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Andrew L. Hopkins - Publications

Affiliations: 
University of Dundee, Dundee, Scotland, United Kingdom 
Area:
Computational Chemistry
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Redhead MA, Owen CD, Brewitz L, Collette AH, Lukacik P, Strain-Damerell C, Robinson SW, Collins PM, Schäfer P, Swindells M, Radoux CJ, Hopkins IN, Fearon D, Douangamath A, von Delft F, ... ... Hopkins AL, et al. Publisher Correction: Bispecific repurposed medicines targeting the viral and immunological arms of COVID-19. Scientific Reports. 11: 19633. PMID 34584208 DOI: 10.1038/s41598-021-99041-1  0.457
2021 Redhead MA, Owen CD, Brewitz L, Collette AH, Lukacik P, Strain-Damerell C, Robinson SW, Collins PM, Schäfer P, Swindells M, Radoux CJ, Hopkins IN, Fearon D, Douangamath A, von Delft F, ... ... Hopkins AL, et al. Bispecific repurposed medicines targeting the viral and immunological arms of COVID-19. Scientific Reports. 11: 13208. PMID 34168183 DOI: 10.1038/s41598-021-92416-4  0.548
2015 Guidi A, Mansour NR, Paveley RA, Carruthers IM, Besnard J, Hopkins AL, Gilbert IH, Bickle QD. Application of RNAi to Genomic Drug Target Validation in Schistosomes. Plos Neglected Tropical Diseases. 9: e0003801. PMID 25992548 DOI: 10.1371/journal.pntd.0003801  0.692
2015 Besnard J, Jones PS, Hopkins AL, Pannifer AD. The Joint European Compound Library: boosting precompetitive research. Drug Discovery Today. 20: 181-6. PMID 25205347 DOI: 10.1016/j.drudis.2014.08.014  0.672
2014 Hopkins AL, Keserü GM, Leeson PD, Rees DC, Reynolds CH. The role of ligand efficiency metrics in drug discovery. Nature Reviews. Drug Discovery. 13: 105-21. PMID 24481311 DOI: 10.1038/nrd4163  0.422
2013 Aristotelous T, Ahn S, Shukla AK, Gawron S, Sassano MF, Kahsai AW, Wingler LM, Zhu X, Tripathi-Shukla P, Huang XP, Riley J, Besnard J, Read KD, Roth BL, Gilbert IH, ... Hopkins AL, et al. Discovery of β2 Adrenergic Receptor Ligands Using Biosensor Fragment Screening of Tagged Wild-Type Receptor. Acs Medicinal Chemistry Letters. 4: 1005-1010. PMID 24454993 DOI: 10.1021/Ml400312J  0.703
2012 Besnard J, Ruda GF, Setola V, Abecassis K, Rodriguiz RM, Huang XP, Norval S, Sassano MF, Shin AI, Webster LA, Simeons FR, Stojanovski L, Prat A, Seidah NG, Constam DB, ... ... Hopkins AL, et al. Automated design of ligands to polypharmacological profiles. Nature. 492: 215-20. PMID 23235874 DOI: 10.1038/Nature11691  0.724
2012 Paveley RA, Mansour NR, Hallyburton I, Bleicher LS, Benn AE, Mikic I, Guidi A, Gilbert IH, Hopkins AL, Bickle QD. Whole organism high-content screening by label-free, image-based Bayesian classification for parasitic diseases. Plos Neglected Tropical Diseases. 6: e1762. PMID 22860151 DOI: 10.1371/Journal.Pntd.0001762  0.328
2012 Bickerton GR, Paolini GV, Besnard J, Muresan S, Hopkins AL. Quantifying the chemical beauty of drugs. Nature Chemistry. 4: 90-8. PMID 22270643 DOI: 10.1038/nchem.1243  0.702
2011 Navratilova I, Hopkins AL. Emerging role of surface plasmon resonance in fragment-based drug discovery. Future Medicinal Chemistry. 3: 1809-20. PMID 22004086 DOI: 10.4155/fmc.11.128  0.351
2011 Orchard S, Al-Lazikani B, Bryant S, Clark D, Calder E, Dix I, Engkvist O, Forster M, Gaulton A, Gilson M, Glen R, Grigorov M, Hammond-Kosack K, Harland L, Hopkins A, et al. Minimum information about a bioactive entity (MIABE). Nature Reviews. Drug Discovery. 10: 661-9. PMID 21878981 DOI: 10.1038/Nrd3503  0.596
2011 Navratilova I, Besnard J, Hopkins AL. Screening for GPCR Ligands Using Surface Plasmon Resonance. Acs Medicinal Chemistry Letters. 2: 549-554. PMID 21765967 DOI: 10.1021/ml2000017  0.634
2011 Hopkins AL, Wyatt PG. Progress in neglected disease drug discovery. Current Topics in Medicinal Chemistry. 11: 1215. PMID 21401510  0.382
2011 Hopkins AL, Bickerton GR, Carruthers IM, Boyer SK, Rubin H, Overington JP. Rapid analysis of pharmacology for infectious diseases. Current Topics in Medicinal Chemistry. 11: 1292-300. PMID 21401504 DOI: 10.2174/156802611795429130  0.66
2010 Navratilova I, Hopkins AL. Fragment screening by surface plasmon resonance. Acs Medicinal Chemistry Letters. 1: 44-8. PMID 24900174 DOI: 10.1021/ml900002k  0.412
2010 Hopkins AL, Bickerton GR. Drug discovery: Know your chemical space. Nature Chemical Biology. 6: 482-3. PMID 20559312 DOI: 10.1038/nchembio.395  0.379
2010 Qi D, King RD, Hopkins AL, Bickerton GR, Soldatova LN. An ontology for description of drug discovery investigations. Journal of Integrative Bioinformatics. 7. PMID 20375446 DOI: 10.2390/Biecoll-Jib-2010-126  0.349
2010 Hopkins AL. Drug discovery: Predicting promiscuity. Nature. 462: 167-8. PMID 19907483 DOI: 10.1038/462167a  0.398
2008 Hopkins AL. Network pharmacology: the next paradigm in drug discovery. Nature Chemical Biology. 4: 682-90. PMID 18936753 DOI: 10.1038/nchembio.118  0.486
2008 Agüero F, Al-Lazikani B, Aslett M, Berriman M, Buckner FS, Campbell RK, Carmona S, Carruthers IM, Chan AW, Chen F, Crowther GJ, Doyle MA, Hertz-Fowler C, Hopkins AL, McAllister G, et al. Genomic-scale prioritization of drug targets: the TDR Targets database. Nature Reviews. Drug Discovery. 7: 900-7. PMID 18927591 DOI: 10.1038/Nrd2684  0.645
2006 Overington JP, Al-Lazikani B, Hopkins AL. How many drug targets are there? Nature Reviews. Drug Discovery. 5: 993-6. PMID 17139284 DOI: 10.1038/nrd2199  0.673
2006 Paolini GV, Shapland RH, van Hoorn WP, Mason JS, Hopkins AL. Global mapping of pharmacological space. Nature Biotechnology. 24: 805-15. PMID 16841068 DOI: 10.1038/nbt1228  0.352
2006 Hopkins AL, Mason JS, Overington JP. Can we rationally design promiscuous drugs? Current Opinion in Structural Biology. 16: 127-36. PMID 16442279 DOI: 10.1016/j.sbi.2006.01.013  0.661
2005 Lipinski C, Hopkins A. Navigating chemical space for biology and medicine. Nature. 432: 855-61. PMID 15602551 DOI: 10.1038/nature03193  0.365
2004 Freeman GA, Andrews Iii CW, Hopkins AL, Lowell GS, Schaller LT, Cowan JR, Gonzales SS, Koszalka GW, Hazen RJ, Boone LR, Ferris RG, Creech KL, Roberts GB, Short SA, Weaver K, et al. Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 2. Journal of Medicinal Chemistry. 47: 5923-36. PMID 15537347 DOI: 10.1021/jm040072r  0.43
2004 Hopkins AL, Ren J, Milton J, Hazen RJ, Chan JH, Stuart DI, Stammers DK. Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1. Journal of Medicinal Chemistry. 47: 5912-22. PMID 15537346 DOI: 10.1021/jm040071z  0.476
2003 Fauman EB, Hopkins AL, Groom CR. Structural bioinformatics in drug discovery. Methods of Biochemical Analysis. 44: 477-97. PMID 12647400 DOI: 10.1002/0471721204.ch23  0.422
2002 Hopkins AL, Groom CR. The druggable genome. Nature Reviews. Drug Discovery. 1: 727-30. PMID 12209152 DOI: 10.1038/nrd892  0.351
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