Patrick Mitchell - Publications

Affiliations: 
Fred Hutchinson Cancer Research Center, Seattle, WA, United States 

22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Tsu BV, Beierschmitt C, Ryan AP, Agarwal R, Mitchell PS, Daugherty MD. Diverse viral proteases activate the NLRP1 inflammasome. Elife. 10. PMID 33410748 DOI: 10.7554/eLife.60609  0.68
2020 Mitchell PS, Roncaioli JL, Turcotte EA, Goers L, Chavez RA, Lee AY, Lesser CF, Rauch I, Vance RE. NAIP-NLRC4-deficient mice are susceptible to shigellosis. Elife. 9. PMID 33074100 DOI: 10.7554/eLife.59022  0.68
2020 Daskalov A, Mitchell PS, Sandstrom A, Vance RE, Glass NL. Molecular characterization of a fungal gasdermin-like protein. Proceedings of the National Academy of Sciences of the United States of America. PMID 32703806 DOI: 10.1073/pnas.2004876117  0.68
2019 Mitchell PS, Sandstrom A, Vance RE. The NLRP1 inflammasome: new mechanistic insights and unresolved mysteries. Current Opinion in Immunology. 60: 37-45. PMID 31121538 DOI: 10.1016/j.coi.2019.04.015  0.68
2019 Sandstrom A, Mitchell PS, Goers L, Mu EW, Lesser CF, Vance RE. Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes. Science (New York, N.Y.). PMID 30872533 DOI: 10.1126/science.aau1330  0.68
2016 Chavarría-Smith J, Mitchell PS, Ho AM, Daugherty MD, Vance RE. Functional and Evolutionary Analyses Identify Proteolysis as a General Mechanism for NLRP1 Inflammasome Activation. Plos Pathogens. 12: e1006052. PMID 27926929 DOI: 10.1371/journal.ppat.1006052  0.68
2015 Mitchell PS, Young JM, Emerman M, Malik HS. Evolutionary Analyses Suggest a Function of MxB Immunity Proteins Beyond Lentivirus Restriction. Plos Pathogens. 11: e1005304. PMID 26658285 DOI: 10.1371/journal.ppat.1005304  0.56
2013 Huang JW, Wang Y, Dhillon KK, Calses P, Villegas E, Mitchell PS, Tewari M, Kemp CJ, Taniguchi T. Systematic screen identifies miRNAs that target RAD51 and RAD51D to enhance chemosensitivity. Molecular Cancer Research : McR. 11: 1564-73. PMID 24088786 DOI: 10.1158/1541-7786.MCR-13-0292  0.56
2013 Cheng HH, Mitchell PS, Kroh EM, Dowell AE, Chéry L, Siddiqui J, Nelson PS, Vessella RL, Knudsen BS, Chinnaiyan AM, Pienta KJ, Morrissey C, Tewari M. Circulating microRNA profiling identifies a subset of metastatic prostate cancer patients with evidence of cancer-associated hypoxia. Plos One. 8: e69239. PMID 23935962 DOI: 10.1371/journal.pone.0069239  0.56
2013 Mitchell PS, Emerman M, Malik HS. An evolutionary perspective on the broad antiviral specificity of MxA. Current Opinion in Microbiology. 16: 493-9. PMID 23725670 DOI: 10.1016/j.mib.2013.04.005  0.56
2012 Mitchell PS, Patzina C, Emerman M, Haller O, Malik HS, Kochs G. Evolution-guided identification of antiviral specificity determinants in the broadly acting interferon-induced innate immunity factor MxA. Cell Host & Microbe. 12: 598-604. PMID 23084925 DOI: 10.1016/j.chom.2012.09.005  0.56
2011 Wang Y, Huang JW, Li M, Cavenee WK, Mitchell PS, Zhou X, Tewari M, Furnari FB, Taniguchi T. MicroRNA-138 modulates DNA damage response by repressing histone H2AX expression. Molecular Cancer Research : McR. 9: 1100-11. PMID 21693595 DOI: 10.1158/1541-7786.MCR-11-0007  0.56
2011 Arroyo JD, Chevillet JR, Kroh EM, Ruf IK, Pritchard CC, Gibson DF, Mitchell PS, Bennett CF, Pogosova-Agadjanyan EL, Stirewalt DL, Tait JF, Tewari M. Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma. Proceedings of the National Academy of Sciences of the United States of America. 108: 5003-8. PMID 21383194 DOI: 10.1073/pnas.1019055108  0.56
2010 Wurz K, Garcia RL, Goff BA, Mitchell PS, Lee JH, Tewari M, Swisher EM. MiR-221 and MiR-222 alterations in sporadic ovarian carcinoma: Relationship to CDKN1B, CDKNIC and overall survival. Genes, Chromosomes & Cancer. 49: 577-84. PMID 20461750 DOI: 10.1002/gcc.20768  0.56
2010 Kroh EM, Parkin RK, Mitchell PS, Tewari M. Analysis of circulating microRNA biomarkers in plasma and serum using quantitative reverse transcription-PCR (qRT-PCR). Methods (San Diego, Calif.). 50: 298-301. PMID 20146939 DOI: 10.1016/j.ymeth.2010.01.032  0.56
2010 Kroh EM, Parkin RK, Mitchell PS, Tewari M. Corrigendum to "Analysis of circulating microRNA biomarkers in plasma and serum using quantitative reverse transcription-PCR (qRT-PCR)" [Methods 50 (2010) 298-301] Methods. 52: 268. DOI: 10.1016/j.ymeth.2010.04.011  0.56
2009 Knouf EC, Metzger MJ, Mitchell PS, Arroyo JD, Chevillet JR, Tewari M, Miller AD. Multiple integrated copies and high-level production of the human retrovirus XMRV (xenotropic murine leukemia virus-related virus) from 22Rv1 prostate carcinoma cells. Journal of Virology. 83: 7353-6. PMID 19403664 DOI: 10.1128/JVI.00546-09  0.56
2009 Wyman SK, Parkin RK, Mitchell PS, Fritz BR, O'Briant K, Godwin AK, Urban N, Drescher CW, Knudsen BS, Tewari M. Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries. Plos One. 4: e5311. PMID 19390579 DOI: 10.1371/journal.pone.0005311  0.56
2009 Kahn TR, Fong KK, Jordan B, Lek JC, Levitan R, Mitchell PS, Wood C, Hatcher ME. An FTIR investigation of flanking sequence effects on the structure and flexibility of DNA binding sites Biochemistry. 48: 1315-1321. PMID 19166330 DOI: 10.1021/bi8015235  0.56
2008 Mitchell PS, Parkin RK, Kroh EM, Fritz BR, Wyman SK, Pogosova-Agadjanyan EL, Peterson A, Noteboom J, O'Briant KC, Allen A, Lin DW, Urban N, Drescher CW, Knudsen BS, Stirewalt DL, et al. Circulating microRNAs as stable blood-based markers for cancer detection. Proceedings of the National Academy of Sciences of the United States of America. 105: 10513-8. PMID 18663219 DOI: 10.1073/pnas.0804549105  0.56
2008 Bar M, Wyman SK, Fritz BR, Qi J, Garg KS, Parkin RK, Kroh EM, Bendoraite A, Mitchell PS, Nelson AM, Ruzzo WL, Ware C, Radich JP, Gentleman R, Ruohola-Baker H, et al. MicroRNA discovery and profiling in human embryonic stem cells by deep sequencing of small RNA libraries. Stem Cells (Dayton, Ohio). 26: 2496-505. PMID 18583537 DOI: 10.1634/stemcells.2008-0356  0.56
2008 Grady WM, Parkin RK, Mitchell PS, Lee JH, Kim YH, Tsuchiya KD, Washington MK, Paraskeva C, Willson JKV, Kaz AM, Kroh EM, Allen A, Fritz BR, Markowitz SD, Tewari M. Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer Oncogene. 27: 3880-3888. PMID 18264139 DOI: 10.1038/onc.2008.10  0.56
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