Timothy Hughes - Publications

University of Oslo, Oslo, Oslo, Norway 

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Year Citation  Score
2015 Hughes T, Hansson L, Sønderby IE, Athanasiu L, Zuber V, Tesli M, Song J, Hultman CM, Bergen SE, Landén M, Melle I, Andreassen OA, Djurovic S. A Loss-of-Function Variant in a Minor Isoform of ANK3 Protects Against Bipolar Disorder and Schizophrenia. Biological Psychiatry. PMID 26682468 DOI: 10.1016/j.biopsych.2015.09.021  0.92
2015 Pelossof R, Singh I, Yang JL, Weirauch MT, Hughes TR, Leslie CS. Affinity regression predicts the recognition code of nucleic acid-binding proteins. Nature Biotechnology. PMID 26571099 DOI: 10.1038/nbt.3343  0.92
2015 Loedige I, Jakob L, Treiber T, Ray D, Stotz M, Treiber N, Hennig J, Cook KB, Morris Q, Hughes TR, Engelmann JC, Krahn MP, Meister G. The Crystal Structure of the NHL Domain in Complex with RNA Reveals the Molecular Basis of Drosophila Brain-Tumor-Mediated Gene Regulation. Cell Reports. PMID 26527002 DOI: 10.1016/j.celrep.2015.09.068  0.92
2015 Garton M, Najafabadi HS, Schmitges FW, Radovani E, Hughes TR, Kim PM. A structural approach reveals how neighbouring C2H2 zinc fingers influence DNA binding specificity. Nucleic Acids Research. 43: 9147-57. PMID 26384429 DOI: 10.1093/nar/gkv919  0.92
2015 Ding P, McFarland KA, Jin S, Tong G, Duan B, Yang A, Hughes TR, Liu J, Dove SL, Navarre WW, Xia B. A Novel AT-Rich DNA Recognition Mechanism for Bacterial Xenogeneic Silencer MvaT. Plos Pathogens. 11: e1004967. PMID 26068099 DOI: 10.1371/journal.ppat.1004967  0.92
2015 Laver JD, Li X, Ray D, Cook KB, Hahn NA, Nabeel-Shah S, Kekis M, Luo H, Marsolais AJ, Fung KY, Hughes TR, Westwood JT, Sidhu SS, Morris Q, Lipshitz HD, et al. Brain tumor is a sequence-specific RNA-binding protein that directs maternal mRNA clearance during the Drosophila maternal-to-zygotic transition. Genome Biology. 16: 94. PMID 25962635 DOI: 10.1186/s13059-015-0659-4  0.92
2015 Najafabadi HS, Albu M, Hughes TR. Identification of C2H2-ZF binding preferences from ChIP-seq data using RCADE. Bioinformatics (Oxford, England). 31: 2879-81. PMID 25953800 DOI: 10.1093/bioinformatics/btv284  0.92
2015 Narasimhan K, Lambert SA, Yang AW, Riddell J, Mnaimneh S, Zheng H, Albu M, Najafabadi HS, Reece-Hoyes JS, Fuxman Bass JI, Walhout AJ, Weirauch MT, Hughes TR. Mapping and analysis of Caenorhabditis elegans transcription factor sequence specificities. Elife. 4. PMID 25905672 DOI: 10.7554/eLife.06967  0.92
2015 Najafabadi HS, Mnaimneh S, Schmitges FW, Garton M, Lam KN, Yang A, Albu M, Weirauch MT, Radovani E, Kim PM, Greenblatt J, Frey BJ, Hughes TR. C2H2 zinc finger proteins greatly expand the human regulatory lexicon. Nature Biotechnology. 33: 555-62. PMID 25690854 DOI: 10.1038/nbt.3128  0.92
2015 Ramaglia V, Jackson SJ, Hughes TR, Neal JW, Baker D, Morgan BP. Complement activation and expression during chronic relapsing experimental autoimmune encephalomyelitis in the Biozzi ABH mouse. Clinical and Experimental Immunology. 180: 432-41. PMID 25619542 DOI: 10.1111/cei.12595  0.92
2015 Xiong HY, Alipanahi B, Lee LJ, Bretschneider H, Merico D, Yuen RK, Hua Y, Gueroussov S, Najafabadi HS, Hughes TR, Morris Q, Barash Y, Krainer AR, Jojic N, Scherer SW, et al. RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease. Science (New York, N.Y.). 347: 1254806. PMID 25525159 DOI: 10.1126/science.1254806  0.92
2015 Cook KB, Hughes TR, Morris QD. High-throughput characterization of protein-RNA interactions. Briefings in Functional Genomics. 14: 74-89. PMID 25504152 DOI: 10.1093/bfgp/elu047  0.92
2014 de Boer CG, Hughes TR. Poly-dA:dT tracts form an in vivo nucleosomal turnstile. Plos One. 9: e110479. PMID 25353956 DOI: 10.1371/journal.pone.0110479  0.92
2014 Sullivan AM, Arsovski AA, Lempe J, Bubb KL, Weirauch MT, Sabo PJ, Sandstrom R, Thurman RE, Neph S, Reynolds AP, Stergachis AB, Vernot B, Johnson AK, Haugen E, Sullivan ST, ... ... Hughes TR, et al. Mapping and dynamics of regulatory DNA and transcription factor networks in A. thaliana. Cell Reports. 8: 2015-30. PMID 25220462 DOI: 10.1016/j.celrep.2014.08.019  0.92
2014 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, ... ... Hughes TR, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 158: 1431-43. PMID 25215497 DOI: 10.1016/j.cell.2014.08.009  0.92
2014 Norris AD, Gao S, Norris ML, Ray D, Ramani AK, Fraser AG, Morris Q, Hughes TR, Zhen M, Calarco JA. A pair of RNA-binding proteins controls networks of splicing events contributing to specialization of neural cell types. Molecular Cell. 54: 946-59. PMID 24910101 DOI: 10.1016/j.molcel.2014.05.004  0.92
2014 Schoberle TJ, Nguyen-Coleman CK, Herold J, Yang A, Weirauch M, Hughes TR, McMurray JS, May GS. A Novel C2H2 Transcription Factor that Regulates gliA Expression Interdependently with GliZ in Aspergillus fumigatus Plos Genetics. 10. PMID 24784729 DOI: 10.1371/journal.pgen.1004336  0.92
2014 Steiner T, Francescut L, Byrne S, Hughes T, Jayanthi A, Guschina I, Harwood J, Cianflone K, Stover C, Francis S. Protective role for properdin in progression of experimental murine atherosclerosis. Plos One. 9: e92404. PMID 24667818 DOI: 10.1371/journal.pone.0092404  0.92
2014 Li J, Kim T, Nutiu R, Ray D, Hughes TR, Zhang Z. Identifying mRNA sequence elements for target recognition by human Argonaute proteins. Genome Research. 24: 775-85. PMID 24663241 DOI: 10.1101/gr.162230.113  0.92
2014 de Boer CG, van Bakel H, Tsui K, Li J, Morris QD, Nislow C, Greenblatt JF, Hughes TR. A unified model for yeast transcript definition. Genome Research. 24: 154-66. PMID 24170600 DOI: 10.1101/gr.164327.113  0.92
2013 Smith SA, Ray D, Cook KB, Mallory MJ, Hughes TR, Lynch KW. Paralogs hnRNP L and hnRNP LL exhibit overlapping but distinct RNA binding constraints. Plos One. 8: e80701. PMID 24244709 DOI: 10.1371/journal.pone.0080701  0.92
2013 Sivasankar B, Hughes TR, Morgan BP, Gray LC, Van Den Berg CW. Retraction: Modulation of CD59 expression by restrictive silencer factor-derived peptides in cancer immunotherapy for neuroblastoma (Cancer Research (2008) 68, (5979-5987)) Cancer Research. 73: 6839. PMID 24204029 DOI: 10.1158/0008-5472.CAN-13-2936  0.92
2013 Cole DS, Sivasankar B, Hughes TR, Morgan BP. Retraction: P53 regulates cellular resistance to complement lysis through enhanced expression of CD59 (Cancer Research (2006) 66, (2451-2458)) Cancer Research. 73: 6838. PMID 24204028 DOI: 10.1158/0008-5472.CAN-13-2935  0.92
2013 Sebé-Pedrós A, Ariza-Cosano A, Weirauch MT, Leininger S, Yang A, Torruella G, Adamski M, Adamska M, Hughes TR, Gómez-Skarmeta JL, Ruiz-Trillo I. Early evolution of the T-box transcription factor family. Proceedings of the National Academy of Sciences of the United States of America. 110: 16050-5. PMID 24043797 DOI: 10.1073/pnas.1309748110  0.92
2013 Hughes TR, de Boer CG. Mapping yeast transcriptional networks. Genetics. 195: 9-36. PMID 24018767 DOI: 10.1534/genetics.113.153262  0.92
2013 Ray D, Kazan H, Cook KB, Weirauch MT, Najafabadi HS, Li X, Gueroussov S, Albu M, Zheng H, Yang A, Na H, Irimia M, Matzat LH, Dale RK, Smith SA, ... ... Hughes TR, et al. A compendium of RNA-binding motifs for decoding gene regulation. Nature. 499: 172-7. PMID 23846655 DOI: 10.1038/nature12311  0.92
2013 Laudisi F, Spreafico R, Evrard M, Hughes TR, Mandriani B, Kandasamy M, Morgan BP, Sivasankar B, Mortellaro A. Cutting edge: the NLRP3 inflammasome links complement-mediated inflammation and IL-1β release. Journal of Immunology (Baltimore, Md. : 1950). 191: 1006-10. PMID 23817414 DOI: 10.4049/jimmunol.1300489  0.92
2013 Chang KN, Zhong S, Weirauch MT, Hon G, Pelizzola M, Li H, Huang SS, Schmitz RJ, Urich MA, Kuo D, Nery JR, Qiao H, Yang A, Jamali A, Chen H, ... ... Hughes TR, et al. Temporal transcriptional response to ethylene gas drives growth hormone cross-regulation in Arabidopsis. Elife. 2: e00675. PMID 23795294 DOI: 10.7554/eLife.00675  0.92
2013 Reece-Hoyes JS, Pons C, Diallo A, Mori A, Shrestha S, Kadreppa S, Nelson J, Diprima S, Dricot A, Lajoie BR, Ribeiro PS, Weirauch MT, Hill DE, Hughes TR, Myers CL, et al. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Molecular Cell. 51: 116-27. PMID 23791784 DOI: 10.1016/j.molcel.2013.05.018  0.92
2013 van Bakel H, Tsui K, Gebbia M, Mnaimneh S, Hughes TR, Nislow C. A compendium of nucleosome and transcript profiles reveals determinants of chromatin architecture and transcription. Plos Genetics. 9: e1003479. PMID 23658529 DOI: 10.1371/journal.pgen.1003479  0.92
2013 Triantafilou K, Hughes TR, Triantafilou M, Morgan BP. The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation. Journal of Cell Science. 126: 2903-13. PMID 23613465 DOI: 10.1242/jcs.124388  0.92
2013 Mann IK, Chatterjee R, Zhao J, He X, Weirauch MT, Hughes TR, Vinson C. CG methylated microarrays identify a novel methylated sequence bound by the CEBPB|ATF4 heterodimer that is active in vivo. Genome Research. 23: 988-97. PMID 23590861 DOI: 10.1101/gr.146654.112  0.92
2013 Sofat R, Mangione PP, Gallimore JR, Hakobyan S, Hughes TR, Shah T, Goodship T, D'Aiuto F, Langenberg C, Wareham N, Morgan BP, Pepys MB, Hingorani AD. Distribution and determinants of circulating complement factor H concentration determined by a high-throughput immunonephelometric assay. Journal of Immunological Methods. 390: 63-73. PMID 23376722 DOI: 10.1016/j.jim.2013.01.009  0.92
2013 Weirauch MT, Cote A, Norel R, Annala M, Zhao Y, Riley TR, Saez-Rodriguez J, Cokelaer T, Vedenko A, Talukder S, Bussemaker HJ, Morris QD, Bulyk ML, Stolovitzky G, ... Hughes TR, et al. Evaluation of methods for modeling transcription factor sequence specificity. Nature Biotechnology. 31: 126-34. PMID 23354101 DOI: 10.1038/nbt.2486  0.92
2013 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, et al. DNA-binding specificities of human transcription factors. Cell. 152: 327-39. PMID 23332764 DOI: 10.1016/j.cell.2012.12.009  0.92
2013 Kandasamy M, Ying PC, Ho AW, Sumatoh HR, Schlitzer A, Hughes TR, Kemeny DM, Morgan BP, Ginhoux F, Sivasankar B. Complement mediated signaling on pulmonary CD103(+) dendritic cells is critical for their migratory function in response to influenza infection. Plos Pathogens. 9: e1003115. PMID 23326231 DOI: 10.1371/journal.ppat.1003115  0.92
2013 Killick R, Hughes TR, Morgan BP, Lovestone S. Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH. Neuroscience Letters. 533: 96-9. PMID 23153828 DOI: 10.1016/j.neulet.2012.11.008  0.92
2013 Killick R, Hughes TR, Morgan BP, Lovestone S. Corrigendum to Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH [Neurosci. Lett. 533 (2013) 96-99] Neuroscience Letters. 545: 144. DOI: 10.1016/j.neulet.2013.05.004  0.92
2012 Gilfillan GD, Hughes T, Sheng Y, Hjorthaug HS, Straub T, Gervin K, Harris JR, Undlien DE, Lyle R. Limitations and possibilities of low cell number ChIP-seq. Bmc Genomics. 13: 645. PMID 23171294 DOI: 10.1186/1471-2164-13-645  0.92
2012 Xu M, Soloveychik M, Ranger M, Schertzberg M, Shah Z, Raisner R, Venkatasubrahmanyan S, Tsui K, Gebbia M, Hughes T, van Bakel H, Nislow C, Madhani HD, Meneghini MD. Timing of transcriptional quiescence during gametogenesis is controlled by global histone H3K4 demethylation. Developmental Cell. 23: 1059-71. PMID 23123093 DOI: 10.1016/j.devcel.2012.10.005  0.92
2012 Hamfjord J, Stangeland AM, Hughes T, Skrede ML, Tveit KM, Ikdahl T, Kure EH. Differential expression of miRNAs in colorectal cancer: Comparison of paired tumor tissue and adjacent normal mucosa using high-throughput sequencing Plos One. 7. PMID 22529906 DOI: 10.1371/journal.pone.0034150  0.92
2012 Ramaglia V, Hughes TR, Donev RM, Ruseva MM, Wu X, Huitinga I, Baas F, Neal JW, Morgan BP. C3-dependent mechanism of microglial priming relevant to multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 109: 965-70. PMID 22219359 DOI: 10.1073/pnas.1111924109  0.92
2012 De Boer CG, Hughes TR. YeTFaSCo: A database of evaluated yeast transcription factor sequence specificities Nucleic Acids Research. 40: D169-D179. PMID 22102575 DOI: 10.1093/nar/gkr993  0.92
2012 Selmer KK, Gilfillan GD, Strømme P, Lyle R, Hughes T, Hjorthaug HS, Brandal K, Nakken S, Misceo D, Egeland T, Munthe LA, Braekken SK, Undlien DE. A mild form of Mucopolysaccharidosis IIIB diagnosed with targeted next-generation sequencing of linked genomic regions European Journal of Human Genetics. 20: 58-63. PMID 21712855 DOI: 10.1038/ejhg.2011.126  0.92
2011 van Bakel H, Stout JM, Cote AG, Tallon CM, Sharpe AG, Hughes TR, Page JE. The draft genome and transcriptome of Cannabis sativa. Genome Biology. 12: R102. PMID 22014239 DOI: 10.1186/gb-2011-12-10-r102  0.92
2011 Gabut M, Samavarchi-Tehrani P, Wang X, Slobodeniuc V, O'Hanlon D, Sung HK, Alvarez M, Talukder S, Pan Q, Mazzoni EO, Nedelec S, Wichterle H, Woltjen K, Hughes TR, Zandstra PW, et al. An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming. Cell. 147: 132-46. PMID 21924763 DOI: 10.1016/j.cell.2011.08.023  0.92
2011 Lewis RD, Perry MJ, Guschina IA, Jackson CL, Morgan BP, Hughes TR. CD55 deficiency protects against atherosclerosis in ApoE-deficient mice via C3a modulation of lipid metabolism. The American Journal of Pathology. 179: 1601-7. PMID 21816131 DOI: 10.1016/j.ajpath.2011.06.015  0.92
2011 Huang E, Talukder S, Hughes TR, Curk T, Zupan B, Shaulsky G, Katoh-Kurasawa M. BzpF is a CREB-like transcription factor that regulates spore maturation and stability in Dictyostelium. Developmental Biology. 358: 137-46. PMID 21810415 DOI: 10.1016/j.ydbio.2011.07.017  0.92
2011 Gordon BR, Li Y, Cote A, Weirauch MT, Ding P, Hughes TR, Navarre WW, Xia B, Liu J. Structural basis for recognition of AT-rich DNA by unrelated xenogeneic silencing proteins. Proceedings of the National Academy of Sciences of the United States of America. 108: 10690-5. PMID 21673140 DOI: 10.1073/pnas.1102544108  0.92
2011 Morris Q, Bulyk ML, Hughes TR. Jury remains out on simple models of transcription factor specificity. Nature Biotechnology. 29: 483-4. PMID 21654663 DOI: 10.1038/nbt.1892  0.92
2011 Lueck K, Wasmuth S, Williams J, Hughes TR, Morgan BP, Lommatzsch A, Greenwood J, Moss SE, Pauleikhoff D. Sub-lytic C5b-9 induces functional changes in retinal pigment epithelial cells consistent with age-related macular degeneration. Eye (London, England). 25: 1074-82. PMID 21597483 DOI: 10.1038/eye.2011.109  0.92
2011 Weirauch MT, Hughes TR. A catalogue of eukaryotic transcription factor types, their evolutionary origin, and species distribution. Sub-Cellular Biochemistry. 52: 25-73. PMID 21557078 DOI: 10.1007/978-90-481-9069-0_3  0.92
2011 Lam KN, van Bakel H, Cote AG, van der Ven A, Hughes TR. Sequence specificity is obtained from the majority of modular C2H2 zinc-finger arrays. Nucleic Acids Research. 39: 4680-90. PMID 21321018 DOI: 10.1093/nar/gkq1303  0.92
2011 Stead MB, Marshburn S, Mohanty BK, Mitra J, Pena Castillo L, Ray D, van Bakel H, Hughes TR, Kushner SR. Analysis of Escherichia coli RNase E and RNase III activity in vivo using tiling microarrays. Nucleic Acids Research. 39: 3188-203. PMID 21149258 DOI: 10.1093/nar/gkq1242  0.92
2011 Cook KB, Kazan H, Zuberi K, Morris Q, Hughes TR. RBPDB: a database of RNA-binding specificities. Nucleic Acids Research. 39: D301-8. PMID 21036867 DOI: 10.1093/nar/gkq1069  0.92
2011 van Bakel H, Nislow C, Blencowe BJ, Hughes TR. Response to "The reality of pervasive transcription" Plos Biology. 9. DOI: 10.1371/journal.pbio.1001102  0.92
2011 Hughes TR. Introduction to “a handbook of transcription factors” Sub-Cellular Biochemistry. 52. DOI: 10.1007/978-90-481-9069-0_1  0.92
2010 Kaplan N, Hughes TR, Lieb JD, Widom J, Segal E. Contribution of histone sequence preferences to nucleosome organization: proposed definitions and methodology. Genome Biology. 11: 140. PMID 21118582 DOI: 10.1186/gb-2010-11-11-140  0.92
2010 Chowdhury S, Lloyd-Price J, Smolander OP, Baici WCV, Hughes TR, Yli-Harja O, Chua G, Ribeiro AS. Information propagation within the Genetic Network of Saccharomyces cerevisiae Bmc Systems Biology. 4. PMID 20977725 DOI: 10.1186/1752-0509-4-143  0.92
2010 Santos MA, Turinsky AL, Ong S, Tsai J, Berger MF, Badis G, Talukder S, Gehrke AR, Bulyk ML, Hughes TR, Wodak SJ. Objective sequence-based subfamily classifications of mouse homeodomains reflect their in vitro DNA-binding preferences. Nucleic Acids Research. 38: 7927-42. PMID 20705649 DOI: 10.1093/nar/gkq714  0.92
2010 Gray LC, Hughes TR, Van den Berg CW. Binding of human antigen R (HuR) to an AU-rich element (ARE) in the 3′untranslated region (3′UTR) reduces the expression of decay accelerating factor (DAF) Molecular Immunology. 47: 2545-2551. PMID 20692039 DOI: 10.1016/j.molimm.2010.07.002  0.92
2010 Kaplan N, Moore I, Fondufe-Mittendorf Y, Gossett AJ, Tillo D, Field Y, Hughes TR, Lieb JD, Widom J, Segal E. Nucleosome sequence preferences influence in vivo nucleosome organization. Nature Structural & Molecular Biology. 17: 918-20; author reply. PMID 20683473 DOI: 10.1038/nsmb0810-918  0.92
2010 Kazan H, Ray D, Chan ET, Hughes TR, Morris Q. RNAcontext: a new method for learning the sequence and structure binding preferences of RNA-binding proteins. Plos Computational Biology. 6: e1000832. PMID 20617199 DOI: 10.1371/journal.pcbi.1000832  0.92
2010 Weirauch MT, Hughes TR. Dramatic changes in transcription factor binding over evolutionary time. Genome Biology. 11: 122. PMID 20519030 DOI: 10.1186/gb-2010-11-6-122  0.92
2010 Wei GH, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, ... ... Hughes TR, et al. Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo. The Embo Journal. 29: 2147-60. PMID 20517297 DOI: 10.1038/emboj.2010.106  0.92
2010 van Bakel H, Nislow C, Blencowe BJ, Hughes TR. Most "dark matter" transcripts are associated with known genes. Plos Biology. 8: e1000371. PMID 20502517 DOI: 10.1371/journal.pbio.1000371  0.92
2010 Beaver JE, Tasan M, Gibbons FD, Tian W, Hughes TR, Roth FP. FuncBase: a resource for quantitative gene function annotation. Bioinformatics (Oxford, England). 26: 1806-7. PMID 20495000 DOI: 10.1093/bioinformatics/btq265  0.92
2010 Jolma A, Kivioja T, Toivonen J, Cheng L, Wei G, Enge M, Taipale M, Vaquerizas JM, Yan J, Sillanpää MJ, Bonke M, Palin K, Talukder S, Hughes TR, Luscombe NM, et al. Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities. Genome Research. 20: 861-73. PMID 20378718 DOI: 10.1101/gr.100552.109  0.92
2010 Tillo D, Kaplan N, Moore IK, Fondufe-Mittendorf Y, Gossett AJ, Field Y, Lieb JD, Widom J, Segal E, Hughes TR. High nucleosome occupancy is encoded at human regulatory sequences. Plos One. 5: e9129. PMID 20161746 DOI: 10.1371/journal.pone.0009129  0.92
2010 Weirauch MT, Hughes TR. Conserved expression without conserved regulatory sequence: the more things change, the more they stay the same. Trends in Genetics : Tig. 26: 66-74. PMID 20083321 DOI: 10.1016/j.tig.2009.12.002  0.92
2010 Jaeger SA, Chan ET, Berger MF, Stottmann R, Hughes TR, Bulyk ML. Conservation and regulatory associations of a wide affinity range of mouse transcription factor binding sites. Genomics. 95: 185-95. PMID 20079828 DOI: 10.1016/j.ygeno.2010.01.002  0.92
2010 Copland DA, Hussain K, Baalasubramanian S, Hughes TR, Morgan BP, Xu H, Dick AD, Nicholson LB. Systemic and local anti-C5 therapy reduces the disease severity in experimental autoimmune uveoretinitis. Clinical and Experimental Immunology. 159: 303-14. PMID 20002447 DOI: 10.1111/j.1365-2249.2009.04070.x  0.92
2010 Lewis RD, Jackson CL, Morgan BP, Hughes TR. The membrane attack complex of complement drives the progression of atherosclerosis in apolipoprotein E knockout mice. Molecular Immunology. 47: 1098-105. PMID 19959238 DOI: 10.1016/j.molimm.2009.10.035  0.92
2010 Gould CM, Diella F, Via A, Puntervoll P, Gemünd C, Chabanis-Davidson S, Michael S, Sayadi A, Bryne JC, Chica C, Seiler M, Davey NE, Haslam N, Weatheritt RJ, Budd A, ... Hughes T, et al. ELM: the status of the 2010 eukaryotic linear motif resource. Nucleic Acids Research. 38: D167-80. PMID 19920119 DOI: 10.1093/nar/gkp1016  0.92
2009 Tillo D, Hughes TR. G+C content dominates intrinsic nucleosome occupancy Bmc Bioinformatics. 10. PMID 20028554 DOI: 10.1186/1471-2105-10-442  0.92
2009 van Bakel H, Hughes TR. Establishing legitimacy and function in the new transcriptome Briefings in Functional Genomics and Proteomics. 8: 424-436. PMID 19833698 DOI: 10.1093/bfgp/elp037  0.92
2009 Khanna M, Van Bakel H, Tang X, Calarco JA, Babak T, Guo G, Emili A, Greenblatt JF, Hughes TR, Krogan NJ, Blencowe BJ. A systematic characterization of Cwc21, the yeast ortholog of the human spliceosomal protein SRm300. Rna (New York, N.Y.). 15: 2174-85. PMID 19789211 DOI: 10.1261/rna.1790509  0.92
2009 Fillingham J, Kainth P, Lambert JP, van Bakel H, Tsui K, Peña-Castillo L, Nislow C, Figeys D, Hughes TR, Greenblatt J, Andrews BJ. Two-color cell array screen reveals interdependent roles for histone chaperones and a chromatin boundary regulator in histone gene repression. Molecular Cell. 35: 340-51. PMID 19683497 DOI: 10.1016/j.molcel.2009.06.023  0.92
2009 Ray D, Kazan H, Chan ET, Peña Castillo L, Chaudhry S, Talukder S, Blencowe BJ, Morris Q, Hughes TR. Rapid and systematic analysis of the RNA recognition specificities of RNA-binding proteins. Nature Biotechnology. 27: 667-70. PMID 19561594 DOI: 10.1038/nbt.1550  0.92
2009 Badis G, Berger MF, Philippakis AA, Talukder S, Gehrke AR, Jaeger SA, Chan ET, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang CF, Coburn D, Newburger DE, Morris Q, ... Hughes TR, et al. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.). 324: 1720-3. PMID 19443739 DOI: 10.1126/science.1162327  0.92
2009 Chan ET, Quon GT, Chua G, Babak T, Trochesset M, Zirngibl RA, Aubin J, Ratcliffe MJ, Wilde A, Brudno M, Morris QD, Hughes TR. Conservation of core gene expression in vertebrate tissues. Journal of Biology. 8: 33. PMID 19371447 DOI: 10.1186/jbiol130  0.92
2009 Fulton DL, Sundararajan S, Badis G, Hughes TR, Wasserman WW, Roach JC, Sladek R. TFCat: the curated catalog of mouse and human transcription factors. Genome Biology. 10: R29. PMID 19284633 DOI: 10.1186/gb-2009-10-3-r29  0.92
2009 Kainth P, Sassi HE, Peña-Castillo L, Chua G, Hughes TR, Andrews B. Comprehensive genetic analysis of transcription factor pathways using a dual reporter gene system in budding yeast. Methods (San Diego, Calif.). 48: 258-64. PMID 19269327 DOI: 10.1016/j.ymeth.2009.02.015  0.92
2009 Coughlin DJ, Babak T, Nihranz C, Hughes TR, Engelke DR. Prediction and verification of mouse tRNA gene families Rna Biology. 6. PMID 19246989  0.92
2009 Hughes TR. 'Validation' in genome-scale research Journal of Biology. 8. PMID 19222867 DOI: 10.1186/jbiol104  0.92
2009 Blencowe B, Brenner S, Hughes T, Morris Q. Post-transcriptional gene regulation: RNA-protein interactions, RNA processing, mRNA stability and localization. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 545-8. PMID 19209730  0.92
2009 Hughes TR, Ross KS, Cowan GJ, Sivasankar B, Harris CL, Mitchell TJ, Morgan BP. Identification of the high affinity binding site in the Streptococcus intermedius toxin intermedilysin for its membrane receptor, the human complement regulator CD59. Molecular Immunology. 46: 1561-7. PMID 19200600 DOI: 10.1016/j.molimm.2009.01.003  0.92
2009 Kaplan N, Moore IK, Fondufe-Mittendorf Y, Gossett AJ, Tillo D, Field Y, LeProust EM, Hughes TR, Lieb JD, Widom J, Segal E. The DNA-encoded nucleosome organization of a eukaryotic genome. Nature. 458: 362-6. PMID 19092803 DOI: 10.1038/nature07667  0.92
2009 Alleyne TM, Peña-Castillo L, Badis G, Talukder S, Berger MF, Gehrke AR, Philippakis AA, Bulyk ML, Morris QD, Hughes TR. Predicting the binding preference of transcription factors to individual DNA k-mers. Bioinformatics (Oxford, England). 25: 1012-8. PMID 19088121 DOI: 10.1093/bioinformatics/btn645  0.92
2009 Ruseva MM, Hughes TR, Donev RM, Sivasankar B, Pickering MC, Wu X, Harris CL, Morgan BP. Crry deficiency in complement sufficient mice: C3 consumption occurs without associated renal injury. Molecular Immunology. 46: 803-11. PMID 18947875 DOI: 10.1016/j.molimm.2008.09.003  0.92
2009 Quon G, Teh YW, Chan E, Hughes T, Brudno M, Morris Q. A mixture model for the evolution of gene expression in non-homogeneous datasets Advances in Neural Information Processing Systems 21 - Proceedings of the 2008 Conference. 1297-1304.  0.92
2008 Badis G, Chan ET, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson CD, Gossett AJ, Hasinoff MJ, Warren CL, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, ... ... Hughes TR, et al. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular Cell. 32: 878-87. PMID 19111667 DOI: 10.1016/j.molcel.2008.11.020  0.92
2008 Cheung V, Chua G, Batada NN, Landry CR, Michnick SW, Hughes TR, Winston F. Chromatin- and transcription-related factors repress transcription from within coding regions throughout the Saccharomyces cerevisiae genome. Plos Biology. 6: e277. PMID 18998772 DOI: 10.1371/journal.pbio.0060277  0.92
2008 Hughes T, Liberles DA. Whole-genome duplications in the ancestral vertebrate are detectable in the distribution of gene family sizes of tetrapod species. Journal of Molecular Evolution. 67: 343-57. PMID 18815825 DOI: 10.1007/s00239-008-9145-x  0.92
2008 Harris SM, Harvey EJ, Hughes TR, Ramji DP. The interferon-gamma-mediated inhibition of lipoprotein lipase gene transcription in macrophages involves casein kinase 2- and phosphoinositide-3-kinase-mediated regulation of transcription factors Sp1 and Sp3. Cellular Signalling. 20: 2296-301. PMID 18793716 DOI: 10.1016/j.cellsig.2008.08.016  0.92
2008 Donev RM, Gray LC, Sivasankar B, Hughes TR, van den Berg CW, Morgan BP. Modulation of CD59 expression by restrictive silencer factor-derived peptides in cancer immunotherapy for neuroblastoma. Cancer Research. 68: 5979-87. PMID 18632654 DOI: 10.1158/0008-5472.CAN-07-6828  0.92
2008 Willis IM, Chua G, Tong AH, Brost RL, Hughes TR, Boone C, Moir RD. Genetic interactions of MAF1 identify a role for Med20 in transcriptional repression of ribosomal protein genes. Plos Genetics. 4: e1000112. PMID 18604275 DOI: 10.1371/journal.pgen.1000112  0.92
2008 Lovegrove FE, Peña-Castillo L, Liles WC, Hughes TR, Kain KC. Plasmodium falciparum shows transcriptional versatility within the human host. Trends in Parasitology. 24: 288-91. PMID 18538633 DOI: 10.1016/j.pt.2008.04.004  0.92
2008 Rutherford JC, Chua G, Hughes T, Cardenas ME, Heitman J. A Mep2-dependent transcriptional profile links permease function to gene expression during pseudohyphal growth in Saccharomyces cerevisiae. Molecular Biology of the Cell. 19: 3028-39. PMID 18434596 DOI: 10.1091/mbc.E08-01-0033  0.92
2008 Hughes T, Liberles DA. The power-law distribution of gene family size is driven by the pseudogenisation rate's heterogeneity between gene families. Gene. 414: 85-94. PMID 18378100 DOI: 10.1016/j.gene.2008.02.014  0.92
2007 Hughes T, Liberles DA. The pattern of evolution of smaller-scale gene duplicates in mammalian genomes is more consistent with neo- than subfunctionalisation. Journal of Molecular Evolution. 65: 574-88. PMID 17957399 DOI: 10.1007/s00239-007-9041-9  0.92
2007 Hughes T, Ekman D, Ardawatia H, Elofsson A, Liberles DA. Evaluating dosage compensation as a cause of duplicate gene retention in Paramecium tetraurelia. Genome Biology. 8: 213. PMID 17521457 DOI: 10.1186/gb-2007-8-5-213  0.92
2004 Hughes T, Hyun Y, Liberles DA. Visualising very large phylogenetic trees in three dimensional hyperbolic space. Bmc Bioinformatics. 5: 48. PMID 15117420 DOI: 10.1186/1471-2105-5-48  0.92
Low-probability matches
2020 Zlokovic BV, Gottesman RF, Bernstein KE, Seshadri S, McKee A, Snyder H, Greenberg SM, Yaffe K, Schaffer CB, Yuan C, Hughes TM, Daemen MJ, Williamson JD, González HM, Schneider J, et al. Vascular contributions to cognitive impairment and dementia (VCID): A report from the 2018 National Heart, Lung, and Blood Institute and National Institute of Neurological Disorders and Stroke Workshop. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33030307 DOI: 10.1002/alz.12157  0.04
2020 Jolma A, Zhang J, Mondragón E, Morgunova E, Kivioja T, Laverty KU, Yin Y, Zhu F, Bourenkov G, Morris Q, Hughes TR, Maher LJ, Taipale J. Binding specificities of human RNA-binding proteins toward structured and linear RNA sequences. Genome Research. PMID 32703884 DOI: 10.1101/gr.258848.119  0.04
2017 Collins KM, Kainov YA, Christodolou E, Ray D, Morris Q, Hughes T, Taylor IA, Makeyev EV, Ramos A. An RRM-ZnF RNA recognition module targets RBM10 to exonic sequences to promote exon exclusion. Nucleic Acids Research. PMID 28379442 DOI: 10.1093/nar/gkx225  0.04
2016 Solana J, Irimia M, Ayoub S, Orejuela MR, Zywitza V, Jens M, Tapial J, Ray D, Morris Q, Hughes TR, Blencowe BJ, Rajewsky N. Conserved functional antagonism of CELF and MBNL proteins controls stem cell-specific alternative splicing in planarians. Elife. 5. PMID 27502555 DOI: 10.7554/eLife.16797  0.04
2021 Mullish BH, Marchesi JR, McDonald JAK, Pass DA, Masetti G, Michael DR, Plummer S, Jack AA, Davies TS, Hughes TR, Wang D. Probiotics reduce self-reported symptoms of upper respiratory tract infection in overweight and obese adults: should we be considering probiotics during viral pandemics? Gut Microbes. 13: 1-9. PMID 33764850 DOI: 10.1080/19490976.2021.1900997  0.01
2021 Friščić J, Böttcher M, Reinwald C, Bruns H, Wirth B, Popp SJ, Walker KI, Ackermann JA, Chen X, Turner J, Zhu H, Seyler L, Euler M, Kirchner P, Krüger R, ... ... Hughes TR, et al. The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts. Immunity. PMID 33761330 DOI: 10.1016/j.immuni.2021.03.003  0.01
2021 Bailey MJ, Soliman EZ, McClure LA, Howard G, Howard VJ, Judd SE, Unverzagt F, Wadley V, Sachs BC, Hughes T. Relation of Atrial Fibrillation to Cognitive Decline (from the REasons for Geographic and Racial Differences in Stroke [REGARDS] Study). The American Journal of Cardiology. PMID 33684372 DOI: 10.1016/j.amjcard.2021.02.036  0.01
2021 O'Connell KS, Sønderby IE, Frei O, van der Meer D, Athanasiu L, Smeland OB, Alnæs D, Kaufmann T, Westlye LT, Steen VM, Andreassen OA, Hughes T, Djurovic S. Association between complement component 4A expression, cognitive performance and brain imaging measures in UK Biobank. Psychological Medicine. 1-11. PMID 33653435 DOI: 10.1017/S0033291721000179  0.01
2021 Akkouh IA, Hughes T, Steen VM, Glover JC, Andreassen OA, Djurovic S, Szabo A. Transcriptome analysis reveals disparate expression of inflammation-related miRNAs and their gene targets in iPSC-astrocytes from people with schizophrenia. Brain, Behavior, and Immunity. PMID 33571628 DOI: 10.1016/j.bbi.2021.01.037  0.01
2021 Yellan I, Yang AWH, Hughes TR. Diverse Eukaryotic CGG Binding Proteins Produced by Independent Domestications of hAT Transposons. Molecular Biology and Evolution. PMID 33561217 DOI: 10.1093/molbev/msab007  0.01
2021 Stone K, Fryer S, Meyer ML, Kucharska-Newton A, Faulkner J, Zieff G, Paterson C, Credeur D, Matsushita K, Hughes TM, Tanaka H, Stoner L. The aortic-femoral arterial stiffness gradient: an atherosclerosis risk in communities (ARIC) study. Journal of Hypertension. PMID 33560059 DOI: 10.1097/HJH.0000000000002808  0.01
2021 Zhang M, Lei M, Qin S, Dong A, Yang A, Li Y, Loppnau P, Hughes TR, Min J, Liu Y. Crystal structure of the BRPF2 PWWP domain in complex with DNA reveals a different binding mode than the HDGF family of PWWP domains. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms. 194688. PMID 33556623 DOI: 10.1016/j.bbagrm.2021.194688  0.01
2021 Reis de Assis D, Szabo A, Requena Osete J, Puppo F, O'Connell KS, A Akkouh I, Hughes T, Frei E, A Andreassen O, Djurovic S. Using iPSC Models to Understand the Role of Estrogen in Neuron-Glia Interactions in Schizophrenia and Bipolar Disorder. Cells. 10. PMID 33494281 DOI: 10.3390/cells10020209  0.01
2021 Sullivan KJ, Ranadive R, Su D, Neyland BR, Hughes TM, Hugenschmidt CE, Lockhart SN, Wong DF, Jack CR, Gottesman RF, Mosley TH, Griswold ME, Windham BG. Imaging-based indices of Neuropathology and gait speed decline in older adults: the atherosclerosis risk in communities study. Brain Imaging and Behavior. PMID 33439369 DOI: 10.1007/s11682-020-00435-y  0.01
2021 Kantarjian HM, Hughes TP, Larson RA, Kim DW, Issaragrisil S, le Coutre P, Etienne G, Boquimpani C, Pasquini R, Clark RE, Dubruille V, Flinn IW, Kyrcz-Krzemien S, Medras E, Zanichelli M, et al. Long-term outcomes with frontline nilotinib versus imatinib in newly diagnosed chronic myeloid leukemia in chronic phase: ENESTnd 10-year analysis. Leukemia. PMID 33414482 DOI: 10.1038/s41375-020-01111-2  0.01
2021 Burke GL, Hughes TM. Arterial Changes Connecting Hypertension to Alzheimer's Disease and Related Dementias. Jacc. Cardiovascular Imaging. 14: 186-188. PMID 33413885 DOI: 10.1016/j.jcmg.2020.10.018  0.01
2021 Heatley SL, Asari K, Schutz CE, Leclercq TM, McClure BJ, Eadie LN, Hughes TP, Yeung DT, White DL. modeling of TKI resistance in the high-risk B-cell acute lymphoblastic leukemia fusion gene - implications for targeted therapy. Leukemia & Lymphoma. 1-13. PMID 33390067 DOI: 10.1080/10428194.2020.1861275  0.01
2020 Schmitz U, Shah JS, Dhungel BP, Monteuuis G, Luu PL, Petrova V, Metierre C, Nair SS, Bailey CG, Saunders VA, Turhan AG, White DL, Branford S, Clark SJ, Hughes TP, et al. Widespread Aberrant Alternative Splicing despite Molecular Remission in Chronic Myeloid Leukaemia Patients. Cancers. 12. PMID 33322625 DOI: 10.3390/cancers12123738  0.01
2020 Dodge HH, Goldstein FC, Wakim NI, Gefen T, Teylan M, Chan KCG, Kukull WA, Barnes LL, Giordani B, Hughes TM, Kramer JH, Loewenstein DA, Marson DC, Mungas DM, Mattek N, et al. Differentiating among stages of cognitive impairment in aging: Version 3 of the Uniform Data Set (UDS) neuropsychological test battery and MoCA index scores. Alzheimer's & Dementia (New York, N. Y.). 6: e12103. PMID 33283037 DOI: 10.1002/trc2.12103  0.01
2020 Ross DM, Hughes TP. There is a best duration of deep molecular response for treatment-free remission, but it is patient-specific, and that is the challenge. British Journal of Haematology. PMID 33169882 DOI: 10.1111/bjh.17111  0.01
2020 Shanmuganathan N, Pagani IS, Ross DM, Park S, Yong AS, Braley JA, Altamura HK, Hiwase DK, Yeung DT, Kim DW, Branford S, Hughes TP. Early BCR-ABL1 kinetics are predictive of subsequent achievement of treatment-free remission in chronic myeloid leukemia. Blood. PMID 32871588 DOI: 10.1182/blood.2020005514  0.01
2020 Kosti A, de Araujo PR, Li WQ, Guardia GDA, Chiou J, Yi C, Ray D, Meliso F, Li YM, Delambre T, Qiao M, Burns SS, Lorbeer FK, Georgi F, Flosbach M, ... ... Hughes TR, et al. The RNA-binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging cancer metabolism and epigenetic regulation. Genome Biology. 21: 195. PMID 32762776 DOI: 10.1186/s13059-020-02115-y  0.01
2020 McClure BJ, Heatley SL, Rehn J, Breen J, Sutton R, Hughes TP, Suppiah R, Revesz T, Osborn M, White D, Yeung DT, White DL. High-risk B-cell acute lymphoblastic leukaemia presenting with hypereosinophilia and acquiring a novel PAX5 fusion on relapse. British Journal of Haematology. PMID 32731299 DOI: 10.1111/bjh.17002  0.01
2020 Pagani IS, Dang P, Saunders VA, Braley J, Thieleke A, Branford S, Hughes TP, Ross DM. Clinical utility of genomic DNA Q-PCR for the monitoring of a patient with atypical e19a2 transcripts in chronic myeloid leukemia. Leukemia & Lymphoma. 1-3. PMID 32508223 DOI: 10.1080/10428194.2020.1772476  0.01
2020 Hughes T, Hansson L, Akkouh I, Hajdarevic R, Bringsli JS, Torsvik A, Inderhaug E, Steen VM, Djurovic S. Runaway multi-allelic copy number variation at the α-defensin locus in African and Asian populations. Scientific Reports. 10: 9101. PMID 32499510 DOI: 10.1038/s41598-020-65675-w  0.01
2020 Sachs BC, Steenland K, Zhao L, Hughes TM, Weintraub S, Dodge HH, Barnes LL, Craft S, Parker ML, Goldstein FC. Expanded Demographic Norms for Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set. Alzheimer Disease and Associated Disorders. PMID 32483017 DOI: 10.1097/WAD.0000000000000388  0.01
2020 Bennett EE, Gianattasio KZ, Hughes TM, Mosley TH, Wong DF, Gottesman RF, Power MC. The association between midlife lipid levels and late-life brain amyloid deposition. Neurobiology of Aging. 92: 73-74. PMID 32402985 DOI: 10.1016/j.neurobiolaging.2020.03.015  0.01
2020 Ross DM, Hughes TP. Treatment-free remission in patients with chronic myeloid leukaemia. Nature Reviews. Clinical Oncology. PMID 32377005 DOI: 10.1038/s41571-020-0367-1  0.01
2020 Stoner L, Meyer ML, Kucharska-Newton A, Stone K, Zieff G, Dave G, Fryer S, Credeur D, Faulkner J, Matsushita K, Hughes TM, Tanaka H. Associations between carotid-femoral and heart-femoral pulse wave velocity in older adults: the Atherosclerosis Risk In Communities study. Journal of Hypertension. PMID 32371771 DOI: 10.1097/HJH.0000000000002449  0.01
2020 Irani YD, Hughes A, Clarson J, Kok CH, Shanmuganathan N, White DL, Yeung DT, Ross DM, Hughes TP, Yong ASM. Successful treatment-free remission in chronic myeloid leukaemia and its association with reduced immune suppressors and increased natural killer cells. British Journal of Haematology. PMID 32352166 DOI: 10.1111/bjh.16718  0.01
2020 Mauro MJ, Hughes TP. Asciminib in Relapsed Chronic Myeloid Leukemia. Reply. The New England Journal of Medicine. 382: 1379. PMID 32242376 DOI: 10.1056/NEJMc2000116#sa2  0.01
2020 Turkina A, Wang J, Mathews V, Saydam G, Jung CW, Al Hashmi HH, Yassin M, Le Clanche S, Miljkovic D, Slader C, Hughes TP. TARGET: a survey of real-world management of chronic myeloid leukaemia across 33 countries. British Journal of Haematology. PMID 32227648 DOI: 10.1111/bjh.16599  0.01
2020 Chakraborti S, Balakrishnan D, Trotter AJ, Gittens WH, Yang AWH, Jolma A, Paterson JR, Świątek S, Plewka J, Curtis FA, Bowers LY, Pålsson LO, Hughes TR, Taube M, Kozak M, et al. A bacteriophage mimic of the bacterial nucleoid-associated protein Fis. The Biochemical Journal. PMID 32207815 DOI: 10.1042/BCJ20200146  0.01
2020 Schaich CL, Malaver D, Chen H, Shaltout HA, Zeki Al Hazzouri A, Herrington DM, Hughes TM. Association of Heart Rate Variability With Cognitive Performance: The Multi-Ethnic Study of Atherosclerosis. Journal of the American Heart Association. 9: e013827. PMID 32200711 DOI: 10.1161/JAHA.119.013827  0.01
2020 Akkouh IA, Ueland T, Hansson L, Inderhaug E, Hughes T, Eiel Steen N, Aukrust P, Andreassen OA, Szabo A, Djurovic S. Decreased IL-1β-induced CCL20 response in human iPSC-astrocytes in schizophrenia: potential attenuating effects on recruitment of regulatory T cells. Brain, Behavior, and Immunity. PMID 32109548 DOI: 10.1016/j.bbi.2020.02.008  0.01
2020 Shanmuganathan N, Hughes TP. What's NEXT for CML-NGS mutation screening. Blood. 135: 515-516. PMID 32078686 DOI: 10.1182/blood.2019004559  0.01
2020 Thomson DW, Shahrin NH, Wang PPS, Wadham C, Shanmuganathan N, Scott HS, Dinger ME, Hughes TP, Schreiber AW, Branford S. Aberrant RAG-mediated recombination contributes to multiple structural rearrangements in lymphoid blast crisis of chronic myeloid leukemia. Leukemia. PMID 32076119 DOI: 10.1038/s41375-020-0751-y  0.01
2019 Gottesman RF, Mosley TH, Knopman DS, Hao Q, Wong D, Wagenknecht LE, Hughes TM, Qiao Y, Dearborn J, Wasserman BA. Association of Intracranial Atherosclerotic Disease With Brain β-Amyloid Deposition: Secondary Analysis of the ARIC Study. Jama Neurology. PMID 31860001 DOI: 10.1001/jamaneurol.2019.4339  0.01
2019 Hughes TP, Mauro MJ, Cortes JE, Minami H, Rea D, DeAngelo DJ, Breccia M, Goh YT, Talpaz M, Hochhaus A, le Coutre P, Ottmann O, Heinrich MC, Steegmann JL, Deininger MWN, et al. Asciminib in Chronic Myeloid Leukemia after ABL Kinase Inhibitor Failure. The New England Journal of Medicine. 381: 2315-2326. PMID 31826340 DOI: 10.1056/NEJMoa1902328  0.01
2019 Tavakoli Shirazi P, Eadie LN, Heatley SL, Hughes TP, Yeung DT, White DL. The effect of co-occurring lesions on leukaemogenesis and drug response in T-ALL and ETP-ALL. British Journal of Cancer. PMID 31792348 DOI: 10.1038/s41416-019-0647-7  0.01
2019 Pagani IS, Dang P, Saunders VA, Grose R, Shanmuganathan N, Kok CH, Carne L, Rwodzi Z, Watts S, McLean J, Braley J, Altamura H, Yeung DT, Branford S, Yong ASM, ... ... Hughes TP, et al. Lineage of measurable residual disease in patients with chronic myeloid leukemia in treatment-free remission. Leukemia. PMID 31768016 DOI: 10.1038/s41375-019-0647-x  0.01
2019 Shanmuganathan N, Hughes TP. Early Management of CML. Current Hematologic Malignancy Reports. PMID 31701368 DOI: 10.1007/s11899-019-00550-8  0.01
2019 Akkouh IA, Skrede S, Holmgren A, Ersland KM, Hansson L, Bahrami S, Andreassen OA, Steen VM, Djurovic S, Hughes T. Exploring lithium's transcriptional mechanisms of action in bipolar disorder: a multi-step study. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31652432 DOI: 10.1038/s41386-019-0556-8  0.01
2019 Chirinos JA, Segers P, Hughes T, Townsend R. Large-Artery Stiffness in Health and Disease: JACC State-of-the-Art Review. Journal of the American College of Cardiology. 74: 1237-1263. PMID 31466622 DOI: 10.1016/j.jacc.2019.07.012  0.01
2019 Lim DJ, Ambale-Ventakesh B, Ostovaneh MR, Zghaib T, Ashikaga H, Wu C, Watson KE, Hughes T, Shea S, Heckbert SR, Bluemke DA, Post WS, Lima JAC. Change in left atrial function predicts incident atrial fibrillation: the Multi-Ethnic Study of Atherosclerosis. European Heart Journal Cardiovascular Imaging. PMID 31356656 DOI: 10.1093/ehjci/jez176  0.01
2019 Heraud C, Basuki J, Hughes TC, Mueller M. Copolymerization of Pentafluorophenylmethacrylate with Hydrophilic Methacrylamide Monomers Induces Premature Hydrolytic Cleavage. Macromolecular Rapid Communications. e1900278. PMID 31328341 DOI: 10.1002/marc.201900278  0.01
2019 Branford S, Kim DDH, Apperley JF, Eide CA, Mustjoki S, Ong ST, Nteliopoulos G, Ernst T, Chuah C, Gambacorti-Passerini C, Mauro MJ, Druker BJ, Kim DW, Mahon FX, Cortes J, ... ... Hughes TP, et al. Laying the foundation for genomically-based risk assessment in chronic myeloid leukemia. Leukemia. PMID 31209280 DOI: 10.1038/s41375-019-0512-y  0.01
2019 Lambert SA, Yang AWH, Sasse A, Cowley G, Albu M, Caddick MX, Morris QD, Weirauch MT, Hughes TR. Similarity regression predicts evolution of transcription factor sequence specificity. Nature Genetics. PMID 31133749 DOI: 10.1038/s41588-019-0411-1  0.01
2019 Kok CH, Yeung DT, Lu L, Watkins DB, Leclercq TM, Dang P, Saunders VA, Reynolds J, White DL, Hughes TP. Gene expression signature that predicts early molecular response failure in chronic-phase CML patients on frontline imatinib. Blood Advances. 3: 1610-1621. PMID 31126916 DOI: 10.1182/bloodadvances.2019000195  0.01
2019 Dipietro L, Campbell WW, Buchner DM, Erickson KI, Powell KE, Bloodgood B, Hughes T, Day KR, Piercy KL, Vaux-Bjerke A, Olson RD. Physical Activity, Injurious Falls, and Physical Function in Aging: An Umbrella Review. Medicine and Science in Sports and Exercise. 51: 1303-1313. PMID 31095087 DOI: 10.1249/MSS.0000000000001942  0.01
2019 Hughes T, Simon GP, Saito K. Light-Healable Epoxy Polymer Networks via Anthracene Dimer Scission of Diamine Crosslinker. Acs Applied Materials & Interfaces. PMID 31062582 DOI: 10.1021/acsami.9b02521  0.01
2019 Alber J, Alladi S, Bae HJ, Barton DA, Beckett LA, Bell JM, Berman SE, Biessels GJ, Black SE, Bos I, Bowman GL, Brai E, Brickman AM, Callahan BL, Corriveau RA, ... ... Hughes TM, et al. White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): Knowledge gaps and opportunities. Alzheimer's & Dementia (New York, N. Y.). 5: 107-117. PMID 31011621 DOI: 10.1016/j.trci.2019.02.001  0.01
2019 Shanmuganathan N, Braley JA, Yong AS, Hiwase DK, Yeung DT, Ross DM, Hughes TP, Branford S. Modelling the safe minimum frequency of molecular monitoring for CML patients attempting treatment-free remission. Blood. PMID 30967368 DOI: 10.1182/blood.2019000120  0.01
2019 Ross DM, Pagani IS, Irani YD, Clarson J, Leclercq T, Dang P, McLean J, Saunders VA, Carne L, Reynolds J, Ritchie DS, White DL, Branford S, Hughes TP, Yong ASM. Lenalidomide maintenance treatment after imatinib discontinuation: results of a phase 1 clinical trial in chronic myeloid leukaemia. British Journal of Haematology. PMID 30916385 DOI: 10.1111/bjh.15894  0.01
2019 Chhetri R, Wee LYA, Sinha R, Kutyna MM, Pham A, Stathopoulos H, Nath L, Nath SV, Wickham N, Hughes T, Singhal D, Roxby DJ, Hiwase DK. Red cell autoimmunization and alloimmunization in myelodysplastic syndromes: prevalence, characteristic and significance. Haematologica. PMID 30819906 DOI: 10.3324/haematol.2018.215087  0.01
2019 Shanmuganathan N, Branford S, Hughes TP, Hiwase D. Bone marrow fibrosis associated with long-term imatinib therapy: resolution after switching to a second-generation TKI. Blood Advances. 3: 370-374. PMID 30723111 DOI: 10.1182/bloodadvances.2018027516  0.01
2019 Magomedova L, Tiefenbach J, Zilberman E, Le Billan F, Voisin V, Saikali M, Boivin V, Robitaille M, Gueroussov S, Irimia M, Ray D, Patel R, Xu C, Jeyasuria P, Bader GD, ... Hughes TR, et al. ARGLU1 is a transcriptional coactivator and splicing regulator important for stress hormone signaling and development. Nucleic Acids Research. PMID 30698747 DOI: 10.1093/nar/gkz010  0.01
2019 Sweeney MD, Montagne A, Sagare AP, Nation DA, Schneider LS, Chui HC, Harrington MG, Pa J, Law M, Wang DJJ, Jacobs RE, Doubal FN, Ramirez J, Black SE, Nedergaard M, ... Hughes TM, et al. Vascular dysfunction-The disregarded partner of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 15: 158-167. PMID 30642436 DOI: 10.1016/j.jalz.2018.07.222  0.01
2018 Ray P, Hughes T, Smith C, Simon GP, Saito K. Synthesis of Bioacrylic Polymers from Dihydro-5-hydroxyl furan-2-one (2H-HBO) by Free and Controlled Radical Polymerization. Acs Omega. 3: 2040-2048. PMID 31458513 DOI: 10.1021/acsomega.7b01929  0.01
2018 Witoelar A, Rongve A, Almdahl IS, Ulstein ID, Engvig A, White LR, Selbæk G, Stordal E, Andersen F, Brækhus A, Saltvedt I, Engedal K, Hughes T, Bergh S, Bråthen G, et al. Meta-analysis of Alzheimer's disease on 9,751 samples from Norway and IGAP study identifies four risk loci. Scientific Reports. 8: 18088. PMID 30591712 DOI: 10.1038/s41598-018-36429-6  0.01
2018 Davis GM, Tu S, Anderson JWT, Colson RN, Gunzburg MJ, Francisco MA, Ray D, Shrubsole SP, Sobotka JA, Seroussi U, Lao RX, Maity T, Wu MZ, McJunkin K, Morris QD, ... Hughes TR, et al. The TRIM-NHL protein NHL-2 is a co-factor in the nuclear and somatic RNAi pathways in . Elife. 7. PMID 30575518 DOI: 10.7554/eLife.35478  0.01
2018 Shanmuganathan N, Hughes TP. Molecular monitoring in CML: how deep? How often? How should it influence therapy? Hematology. American Society of Hematology. Education Program. 2018: 168-176. PMID 30504306 DOI: 10.1182/asheducation-2018.1.168  0.01
2018 Tvorogov D, Thomas D, Liau NPD, Dottore M, Barry EF, Lathi M, Kan WL, Hercus TR, Stomski F, Hughes TP, Tergaonkar V, Parker MW, Ross DM, Majeti R, Babon JJ, et al. Accumulation of JAK activation loop phosphorylation is linked to type I JAK inhibitor withdrawal syndrome in myelofibrosis. Science Advances. 4: eaat3834. PMID 30498775 DOI: 10.1126/sciadv.aat3834  0.01
2018 Buckley MA, Woods NT, Tyrer JP, Mendoza-Fandiño G, Lawrenson K, Hazelett DJ, Najafabadi HS, Gjyshi A, Carvalho RS, Lyra PC, Coetzee SG, Shen HC, Yang AW, Earp MA, Yoder S, ... ... Hughes TR, et al. Functional analysis and fine mapping of the 9p22.2 ovarian cancer susceptibility locus. Cancer Research. PMID 30487138 DOI: 10.1158/0008-5472.CAN-17-3864  0.01
2018 Shanmuganathan N, Hughes TP. Molecular monitoring in CML: How deep? How often? How should it influence therapy? Blood. PMID 30429156 DOI: 10.1182/blood-2018-05-848630  0.01
2018 Lu L, Kok CH, Saunders VA, Wang J, McLean JA, Hughes TP, White DL. Modelling ponatinib resistance in tyrosine kinase inhibitor-naïve and dasatinib resistant + cell lines. Oncotarget. 9: 34735-34747. PMID 30410673 DOI: 10.18632/oncotarget.26187  0.01
2018 Laverty KU, Stout JM, Sullivan MJ, Shah H, Gill N, Holbrook L, Deikus G, Sebra R, Hughes TR, Page JE, van Bakel H. A physical and genetic map of identifies extensive rearrangement at the THC/CBD acid synthase locus. Genome Research. PMID 30409771 DOI: 10.1101/gr.242594.118  0.01
2018 Mahapatra G, Smith SC, Hughes TM, Wagner B, Maldjian JA, Freedman BI, Molina AJA. Blood-based bioenergetic profiling is related to differences in brain morphology in African Americans with Type 2 diabetes. Clinical Science (London, England : 1979). PMID 30401689 DOI: 10.1042/CS20180690  0.01
2018 Walker KA, Windham BG, Brown CH, Knopman DS, Jack CR, Mosley TH, Selvin E, Wong DF, Hughes TM, Zhou Y, Gross AL, Gottesman RF. The Association of Mid- and Late-Life Systemic Inflammation with Brain Amyloid Deposition: The ARIC-PET Study. Journal of Alzheimer's Disease : Jad. PMID 30400093 DOI: 10.3233/JAD-180469  0.01
2018 Koch M, DeKosky ST, Fitzpatrick AL, Furtado JD, Lopez OL, Kuller LH, Mackey RH, Hughes TM, Mukamal KJ, Jensen MK. Apolipoproteins and Alzheimer's pathophysiology. Alzheimer's & Dementia (Amsterdam, Netherlands). 10: 545-553. PMID 30370330 DOI: 10.1016/j.dadm.2018.07.001  0.01
2018 Ross DM, Pagani IS, Shanmuganathan N, Kok CH, Seymour JF, Mills AK, Filshie RJ, Arthur CK, Dang P, Saunders VA, Braley J, Yong AS, Yeung DT, White DL, Grigg AP, ... ... Hughes TP, et al. Long-term treatment-free remission of chronic myeloid leukemia with falling levels of residual leukemic cells. Leukemia. PMID 30315232 DOI: 10.1038/s41375-018-0264-0  0.01
2018 Hughes T, Sønderby IE, Polushina T, Hansson L, Holmgren A, Athanasiu L, Melbø-Jørgensen C, Hassani S, Hoeffding LK, Herms S, Bergen SE, Karlsson R, Song J, Rietschel M, Nöthen MM, et al. Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder. Translational Psychiatry. 8: 210. PMID 30297702 DOI: 10.1038/s41398-018-0175-x  0.01
2018 Lambert SA, Jolma A, Campitelli LF, Das PK, Yin Y, Albu M, Chen X, Taipale J, Hughes TR, Weirauch MT. The Human Transcription Factors. Cell. 175: 598-599. PMID 30290144 DOI: 10.1016/j.cell.2018.09.045  0.01
2018 Mahon FX, Hughes TP. Treatment-Free Remission After Second-Line Nilotinib Treatment. Annals of Internal Medicine. 169: 510. PMID 30285197 DOI: 10.7326/L18-0431  0.01
2018 Duan B, Ding P, Hughes TR, Navarre WW, Liu J, Xia B. How bacterial xenogeneic silencer rok distinguishes foreign from self DNA in its resident genome. Nucleic Acids Research. PMID 30252102 DOI: 10.1093/nar/gky836  0.01
2018 Sasse A, Laverty KU, Hughes TR, Morris QD. Motif models for RNA-binding proteins. Current Opinion in Structural Biology. 53: 115-123. PMID 30172081 DOI: 10.1016/j.sbi.2018.08.001  0.01
2018 Francois-Moutal L, Jahanbakhsh S, Nelson A, Ray D, Scott DD, Hennefarth M, Moutal A, Perez-Miller S, Ambrose AJ, Al-Shamari A, Coursodon P, Meechoovet B, Reiman R, Lyons E, Beilstein M, ... ... Hughes TR, et al. A Chemical Biology Approach to Model Pontocerebellar Hypoplasia Type 1B (PCH1B). Acs Chemical Biology. PMID 30141626 DOI: 10.1021/acschembio.8b00745  0.01
2018 Akkouh IA, Ueland T, Andreassen OA, Brattbakk HR, Steen VM, Hughes T, Djurovic S. Expression of TCN1 in Blood is Negatively Associated with Verbal Declarative Memory Performance. Scientific Reports. 8: 12654. PMID 30139959 DOI: 10.1038/s41598-018-30898-5  0.01
2018 Hughes TP, Laneuville P, Rousselot P, Snyder DS, Rea D, Shah NP, Paar D, Abruzzese E, Hochhaus A, Lipton JH, Cortes JE. Incidence, outcomes, and risk factors of pleural effusion in patients receiving dasatinib therapy for Philadelphia chromosome-positive leukemia. Haematologica. PMID 30093398 DOI: 10.3324/haematol.2018.188987  0.01
2018 Rawlings AM, Juraschek SP, Heiss G, Hughes T, Meyer ML, Selvin E, Sharrett AR, Windham BG, Gottesman RF. Association of orthostatic hypotension with incident dementia, stroke, and cognitive decline. Neurology. PMID 30045960 DOI: 10.1212/WNL.0000000000006027  0.01
2018 Hughes TM, Sink KM, Williamson JD, Hugenschmidt CE, Wagner BC, Whitlow CT, Xu J, Smith SC, Launer LJ, Barzilay JI, Ismail-Beigi F, Bryan RN, Hsu FC, Bowden DW, Maldjian JA, et al. Relationships between cerebral structure and cognitive function in African Americans with type 2 diabetes. Journal of Diabetes and Its Complications. PMID 30042057 DOI: 10.1016/j.jdiacomp.2018.05.017  0.01
2018 Pagani IS, Dang P, Kommers IO, Goyne JM, Nicola M, Saunders VA, Braley J, White DL, Yeung DT, Branford S, Hughes TP, Ross DM. BCR-ABL1 genomic DNA PCR response kinetics during first-line imatinib treatment of chronic myeloid leukemia. Haematologica. PMID 29976745 DOI: 10.3324/haematol.2018.189787  0.01
2018 Branford S, Wang P, Yeung DT, Thomson D, Purins A, Wadham C, Shahrin NH, Marum JE, Nataren N, Parker WT, Geoghegan J, Feng J, Shanmuganathan N, Mueller MC, Dietz C, ... ... Hughes TP, et al. Integrative genomic analysis reveals cancer-associated mutations at diagnosis of CML in patients with high risk disease. Blood. PMID 29967129 DOI: 10.1182/blood-2018-02-832253  0.01
2018 Ross DM, Burbury KL, Grigg AP, Hughes TP, Seymour JF. Management of Pregnancy in Women With Chronic Myeloid Leukemia. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2018786137. PMID 29851544 DOI: 10.1200/JCO.2018.78.6137  0.01
2018 Nair SS, Luu PL, Qu W, Maddugoda M, Huschtscha L, Reddel R, Chenevix-Trench G, Toso M, Kench JG, Horvath LG, Hayes VM, Stricker PD, Hughes TP, White DL, Rasko JEJ, et al. Guidelines for whole genome bisulphite sequencing of intact and FFPET DNA on the Illumina HiSeq X Ten. Epigenetics & Chromatin. 11: 24. PMID 29807544 DOI: 10.1186/s13072-018-0194-0  0.01
2018 Boni AC, Ambrósio DL, Cupertino FB, Montenegro-Montero A, Virgilio S, Freitas FZ, Corrocher FA, Gonçalves RD, Yang A, Weirauch MT, Hughes TR, Larrondo LF, Bertolini MC. Neurospora crassa developmental control mediated by the FLB-3 transcription factor. Fungal Biology. 122: 570-582. PMID 29801802 DOI: 10.1016/j.funbio.2018.01.004  0.01
2018 Eadie LN, Hughes TP, White DL. Patients with low OCT-1 activity and high ABCB1 fold rise have poor long-term outcomes in response to tyrosine kinase inhibitor therapy. Leukemia. PMID 29654270 DOI: 10.1038/s41375-018-0101-5  0.01
2018 Li L, Lu C, Wang L, Chen M, White JF, Hao X, McLean KM, Chen H, Hughes TC. Gelatin-based photo curable hydrogels for corneal wound repair. Acs Applied Materials & Interfaces. PMID 29620862 DOI: 10.1021/acsami.7b17054  0.01
2018 Ong KL, Morris MJ, McClelland RL, Hughes TM, Maniam J, Fitzpatrick AL, Martin SS, Luchsinger JA, Rapp SR, Hayden KM, Sandfort V, Allison MA, Rye KA. Relationship of Lipids and Lipid-Lowering Medications With Cognitive Function: The Multi-Ethnic Study of Atherosclerosis. American Journal of Epidemiology. 187: 767-776. PMID 29617947 DOI: 10.1093/aje/kwx329  0.01
2018 Segorbe D, Wilkinson D, Mizeranschi A, Hughes T, Aaløkken R, Vachova L, Palkova Z, Gilfillan GD. An optimized FAIRE procedure for low cell numbers in yeast. Yeast (Chichester, England). PMID 29577419 DOI: 10.1002/yea.3316  0.01
2018 Eadie LN, Saunders VA, Branford S, White DL, Hughes TP. The new allosteric inhibitor asciminib is susceptible to resistance mediated by ABCB1 and ABCG2 overexpression. Oncotarget. 9: 13423-13437. PMID 29568367 DOI: 10.18632/oncotarget.24393  0.01
2018 Liu K, Xu C, Lei M, Yang A, Loppnau P, Hughes TR, Min J. Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA. The Journal of Biological Chemistry. PMID 29567833 DOI: 10.1074/jbc.RA118.001785  0.01
2018 Cortes JE, Kim DW, Pinilla-Ibarz J, le Coutre PD, Paquette R, Chuah C, Nicolini FE, Apperley JF, Khoury HJ, Talpaz M, DeAngelo DJ, Abruzzese E, Rea D, Baccarani M, Müller MC, ... ... Hughes TP, et al. Ponatinib efficacy and safety in Philadelphia chromosome-positive leukemia: final 5-year results of the phase 2 PACE trial. Blood. PMID 29567798 DOI: 10.1182/blood-2016-09-739086  0.01
2018 Hughes TM, Wagenknecht LE, Craft S, Mintz A, Heiss G, Palta P, Wong D, Zhou Y, Knopman D, Mosley TH, Gottesman RF. Arterial stiffness and dementia pathology: Atherosclerosis Risk in Communities (ARIC)-PET Study. Neurology. PMID 29549223 DOI: 10.1212/WNL.0000000000005259  0.01
2018 Whinton M, Hughes TC, Peng S, Brook MA. Silicone Microemulsion Structures Are Maintained During Polymerization with Reactive Surfactants. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 29546990 DOI: 10.1021/acs.langmuir.8b00240  0.01
2018 McClure BJ, Heatley SL, Kok CH, Sadras T, An J, Hughes TP, Lock RB, Yeung D, Sutton R, White DL. Pre-B acute lymphoblastic leukaemia recurrent fusion, EP300-ZNF384, is associated with a distinct gene expression. British Journal of Cancer. PMID 29531323 DOI: 10.1038/s41416-018-0022-0  0.01
2018 Hiwase D, Tan P, D'Rozario J, Taper J, Powell A, Irving I, Wright M, Branford S, Yeung DT, Anderson L, Gervasio O, Levetan C, Roberts W, Solterbeck A, Traficante R, ... Hughes T, et al. Efficacy and safety of nilotinib 300 mg twice daily in patients with chronic myeloid leukemia in chronic phase who are intolerant to prior tyrosine kinase inhibitors: Results from the Phase IIIb ENESTswift study. Leukemia Research. 67: 109-115. PMID 29494928 DOI: 10.1016/j.leukres.2018.02.013  0.01
2018 Fan L, Martynenko A, Doucette C, Hughes T, Fillmore S. Microbial Quality and Shelf Life of Blueberry Purée Developed Using Cavitation Technology. Journal of Food Science. PMID 29469934 DOI: 10.1111/1750-3841.14073  0.01
2018 Mahon FX, Boquimpani C, Kim DW, Benyamini N, Clementino NCD, Shuvaev V, Ailawadhi S, Lipton JH, Turkina AG, De Paz R, Moiraghi B, Nicolini FE, Dengler J, Sacha T, Takahashi N, ... Hughes TP, et al. Treatment-Free Remission After Second-Line Nilotinib Treatment in Patients With Chronic Myeloid Leukemia in Chronic Phase: Results From a Single-Group, Phase 2, Open-Label Study. Annals of Internal Medicine. PMID 29459949 DOI: 10.7326/M17-1094  0.01
2018 Lambert SA, Jolma A, Campitelli LF, Das PK, Yin Y, Albu M, Chen X, Taipale J, Hughes TR, Weirauch MT. The Human Transcription Factors. Cell. 172: 650-665. PMID 29425488 DOI: 10.1016/j.cell.2018.01.029  0.01
2018 Eadie LN, Dang P, Goyne JM, Hughes TP, White DL. ABCC6 plays a significant role in the transport of nilotinib and dasatinib, and contributes to TKI resistance in vitro, in both cell lines and primary patient mononuclear cells. Plos One. 13: e0192180. PMID 29385210 DOI: 10.1371/journal.pone.0192180  0.01
2018 Moazzami K, Ostovaneh MR, Ambale Venkatesh B, Habibi M, Yoneyama K, Wu C, Liu K, Pimenta I, Fitzpatrick A, Shea S, McClelland RL, Heckbert S, Gottesman RF, Bluemke DA, Hughes TM, et al. Left Ventricular Hypertrophy and Remodeling and Risk of Cognitive Impairment and Dementia: MESA (Multi-Ethnic Study of Atherosclerosis). Hypertension (Dallas, Tex. : 1979). PMID 29378853 DOI: 10.1161/HYPERTENSIONAHA.117.10289  0.01
2018 Broughton SE, Hercus TR, Nero TL, Kan WL, Barry EF, Dottore M, Cheung Tung Shing KS, Morton CJ, Dhagat U, Hardy MP, Wilson NJ, Downton MT, Schieber C, Hughes TP, Lopez AF, et al. A dual role for the N-terminal domain of the IL-3 receptor in cell signalling. Nature Communications. 9: 386. PMID 29374162 DOI: 10.1038/s41467-017-02633-7  0.01
2018 Hsu FC, Sink KM, Hugenschmidt CE, Williamson JD, Hughes TM, Palmer ND, Xu J, Smith SC, Wagner BC, Whitlow CT, Bowden DW, Maldjian JA, Divers J, Freedman BI. Cerebral structure and cognitive performance in African Americans and European Americans with type 2 diabetes. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 29309525 DOI: 10.1093/gerona/glx255  0.01
2018 Xu C, Liu K, Lei M, Yang A, Li Y, Hughes TR, Min J. DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants. Structure (London, England : 1993). 26: 85-95.e3. PMID 29276034 DOI: 10.1016/j.str.2017.11.022  0.01
2017 Ge C, Basuki JS, White J, Hou R, Peng Y, Hughes TC, Tan T. Photothermal triggered protein release from an injectable polycaprolactone-based microspherical depot. Journal of Materials Chemistry. B. 5: 3634-3639. PMID 32264051 DOI: 10.1039/c7tb00837f  0.01
2017 Marum JE, Yeung DT, Purins L, Reynolds J, Parker WT, Stangl D, Wang PPS, Price DJ, Tuke J, Schreiber AW, Scott HS, Hughes TP, Branford S. ASXL1 and BIM germ line variants predict response and identify CML patients with the greatest risk of imatinib failure. Blood Advances. 1: 1369-1381. PMID 29296778 DOI: 10.1182/bloodadvances.2017006825  0.01
2017 Townsend PD, Dixon CH, Slootweg EJ, Sukarta OC, Yang AW, Hughes TR, Sharples GJ, Palsson LO, Takken FLW, Goverse A, Cann MJ. The intracellular immune receptor Rx1 regulates the DNA-binding activity of a Golden2-like transcription factor. The Journal of Biological Chemistry. PMID 29217772 DOI: 10.1074/jbc.RA117.000485  0.01
2017 Townsend PD, Dixon CH, Slootweg EJ, Sukarta OC, Yang AW, Hughes TR, Sharples GJ, Palsson LO, Takken FLW, Goverse A, Cann MJ. The intracellular immune receptor Rx1 regulates the DNA-binding activity of a Golden2-like transcription factor. The Journal of Biological Chemistry. PMID 29217772 DOI: 10.1074/jbc.RA117.000485  0.01
2017 Boshra H, Zelek WM, Hughes TR, Rodriguez de Cordoba S, Morgan BP. Absence of CD59 in Guinea Pigs: Analysis of the Cavia porcellus Genome Suggests the Evolution of a CD59 Pseudogene. Journal of Immunology (Baltimore, Md. : 1950). PMID 29167230 DOI: 10.4049/jimmunol.1701238  0.01
2017 Boshra H, Zelek WM, Hughes TR, Rodriguez de Cordoba S, Morgan BP. Absence of CD59 in Guinea Pigs: Analysis of the Cavia porcellus Genome Suggests the Evolution of a CD59 Pseudogene. Journal of Immunology (Baltimore, Md. : 1950). PMID 29167230 DOI: 10.4049/jimmunol.1701238  0.01
2017 Rasko JEJ, Hughes TP. First Approved Kinase Inhibitor for AML. Cell. 171: 981. PMID 29149610 DOI: 10.1016/j.cell.2017.11.007  0.01
2017 Barazandeh M, Lambert S, Albu M, Hughes TR. Comparison of ChIP-seq Data and a Reference Motif Set for Human KRAB C2H2 Zinc Finger Proteins. G3 (Bethesda, Md.). PMID 29146583 DOI: 10.1534/g3.117.300296  0.01
2017 Barrett EJ, Liu Z, Khamaisi M, King GL, Klein R, Klein BEK, Hughes TM, Craft S, Freedman BI, Bowden DW, Vinik AI, Casellini CM. Diabetic Microvascular Disease: An Endocrine Society Scientific Statement. The Journal of Clinical Endocrinology and Metabolism. PMID 29126250 DOI: 10.1210/jc.2017-01922  0.01
2017 Maršíková J, Wilkinson D, Hlaváček O, Gilfillan GD, Mizeranschi A, Hughes T, Begany M, Rešetárová S, Váchová L, Palková Z. Metabolic differentiation of surface and invasive cells of yeast colony biofilms revealed by gene expression profiling. Bmc Genomics. 18: 814. PMID 29061122 DOI: 10.1186/s12864-017-4214-4  0.01
2017 Hughes TM, Lockhart SN, Smagula SF. Blood Pressure's Role in Alzheimer Disease Pathology. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. PMID 29050913 DOI: 10.1016/j.jagp.2017.09.019  0.01
2017 Sadras T, Heatley SL, Kok CH, McClure BJ, Yeung D, Hughes TP, Sutton R, Ziegler DS, White DL. A novel somatic JAK2 kinase-domain mutation in pediatric acute lymphoblastic leukemia with rapid on-treatment development of LOH. Cancer Genetics. 216: 86-90. PMID 29025600 DOI: 10.1016/j.cancergen.2017.07.008  0.01
2017 Heatley SL, Sadras T, Kok CH, Nievergall E, Quek K, Dang P, McClure B, Venn N, Moore S, Suttle J, Law T, Ng A, Muskovic W, Norris MD, Revesz T, ... ... Hughes TP, et al. High prevalence of relapse in children with Philadelphia-like acute lymphoblastic leukemia despite risk-adapted treatment. Haematologica. PMID 28935844 DOI: 10.3324/haematol.2016.162925  0.01
2017 Najafabadi HS, Garton M, Weirauch MT, Mnaimneh S, Yang A, Kim PM, Hughes TR. Non-base-contacting residues enable kaleidoscopic evolution of metazoan C2H2 zinc finger DNA binding. Genome Biology. 18: 167. PMID 28877740 DOI: 10.1186/s13059-017-1287-y  0.01
2017 Sadras T, Heatley SL, Kok CH, Dang P, Galbraith KM, McClure BJ, Muskovic W, Venn NC, Moore S, Osborn M, Revesz T, Moore AS, Hughes TP, Yeung D, Sutton R, et al. Differential expression of MUC4, GPR110 and IL2RA defines two groups of CRLF2-rearranged acute lymphoblastic leukemia patients with distinct secondary lesions. Cancer Letters. PMID 28866095 DOI: 10.1016/j.canlet.2017.08.034  0.01
2017 Solingapuram Sai KK, Donald Gage H, Almaguel F, Neth B, Hughes TM, Tremblay S, Castellano CA, Cunnane SC, Jorgensen MJ, Craft S, Mintz A. Automated synthesis of 1-[(11)C]acetoacetate on a TRASIS AIO module. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 129: 57-61. PMID 28806598 DOI: 10.1016/j.apradiso.2017.07.066  0.01
2017 Rasmussen HB, Madsen MB, Lyauk YK, Hansen PR, Hughes T. Carboxylesterase 1A2 encoding gene with increased transcription and potential rapid drug metabolism in Asian populations. Drug Metabolism and Personalized Therapy. PMID 28803225 DOI: 10.1515/dmpt-2017-0012  0.01
2017 Pagani IS, Kok CH, Saunders VA, Van der Hoek MB, Heatley SL, Schwarer AP, Hahn CN, Hughes TP, White DL, Ross DM. A Method for Next-Generation Sequencing of Paired Diagnostic and Remission Samples to Detect Mitochondrial DNA Mutations Associated with Leukemia. The Journal of Molecular Diagnostics : Jmd. PMID 28732215 DOI: 10.1016/j.jmoldx.2017.05.009  0.01
2017 Hercus TR, Kan WLT, Broughton SE, Tvorogov D, Ramshaw HS, Sandow JJ, Nero TL, Dhagat U, Thompson EJ, Shing KSCT, McKenzie DR, Wilson NJ, Owczarek CM, Vairo G, Nash AD, ... ... Hughes T, et al. Role of the β Common (βc) Family of Cytokines in Health and Disease. Cold Spring Harbor Perspectives in Biology. PMID 28716883 DOI: 10.1101/cshperspect.a028514  0.01
2017 Hughes TP, Munhoz E, Aurelio Salvino M, Ong TC, Elhaddad A, Shortt J, Quach H, Pavlovsky C, Louw VJ, Shih LY, Turkina AG, Meillon L, Jin Y, Acharya S, Dalal D, et al. Nilotinib dose-optimization in newly diagnosed chronic myeloid leukaemia in chronic phase: final results from ENESTxtnd. British Journal of Haematology. PMID 28699641 DOI: 10.1111/bjh.14829  0.01
2017 Dang H, Takai A, Forgues M, Pomyen Y, Mou H, Xue W, Ray D, Ha KCH, Morris QD, Hughes TR, Wang XW. Oncogenic Activation of the RNA Binding Protein NELFE and MYC Signaling in Hepatocellular Carcinoma. Cancer Cell. 32: 101-114.e8. PMID 28697339 DOI: 10.1016/j.ccell.2017.06.002  0.01
2017 Cook KB, Vembu S, Ha KCH, Zheng H, Laverty KU, Hughes TR, Ray D, Morris QD. RNAcompete-S: combined RNA sequence/structure preferences for RNA binding proteins derived from a single-step in vitro selection. Methods (San Diego, Calif.). PMID 28651966 DOI: 10.1016/j.ymeth.2017.06.024  0.01
2017 Freedman BI, Sink KM, Hugenschmidt CE, Hughes TM, Williamson JD, Whitlow CT, Palmer ND, Miller ME, Lovato LC, Xu J, Smith SC, Launer LJ, Barzilay JI, Cohen RM, Sullivan MD, et al. Associations of Early Kidney Disease With Brain Magnetic Resonance Imaging and Cognitive Function in African Americans With Type 2 Diabetes Mellitus. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. PMID 28648301 DOI: 10.1053/j.ajkd.2017.05.006  0.01
2017 Bergfeld A, Dasari P, Werner S, Hughes TR, Song WC, Hortschansky P, Brakhage AA, Hünig T, Zipfel PF, Beyersdorf N. Direct Binding of the pH-Regulated Protein 1 (Pra1) from Candida albicans Inhibits Cytokine Secretion by Mouse CD4(+) T Cells. Frontiers in Microbiology. 8: 844. PMID 28553273 DOI: 10.3389/fmicb.2017.00844  0.01
2017 Hughes TR, Lambert SA. Transcription factors read epigenetics. Science (New York, N.Y.). 356: 489-490. PMID 28473550 DOI: 10.1126/science.aan2927  0.01
2017 Hughes TM, Craft S, Baker LD, Espeland MA, Rapp SR, Sink KM, Bertoni AG, Burke GL, Gottesman RF, Michos ED, Luchsinger JA, Fitzpatrick AL, Hayden KM. Changes in metabolic risk factors over 10 years and their associations with late-life cognitive performance: The Multi-Ethnic Study of Atherosclerosis. Alzheimer's & Dementia (Amsterdam, Netherlands). 8: 18-25. PMID 28435852 DOI: 10.1016/j.dadm.2017.03.003  0.01
2017 Nicolini FE, Basak GW, Kim DW, Olavarria E, Pinilla-Ibarz J, Apperley JF, Hughes T, Niederwieser D, Mauro MJ, Chuah C, Hochhaus A, Martinelli G, DerSarkissian M, Duh MS, McGarry LJ, et al. Overall survival with ponatinib versus allogeneic stem cell transplantation in Philadelphia chromosome-positive leukemias with the T315I mutation. Cancer. PMID 28387926 DOI: 10.1002/cncr.30558  0.01
2017 Wylie AA, Schoepfer J, Jahnke W, Cowan-Jacob SW, Loo A, Furet P, Marzinzik AL, Pelle X, Donovan J, Zhu W, Buonamici S, Hassan AQ, Lombardo F, Iyer V, Palmer M, ... ... Hughes TP, et al. The allosteric inhibitor ABL001 enables dual targeting of BCR-ABL1. Nature. PMID 28329763 DOI: 10.1038/nature21702  0.01
2017 Granados-Durán P, López-Ávalos MD, Cifuentes M, Pérez-Martín M, Fernández-Arjona MD, Hughes TR, Johnson K, Morgan BP, Fernández-Llebrez P, Grondona JM. Microbial Neuraminidase Induces a Moderate and Transient Myelin Vacuolation Independent of Complement System Activation. Frontiers in Neurology. 8: 78. PMID 28326060 DOI: 10.3389/fneur.2017.00078  0.01
2017 Hochhaus A, Larson RA, Guilhot F, Radich JP, Branford S, Hughes TP, Baccarani M, Deininger MW, Cervantes F, Fujihara S, Ortmann CE, Menssen HD, Kantarjian H, O'Brien SG, Druker BJ, et al. Long-Term Outcomes of Imatinib Treatment for Chronic Myeloid Leukemia. The New England Journal of Medicine. 376: 917-927. PMID 28273028 DOI: 10.1056/NEJMoa1609324  0.01
2017 Hughes TP, Ross DM. Targeted therapies: Remembrance of things past - discontinuation of second-generation TKI therapy for CML. Nature Reviews. Clinical Oncology. PMID 28169304 DOI: 10.1038/nrclinonc.2017.11  0.01
2017 Han H, Braunschweig U, Gonatopoulos-Pournatzis T, Weatheritt RJ, Hirsch CL, Ha KC, Radovani E, Nabeel-Shah S, Sterne-Weiler T, Wang J, O'Hanlon D, Pan Q, Ray D, Zheng H, Vizeacoumar F, ... ... Hughes TR, et al. Multilayered Control of Alternative Splicing Regulatory Networks by Transcription Factors. Molecular Cell. 65: 539-553.e7. PMID 28157508 DOI: 10.1016/j.molcel.2017.01.011  0.01
2017 Wang J, Lu L, Kok CH, Saunders VA, Goyne JM, Dang P, Leclercq TM, Hughes TP, White DL. Increased peroxisome proliferator-activated receptor-gamma activity reduces imatinib uptake and efficacy in chronic myeloid leukemia mononuclear cells. Haematologica. PMID 28154092 DOI: 10.3324/haematol.2016.153270  0.01
2017 Hughes A, Clarson J, Gargett T, Yu W, Brown MP, Lopez AF, Hughes TP, Yong AS. Comment on "KB004, a first in class monoclonal antibody targeting the receptor tyrosine kinase EphA3, in patients with advanced hematologic malignancies: Results from a phase 1 study". Leukemia Research. 55: 55-57. PMID 28129558 DOI: 10.1016/j.leukres.2017.01.009  0.01
2017 Sopper S, Mustjoki S, White D, Hughes T, Valent P, Burchert A, Gjertsen BT, Gastl G, Baldauf M, Trajanoski Z, Giles F, Hochhaus A, Ernst T, Schenk T, Janssen JJ, et al. Reduced CD62L Expression on T Cells and Increased Soluble CD62L Levels Predict Molecular Response to Tyrosine Kinase Inhibitor Therapy in Early Chronic-Phase Chronic Myelogenous Leukemia. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 35: 175-184. PMID 28056193 DOI: 10.1200/JCO.2016.67.0893  0.01
2017 Hughes A, Clarson J, Tang C, Vidovic L, White DL, Hughes TP, Yong AS. CML patients with deep molecular responses to TKI have restored immune effectors, decreased PD-1 and immune suppressors. Blood. PMID 28049640 DOI: 10.1182/blood-2016-10-745992  0.01
2017 Banjar H, Ranasinghe D, Brown F, Adelson D, Kroger T, Leclercq T, White D, Hughes T, Chaudhri N. Modelling Predictors of Molecular Response to Frontline Imatinib for Patients with Chronic Myeloid Leukaemia. Plos One. 12: e0168947. PMID 28045960 DOI: 10.1371/journal.pone.0168947  0.01
2016 Barratt DT, Cox HK, Menelaou A, Yeung DT, White DL, Hughes TP, Somogyi AA. CYP2C8 Genotype Significantly Alters Imatinib Metabolism in Chronic Myeloid Leukaemia Patients. Clinical Pharmacokinetics. PMID 27995529 DOI: 10.1007/s40262-016-0494-0  0.01
2016 Ray D, C H Ha K, Nie K, Zheng H, Hughes TR, Morris QD. RNAcompete methodology and application to determine sequence preferences of unconventional RNA-binding proteins. Methods (San Diego, Calif.). PMID 27956239 DOI: 10.1016/j.ymeth.2016.12.003  0.01
2016 Basuki JS, Qie F, Mulet X, Suryadinata R, Vashi AV, Peng YY, Li L, Hao X, Tan T, Hughes TC. Photo-Modulated Therapeutic Protein Release from a Hydrogel Depot Using Visible Light. Angewandte Chemie (International Ed. in English). PMID 27918129 DOI: 10.1002/anie.201610618  0.01
2016 van der Does HC, Fokkens L, Yang A, Schmidt SM, Langereis L, Lukasiewicz JM, Hughes TR, Rep M. Transcription Factors Encoded on Core and Accessory Chromosomes of Fusarium oxysporum Induce Expression of Effector Genes. Plos Genetics. 12: e1006401. PMID 27855160 DOI: 10.1371/journal.pgen.1006401  0.01
2016 Schmitges FW, Radovani E, Najafabadi HS, Barazandeh M, Campitelli LF, Yin Y, Jolma A, Zhong G, Guo H, Kanagalingam T, Dai WF, Taipale J, Emili A, Greenblatt JF, Hughes TR. Multiparameter functional diversity of human C2H2 zinc finger proteins. Genome Research. PMID 27852650 DOI: 10.1101/gr.209643.116  0.01
2016 Sundaram AY, Hughes T, Biondi S, Bolduc N, Bowman SK, Camilli A, Chew YC, Couture C, Farmer A, Jerome JP, Lazinski DW, McUsic A, Peng X, Shazand K, Xu F, et al. A comparative study of ChIP-seq sequencing library preparation methods. Bmc Genomics. 17: 816. PMID 27769162 DOI: 10.1186/s12864-016-3135-y  0.01
2016 Eadie LN, Hughes TP, White DL. ABCB1 Overexpression Is a Key Initiator of Resistance to Tyrosine Kinase Inhibitors in CML Cell Lines. Plos One. 11: e0161470. PMID 27536777 DOI: 10.1371/journal.pone.0161470  0.01
2016 Lambert SA, Albu M, Hughes TR, Najafabadi HS. Motif comparison based on similarity of binding affinity profiles. Bioinformatics (Oxford, England). PMID 27466627 DOI: 10.1093/bioinformatics/btw489  0.01
2016 Hughes TM, Worrall BB. Acute interatrial block is a distinct risk factor for ischemic stroke. Neurology. PMID 27343065 DOI: 10.1212/WNL.0000000000002905  0.01
2016 Towner LD, Wheat RA, Hughes TR, Morgan BP. Complement membrane attack and tumourigenesis: a systems biology approach. The Journal of Biological Chemistry. PMID 27226542 DOI: 10.1074/jbc.M115.708446  0.01
2016 Granados-Durán P, López-Ávalos MD, Hughes TR, Johnson K, Morgan BP, Tamburini PP, Fernández-Llebrez P, Grondona JM. Complement system activation contributes to the ependymal damage induced by microbial neuraminidase. Journal of Neuroinflammation. 13: 115. PMID 27209022 DOI: 10.1186/s12974-016-0576-9  0.01
2016 Selvarajah D, Hughes T, Reeves J, Boland E, Marques J, Gandhi R, Griffiths PD, Tesfaye S, Wilkinson ID. A preliminary study of brain macrovascular reactivity in impaired glucose tolerance and type-2 diabetes: Quantitative internal carotid artery blood flow using magnetic resonance phase contrast angiography. Diabetes & Vascular Disease Research. PMID 27190084 DOI: 10.1177/1479164116644404  0.01
2016 Barøy T, Pedurupillay CR, Bliksrud YT, Rasmussen M, Holmgren A, Vigeland MD, Hughes T, Brink M, Richard, Nedregaard B, Strømme P, Frengen E, Misceo D. A novel mutation in FBXL4 in a Norwegian child with encephalomyopathic mitochondrial DNA depletion syndrome 13. European Journal of Medical Genetics. PMID 27182039 DOI: 10.1016/j.ejmg.2016.05.005  0.01
2016 Mughal TI, Radich JP, Deininger MW, Apperley JF, Hughes TP, Harrison CJ, Gambacorti-Passerini C, Saglio G, Cortes J, Daley GQ. Chronic myeloid leukemia: reminiscences and dreams. Haematologica. 101: 541-558. PMID 27132280 DOI: 10.3324/haematol.2015.139337  0.01
2016 Lipton JH, Chuah C, Guerci-Bresler A, Rosti G, Simpson D, Assouline S, Etienne G, Nicolini FE, le Coutre P, Clark RE, Stenke L, Andorsky D, Oehler V, Lustgarten S, Rivera VM, ... ... Hughes T, et al. Ponatinib versus imatinib for newly diagnosed chronic myeloid leukaemia: an international, randomised, open-label, phase 3 trial. The Lancet. Oncology. PMID 27083332 DOI: 10.1016/S1470-2045(16)00080-2  0.01
2016 Hughes TP, Ross DM. Moving treatment-free remission into mainstream clinical practice in CML. Blood. PMID 27013442 DOI: 10.1182/blood-2016-01-694265  0.01
2016 Hsieh TH, Ishizuka H, Balents L, Hughes TL. Bulk Topological Proximity Effect. Physical Review Letters. 116: 086802. PMID 26967436 DOI: 10.1103/PhysRevLett.116.086802  0.01
2016 Tesli M, Wirgenes KV, Hughes T, Bettella F, Athanasiu L, Hoseth ES, Nerhus M, Lagerberg TV, Steen NE, Agartz I, Melle I, Dieset I, Djurovic S, Andreassen OA. VRK2 gene expression in schizophrenia, bipolar disorder and healthy controls. The British Journal of Psychiatry : the Journal of Mental Science. PMID 26941264 DOI: 10.1192/bjp.bp.115.161950  0.01
2016 Ilkhani H, Hughes T, Li J, Zhong CJ, Hepel M. Nanostructured SERS-electrochemical biosensors for testing of anticancer drug interactions with DNA. Biosensors & Bioelectronics. 80: 257-264. PMID 26851584 DOI: 10.1016/j.bios.2016.01.068  0.01
2016 Hochhaus A, Saglio G, Hughes TP, Larson RA, Kim DW, Issaragrisil S, le Coutre PD, Etienne G, Dorlhiac-Llacer PE, Clark RE, Flinn IW, Nakamae H, Donohue B, Deng W, Dalal D, et al. Long-term benefits and risks of frontline nilotinib vs imatinib for chronic myeloid leukemia in chronic phase: 5-year update of the randomized ENESTnd trial. Leukemia. PMID 26837842 DOI: 10.1038/leu.2016.5  0.01
2016 Latham S, Bartley PA, Budgen B, Ross DM, Hughes E, Branford S, White D, Hughes TP, Morley AA. BCR-ABL1 expression, RT-qPCR and treatment decisions in chronic myeloid leukaemia. Journal of Clinical Pathology. PMID 26837312 DOI: 10.1136/jclinpath-2015-203538  0.01
2016 Ye L, Lo BT, Qu J, Wilkinson I, Hughes T, Murray CA, Tang CC, Tsang SC. Probing atomic positions of adsorbed ammonia molecules in zeolite. Chemical Communications (Cambridge, England). PMID 26833032 DOI: 10.1039/c5cc10476a  0.01
2016 Parker WT, Yeung DT, Yeoman AL, Altamura HK, Jamison BA, Field CR, Hodgson JG, Lustgarten S, Rivera VM, Hughes TP, Branford S. The impact of multiple low-level BCR-ABL1 mutations on response to ponatinib. Blood. PMID 26773037 DOI: 10.1182/blood-2015-09-666214  0.01
2016 Mouillot D, Parravicini V, Bellwood DR, Leprieur F, Huang D, Cowman PF, Albouy C, Hughes TP, Thuiller W, Guilhaumon F. Global marine protected areas do not secure the evolutionary history of tropical corals and fishes. Nature Communications. 7: 10359. PMID 26756609 DOI: 10.1038/ncomms10359  0.01
2016 Zhang K, Dearing JA, Tong SL, Hughes TP. China's Degraded Environment Enters A New Normal. Trends in Ecology & Evolution. PMID 26753784 DOI: 10.1016/j.tree.2015.12.002  0.01
2016 Hughes T, Cardno A, West R, Marino-Francis F, Featherstone I, Rolling K, Locker A, McLintock K, House A. Unrecognised bipolar disorder among UK primary care patients prescribed antidepressants: an observational study. The British Journal of General Practice : the Journal of the Royal College of General Practitioners. PMID 26740604 DOI: 10.3399/bjgp16X683437  0.01
2016 Verma R, Foster RE, Horgan K, Mounsey K, Nixon H, Smalle N, Hughes TA, Carter CRD. Lymphocyte depletion and repopulation after chemotherapy for primary breast cancer Breast Cancer Research. DOI: 10.1186/s13058-015-0669-x  0.01
2016 Shapourian H, Hughes TL. Phase diagrams of disordered Weyl semimetals Physical Review B - Condensed Matter and Materials Physics. 93. DOI: 10.1103/PhysRevB.93.075108  0.01
2016 Luan B, Friedrich T, Zhai J, Streltsov VA, Lindsey BW, Kaslin J, De Jonge MD, Zhu J, Hughes TC, Hao X. A library of AuNPs modified by RAFT polymers of different charge and chain length: High throughput synthesis and synchrotron XFM imaging using a zebrafish larvae model Rsc Advances. 6: 23550-23563. DOI: 10.1039/c6ra02801b  0.01
2016 McAllister-Williams RH, Anderson IM, Finkelmeyer A, Gallagher P, Grunze HCR, Haddad PM, Hughes T, Lloyd AJ, Mamasoula C, McColl E, Pearce S, Siddiqi N, Sinha BNP, Steen N, Wainwright J, et al. Antidepressant augmentation with metyrapone for treatment-resistant depression (the ADD study): A double-blind, randomised, placebo-controlled trial The Lancet Psychiatry. 3: 117-127. DOI: 10.1016/S2215-0366(15)00436-8  0.01
2016 Rowland D, Hughes TJ, May EF. Extending the GERG-2008 equation of state: Improved departure function and interaction parameters for (methane + butane) Journal of Chemical Thermodynamics. 97: 206-213. DOI: 10.1016/j.jct.2016.01.005  0.01
2016 Sexton ZF, Hughes TJ, Wise KA. Analyzing isolate variability of Macrophomina phaseolina from a regional perspective Crop Protection. 81: 9-13. DOI: 10.1016/j.cropro.2015.11.012  0.01
2016 Evgeny B, Hughes T, Eskin D. Effect of surface roughness on corrosion behaviour of low carbon steel in inhibited 4 M hydrochloric acid under laminar and turbulent flow conditions Corrosion Science. 103: 196-205. DOI: 10.1016/j.corsci.2015.11.019  0.01
2016 Wei X, Zhang YJ, Hughes TJR, Scott MA. Extended Truncated Hierarchical Catmull-Clark Subdivision Computer Methods in Applied Mechanics and Engineering. 299: 316-336. DOI: 10.1016/j.cma.2015.10.024  0.01
2016 Oberai AA, Hughes TJR. A palette of fine-scale eddy viscosity and residual-based models for variational multiscale formulations of turbulence Computational Mechanics. 1-7. DOI: 10.1007/s00466-015-1242-2  0.01
2016 Hughes T. The benefits of dry-batch optimisation in a float glass plant Glass International. 38: 45-47.  0.01
2015 Kogar A, Vig S, Thaler A, Wong MH, Xiao Y, Reig-I-Plessis D, Cho GY, Valla T, Pan Z, Schneeloch J, Zhong R, Gu GD, Hughes TL, MacDougall GJ, Chiang TC, et al. Surface Collective Modes in the Topological Insulators Bi_{2}Se_{3} and Bi_{0.5}Sb_{1.5}Te_{3-x}Se_{x}. Physical Review Letters. 115: 257402. PMID 26722943 DOI: 10.1103/PhysRevLett.115.257402  0.01
2015 Bloom AC, Collins FL, Van't Hof RJ, Ryan ES, Jones E, Hughes TR, Paul Morgan B, Erlandsson M, Bokarewa M, Aeschlimann D, Evans BA, Williams AS. Deletion of the membrane complement inhibitor CD59a drives age and gender-dependent alterations to bone phenotype in mice. Bone. PMID 26721735 DOI: 10.1016/j.bone.2015.12.014  0.01
2015 le Coutre PD, Hughes TP, Mahon FX, Kim DW, Steegmann JL, Shah NP, Gooden K, Wallis N, Cortes JE. Low incidence of peripheral arterial disease in patients receiving dasatinib in clinical trials. Leukemia. PMID 26686247 DOI: 10.1038/leu.2015.352  0.01
2015 Hughes TM, Craft S. The Role of Insulin in the Vascular Contributions to Age-Related Dementia. Biochimica Et Biophysica Acta. PMID 26657615 DOI: 10.1016/j.bbadis.2015.11.013  0.01
2015 Tewson PH, Martinka S, Shaner NC, Hughes TE, Quinn AM. New DAG and cAMP Sensors Optimized for Live-Cell Assays in Automated Laboratories. Journal of Biomolecular Screening. PMID 26657040 DOI: 10.1177/1087057115618608  0.01
2015 Hughes T, Watts CR. The Effects of Two Resistive Exercises on Electrophysiological Measures of Submandibular Muscle Activity. Archives of Physical Medicine and Rehabilitation. PMID 26655623 DOI: 10.1016/j.apmr.2015.11.004  0.01
2015 Deininger MW, Hodgson JG, Shah NP, Cortes JE, Kim DW, Nicolini FE, Talpaz M, Baccarani M, Müller MC, Li J, Parker WT, Lustgarten S, Clackson T, Haluska FG, Guilhot F, ... Hughes TP, et al. Compound mutations in BCR-ABL1 are not major drivers of primary or secondary resistance to ponatinib in CP-CML patients. Blood. PMID 26603839 DOI: 10.1182/blood-2015-08-660977  0.01
2015 Sung U, Sepehri-Rad M, Piao HH, Jin L, Hughes T, Cohen LB, Baker BJ. Developing Fast Fluorescent Protein Voltage Sensors by Optimizing FRET Interactions. Plos One. 10: e0141585. PMID 26587834 DOI: 10.1371/journal.pone.0141585  0.01
2015 Traverso G, Ciccarelli G, Schwartz S, Hughes T, Boettcher T, Barman R, Langer R, Swiston A. Physiologic Status Monitoring via the Gastrointestinal Tract. Plos One. 10: e0141666. PMID 26580216 DOI: 10.1371/journal.pone.0141666  0.01
2015 Triantafilou M, Hughes TR, Morgan BP, Triantafilou K. Complementing the inflammasome. Immunology. PMID 26572245 DOI: 10.1111/imm.12556  0.01
2015 Hughes TM, Sink KM. Hypertension and Its Role in Cognitive Function: Current Evidence and Challenges for the Future. American Journal of Hypertension. PMID 26563965 DOI: 10.1093/ajh/hpv180  0.01
2015 Hughes TB, Varma VR, Pettigrew C, Albert MS. African Americans and Clinical Research: Evidence Concerning Barriers and Facilitators to Participation and Recruitment Recommendations. The Gerontologist. PMID 26553736 DOI: 10.1093/geront/gnv118  0.01
2015 Sachdev PS, Lipnicki DM, Kochan NA, Crawford JD, Thalamuthu A, Andrews G, Brayne C, Matthews FE, Stephan BC, Lipton RB, Katz MJ, Ritchie K, Carrière I, Ancelin ML, Lam LC, ... ... Hughes T, et al. The Prevalence of Mild Cognitive Impairment in Diverse Geographical and Ethnocultural Regions: The COSMIC Collaboration. Plos One. 10: e0142388. PMID 26539987 DOI: 10.1371/journal.pone.0142388  0.01
2015 Covshoff S, Szecowka M, Hughes TE, Smith-Unna R, Kelly S, Bailey KJ, Sage TL, Pachebat JA, Leegood RC, Hibberd JM. C4 photosynthesis in the rice paddy: insights from the noxious weed Echinochloa glabrescens. Plant Physiology. PMID 26527656 DOI: 10.1104/pp.15.00889  0.01
2015 Chagpar A, Babiera G, Aguirre J, Caropreso P, Hughes T. Variation in metastatic workup for patients with invasive breast cancer. American Journal of Surgery. PMID 26518161 DOI: 10.1016/j.amjsurg.2015.06.032  0.01
2015 Yeung DT, Tang C, Vidovic L, White DL, Branford S, Hughes TP, Yong AS. KIR2DL5B genotype predicts outcomes in CML patients treated with response directed sequential imatinib / nilotinib strategy. Blood. PMID 26500342 DOI: 10.1182/blood-2015-07-655589  0.01
2015 Snitz BE, Small BJ, Wang T, Chang CC, Hughes TF, Ganguli M. Do Subjective Memory Complaints Lead or Follow Objective Cognitive Change? A Five-Year Population Study of Temporal Influence. Journal of the International Neuropsychological Society : Jins. 21: 732-42. PMID 26477680 DOI: 10.1017/S1355617715000922  0.01
2015 McNair R, Pennay A, Hughes T, Brown R, Leonard W, Lubman DI. A model for lesbian, bisexual and queer-related influences on alcohol consumption and implications for policy and practice. Culture, Health & Sexuality. 1-17. PMID 26466746 DOI: 10.1080/13691058.2015.1089602  0.01
2015 Bulleid LS, Hughes T, Bhatti I, Leach PA. Low-pressure headaches following foramen magnum decompression secondary to absorption of cerebrospinal fluid into the venous system of the diploic space. Child's Nervous System : Chns : Official Journal of the International Society For Pediatric Neurosurgery. PMID 26445976 DOI: 10.1007/s00381-015-2928-7  0.01
2015 Jerome SV, Hughes TF, Friesner RA. Successful application of the DBLOC method to the hydroxylation of camphor by cytochrome p450. Protein Science : a Publication of the Protein Society. PMID 26441133 DOI: 10.1002/pro.2819  0.01
2015 Smith L, Baxter EW, Chambers PA, Green CA, Hanby AM, Hughes TA, Nash CE, Millican-Slater RA, Stead LF, Verghese ET, Speirs V. Down-Regulation of miR-92 in Breast Epithelial Cells and in Normal but Not Tumour Fibroblasts Contributes to Breast Carcinogenesis. Plos One. 10: e0139698. PMID 26437339 DOI: 10.1371/journal.pone.0139698  0.01
2015 Hughes T, Klairmont M, Sharfman WH, Kaufman HL. Interleukin-2, Ipilimumab, and Anti-PD-1: Clinical Management and the Evolving Role of Immunotherapy for the Treatment of Patients With Metastatic Melanoma. Cancer Biology & Therapy. 0. PMID 26418961 DOI: 10.1080/15384047.2015.1095401  0.01
2015 Hughes HE, Morbey R, Hughes TC, Locker TE, Pebody R, Green HK, Ellis J, Smith GE, Elliot AJ. Emergency department syndromic surveillance providing early warning of seasonal respiratory activity in England. Epidemiology and Infection. 1-13. PMID 26415918 DOI: 10.1017/S0950268815002125  0.01
2015 Chutake YK, Costello WN, Lam CC, Parikh AC, Hughes TT, Michalopulos MG, Pook MA, Bidichandani SI. FXN Promoter Silencing in the Humanized Mouse Model of Friedreich Ataxia. Plos One. 10: e0138437. PMID 26393353 DOI: 10.1371/journal.pone.0138437  0.01
2015 Kim B, Stephen SL, Hanby AM, Horgan K, Perry SL, Richardson J, Roundhill EA, Valleley EM, Verghese ET, Williams BJ, Thorne JL, Hughes TA. Chemotherapy induces Notch1-dependent MRP1 up-regulation, inhibition of which sensitizes breast cancer cells to chemotherapy. Bmc Cancer. 15: 634. PMID 26362310 DOI: 10.1186/s12885-015-1625-y  0.01
2015 Sharples AP, Polydorou I, Hughes DC, Owens DJ, Hughes TM, Stewart CE. Skeletal muscle cells possess a 'memory' of acute early life TNF-α exposure: role of epigenetic adaptation. Biogerontology. PMID 26349924 DOI: 10.1007/s10522-015-9604-x  0.01
2015 Taylor JJ, Larrew T, Omole A, Roberts M, Kornegay A, Kornegay K, Yamada L, Revuelta GJ, Sohn M, Hughes T, Edwards JC. The feasibility of establishing a free clinic for uninsured patients with neurologic disorders. Neurology. Clinical Practice. 5: 302-308. PMID 26336631 DOI: 10.1212/CPJ.0000000000000154  0.01
2015 Hughes TL, Wilsnack SC, Kristjanson AF. Substance use and related problems among U.S. women who identify as mostly heterosexual. Bmc Public Health. 15: 803. PMID 26289792 DOI: 10.1186/s12889-015-2143-1  0.01
2015 Kojetin DJ, Matta-Camacho E, Hughes TS, Srinivasan S, Nwachukwu JC, Cavett V, Nowak J, Chalmers MJ, Marciano DP, Kamenecka TM, Shulman AI, Rance M, Griffin PR, Bruning JB, Nettles KW. Structural mechanism for signal transduction in RXR nuclear receptor heterodimers. Nature Communications. 6: 8013. PMID 26289479 DOI: 10.1038/ncomms9013  0.01
2015 Drobizhev M, Callis PR, Nifosì R, Wicks G, Stoltzfus C, Barnett L, Hughes TE, Sullivan P, Rebane A. Long- and Short-Range Electrostatic Fields in GFP Mutants: Implications for Spectral Tuning. Scientific Reports. 5: 13223. PMID 26286372 DOI: 10.1038/srep13223  0.01
2015 Chung J, Smith AL, Hughes SC, Niizawa G, Abdel-Hamid HZ, Naylor EW, Hughes T, Clemens PR. 20-year Follow-up of newborn screening for patients with muscular dystrophy. Muscle & Nerve. PMID 26260293 DOI: 10.1002/mus.24880  0.01
2015 Bhat V, Olmer M, Joshi S, Durden DL, Cramer TJ, Barnes R, Ball ST, Hughes TH, Silva M, Luck JV, Moore RE, Mosnier LO, von Drygalski A. Vascular Remodeling Underlies Re-bleeding In Hemophilic Arthropathy. American Journal of Hematology. PMID 26257191 DOI: 10.1002/ajh.24133  0.01
2015 Hughes TS, Wilson HD, de Vera IM, Kojetin DJ. Deconvolution of Complex 1D NMR Spectra Using Objective Model Selection. Plos One. 10: e0134474. PMID 26241959 DOI: 10.1371/journal.pone.0134474  0.01
2015 Storace D, Rad MS, Han Z, Jin L, Cohen LB, Hughes T, Baker BJ, Sung U. Genetically Encoded Protein Sensors of Membrane Potential. Advances in Experimental Medicine and Biology. 859: 493-509. PMID 26238066 DOI: 10.1007/978-3-319-17641-3_20  0.01
2015 Hughes TJ, Cardamone S, Popelier PL. Realistic sampling of amino acid geometries for a multipolar polarizable force field. Journal of Computational Chemistry. 36: 1844-57. PMID 26235784 DOI: 10.1002/jcc.24006  0.01
2015 Mihailidis S, Bockmann M, McConnell E, Hughes T, van Beijsterveldt TC, Boomsma DI, McMaster M, Townsend G. The Influence of Chorion Type on Health Measures at Birth and Dental Development in Australian and Dutch Twins: A Comparative Study. Twin Research and Human Genetics : the Official Journal of the International Society For Twin Studies. 18: 368-74. PMID 26227835 DOI: 10.1017/thg.2015.43  0.01
2015 Barøy T, Koster J, Strømme P, Ebberink MS, Misceo D, Ferdinandusse S, Holmgren A, Hughes T, Merckoll E, Westvik J, Woldseth B, Walter J, Wood N, Tvedt B, Stadskleiv K, et al. A novel type of rhizomelic chondrodysplasia punctata, RCDP5, is caused by loss of the PEX5 long isoform. Human Molecular Genetics. 24: 5845-54. PMID 26220973 DOI: 10.1093/hmg/ddv305  0.01
2015 Sarkisyan KS, Goryashchenko AS, Lidsky PV, Gorbachev DA, Bozhanova NG, Gorokhovatsky AY, Pereverzeva AR, Ryumina AP, Zherdeva VV, Savitsky AP, Solntsev KM, Bommarius AS, Sharonov GV, Lindquist JR, Drobizhev M, Hughes TE, et al. Green fluorescent protein with anionic tryptophan-based chromophore and long fluorescence lifetime. Biophysical Journal. 109: 380-9. PMID 26200874 DOI: 10.1016/j.bpj.2015.06.018  0.01
2015 Jayme SI, Field HE, de Jong C, Olival KJ, Marsh G, Tagtag AM, Hughes T, Bucad AC, Barr J, Azul RR, Retes LM, Foord A, Yu M, Cruz MS, Santos IJ, et al. Molecular evidence of Ebola Reston virus infection in Philippine bats. Virology Journal. 12: 107. PMID 26184657 DOI: 10.1186/s12985-015-0331-3  0.01
2015 Odeh R, Mihailidis S, Townsend G, Lähdesmäki R, Hughes T, Brook A. Prevalence of infraocclusion of primary molars determined using a new 2D image analysis methodology. Australian Dental Journal. PMID 26174549 DOI: 10.1111/adj.12349  0.01
2015 Peng S, Hartley PG, Hughes TC, Guo Q. Enhancing thermal stability and mechanical properties of lyotropic liquid crystals through incorporation of a polymerizable surfactant. Soft Matter. 11: 6318-26. PMID 26166631 DOI: 10.1039/c5sm01646k  0.01
2015 Odeh R, Townsend G, Mihailidis S, Lähdesmäki R, Hughes T, Brook A. Infraocclusion: Dental development and associated dental variations in singletons and twins. Archives of Oral Biology. 60: 1394-402. PMID 26150229 DOI: 10.1016/j.archoralbio.2015.06.010  0.01
2015 Stoltzfus CR, Barnett LM, Drobizhev M, Wicks G, Mikhaylov A, Hughes TE, Rebane A. Two-photon directed evolution of green fluorescent proteins. Scientific Reports. 5: 11968. PMID 26145791 DOI: 10.1038/srep11968  0.01
2015 White DL, Hughes TP. Living with CML: is death no longer the end (point)? Blood. 126: 2-4. PMID 26138535 DOI: 10.1182/blood-2015-05-644732  0.01
2015 Ong J, Yeung D, Filshie R, Hughes TP, Nandurkar H. Imatinib-induced gastric antral vascular ectasia in three patients with chronic myeloid leukaemia. International Journal of Hematology. 102: 639-42. PMID 26134364 DOI: 10.1007/s12185-015-1824-y  0.01
2015 Cook A, Frankel G, Davenport A, Hughes T, Gibbon S, Williams D, Bluhm H, Maurice V, Lyth S, Marcus P, Shoesmith D, Wren C, Wharton J, Hunt G, Lyon S, et al. Corrosion control: general discussion. Faraday Discussions. PMID 26134287 DOI: 10.1039/c5fd90047f  0.01
2015 Frankel G, Thornton G, Street S, Rayment T, Williams D, Cook A, Davenport A, Gibbon S, Engelberg D, Örnek C, Mol A, Marcus P, Shoesmith D, Wren C, Yliniemi K, ... ... Hughes T, et al. Localised corrosion: general discussion. Faraday Discussions. PMID 26132340 DOI: 10.1039/c5fd90046h  0.01
2015 Watkins DB, Hughes TP, White DL. OCT1 and imatinib transport in CML: is it clinically relevant? Leukemia. PMID 26122430 DOI: 10.1038/leu.2015.170  0.01
2015 Hughes TP, Saglio G, Quintás-Cardama A, Mauro MJ, Kim DW, Lipton JH, Bradley-Garelik MB, Ukropec J, Hochhaus A. BCR-ABL1 mutation development during first-line treatment with dasatinib or imatinib for chronic myeloid leukemia in chronic phase. Leukemia. PMID 26118315 DOI: 10.1038/leu.2015.168  0.01
2015 Wadsworth MH, Hughes TK, Shalek AK. Marrying microfluidics and microwells for parallel, high-throughput single-cell genomics. Genome Biology. 16: 129. PMID 26087845 DOI: 10.1186/s13059-015-0695-0  0.01
2015 Lee MH, Rostal MK, Hughes T, Sitam F, Lee CY, Japning J, Harden ME, Griffiths A, Basir M, Wolfe ND, Epstein JH, Daszak P. Macacine Herpesvirus 1 in Long-Tailed Macaques, Malaysia, 2009-2011. Emerging Infectious Diseases. 21: 1107-13. PMID 26080081 DOI: 10.3201/eid2107.140162  0.01
2015 Marciano DP, Kuruvilla DS, Boregowda SV, Asteian A, Hughes TS, Garcia-Ordonez R, Corzo CA, Khan TM, Novick SJ, Park H, Kojetin DJ, Phinney DG, Bruning JB, Kamenecka TM, Griffin PR. Pharmacological repression of PPARγ promotes osteogenesis. Nature Communications. 6: 7443. PMID 26068133 DOI: 10.1038/ncomms8443  0.01
2015 Brown R, McNair R, Szalacha L, Livingston PM, Hughes T. Cancer Risk Factors, Diagnosis and Sexual Identity in the Australian Longitudinal Study of Women's Health. Women's Health Issues : Official Publication of the Jacobs Institute of Women's Health. PMID 26044972 DOI: 10.1016/j.whi.2015.04.001  0.01
2015 McCully ML, Collins PJ, Hughes TR, Thomas CP, Billen J, O'Donnell VB, Moser B. Skin Metabolites Define a New Paradigm in the Localization of Skin Tropic Memory T Cells. Journal of Immunology (Baltimore, Md. : 1950). 195: 96-104. PMID 26002980 DOI: 10.4049/jimmunol.1402961  0.01
2015 Kohlhapp FJ, Broucek JR, Hughes T, Huelsmann EJ, Lusciks J, Zayas JP, Dolubizno H, Fleetwood VA, Grin A, Hill GE, Poshepny JL, Nabatiyan A, Ruby CE, Snook JD, Rudra JS, et al. NK cells and CD8+ T cells cooperate to improve therapeutic responses in melanoma treated with interleukin-2 (IL-2) and CTLA-4 blockade. Journal For Immunotherapy of Cancer. 3: 18. PMID 25992289 DOI: 10.1186/s40425-015-0063-3  0.01
2015 Calderon RM, Diaz S, Szeto A, Llinas JA, Hughes TA, Mendez AJ, Goldberg RB. Elevated Lipoprotein Lipase Activity Does Not Account for the Association Between Adiponectin and HDL in Type 1 Diabetes. The Journal of Clinical Endocrinology and Metabolism. 100: 2581-8. PMID 25942477 DOI: 10.1210/jc.2015-1357  0.01
2015 Jaffe DE, Yoo D, Blevins J, Gasbarro G, Hughes T, Paryavi E, Nguyen T, Fourney WL, Pellegrini VD. Does Blast Medium Affect Heterotopic Ossification in a Blast-amputation Model? Clinical Orthopaedics and Related Research. 473: 2680-7. PMID 25917424 DOI: 10.1007/s11999-015-4320-z  0.01
2015 Talley AE, Aranda F, Hughes TL, Everett B, Johnson TP. Longitudinal Associations among Discordant Sexual Orientation Dimensions and Hazardous Drinking in a Cohort of Sexual Minority Women. Journal of Health and Social Behavior. 56: 225-45. PMID 25911224 DOI: 10.1177/0022146515582099  0.01
2015 Hayes J, Thygesen H, Droop A, Hughes TA, Westhead D, Lawler SE, Wurdak H, Short SC. Prognostic microRNAs in high-grade glioma reveal a link to oligodendrocyte precursor differentiation. Oncoscience. 2: 252-62. PMID 25897422 DOI: 10.18632/oncoscience.112  0.01
2015 Rasmussen HB, Bjerre D, Linnet K, Jürgens G, Dalhoff K, Stefansson H, Hankemeier T, Kaddurah-Daouk R, Taboureau O, Brunak S, Houmann T, Jeppesen P, Pagsberg AK, Plessen K, Dyrborg J, ... ... Hughes T, et al. Individualization of treatments with drugs metabolized by CES1: combining genetics and metabolomics. Pharmacogenomics. 16: 649-65. PMID 25896426 DOI: 10.2217/pgs.15.7  0.01
2015 Hughes TM, Craft S, Lopez OL. Review of 'the potential role of arterial stiffness in the pathogenesis of Alzheimer's disease'. Neurodegenerative Disease Management. 5: 121-35. PMID 25894876 DOI: 10.2217/nmt.14.53  0.01
2015 Hossain SS, Zhang Y, Fu X, Brunner G, Singh J, Hughes TJ, Shah D, Decuzzi P. Magnetic resonance imaging-based computational modelling of blood flow and nanomedicine deposition in patients with peripheral arterial disease. Journal of the Royal Society, Interface / the Royal Society. 12. PMID 25878124 DOI: 10.1098/rsif.2015.0001  0.01
2015 Guan Y, Meurer M, Raghavan S, Rebane A, Lindquist JR, Santos S, Kats I, Davidson MW, Mazitschek R, Hughes TE, Drobizhev M, Knop M, Shah JV. Live-cell multiphoton fluorescence correlation spectroscopy with an improved large Stokes shift fluorescent protein. Molecular Biology of the Cell. 26: 2054-66. PMID 25877871 DOI: 10.1091/mbc.E14-10-1473  0.01
2015 Lally K, Cofer J, Von Allman D, Richmond B, Hughes T, Huang EY. Discussion Journal of the American College of Surgeons. 220: 746-748. PMID 25797761 DOI: 10.1016/j.jamcollsurg.2015.01.047  0.01
2015 Scheffer M, Barrett S, Carpenter SR, Folke C, Green AJ, Holmgren M, Hughes TP, Kosten S, van de Leemput IA, Nepstad DC, van Nes EH, Peeters ET, Walker B. Climate and conservation. Creating a safe operating space for iconic ecosystems. Science (New York, N.Y.). 347: 1317-9. PMID 25792318 DOI: 10.1126/science.aaa3769  0.01
2015 Aiken MJ, Hughes TK, Abercromby RH, Holmes MA, Anderson AA. Prospective, Randomized Comparison of the Effect of Two Antimicrobial Regimes on Surgical Site Infection Rate in Dogs Undergoing Orthopedic Implant Surgery. Veterinary Surgery : Vs. 44: 661-7. PMID 25780942 DOI: 10.1111/vsu.12327  0.01
2015 Hughes TL. Developing a Research Career Focusing on a Stigmatized and Marginalized Population: Sexual Minority Women's Drinking. Substance Abuse. 36: 144-8. PMID 25775206 DOI: 10.1080/08897077.2015.1007202  0.01
2015 Deng Y, Kerdiles Y, Chu J, Yuan S, Wang Y, Chen X, Mao H, Zhang L, Zhang J, Hughes T, Deng Y, Zhang Q, Wang F, Zou X, Liu CG, et al. Transcription factor Foxo1 is a negative regulator of natural killer cell maturation and function. Immunity. 42: 457-70. PMID 25769609 DOI: 10.1016/j.immuni.2015.02.006  0.01
2015 Hughes TB, Miller GP, Swamidass SJ. Site of reactivity models predict molecular reactivity of diverse chemicals with glutathione. Chemical Research in Toxicology. 28: 797-809. PMID 25742281 DOI: 10.1021/acs.chemrestox.5b00017  0.01
2015 Kim DD, Krishnarajah J, Lillioja S, de Looze F, Marjason J, Proietto J, Shakib S, Stuckey BG, Vath JE, Hughes TE. Efficacy and safety of beloranib for weight loss in obese adults: a randomized controlled trial. Diabetes, Obesity & Metabolism. 17: 566-72. PMID 25732625 DOI: 10.1111/dom.12457  0.01
2015 Zaretzki JM, Browning MR, Hughes TB, Swamidass SJ. Extending P450 site-of-metabolism models with region-resolution data. Bioinformatics (Oxford, England). 31: 1966-73. PMID 25697821 DOI: 10.1093/bioinformatics/btv100  0.01
2015 Tiernan JP, Ingram N, Marston G, Perry SL, Rushworth JV, Coletta PL, Millner PA, Jayne DG, Hughes TA. CEA-targeted nanoparticles allow specific in vivo fluorescent imaging of colorectal cancer models. Nanomedicine (London, England). 10: 1223-31. PMID 25694062 DOI: 10.2217/nnm.14.202  0.01
2015 Hughes TF, Becker JT, Lee CW, Chang CC, Ganguli M. Independent and combined effects of cognitive and physical activity on incident MCI. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25684687 DOI: 10.1016/j.jalz.2014.11.007  0.01
2015 Lu L, Saunders VA, Leclercq TM, Hughes TP, White DL. Ponatinib is not transported by ABCB1, ABCG2 or OCT-1 in CML cells. Leukemia. PMID 25676419 DOI: 10.1038/leu.2015.35  0.01
2015 Liu Y, Muir BW, Waddington LJ, Hinton TM, Moffat BA, Hao X, Qiu J, Hughes TC. Colloidally stabilized magnetic carbon nanotubes providing MRI contrast in mouse liver tumors. Biomacromolecules. 16: 790-7. PMID 25649901 DOI: 10.1021/bm501706x  0.01
2015 Ding Y, Li J, Enterina JR, Shen Y, Zhang I, Tewson PH, Mo GC, Zhang J, Quinn AM, Hughes TE, Maysinger D, Alford SC, Zhang Y, Campbell RE. Ratiometric biosensors based on dimerization-dependent fluorescent protein exchange. Nature Methods. 12: 195-8. PMID 25622108 DOI: 10.1038/nmeth.3261  0.01
2015 Koues OI, Kowalewski RA, Chang LW, Pyfrom SC, Schmidt JA, Luo H, Sandoval LE, Hughes TB, Bednarski JJ, Cashen AF, Payton JE, Oltz EM. Enhancer sequence variants and transcription-factor deregulation synergize to construct pathogenic regulatory circuits in B-cell lymphoma. Immunity. 42: 186-98. PMID 25607463 DOI: 10.1016/j.immuni.2014.12.021  0.01
2015 Hughes T, Klairmont M, Broucek J, Iodice G, Basu S, Kaufman HL. The prognostic significance of stable disease following high-dose interleukin-2 (IL-2) treatment in patients with metastatic melanoma and renal cell carcinoma. Cancer Immunology, Immunotherapy : Cii. 64: 459-65. PMID 25603775 DOI: 10.1007/s00262-014-1652-6  0.01
2015 Liao GP, Harting MT, Hetz RA, Walker PA, Shah SK, Corkins CJ, Hughes TG, Jimenez F, Kosmach SC, Day MC, Tsao K, Lee DA, Worth LL, Baumgartner JE, Cox CS. Autologous bone marrow mononuclear cells reduce therapeutic intensity for severe traumatic brain injury in children. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 16: 245-55. PMID 25581630 DOI: 10.1097/PCC.0000000000000324  0.01
2015 Qie F, Astolfo A, Wickramaratna M, Behe M, Evans MD, Hughes TC, Hao X, Tan T. Self-assembled gold coating enhances X-ray imaging of alginate microcapsules. Nanoscale. 7: 2480-8. PMID 25567482 DOI: 10.1039/c4nr06692h  0.01
2015 Farooqui MZ, Valdez J, Martyr S, Aue G, Saba N, Niemann CU, Herman SE, Tian X, Marti G, Soto S, Hughes TE, Jones J, Lipsky A, Pittaluga S, Stetler-Stevenson M, et al. Ibrutinib for previously untreated and relapsed or refractory chronic lymphocytic leukaemia with TP53 aberrations: a phase 2, single-arm trial. The Lancet. Oncology. 16: 169-76. PMID 25555420 DOI: 10.1016/S1470-2045(14)71182-9  0.01
2015 Bartley PA, Latham S, Budgen B, Ross DM, Hughes E, Branford S, White D, Hughes TP, Morley AA. A DNA real-time quantitative PCR method suitable for routine monitoring of low levels of minimal residual disease in chronic myeloid leukemia. The Journal of Molecular Diagnostics : Jmd. 17: 185-92. PMID 25554588 DOI: 10.1016/j.jmoldx.2014.10.002  0.01
2015 Hughes T, Harrer JU. Treating arterial disease to prevent brain injury: Break out the bubbly or back to the bench? Neurology. 84: 440-1. PMID 25552574 DOI: 10.1212/WNL.0000000000001218  0.01
2015 Kamensky D, Hsu MC, Schillinger D, Evans JA, Aggarwal A, Bazilevs Y, Sacks MS, Hughes TJ. An immersogeometric variational framework for fluid-structure interaction: application to bioprosthetic heart valves. Computer Methods in Applied Mechanics and Engineering. 284: 1005-1053. PMID 25541566 DOI: 10.1016/j.cma.2014.10.040  0.01
2015 Yeung DT, Osborn MP, White DL, Branford S, Braley J, Herschtal A, Kornhauser M, Issa S, Hiwase DK, Hertzberg M, Schwarer AP, Filshie R, Arthur CK, Kwan YL, Trotman J, ... Hughes TP, et al. TIDEL-II: first-line use of imatinib in CML with early switch to nilotinib for failure to achieve time-dependent molecular targets. Blood. 125: 915-23. PMID 25519749 DOI: 10.1182/blood-2014-07-590315  0.01
2015 Hayes J, Thygesen H, Tumilson C, Droop A, Boissinot M, Hughes TA, Westhead D, Alder JE, Shaw L, Short SC, Lawler SE. Prediction of clinical outcome in glioblastoma using a biologically relevant nine-microRNA signature. Molecular Oncology. 9: 704-14. PMID 25499534 DOI: 10.1016/j.molonc.2014.11.004  0.01
2015 Ganguli M, Lee CW, Snitz BE, Hughes TF, McDade E, Chang CC. Rates and risk factors for progression to incident dementia vary by age in a population cohort. Neurology. 84: 72-80. PMID 25471390 DOI: 10.1212/WNL.0000000000001113  0.01
2015 Warren SH, Claxton LD, Diliberto J, Hughes TJ, Swank A, Kusnierz DH, Marshall V, DeMarini DM. Survey of the mutagenicity of surface water, sediments, and drinking water from the Penobscot Indian Nation. Chemosphere. 120: 690-6. PMID 25462314 DOI: 10.1016/j.chemosphere.2014.10.002  0.01
2015 Fowler JR, Hughes TB. Scaphoid fractures. Clinics in Sports Medicine. 34: 37-50. PMID 25455395 DOI: 10.1016/j.csm.2014.09.011  0.01
2015 Matlock MK, Hughes TB, Swamidass SJ. XenoSite server: a web-available site of metabolism prediction tool. Bioinformatics (Oxford, England). 31: 1136-7. PMID 25411327 DOI: 10.1093/bioinformatics/btu761  0.01
2015 Yeung DT, Moulton DJ, Heatley SL, Nievergall E, Dang P, Braley J, Branford S, Moore S, Mullighan CG, Hughes TP, White DL. Relapse of BCR-ABL1-like ALL mediated by the ABL1 kinase domain mutation T315I following initial response to dasatinib treatment. Leukemia. 29: 230-2. PMID 25179732 DOI: 10.1038/leu.2014.256  0.01
2015 Lickliter JD, Taylor K, Szer J, Grigg A, Arthur C, Hughes TP, Durrant S, Filshie R, Irving I, Seldon M, Ellacott J, Boyd AW, D'Rozario J, Rooney K, Lynch K, et al. An imatinib-only window followed by imatinib and chemotherapy for Philadelphia chromosome-positive acute leukemia: long-term results of the CMLALL1 trial. Leukemia & Lymphoma. 56: 630-8. PMID 24844361 DOI: 10.3109/10428194.2014.925547  0.01
2015 Schafranek L, Nievergall E, Powell JA, Hiwase DK, Leclercq T, Hughes TP, White DL. Sustained inhibition of STAT5, but not JAK2, is essential for TKI-induced cell death in chronic myeloid leukemia. Leukemia. 29: 76-85. PMID 24813920 DOI: 10.1038/leu.2014.156  0.01
2015 Hequembourg AL, Parks KA, Collins RL, Hughes TL. Sexual assault risks among gay and bisexual men. Journal of Sex Research. 52: 282-95. PMID 24483778 DOI: 10.1080/00224499.2013.856836  0.01
2015 Hughes TJ, Kandathil SM, Popelier PL. Accurate prediction of polarised high order electrostatic interactions for hydrogen bonded complexes using the machine learning method kriging. Spectrochimica Acta. Part a, Molecular and Biomolecular Spectroscopy. 136: 32-41. PMID 24274986 DOI: 10.1016/j.saa.2013.10.059  0.01
2015 Zhao M, Cai C, Zhai J, Lin F, Li L, Shreve J, Thimmapuram J, Hughes TJ, Meyers BC, Ma J. Coordination of microRNAs, phasiRNAs, and NB-LRR genes in response to a plant pathogen: Insights from analyses of a set of soybean rps gene near-isogenic lines Plant Genome. 8. DOI: 10.3835/plantgenome2014.09.0044  0.01
2015 Tiernan JP, Ingram N, Marston G, Perry SL, Rushworth JV, Coletta PL, Millner PA, Jayne DG, Hughes TA. CEA-targeted nanoparticles allow specific in vivo fluorescent imaging of colorectal cancer models Nanomedicine. 10: 1223-1231. DOI: 10.2217/nnm.14.202  0.01
2015 Taylor JJ, Larrew T, Omole A, Roberts M, Kornegay A, Kornegay K, Yamada L, Revuelta GJ, Sohn M, Hughes T, Edwards JC. The feasibility of establishing a free clinic for uninsured patients with neurologic disorders Neurology: Clinical Practice. 5: 302-308. DOI: 10.1212/CPJ.0000000000000154  0.01
2015 Jayme SI, Field HE, De Jong C, Olival KJ, Marsh G, Tagtag AM, Hughes T, Bucad AC, Barr J, Azul RR, Retes LM, Foord A, Yu M, Cruz MS, Santos IJ, et al. Molecular evidence of Ebola Reston virus infection in Philippine bats Virology Journal. 12. DOI: 10.1186/s12985-015-0331-3  0.01
2015 Hughes TL, Wilsnack SC, Kristjanson AF. Substance use and related problems among U.S. women who identify as mostly heterosexual Bmc Public Health. 15. DOI: 10.1186/s12889-015-2143-1  0.01
2015 White DL, Hughes TP. Living with CML: Is death no longer the end (point)? Blood. 126: 2-4. DOI: 10.1182/blood-2015-05-644732  0.01
2015 Hughes T, Carlson D. Divided Government and Delay in the Legislative Process: Evidence From Important Bills, 1949-2010 American Politics Research. 43: 771-792. DOI: 10.1177/1532673X15574594  0.01
2015 Talley AE, Aranda F, Hughes TL, Everett B, Johnson TP. Longitudinal Associations among Discordant Sexual Orientation Dimensions and Hazardous Drinking in a Cohort of Sexual Minority Women Journal of Health and Social Behavior. 56: 225-245. DOI: 10.1177/0022146515582099  0.01
2015 Murdock SE, Hughes TF, Kwak HS, Goldberg A, Giesen DJ, Cao Y, Sanders J, Gavartin J, Dathar GKP, Halls MD. Discovery of new Anode SEI forming additives using an in silico evolutionary approach Ecs Transactions. 69: 67-74. DOI: 10.1149/06901.0067ecst  0.01
2015 Beirão Da Veiga L, Hughes TJR, Kiendl J, Lovadina C, Niiranen J, Reali A, Speleers H. A locking-free model for Reissner-Mindlin plates: Analysis and isogeometric implementation via NURBS and triangular NURPS Mathematical Models and Methods in Applied Sciences. 25: 1519-1551. DOI: 10.1142/S0218202515500402  0.01
2015 Bray E, Harding K, Hughes T. Thinking, fast and slow Practical Neurology. 15: 327. DOI: 10.1136/practneurol-2015-001218  0.01
2015 Hughes T. The man who mistook his wife for a hat Practical Neurology. 15: 155. DOI: 10.1136/practneurol-2015-001124  0.01
2015 Hughes TJ, Henstock TJ, Pilgrim JA, Dix JK, Gernon TM, Thompson CEL. Effect of Sediment Properties on the Thermal Performance of Submarine HV Cables Ieee Transactions On Power Delivery. 30: 2443-2450. DOI: 10.1109/TPWRD.2015.2398351  0.01
2015 Hughes T, Romero MC. A processural consent methodology with people diagnosed with dementia Quality in Ageing and Older Adults. 16: 222-234. DOI: 10.1108/QAOA-03-2015-0012  0.01
2015 Shapourian H, Hughes TL, Ryu S. Viscoelastic response of topological tight-binding models in two and three dimensions Physical Review B - Condensed Matter and Materials Physics. 92. DOI: 10.1103/PhysRevB.92.165131  0.01
2015 Tuegel TI, Hughes TL. Hall viscosity and momentum transport in lattice and continuum models of the integer quantum Hall effect in strong magnetic fields Physical Review B - Condensed Matter and Materials Physics. 92. DOI: 10.1103/PhysRevB.92.165127  0.01
2015 Ramamurthy ST, Hughes TL. Patterns of electromagnetic response in topological semimetals Physical Review B - Condensed Matter and Materials Physics. 92. DOI: 10.1103/PhysRevB.92.085105  0.01
2015 Cano J, Hughes TL, Mulligan M. Interactions along an entanglement cut in 2+1 D Abelian topological phases Physical Review B - Condensed Matter and Materials Physics. 92. DOI: 10.1103/PhysRevB.92.075104  0.01
2015 Mondragon-Shem I, Pal A, Hughes TL, Laumann CR. Many-body mobility edge due to symmetry-constrained dynamics and strong interactions Physical Review B - Condensed Matter and Materials Physics. 92. DOI: 10.1103/PhysRevB.92.064203  0.01
2015 Zhuang Y, Changlani HJ, Tubman NM, Hughes TL. Phase diagram of the Z3 parafermionic chain with chiral interactions Physical Review B - Condensed Matter and Materials Physics. 92. DOI: 10.1103/PhysRevB.92.035154  0.01
2015 Cho GY, Parrikar O, You Y, Leigh RG, Hughes TL. Condensation of lattice defects and melting transitions in quantum Hall phases Physical Review B - Condensed Matter and Materials Physics. 91. DOI: 10.1103/PhysRevB.91.035122  0.01
2015 Agius NK, di Serego Alighieri S, Viaene S, Baes M, Sansom AE, Bourne N, Bland-Hawthorn J, Brough S, Davis TA, De Looze I, Driver SP, Dunne L, Dye S, Eales SA, Hughes TM, et al. H-ATLAS/GAMA and HeViCS -dusty early-type galaxies in different environments Monthly Notices of the Royal Astronomical Society. 451: 3815-3835. DOI: 10.1093/mnras/stv1191  0.01
2015 De Geyter G, Baes M, De Looze I, Bendo GJ, Bourne N, Camps P, Cooray A, De Zotti G, Dunne L, Dye S, Eales SA, Fritz J, Furlanetto C, Gentile G, Hughes TM, et al. Dust energy balance study of two edge-on spiral galaxies in the Herschel-ATLAS survey Monthly Notices of the Royal Astronomical Society. 451: 1728-1739. DOI: 10.1093/mnras/stv1104  0.01
2015 Hughes TL. Developing a research career focusing on a stigmatized and marginalized population: Sexual minority women's drinking Substance Abuse. 36: 144-148. DOI: 10.1080/08897077.2015.1007202  0.01
2015 Chalcraft D, Hilton T, Hughes T. Customer, collaborator or co-creator? What is the role of the student in a changing higher education servicescape? Journal of Marketing For Higher Education. 25: 1-4. DOI: 10.1080/08841241.2015.1044790  0.01
2015 Flatt JD, Hughes TF, Documét PI, Lingler JH, Trauth JM, Albert SM. A Qualitative Study on the Types and Purposes of Social Activities in Late Life Activities, Adaptation and Aging. 39: 109-132. DOI: 10.1080/01924788.2015.1024485  0.01
2015 Hughes TW, Lee K. The role of recreational hunting in the recovery and conservation of the wild turkey (Meleagris gallopavo spp.) in North America International Journal of Environmental Studies. DOI: 10.1080/00207233.2015.1022998  0.01
2015 Hughes TAC, Lee J. A New Test for Short Memory in Long Memory Time Series American Statistician. 69: 182-190. DOI: 10.1080/00031305.2015.1056829  0.01
2015 Allaert F, Gentile G, Baes M, De Geyter G, Hughes TM, Lewis F, Bianchi S, De Looze I, Fritz J, Holwerda BW, Verstappen J, Viaene S. HERschel Observations of Edge-on Spirals (HEROES): II. Tilted-ring modelling of the atomic gas disks Astronomy and Astrophysics. 582. DOI: 10.1051/0004-6361/201526667  0.01
2015 Viaene S, De Geyter G, Baes M, Fritz J, Bendo GJ, Boquien M, Boselli A, Bianchi S, Cortese L, Côté P, Cuillandre JC, De Looze I, Di Serego Alighieri S, Ferrarese L, Gwyn SDJ, ... Hughes TM, et al. NGC 4370: A case study for testing our ability to infer dust distribution and mass in nearby galaxies Astronomy and Astrophysics. 579. DOI: 10.1051/0004-6361/201526147  0.01
2015 Boselli A, Fossati M, Gavazzi G, Ciesla L, Buat V, Boissier S, Hughes TM. Hα imaging of the Herschel Reference Survey: The star formation properties of a volume-limited, K-band-selected sample of nearby late-type galaxies Astronomy and Astrophysics. 579. DOI: 10.1051/0004-6361/201525712  0.01
2015 Cormier D, Madden SC, Lebouteiller V, Abel N, Hony S, Galliano F, Rémy-Ruyer A, Bigiel F, Baes M, Boselli A, Chevance M, Cooray A, De Looze I, Doublier V, Galametz M, ... Hughes T, et al. The Herschel Dwarf Galaxy Survey: I. Properties of the low-metallicity ISM from PACS spectroscopy Astronomy and Astrophysics. 578. DOI: 10.1051/0004-6361/201425207  0.01
2015 Grossi M, Hunt LK, Madden SC, Hughes TM, Auld R, Baes M, Bendo GJ, Bianchi S, Bizzocchi L, Boquien M, Boselli A, Clemens M, Corbelli E, Cortese L, Davies J, et al. The herschel virgo cluster survey: XVIII. Star-forming dwarf galaxies in a cluster environment Astronomy and Astrophysics. 574. DOI: 10.1051/0004-6361/201424866  0.01
2015 Hughes TM, Foyle K, Schirm MRP, Parkin TJ, De Looze I, Wilson CD, Bendo GJ, Baes M, Fritz J, Boselli A, Cooray A, Cormier D, Karczewski OL, Lebouteiller V, Lu N, et al. Insights into gas heating and cooling in the disc of NGC 891 from Herschel far-infrared spectroscopy Astronomy and Astrophysics. 575. DOI: 10.1051/0004-6361/201424732  0.01
2015 Pappalardo C, Bendo GJ, Bianchi S, Hunt L, Zibetti S, Corbelli E, Di Serego Alighieri S, Grossi M, Davies J, Baes M, De Looze I, Fritz J, Pohlen M, Smith MWL, Verstappen J, ... ... Hughes T, et al. The Herschel Virgo Cluster Survey XVII. SPIRE point-source catalogs and number counts Astronomy and Astrophysics. 573. DOI: 10.1051/0004-6361/201424549  0.01
2015 Wu R, Madden SC, Galliano F, Wilson CD, Kamenetzky J, Lee MY, Schirm M, Hony S, Lebouteiller V, Spinoglio L, Cormier D, Glenn J, Maloney PR, Pereira-Santaella M, Rémy-Ruyer A, ... ... Hughes TM, et al. Spatially resolved physical conditions of molecular gas and potential star formation tracers in M83, revealed by the Herschel SPIRE FTS Astronomy and Astrophysics. 575. DOI: 10.1051/0004-6361/201423847  0.01
2015 Peng S, Hartley PG, Hughes TC, Guo Q. Enhancing thermal stability and mechanical properties of lyotropic liquid crystals through incorporation of a polymerizable surfactant Soft Matter. 11: 6318-6326. DOI: 10.1039/c5sm01646k  0.01
2015 Qie F, Astolfo A, Wickramaratna M, Behe M, Evans MDM, Hughes TC, Hao X, Tan T. Self-assembled gold coating enhances X-ray imaging of alginate microcapsules Nanoscale. 7: 2480-2488. DOI: 10.1039/c4nr06692h  0.01
2015 Drobizhev M, Callis PR, Nifosì R, Wicks G, Stoltzfus C, Barnett L, Hughes TE, Sullivan P, Rebane A. Long-and Short-Range Electrostatic Fields in GFP Mutants: Implications for Spectral Tuning Scientific Reports. 5. DOI: 10.1038/srep13223  0.01
2015 Stoltzfus CR, Barnett LM, Drobizhev M, Wicks G, Mikhaylov A, Hughes TE, Rebane A. Two-photon directed evolution of green fluorescent proteins Scientific Reports. 5. DOI: 10.1038/srep11968  0.01
2015 Kojetin DJ, Matta-Camacho E, Hughes TS, Srinivasan S, Nwachukwu JC, Cavett V, Nowak J, Chalmers MJ, Marciano DP, Kamenecka TM, Shulman AI, Rance M, Griffin PR, Bruning JB, Nettles KW. Structural mechanism for signal transduction in RXR nuclear receptor heterodimers Nature Communications. 6. DOI: 10.1038/ncomms9013  0.01
2015 Hughes TP, Day JC, Brodie J. Securing the future of the Great Barrier Reef Nature Climate Change. 5: 508-511. DOI: 10.1038/nclimate2604  0.01
2015 Aranda F, Matthews AK, Hughes TL, Muramatsu N, Wilsnack SC, Johnson TP, Riley BB. Coming out in color: Racial/ethnic differences in the relationship between level of sexual identity disclosure and depression among lesbians Cultural Diversity and Ethnic Minority Psychology. 21: 247-257. DOI: 10.1037/a0037644  0.01
2015 Stanwix PL, Locke CR, Hughes TJ, Johns ML, Goodwin ARH, Marsh KN, May EF. Viscosity of {xCH4 + (1 - X)C3H8} with x = 0.949 for temperatures between (200 and 423) K and pressures between (10 and 31) MPa Journal of Chemical and Engineering Data. 60: 118-123. DOI: 10.1021/je500857w  0.01
2015 Liu Y, Muir BW, Waddington LJ, Hinton TM, Moffat BA, Hao X, Qiu J, Hughes TC. Colloidally Stabilized Magnetic Carbon Nanotubes Providing MRI Contrast in Mouse Liver Tumors Biomacromolecules. 16: 790-797. DOI: 10.1021/bm501706x  0.01
2015 Fawcett AS, Hughes TC, Zepeda-Velazquez L, Brook MA. Phototunable Cross-Linked Polysiloxanes Macromolecules. 48: 6499-6507. DOI: 10.1021/acs.macromol.5b01085  0.01
2015 Locke CR, Fang D, Stanwix PL, Hughes TJ, Xiao G, Johns ML, Goodwin ARH, Marsh KN, May EF. Viscosity and dew point measurements of {xCH4 + (1 - X)C4H10} for x = 0.9484 with a vibrating-wire viscometer Journal of Chemical and Engineering Data. 60: 3688-3695. DOI: 10.1021/acs.jced.5b00635  0.01
2015 May EF, Guo JY, Oakley JH, Hughes TJ, Graham BF, Marsh KN, Huang SH. Reference quality vapor-liquid equilibrium data for the binary systems methane + ethane, + propane, + butane, and + 2-methylpropane, at temperatures from (203 to 273) K and pressures to 9 MPa Journal of Chemical and Engineering Data. 60: 3606-3620. DOI: 10.1021/acs.jced.5b00610  0.01
2015 Hughes TB, Miller GP, Swamidass SJ. Site of reactivity models predict molecular reactivity of diverse chemicals with glutathione Chemical Research in Toxicology. 28: 797-809. DOI: 10.1021/acs.chemrestox.5b00017  0.01
2015 Mihailidis S, Bockmann M, McConnell E, Hughes T, Van Beijsterveldt TCEM, Boomsma DI, McMaster M, Townsend G. The Influence of Chorion Type on Health Measures at Birth and Dental Development in Australian and Dutch Twins: A Comparative Study Twin Research and Human Genetics. 18: 368-374. DOI: 10.1017/thg.2015.43  0.01
2015 Hughes TH, Smith MC. Controllability of linear passive network behaviors Systems and Control Letters. DOI: 10.1016/j.sysconle.2015.09.011  0.01
2015 Hughes TJ, Kandathil SM, Popelier PLA. Accurate prediction of polarised high order electrostatic interactions for hydrogen bonded complexes using the machine learning method kriging Spectrochimica Acta - Part a: Molecular and Biomolecular Spectroscopy. 136: 32-41. DOI: 10.1016/j.saa.2013.10.059  0.01
2015 Barlow KJ, Bernabeu V, Hao X, Hughes TC, Hutt OE, Polyzos A, Turner KA, Moad G. Triphenylphosphine-grafted, RAFT-synthesised, porous monoliths as catalysts for Michael addition in flow synthesis Reactive and Functional Polymers. 96: 89-96. DOI: 10.1016/j.reactfunctpolym.2015.09.008  0.01
2015 Locke CR, Stanwix PL, Hughes TJ, Johns ML, Goodwin ARH, Marsh KN, Galliero G, May EF. Viscosity of {xCO2 + (1 - X)CH4} with x = 0.5174 for temperatures between (229 and 348) K and pressures between (1 and 32) MPa Journal of Chemical Thermodynamics. 87: 162-167. DOI: 10.1016/j.jct.2015.03.007  0.01
2015 Hughes TJ, Kandil ME, Graham BF, Marsh KN, Huang SH, May EF. Phase equilibrium measurements of (methane + benzene) and (methane + methylbenzene) at temperatures from (188 to 348) K and pressures to 13 MPa Journal of Chemical Thermodynamics. 85: 141-147. DOI: 10.1016/j.jct.2014.12.031  0.01
2015 Valera-Medina A, Morris S, Runyon J, Pugh DG, Marsh R, Beasley P, Hughes T. Ammonia, Methane and Hydrogen for Gas Turbines Energy Procedia. 75: 118-123. DOI: 10.1016/j.egypro.2015.07.205  0.01
2015 Fischer J, Gardner TA, Bennett EM, Balvanera P, Biggs R, Carpenter S, Daw T, Folke C, Hill R, Hughes TP, Luthe T, Maass M, Meacham M, Norström AV, Peterson G, et al. Advancing sustainability through mainstreaming a social-ecological systems perspective Current Opinion in Environmental Sustainability. 14: 144-149. DOI: 10.1016/j.cosust.2015.06.002  0.01
2015 Barmatov E, Hughes T, Nagl M. Efficiency of film-forming corrosion inhibitors in strong hydrochloric acid under laminar and turbulent flow conditions Corrosion Science. 92: 85-94. DOI: 10.1016/j.corsci.2014.11.038  0.01
2015 Hughes TJ, Popelier PLA. Where does charge reside in amino acids? The effect of side-chain protonation state on the atomic charges of Asp, Glu, Lys, His and Arg Computational and Theoretical Chemistry. 1053: 298-304. DOI: 10.1016/j.comptc.2014.07.020  0.01
2015 Liu J, Landis CM, Gomez H, Hughes TJR. Liquid-vapor phase transition: Thermomechanical theory, entropy stable numerical formulation, and boiling simulations Computer Methods in Applied Mechanics and Engineering. 297: 476-553. DOI: 10.1016/j.cma.2015.09.007  0.01
2015 Kruse R, Nguyen-Thanh N, De Lorenzis L, Hughes TJR. Isogeometric collocation for large deformation elasticity and frictional contact problems Computer Methods in Applied Mechanics and Engineering. 296: 73-112. DOI: 10.1016/j.cma.2015.07.022  0.01
2015 Wei X, Zhang Y, Hughes TJR, Scott MA. Truncated hierarchical Catmull-Clark subdivision with local refinement Computer Methods in Applied Mechanics and Engineering. 291: 1-20. DOI: 10.1016/j.cma.2015.03.019  0.01
2015 Kiendl J, Auricchio F, Hughes TJR, Reali A. Single-variable formulations and isogeometric discretizations for shear deformable beams Computer Methods in Applied Mechanics and Engineering. 284: 988-1004. DOI: 10.1016/j.cma.2014.11.011  0.01
2015 Adam C, Hughes TJR, Bouabdallah S, Zarroug M, Maitournam H. Selective and reduced numerical integrations for NURBS-based isogeometric analysis Computer Methods in Applied Mechanics and Engineering. 284: 732-761. DOI: 10.1016/j.cma.2014.11.001  0.01
2015 Morganti S, Auricchio F, Benson DJ, Gambarin FI, Hartmann S, Hughes TJR, Reali A. Patient-specific isogeometric structural analysis of aortic valve closure Computer Methods in Applied Mechanics and Engineering. 284: 508-520. DOI: 10.1016/j.cma.2014.10.010  0.01
2015 Wan W, Zhao Z, Hughes TC, Qian B, Peng S, Hao X, Qiu J. Graphene oxide liquid crystal Pickering emulsions and their assemblies Carbon. 85: 16-23. DOI: 10.1016/j.carbon.2014.12.058  0.01
2015 Sarkisyan KS, Goryashchenko AS, Lidsky PV, Gorbachev DA, Bozhanova NG, Gorokhovatsky AY, Pereverzeva AR, Ryumina AP, Zherdeva VV, Savitsky AP, Solntsev KM, Bommarius AS, Sharonov GV, Lindquist JR, Drobizhev M, Hughes TE, et al. Green Fluorescent Protein with Anionic Tryptophan-Based Chromophore and Long Fluorescence Lifetime Biophysical Journal. 109: 380-389. DOI: 10.1016/j.bpj.2015.06.018  0.01
2015 Odeh R, Townsend G, Mihailidis S, Lähdesmäki R, Hughes T, Brook A. Infraocclusion: Dental development and associated dental variations in singletons and twins Archives of Oral Biology. 60: 1394-1402. DOI: 10.1016/j.archoralbio.2015.06.010  0.01
2015 Valera-Medina A, Marsh R, Runyon J, Pugh D, Beasley P, Hughes T, Bowen P. Ammonia-methane combustion in tangential swirl burners for gas turbine power generation Applied Energy. DOI: 10.1016/j.apenergy.2016.02.073  0.01
2015 Teo JCY, Hughes TL, Fradkin E. Theory of twist liquids: Gauging an anyonic symmetry Annals of Physics. 360: 349-445. DOI: 10.1016/j.aop.2015.05.012  0.01
2015 Ong J, Yeung D, Filshie R, Hughes TP, Nandurkar H. Imatinib-induced gastric antral vascular ectasia in three patients with chronic myeloid leukaemia International Journal of Hematology. DOI: 10.1007/s12185-015-1824-y  0.01
2015 Ross DM, Hughes TP. Discontinuation of therapy and treatment-free remission in CML Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia. 183-193. DOI: 10.1007/978-4-431-55714-2_12  0.01
2015 Szekely P, Knoblock CA, Slepicka J, Philpot A, Singh A, Yin C, Kapoor D, Natarajan P, Marcu D, Knight K, Stallard D, Karunamoorthy SS, Bojanapalli R, Minton S, Amanatullah B, ... Hughes T, et al. Building and using a knowledge graph to combat human trafficking Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 9367: 205-221. DOI: 10.1007/978-3-319-25010-6_12  0.01
2015 Tomaino M, Hughes TB. Nonoperative management of non-displaced acute scaphoid fracture Scaphoid Fractures and Nonunions: a Clinical Casebook. 9-19. DOI: 10.1007/978-3-319-18977-2_2  0.01
2015 Storace D, Rad MS, Han Z, Jin L, Cohen LB, Hughes T, Baker BJ, Sung U. Genetically encoded protein sensors of membrane potential Advances in Experimental Medicine and Biology. 859: 493-509. DOI: 10.1007/978-3-319-17641-3_20  0.01
2015 Hughes TM, Luu MB. Acute appendicitis Common Surgical Diseases: An Algorithmic Approach to Problem Solving, Third Edition. 169-171. DOI: 10.1007/978-1-4939-1565-1_42  0.01
2015 Schmitt AJ, Hughes TL, Herndon-Sobalvarro A. Creating University-Community Alliances to Build Internship Programs Psychology in the Schools. 52: 1042-1050. DOI: 10.1002/pits.21876  0.01
2015 Hughes TJ, Cardamone S, Popelier PLA. Realistic sampling of amino acid geometries for a multipolar polarizable force field Journal of Computational Chemistry. 36: 1844-1857. DOI: 10.1002/jcc.24006  0.01
2015 Townsend G, Brook A, Yong R, Hughes T. Tooth Classes, Field Concepts, and Symmetry A Companion to Dental Anthropology. 172-188. DOI: 10.1002/9781118845486.ch13  0.01
2015 Hughes T, Townsend G, Bockmann M. An Overview of Dental Genetics A Companion to Dental Anthropology. 123-141. DOI: 10.1002/9781118845486.ch10  0.01
2015 Gray S, Hughes TM. Gandhi's devotional political thought Philosophy East and West. 65: 375-400.  0.01
2015 Shaw G, Hughes T, Kelly C. Updating HF integration process, policy and guidance information for UK defence acquisition Contemporary Ergonomics and Human Factors 2015. 59-66.  0.01
2015 Hughes T, Kim J. Introduction: Intermedial aesthetics: Korean literature, film, and art Journal of Korean Studies. 20: 253-260.  0.01
2015 Szekely P, Knoblock CA, Slepicka J, Philpot A, Singh A, Yin C, Kapoor D, Natarajan P, Marcu D, Knight K, Stallard D, Karunamoorthy SS, Bojanapalli R, Minton S, Amanatullah B, ... Hughes T, et al. Demonstration paper: Using a knowledge graph to combat human trafficking Ceur Workshop Proceedings. 1486.  0.01
2014 Winterman E, Sharp K, McNamara G, Hughes T, Brown J. Support for mentors in clinical education. Nursing Times. 110: 21-3. PMID 26012069  0.01
2014 Hsu MC, Kamensky D, Bazilevs Y, Sacks MS, Hughes TJ. Fluid-structure interaction analysis of bioprosthetic heart valves: Significance of arterial wall deformation. Computational Mechanics. 54: 1055-1071. PMID 25580046 DOI: 10.1007/s00466-014-1059-4  0.01
2014 Espeland MA, Beavers KM, Gibbs BB, Johnson KC, Hughes TM, Baker LD, Jakicic J, Korytkowski M, Miller M, Bray GA. Ankle-brachial index and inter-artery blood pressure differences as predictors of cognitive function in overweight and obese older adults with diabetes: results from the Action for Health in Diabetes movement and memory study. International Journal of Geriatric Psychiatry. PMID 25546032 DOI: 10.1002/gps.4253  0.01
2014 Kaysen D, Kulesza M, Balsam KF, Rhew IC, Blayney JA, Lehavot K, Hughes TL. COPING AS A MEDIATOR OF INTERNALIZED HOMOPHOBIA AND PSYCHOLOGICAL DISTRESS AMONG YOUNG ADULT SEXUAL MINORITY WOMEN. Psychology of Sexual Orientation and Gender Diversity. 1: 225-233. PMID 25530980 DOI: 10.1037/sgd0000045  0.01
2014 Hughes TP, Bellwood DR, Connolly SR, Cornell HV, Karlson RH. Double jeopardy and global extinction risk in corals and reef fishes. Current Biology : Cb. 24: 2946-51. PMID 25454782 DOI: 10.1016/j.cub.2014.10.037  0.01
2014 Hughes T, Higginson I, Mann C. Tariffs in emergency care. British Journal of Hospital Medicine (London, England : 2005). 75: 631-6. PMID 25383433 DOI: 10.12968/hmed.2014.75.11.631  0.01
2014 Peng S, Xu C, Hughes TC, Zhang X. From nanodroplets by the ouzo effect to interfacial nanolenses. Langmuir : the Acs Journal of Surfaces and Colloids. 30: 12270-7. PMID 25262570 DOI: 10.1021/la502821m  0.01
2014 Olshen A, Tang M, Cortes J, Gonen M, Hughes T, Branford S, Quintás-Cardama A, Michor F. Dynamics of chronic myeloid leukemia response to dasatinib, nilotinib, and high-dose imatinib. Haematologica. 99: 1701-9. PMID 25216683 DOI: 10.3324/haematol.2013.085977  0.01
2014 Roberts KG, Li Y, Payne-Turner D, Harvey RC, Yang YL, Pei D, McCastlain K, Ding L, Lu C, Song G, Ma J, Becksfort J, Rusch M, Chen SC, Easton J, ... Hughes TP, et al. Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia. The New England Journal of Medicine. 371: 1005-15. PMID 25207766 DOI: 10.1056/NEJMoa1403088  0.01
2014 Parker WT, Phillis SR, Yeung DT, Hughes TP, Scott HS, Branford S. Many BCR-ABL1 compound mutations reported in chronic myeloid leukemia patients may actually be artifacts due to PCR-mediated recombination. Blood. 124: 153-5. PMID 24993880 DOI: 10.1182/blood-2014-05-573485  0.01
2014 Astolfo A, Qie F, Kibleur A, Hao X, Menk RH, Arfelli F, Rigon L, Hinton TM, Wickramaratna M, Tan T, Hughes TC. A simple way to track single gold-loaded alginate microcapsules using x-ray CT in small animal longitudinal studies. Nanomedicine : Nanotechnology, Biology, and Medicine. 10: 1821-8. PMID 24954384 DOI: 10.1016/j.nano.2014.06.008  0.01
2014 Hughes TP, Lipton JH, Spector N, Cervantes F, Pasquini R, Clementino NC, Dorlhiac Llacer PE, Schwarer AP, Mahon FX, Rea D, Branford S, Purkayastha D, Collins L, Szczudlo T, Leber B. Deep molecular responses achieved in patients with CML-CP who are switched to nilotinib after long-term imatinib. Blood. 124: 729-36. PMID 24948656 DOI: 10.1182/blood-2013-12-544015  0.01
2014 Branford S, Yeung DT, Parker WT, Roberts ND, Purins L, Braley JA, Altamura HK, Yeoman AL, Georgievski J, Jamison BA, Phillis S, Donaldson Z, Leong M, Fletcher L, Seymour JF, ... Hughes TP, et al. Prognosis for patients with CML and >10% BCR-ABL1 after 3 months of imatinib depends on the rate of BCR-ABL1 decline. Blood. 124: 511-8. PMID 24859364 DOI: 10.1182/blood-2014-03-566323  0.01
2014 Wirgenes KV, Tesli M, Inderhaug E, Athanasiu L, Agartz I, Melle I, Hughes T, Andreassen OA, Djurovic S. ANK3 gene expression in bipolar disorder and schizophrenia. The British Journal of Psychiatry : the Journal of Mental Science. 205: 244-5. PMID 24809399 DOI: 10.1192/bjp.bp.114.145433  0.01
2014 Ross DM, Hughes TP. How I determine if and when to recommend stopping tyrosine kinase inhibitor treatment for chronic myeloid leukaemia. British Journal of Haematology. 166: 3-11. PMID 24754670 DOI: 10.1111/bjh.12892  0.01
2014 Cardamone S, Hughes TJ, Popelier PL. Multipolar electrostatics. Physical Chemistry Chemical Physics : Pccp. 16: 10367-87. PMID 24741671 DOI: 10.1039/c3cp54829e  0.01
2014 Hughes TM, Kuller LH, Barinas-Mitchell EJ, McDade EM, Klunk WE, Cohen AD, Mathis CA, Dekosky ST, Price JC, Lopez OL. Arterial stiffness and β-amyloid progression in nondemented elderly adults. Jama Neurology. 71: 562-8. PMID 24687165 DOI: 10.1001/jamaneurol.2014.186  0.01
2014 Baccarani M, Druker BJ, Branford S, Kim DW, Pane F, Mongay L, Mone M, Ortmann CE, Kantarjian HM, Radich JP, Hughes TP, Cortes JE, Guilhot F. Long-term response to imatinib is not affected by the initial dose in patients with Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase: final update from the Tyrosine Kinase Inhibitor Optimization and Selectivity (TOPS) study. International Journal of Hematology. 99: 616-24. PMID 24658916 DOI: 10.1007/s12185-014-1566-2  0.01
2014 Yang R, Peng S, Hughes TC. Multistimuli responsive organogels based on a reactive azobenzene gelator. Soft Matter. 10: 2188-96. PMID 24652628 DOI: 10.1039/c3sm53145g  0.01
2014 Guidi G, Hughes TC, Whinton M, Brook MA, Sheardown H. The effect of silicone hydrogel contact lens composition on dexamethasone release. Journal of Biomaterials Applications. 29: 222-233. PMID 24556362 DOI: 10.1177/0885328214521253  0.01
2014 Hughes TP, Hochhaus A, Kantarjian HM, Cervantes F, Guilhot F, Niederwieser D, le Coutre PD, Rosti G, Ossenkoppele G, Lobo C, Shibayama H, Fan X, Menssen HD, Kemp C, Larson RA, et al. Safety and efficacy of switching to nilotinib 400 mg twice daily for patients with chronic myeloid leukemia in chronic phase with suboptimal response or failure on front-line imatinib or nilotinib 300 mg twice daily. Haematologica. 99: 1204-11. PMID 24532039 DOI: 10.3324/haematol.2013.091272  0.01
2014 Nievergall E, Ramshaw HS, Yong AS, Biondo M, Busfield SJ, Vairo G, Lopez AF, Hughes TP, White DL, Hiwase DK. Monoclonal antibody targeting of IL-3 receptor α with CSL362 effectively depletes CML progenitor and stem cells. Blood. 123: 1218-28. PMID 24363400 DOI: 10.1182/blood-2012-12-475194  0.01
2014 Hughes TP, Saglio G, Kantarjian HM, Guilhot F, Niederwieser D, Rosti G, Nakaseko C, De Souza CA, Kalaycio ME, Meier S, Fan X, Menssen HD, Larson RA, Hochhaus A. Early molecular response predicts outcomes in patients with chronic myeloid leukemia in chronic phase treated with frontline nilotinib or imatinib. Blood. 123: 1353-60. PMID 24335106 DOI: 10.1182/blood-2013-06-510396  0.01
2014 Hughes TM, Lopez OL, Evans RW, Kamboh MI, Williamson JD, Klunk WE, Mathis CA, Price JC, Cohen AD, Snitz BE, Dekosky ST, Kuller LH. Markers of cholesterol transport are associated with amyloid deposition in the brain. Neurobiology of Aging. 35: 802-7. PMID 24199960 DOI: 10.1016/j.neurobiolaging.2013.09.040  0.01
2014 Liu Y, Hughes TC, Muir BW, Waddington LJ, Gengenbach TR, Easton CD, Hinton TM, Moffat BA, Hao X, Qiu J. Water-dispersible magnetic carbon nanotubes as T2-weighted MRI contrast agents. Biomaterials. 35: 378-86. PMID 24120046 DOI: 10.1016/j.biomaterials.2013.09.079  0.01
2014 Jabbour EJ, Hughes TP, Cortés JE, Kantarjian HM, Hochhaus A. Potential mechanisms of disease progression and management of advanced-phase chronic myeloid leukemia. Leukemia & Lymphoma. 55: 1451-62. PMID 24050507 DOI: 10.3109/10428194.2013.845883  0.01
2014 Peng S, Guo Q, Hughes TC, Hartley PG. Reversible photorheological lyotropic liquid crystals. Langmuir : the Acs Journal of Surfaces and Colloids. 30: 866-72. PMID 24011217 DOI: 10.1021/la4030469  0.01
2013 Smart E, Hughes T, Smith L, Speirs V. Estrogen receptor β: putting a positive into triple negative breast cancer? Hormone Molecular Biology and Clinical Investigation. 16: 117-23. PMID 25436864 DOI: 10.1515/hmbci-2013-0042  0.01
2013 Hughes T, White D. Which TKI? An embarrassment of riches for chronic myeloid leukemia patients. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 2013: 168-75. PMID 24319178 DOI: 10.1182/asheducation-2013.1.168  0.01
2013 Hughes TM, Kuller LH, Barinas-Mitchell EJ, Mackey RH, McDade EM, Klunk WE, Aizenstein HJ, Cohen AD, Snitz BE, Mathis CA, Dekosky ST, Lopez OL. Pulse wave velocity is associated with β-amyloid deposition in the brains of very elderly adults. Neurology. 81: 1711-8. PMID 24132374 DOI: 10.1212/01.wnl.0000435301.64776.37  0.01
2013 Gallipoli P, Stobo J, Heaney N, Nicolini FE, Clark R, Wilson G, Tighe J, McLintock L, Hughes T, Michor F, Paul J, Drummond M, Holyoake TL. Safety and efficacy of pulsed imatinib with or without G-CSF versus continuous imatinib in chronic phase chronic myeloid leukaemia patients at 5 years follow-up. British Journal of Haematology. 163: 674-6. PMID 24032404 DOI: 10.1111/bjh.12532  0.01
2013 Hughes TM, Ryan CM, Aizenstein HJ, Nunley K, Gianaros PJ, Miller R, Costacou T, Strotmeyer ES, Orchard TJ, Rosano C. Frontal gray matter atrophy in middle aged adults with type 1 diabetes is independent of cardiovascular risk factors and diabetes complications. Journal of Diabetes and Its Complications. 27: 558-64. PMID 23994432 DOI: 10.1016/j.jdiacomp.2013.07.001  0.01
2013 Baccarani M, Deininger MW, Rosti G, Hochhaus A, Soverini S, Apperley JF, Cervantes F, Clark RE, Cortes JE, Guilhot F, Hjorth-Hansen H, Hughes TP, Kantarjian HM, Kim DW, Larson RA, et al. European LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013. Blood. 122: 872-84. PMID 23803709 DOI: 10.1182/blood-2013-05-501569  0.01
2013 Ross DM, Branford S, Seymour JF, Schwarer AP, Arthur C, Yeung DT, Dang P, Goyne JM, Slader C, Filshie RJ, Mills AK, Melo JV, White DL, Grigg AP, Hughes TP. Safety and efficacy of imatinib cessation for CML patients with stable undetectable minimal residual disease: results from the TWISTER study. Blood. 122: 515-22. PMID 23704092 DOI: 10.1182/blood-2013-02-483750  0.01
2013 Debono M, Prema A, Hughes TJ, Bull M, Ross RJ, Newell-Price J. Visceral fat accumulation and postdexamethasone serum cortisol levels in patients with adrenal incidentaloma. The Journal of Clinical Endocrinology and Metabolism. 98: 2383-91. PMID 23633207 DOI: 10.1210/jc.2012-4276  0.01
2013 Stein AM, Martinelli G, Hughes TP, Müller MC, Beppu L, Gottardi E, Branford S, Soverini S, Woodman RC, Hochhaus A, Kim DW, Saglio G, Radich JP. Rapid initial decline in BCR-ABL1 is associated with superior responses to second-line nilotinib in patients with chronic-phase chronic myeloid leukemia. Bmc Cancer. 13: 173. PMID 23547655 DOI: 10.1186/1471-2407-13-173  0.01
2013 Hercus TR, Dhagat U, Kan WL, Broughton SE, Nero TL, Perugini M, Sandow JJ, D'Andrea RJ, Ekert PG, Hughes T, Parker MW, Lopez AF. Signalling by the βc family of cytokines. Cytokine & Growth Factor Reviews. 24: 189-201. PMID 23535386 DOI: 10.1016/j.cytogfr.2013.03.002  0.01
2013 Thomas D, Powell JA, Green BD, Barry EF, Ma Y, Woodcock J, Fitter S, Zannettino AC, Pitson SM, Hughes TP, Lopez AF, Shepherd PR, Wei AH, Ekert PG, Guthridge MA. Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. Plos Biology. 11: e1001515. PMID 23526884 DOI: 10.1371/journal.pbio.1001515  0.01
2013 Branford S, Yeung DT, Ross DM, Prime JA, Field CR, Altamura HK, Yeoman AL, Georgievski J, Jamison BA, Phillis S, Sullivan B, Briggs NE, Hertzberg M, Seymour JF, Reynolds J, Hughes TP, et al. Early molecular response and female sex strongly predict stable undetectable BCR-ABL1, the criteria for imatinib discontinuation in patients with CML. Blood. 121: 3818-24. PMID 23515925 DOI: 10.1182/blood-2012-10-462291  0.01
2013 Hochhaus A, Saglio G, Larson RA, Kim DW, Etienne G, Rosti G, De Souza C, Kurokawa M, Kalaycio ME, Hoenekopp A, Fan X, Shou Y, Kantarjian HM, Hughes TP. Nilotinib is associated with a reduced incidence of BCR-ABL mutations vs imatinib in patients with newly diagnosed chronic myeloid leukemia in chronic phase. Blood. 121: 3703-8. PMID 23502220 DOI: 10.1182/blood-2012-04-423418  0.01
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