Chen GY, Franchi L, Núñez G. The Nod2 sensor promotes intestinal pathogen eradication via the chemokine CCL2-dependent recruitment of inflammatory monocytes. Immunity. 34: 769-80. PMID 21565531 DOI: 10.1016/j.immuni.2011.04.013  0.357
2009 Franchi L, Warner N, Viani K, Nuñez G. Function of Nod-like receptors in microbial recognition and host defense. Immunological Reviews. 227: 106-28. PMID 19120480 DOI: 10.1111/J.1600-065X.2008.00734.X  0.311
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