| Year |
Citation |
Score |
| 2015 |
Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, et al. Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology. 11: 625-31. PMID 26284661 DOI: 10.1038/Nchembio.1890 |
0.694 |
|
| 2012 |
Jones AC, Ottilie S, Eustáquio AS, Edwards DJ, Gerwick L, Moore BS, Gerwick WH. Evaluation of Streptomyces coelicolor A3(2) as a heterologous expression host for the cyanobacterial protein kinase C activator lyngbyatoxin A. The Febs Journal. 279: 1243-51. PMID 22314229 DOI: 10.1111/J.1742-4658.2012.08517.X |
0.591 |
|
| 2010 |
Huynh MU, Elston MC, Hernandez NM, Ball DB, Kajiyama S, Irie K, Gerwick WH, Edwards DJ. Enzymatic production of (-)-indolactam V by LtxB, a cytochrome P450 monooxygenase. Journal of Natural Products. 73: 71-4. PMID 20000453 DOI: 10.1021/Np900481A |
0.479 |
|
| 2008 |
Linington RG, Edwards DJ, Shuman CF, McPhail KL, Matainaho T, Gerwick WH. Symplocamide A, a potent cytotoxin and chymotrypsin inhibitor from the marine Cyanobacterium Symploca sp. Journal of Natural Products. 71: 22-7. PMID 18163584 DOI: 10.1021/Np070280X |
0.617 |
|
| 2006 |
Dorrestein PC, Blackhall J, Straight PD, Fischbach MA, Garneau-Tsodikova S, Edwards DJ, McLaughlin S, Lin M, Gerwick WH, Kolter R, Walsh CT, Kelleher NL. Activity screening of carrier domains within nonribosomal peptide synthetases using complex substrate mixtures and large molecule mass spectrometry. Biochemistry. 45: 1537-46. PMID 16460000 DOI: 10.1021/Bi052333K |
0.589 |
|
| 2005 |
Shen B, Chen M, Cheng Y, Du L, Edwards DJ, George NP, Huang Y, Oh T, Sanchez C, Tang G, Wendt-Pienkowski E, Yi F. Prerequisites for combinatorial biosynthesis: evolution of hybrid NRPS/PKS gene clusters. Ernst Schering Research Foundation Workshop. 107-26. PMID 15645718 |
0.456 |
|
| 2004 |
Edwards DJ, Gerwick WH. Lyngbyatoxin biosynthesis: sequence of biosynthetic gene cluster and identification of a novel aromatic prenyltransferase. Journal of the American Chemical Society. 126: 11432-3. PMID 15366877 DOI: 10.1021/Ja047876G |
0.671 |
|
| 2004 |
Edwards DJ, Marquez BL, Nogle LM, McPhail K, Goeger DE, Roberts MA, Gerwick WH. Structure and biosynthesis of the jamaicamides, new mixed polyketide-peptide neurotoxins from the marine cyanobacterium Lyngbya majuscula. Chemistry & Biology. 11: 817-33. PMID 15217615 DOI: 10.1016/J.Chembiol.2004.03.030 |
0.714 |
|
| 2002 |
Shen B, Du L, Sanchez C, Edwards DJ, Chen M, Murrell JM. Cloning and characterization of the bleomycin biosynthetic gene cluster from Streptomyces verticillus ATCC15003. Journal of Natural Products. 65: 422-31. PMID 11908996 DOI: 10.1021/Np010550Q |
0.73 |
|
| 2001 |
Shen B, Du L, Sanchez C, Edwards DJ, Chen M, Murrell JM. The biosynthetic gene cluster for the anticancer drug bleomycin from Streptomyces verticillus ATCC15003 as a model for hybrid peptide-polyketide natural product biosynthesis. Journal of Industrial Microbiology & Biotechnology. 27: 378-85. PMID 11774003 DOI: 10.1038/Sj.Jim.7000194 |
0.713 |
|
| 2001 |
Sánchez C, Du L, Edwards DJ, Toney MD, Shen B. Cloning and characterization of a phosphopantetheinyl transferase from Streptomyces verticillus ATCC15003, the producer of the hybrid peptide-polyketide antitumor drug bleomycin. Chemistry & Biology. 8: 725-38. PMID 11451672 DOI: 10.1016/S1074-5521(01)00047-3 |
0.669 |
|
| 2000 |
Du L, Sánchez C, Chen M, Edwards DJ, Shen B. The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide synthetases and a polyketide synthase. Chemistry & Biology. 7: 623-42. PMID 11048953 DOI: 10.1016/S1074-5521(00)00011-9 |
0.703 |
|
| 1999 |
Shen B, Du L, Sanchez C, Chen M, Edwards DJ. Bleomycin biosynthesis in Streptomyces verticillus ATCC15003: A model of hybrid peptide and polyketide biosynthesis Bioorganic Chemistry. 27: 155-171. DOI: 10.1006/Bioo.1998.1131 |
0.681 |
|
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