Year |
Citation |
Score |
2020 |
Krause KL, Furneaux R, Benjes P, Brimble M, Davidson T, Denny W, Harris L, Hinkley S, Tyler P, Ussher JE, Ward V. The post-lockdown period should be used to acquire effective therapies for future resurgence in SARS-Cov-2 infections. The New Zealand Medical Journal. 133: 107-111. PMID 32325475 |
0.401 |
|
2010 |
Gainsford GJ, Furneaux RH, Tyler PC, Sauve A, Shramm VL. A synchrotron radiation study of the one-dimensional complex of sodium with (1S)-N-carboxylato-1-(9-deazaadenin-9-yl)-1,4-dideoxy-1,4-imino-D-ribitol, a member of the 'immucillin' family. Acta Crystallographica. Section C, Crystal Structure Communications. 66: m65-8. PMID 20203397 DOI: 10.1107/S0108270110002738 |
0.465 |
|
2010 |
Ferrier RJ, Blattner R, Field RA, Furneaux RH, Gardiner JM, Hoberg JO, Kartha KPR, Tilbrook DMG, Tyler PC, Wightman RH. ChemInform Abstract: Other Physical Methods [For Studying Carbohydrates] Cheminform. 33: no-no. DOI: 10.1002/chin.200250278 |
0.593 |
|
2010 |
Ferrier RJ, Blattner R, Field RA, Furneaux RH, Gardiner JM, Hoberg JO, Kartha KPR, Tilbrook DMG, Tyler PC, Wightman RH. ChemInform Abstract: Ethers and Anhydrosugars Cheminform. 33: no-no. DOI: 10.1002/chin.200241281 |
0.644 |
|
2010 |
Ferrier RJ, Blattner R, Field RA, Furneaux RH, Gardiner JM, Hoberg JO, Kartha KPR, Tilbrook DMG, Tyler PC, Wightman RH. ChemInform Abstract: Separatory and Analytical Methods for Sugars Cheminform. 33: no-no. DOI: 10.1002/chin.200240300 |
0.607 |
|
2010 |
Ferrier RJ, Blattner R, Field RA, Furneaux RH, Gardiner JM, Hoberg JO, Kartha KPR, Tilbrook DMG, Tyler PC, Wightman RH. ChemInform Abstract: Miscellaneous Nitrogen-Containing Derivatives Cheminform. 33: no-no. DOI: 10.1002/chin.200239275 |
0.657 |
|
2010 |
Ferrier RJ, Blattner R, Field RA, Furneaux RH, Gardiner JM, Hoberg JO, Kartha KPR, Tilbrook DMG, Tyler PC, Wightman RH. ChemInform Abstract: Thio-, Seleno- and Tellurosugars. Cheminform. 33: no-no. DOI: 10.1002/chin.200239274 |
0.637 |
|
2010 |
Ferrier RJ, Blattner R, Field RA, Furneaux RH, Gardiner JM, Hoberg JO, Kartha KPR, Tilbrook DMG, Tyler PC, Wightman RH. ChemInform Abstract: Unsaturated Derivatives. Cheminform. 33: no-no. DOI: 10.1002/chin.200239272 |
0.663 |
|
2010 |
Ferrier RJ, Blattner R, Field RA, Furneaux RH, Gardiner JM, Hoberg JO, Kartha KPR, Tilbrook DMG, Tyler PC, Wightman RH. ChemInform Abstract: Inorganic Derivatives. Cheminform. 33: no-no. DOI: 10.1002/chin.200239269 |
0.66 |
|
2010 |
Ferrier RJ, Blattner R, Field RA, Furneaux RH, Gardiner JM, Hoberg JO, Kartha KPR, Tilbrook DMG, Tyler PC, Wightman RH. ChemInform Abstract: Antibiotics. Cheminform. 33: no-no. DOI: 10.1002/chin.200239267 |
0.611 |
|
2010 |
FERRIER RJ, BLATTNER R, CLINCH K, FURNEAUX RH, GARDINER JM, TYLER PC, WIGHTMAN RH, WILLIAMS NR. ChemInform Abstract: NMR Spectroscopy and Conformational Features of Sugars Cheminform. 28: no-no. DOI: 10.1002/chin.199715332 |
0.611 |
|
2010 |
FURNEAUX RH, GAINSFORD GJ, MASON JM, TYLER PC, HARTLEY O, WINCHESTER BG. ChemInform Abstract: The Chemistry of Castanospermine. Part 5. Synthetic Modifications at C- 1 and C-7. Cheminform. 28: no-no. DOI: 10.1002/chin.199715207 |
0.453 |
|
2010 |
FERRIER RJ, BLATTNER R, CLINCH K, FURNEAUX RH, GARDINER JM, TYLER PC, WIGHTMAN RH, WILLIAMS NR. ChemInform Abstract: Separatory and Analytical Methods. Part 1. Chromatographic Methods Cheminform. 28: no-no. DOI: 10.1002/chin.199714339 |
0.589 |
|
2010 |
FERRIER RJ, BLATTNER R, CLINCH K, FURNEAUX RH, GARDINER JM, TYLER PC, WIGHTMAN RH, WILLIAMS NR. ChemInform Abstract: Unsaturated Derivatives of Furanoid Glycals Cheminform. 28: no-no. DOI: 10.1002/chin.199714294 |
0.663 |
|
2010 |
FERRIER RJ, BLATTNER R, CLINCH K, FURNEAUX RH, GARDINER JM, TYLER PC, WIGHTMAN RH, WILLIAMS NR. ChemInform Abstract: Inorganic Derivatives. Part 1. Carbon-Bonded Phosphorus Derivatives Cheminform. 28: no-no. DOI: 10.1002/chin.199714291 |
0.622 |
|
2010 |
FERRIER RJ, BLATTNER R, CLINCH K, FURNEAUX RH, GARDINER JM, TYLER PC, WIGHTMAN RH, WILLIAMS NR. ChemInform Abstract: Antibiotics. Part 1. Aminoglycosides and Aminocyclitol Derivatives Cheminform. 28: no-no. DOI: 10.1002/chin.199714289 |
0.639 |
|
2010 |
FURNEAUX RH, GAINSFORD GJ, MASON JM, TYLER PC, HARTLEY O, WINCHESTER BG. ChemInform Abstract: Chemistry of Castanospermine. Part 4. Synthetic Modifications at C-8. Cheminform. 27: no-no. DOI: 10.1002/chin.199611272 |
0.478 |
|
2010 |
FURNEAUX RH, MASON JM, TYLER PC. ChemInform Abstract: The Chemistry of Castanospermine. Part 3. Castanospermine-6-phosphate, an Unusual Route to a Novel Compound. Cheminform. 26: no-no. DOI: 10.1002/chin.199534245 |
0.49 |
|
2010 |
FURNEAUX RH, GAINSFORD GJ, MASON JM, TYLER PC. ChemInform Abstract: The Chemistry of Castanospermine. Part 1. Synthetic Modifications at C- 6. Cheminform. 25: no-no. DOI: 10.1002/chin.199429273 |
0.478 |
|
2010 |
FERRIER RJ, BLATTNER R, CLINCH K, FURNEAUX RH, TYLER PC, WIGHTMAN RH, WILLIAMS NR. ChemInform Abstract: Carbohydrate Chemistry. Monosaccharides, Disaccharides, and Specific Oligosaccharides. Volume 25. A Review of the Recent Literature Published During 1991. Cheminform. 25: no-no. DOI: 10.1002/chin.199418274 |
0.601 |
|
2009 |
Clinch K, Evans GB, Fröhlich RF, Furneaux RH, Kelly PM, Legentil L, Murkin AS, Li L, Schramm VL, Tyler PC, Woolhouse AD. Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase. Journal of Medicinal Chemistry. 52: 1126-43. PMID 19170524 DOI: 10.1021/Jm801421Q |
0.501 |
|
2008 |
Schramm VL, Gutierrez JA, Cordovano G, Basu I, Guha C, Belbin TJ, Evans GB, Tyler PC, Furneaux RH. Transition state analogues in quorum sensing and SAM recycling. Nucleic Acids Symposium Series (2004). 75-6. PMID 18776260 DOI: 10.1093/nass/nrn038 |
0.533 |
|
2008 |
Evans GB, Furneaux RH, Greatrex B, Murkin AS, Schramm VL, Tyler PC. Azetidine based transition state analogue inhibitors of N-ribosyl hydrolases and phosphorylases. Journal of Medicinal Chemistry. 51: 948-56. PMID 18251493 DOI: 10.1021/Jm701265N |
0.517 |
|
2008 |
Rinaldo-Matthis A, Murkin AS, Ramagopal UA, Clinch K, Mee SP, Evans GB, Tyler PC, Furneaux RH, Almo SC, Schramm VL. L-Enantiomers of transition state analogue inhibitors bound to human purine nucleoside phosphorylase. Journal of the American Chemical Society. 130: 842-4. PMID 18154341 DOI: 10.1021/Ja710733G |
0.52 |
|
2007 |
Gutierrez JA, Luo M, Singh V, Li L, Brown RL, Norris GE, Evans GB, Furneaux RH, Tyler PC, Painter GF, Lenz DH, Schramm VL. Picomolar inhibitors as transition-state probes of 5'-methylthioadenosine nucleosidases. Acs Chemical Biology. 2: 725-34. PMID 18030989 DOI: 10.1021/Cb700166Z |
0.515 |
|
2007 |
Evans GB, Furneaux RH, Kelly PM, Schramm VL, Tyler PC. Transition state analogue inhibitors of N-ribosyltransferases: new drugs by targeting nucleoside processing enzymes. Nucleic Acids Symposium Series (2004). 63-4. PMID 18029587 DOI: 10.1093/nass/nrm032 |
0.514 |
|
2007 |
Clinch K, Evans GB, Furneaux RH, Lenz DH, Mason JM, Mee SP, Tyler PC, Wilcox SJ. A practical synthesis of (3R,4R)-N-tert-butoxycarbonyl-4-hydroxymethylpyrrolidin-3-ol. Organic & Biomolecular Chemistry. 5: 2800-2. PMID 17700848 DOI: 10.1039/b708796a |
0.521 |
|
2007 |
Rinaldo-Matthis A, Wing C, Ghanem M, Deng H, Wu P, Gupta A, Tyler PC, Evans GB, Furneaux RH, Almo SC, Wang CC, Schramm VL. Inhibition and structure of Trichomonas vaginalis purine nucleoside phosphorylase with picomolar transition state analogues. Biochemistry. 46: 659-68. PMID 17223688 DOI: 10.1021/Bi061515R |
0.504 |
|
2006 |
Singh V, Shi W, Almo SC, Evans GB, Furneaux RH, Tyler PC, Painter GF, Lenz DH, Mee S, Zheng R, Schramm VL. Structure and inhibition of a quorum sensing target from Streptococcus pneumoniae. Biochemistry. 45: 12929-41. PMID 17059210 DOI: 10.1021/Bi061184I |
0.509 |
|
2006 |
White KL, Rades T, Furneaux RH, Tyler PC, Hook S. Mannosylated liposomes as antigen delivery vehicles for targeting to dendritic cells. The Journal of Pharmacy and Pharmacology. 58: 729-37. PMID 16734974 DOI: 10.1211/jpp.58.6.0003 |
0.408 |
|
2006 |
Taylor Ringia EA, Tyler PC, Evans GB, Furneaux RH, Murkin AS, Schramm VL. Transition state analogue discrimination by related purine nucleoside phosphorylases. Journal of the American Chemical Society. 128: 7126-7. PMID 16734442 DOI: 10.1021/ja061403n |
0.522 |
|
2006 |
Clinch K, Evans GB, Fleet GW, Furneaux RH, Johnson SW, Lenz DH, Mee SP, Rands PR, Schramm VL, Taylor Ringia EA, Tyler PC. Syntheses and bio-activities of the L-enantiomers of two potent transition state analogue inhibitors of purine nucleoside phosphorylases. Organic & Biomolecular Chemistry. 4: 1131-9. PMID 16525558 DOI: 10.1039/B517883E |
0.52 |
|
2005 |
Evans GB, Furneaux RH, Lenz DH, Painter GF, Schramm VL, Singh V, Tyler PC. Second generation transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase. Journal of Medicinal Chemistry. 48: 4679-89. PMID 16000004 DOI: 10.1021/Jm050269Z |
0.548 |
|
2005 |
Lewandowicz A, Ringia EA, Ting LM, Kim K, Tyler PC, Evans GB, Zubkova OV, Mee S, Painter GF, Lenz DH, Furneaux RH, Schramm VL. Energetic mapping of transition state analogue interactions with human and Plasmodium falciparum purine nucleoside phosphorylases. The Journal of Biological Chemistry. 280: 30320-8. PMID 15961383 DOI: 10.1074/Jbc.M505033200 |
0.522 |
|
2005 |
Singh V, Evans GB, Lenz DH, Mason JM, Clinch K, Mee S, Painter GF, Tyler PC, Furneaux RH, Lee JE, Howell PL, Schramm VL. Femtomolar transition state analogue inhibitors of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Escherichia coli. The Journal of Biological Chemistry. 280: 18265-73. PMID 15749708 DOI: 10.1074/Jbc.M414472200 |
0.535 |
|
2005 |
Lee JE, Singh V, Evans GB, Tyler PC, Furneaux RH, Cornell KA, Riscoe MK, Schramm VL, Howell PL. Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase. The Journal of Biological Chemistry. 280: 18274-82. PMID 15746096 DOI: 10.1074/Jbc.M414471200 |
0.533 |
|
2005 |
Ting LM, Shi W, Lewandowicz A, Singh V, Mwakingwe A, Birck MR, Ringia EA, Bench G, Madrid DC, Tyler PC, Evans GB, Furneaux RH, Schramm VL, Kim K. Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins. The Journal of Biological Chemistry. 280: 9547-54. PMID 15576366 DOI: 10.1074/Jbc.M412693200 |
0.508 |
|
2004 |
Furneaux RH, Gainsford GJ, Mason JM, Tyler PC. The chemistry of castanospermine. Direct oxidation of the tetraacetate to the corresponding gamma-lactam. Carbohydrate Research. 339: 1747-51. PMID 15220084 DOI: 10.1016/j.carres.2004.05.006 |
0.445 |
|
2004 |
Evans GB, Furneaux RH, Schramm VL, Singh V, Tyler PC. Targeting the polyamine pathway with transition-state analogue inhibitors of 5'-methylthioadenosine phosphorylase. Journal of Medicinal Chemistry. 47: 3275-81. PMID 15163207 DOI: 10.1021/Jm0306475 |
0.531 |
|
2004 |
Zhou GC, Parikh SL, Tyler PC, Evans GB, Furneaux RH, Zubkova OV, Benjes PA, Schramm VL. Inhibitors of ADP-ribosylating bacterial toxins based on oxacarbenium ion character at their transition states. Journal of the American Chemical Society. 126: 5690-8. PMID 15125661 DOI: 10.1021/Ja038159+ |
0.526 |
|
2004 |
Roday S, Amukele T, Evans GB, Tyler PC, Furneaux RH, Schramm VL. Inhibition of ricin A-chain with pyrrolidine mimics of the oxacarbenium ion transition state. Biochemistry. 43: 4923-33. PMID 15109250 DOI: 10.1021/bi0498499 |
0.535 |
|
2004 |
Evans GB, Furneaux RH, Hausler H, Larsen JS, Tyler PC. Imino-C-nucleoside synthesis: heteroaryl lithium carbanion additions to a carbohydrate cyclic imine and nitrone. The Journal of Organic Chemistry. 69: 2217-20. PMID 15058979 DOI: 10.1021/jo035744k |
0.504 |
|
2004 |
Shi W, Ting LM, Kicska GA, Lewandowicz A, Tyler PC, Evans GB, Furneaux RH, Kim K, Almo SC, Schramm VL. Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function. The Journal of Biological Chemistry. 279: 18103-6. PMID 14982926 DOI: 10.1074/Jbc.C400068200 |
0.512 |
|
2004 |
Deng H, Lewandowicz A, Cahill SM, Furneaux RH, Tyler PC, Girvin ME, Callender RH, Schramm VL. Assignment of downfield proton resonances in purine nucleoside phosphorylase immucillin-H complex by saturation-transferred NOEs. Biochemistry. 43: 1980-7. PMID 14967038 DOI: 10.1021/Bi0358115 |
0.462 |
|
2004 |
Singh V, Shi W, Evans GB, Tyler PC, Furneaux RH, Almo SC, Schramm VL. Picomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-A. Biochemistry. 43: 9-18. PMID 14705926 DOI: 10.1021/Bi0358420 |
0.536 |
|
2003 |
Evans GB, Furneaux RH, Lewandowicz A, Schramm VL, Tyler PC. Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase. Journal of Medicinal Chemistry. 46: 5271-6. PMID 14613329 DOI: 10.1021/Jm030305Z |
0.544 |
|
2003 |
Evans GB, Furneaux RH, Tyler PC, Schramm VL. Synthesis of a transition state analogue inhibitor of purine nucleoside phosphorylase via the Mannich reaction. Organic Letters. 5: 3639-40. PMID 14507192 DOI: 10.1021/ol035293q |
0.512 |
|
2003 |
Evans GB, Furneaux RH, Lewandowicz A, Schramm VL, Tyler PC. Exploring structure-activity relationships of transition state analogues of human purine nucleoside phosphorylase. Journal of Medicinal Chemistry. 46: 3412-23. PMID 12852771 DOI: 10.1021/Jm030145R |
0.534 |
|
2003 |
Lewandowicz A, Tyler PC, Evans GB, Furneaux RH, Schramm VL. Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase. The Journal of Biological Chemistry. 278: 31465-8. PMID 12842889 DOI: 10.1074/jbc.C300259200 |
0.522 |
|
2003 |
Lewandowicz A, Shi W, Evans GB, Tyler PC, Furneaux RH, Basso LA, Santos DS, Almo SC, Schramm VL. Over-the-barrier transition state analogues and crystal structure with Mycobacterium tuberculosis purine nucleoside phosphorylase. Biochemistry. 42: 6057-66. PMID 12755607 DOI: 10.1021/Bi0343830 |
0.526 |
|
2003 |
Sauve AA, Cahill SM, Zech SG, Basso LA, Lewandowicz A, Santos DS, Grubmeyer C, Evans GB, Furneaux RH, Tyler PC, McDermott A, Girvin ME, Schramm VL. Ionic states of substrates and transition state analogues at the catalytic sites of N-ribosyltransferases. Biochemistry. 42: 5694-705. PMID 12741826 DOI: 10.1021/Bi034003A |
0.531 |
|
2003 |
Evans GB, Furneaux RH, Gainsford GJ, Hanson JC, Kicska GA, Sauve AA, Schramm VL, Tyler PC. 8-Aza-immucillins as transition-state analogue inhibitors of purine nucleoside phosphorylase and nucleoside hydrolases. Journal of Medicinal Chemistry. 46: 155-60. PMID 12502369 DOI: 10.1021/jm0203332 |
0.545 |
|
2003 |
Furneaux RH, Gainsford GJ, Mason JM, Tyler PC. (1R,2R,3S,5R,6R,7S,9aR,10aR)-4a,8a-diaza-perhydroanthracene-1,2,3,5,6, 7-hexaol Acta Crystallographica Section E: Structure Reports Online. 59: o1370-o1371. DOI: 10.1107/S1600536803018397 |
0.397 |
|
2002 |
Kicska GA, Tyler PC, Evans GB, Furneaux RH, Shi W, Fedorov A, Lewandowicz A, Cahill SM, Almo SC, Schramm VL. Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase. Biochemistry. 41: 14489-98. PMID 12463747 DOI: 10.1021/Bi026636F |
0.498 |
|
2002 |
Clinch K, Evans GB, Furneaux RH, Rendle PM, Rhodes PL, Roberton AM, Rosendale DI, Tyler PC, Wright DP. Synthesis and utility of sulfated chromogenic carbohydrate model substrates for measuring activities of mucin-desulfating enzymes. Carbohydrate Research. 337: 1095-111. PMID 12062525 DOI: 10.1016/S0008-6215(02)00104-0 |
0.445 |
|
2002 |
Kicska GA, Tyler PC, Evans GB, Furneaux RH, Kim K, Schramm VL. Transition state analogue inhibitors of purine nucleoside phosphorylase from Plasmodium falciparum. The Journal of Biological Chemistry. 277: 3219-25. PMID 11707439 DOI: 10.1074/Jbc.M105905200 |
0.477 |
|
2002 |
Kicska GA, Tyler PC, Evans GB, Furneaux RH, Schramm VL, Kim K. Purine-less death in Plasmodium falciparum induced by immucillin-H, a transition state analogue of purine nucleoside phosphorylase. The Journal of Biological Chemistry. 277: 3226-31. PMID 11706018 DOI: 10.1074/Jbc.M105906200 |
0.475 |
|
2002 |
Furneaux RH, Pakulski Z, Tyler PC. New mannotriosides and trimannosides as potential ligands for mannose-specific binding proteins Canadian Journal of Chemistry. 80: 964-972. DOI: 10.1139/v02-120 |
0.415 |
|
2002 |
Clinch K, Evans GB, Furneaux RH, Rendle PM, Rhodes PL, Roberton AM, Rosendale DI, Tyler PC, Wright DP. Corrigendum to “Synthesis and utility of sulfated chromogenic carbohydrate model substrates for measuring activities of mucin-desulfating enzymes” Carbohydrate Research. 337: 2513. DOI: 10.1016/S0008-6215(02)00313-0 |
0.42 |
|
2001 |
Evans GB, Furneaux RH, Hutchison TL, Kezar HS, Morris PE, Schramm VL, Tyler PC. Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine: convergent synthesis of the aza-C-nucleoside immucillins. The Journal of Organic Chemistry. 66: 5723-30. PMID 11511245 DOI: 10.1021/jo0155613 |
0.528 |
|
2001 |
Shi W, Basso LA, Santos DS, Tyler PC, Furneaux RH, Blanchard JS, Almo SC, Schramm VL. Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces. Biochemistry. 40: 8204-15. PMID 11444966 DOI: 10.1021/Bi010585P |
0.483 |
|
2001 |
Basso LA, Santos DS, Shi W, Furneaux RH, Tyler PC, Schramm VL, Blanchard JS. Purine nucleoside phosphorylase from Mycobacterium tuberculosis. Analysis of inhibition by a transition-state analogue and dissection by parts. Biochemistry. 40: 8196-203. PMID 11444965 DOI: 10.1021/Bi010584X |
0.475 |
|
2001 |
Tanaka KS, Chen XY, Ichikawa Y, Tyler PC, Furneaux RH, Schramm VL. Ricin A-chain inhibitors resembling the oxacarbenium ion transition state. Biochemistry. 40: 6845-51. PMID 11389598 DOI: 10.1021/Bi010499P |
0.475 |
|
2001 |
Kicska GA, Long L, Hörig H, Fairchild C, Tyler PC, Furneaux RH, Schramm VL, Kaufman HL. Immucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 98: 4593-8. PMID 11287638 DOI: 10.1073/pnas.071050798 |
0.462 |
|
2001 |
Fedorov A, Shi W, Kicska G, Fedorov E, Tyler PC, Furneaux RH, Hanson JC, Gainsford GJ, Larese JZ, Schramm VL, Almo SC. Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis. Biochemistry. 40: 853-60. PMID 11170405 DOI: 10.1021/Bi002499F |
0.541 |
|
2000 |
Shi W, Munagala NR, Wang CC, Li CM, Tyler PC, Furneaux RH, Grubmeyer C, Schramm VL, Almo SC. Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,). Biochemistry. 39: 6781-90. PMID 10841757 DOI: 10.1021/Bi000128T |
0.489 |
|
2000 |
Gainsford GJ, Tyler PC, Furneaux RH. 1,7,8-Tri-O-acetyl-6-O-benzoylcastanospermine Acta Crystallographica Section C Crystal Structure Communications. 56: e394-e395. DOI: 10.1107/S0108270100010477 |
0.402 |
|
2000 |
Evans GB, Furneaux RH, Gainsford GJ, Schramm VL, Tyler PC. Synthesis of transition state analogue inhibitors for purine nucleoside phosphorylase and N-riboside hydrolases Tetrahedron. 56: 3053-3062. DOI: 10.1016/S0040-4020(00)00194-0 |
0.538 |
|
1999 |
Furneaux RH, Tyler PC. Improved Syntheses of 3H,5H-Pyrrolo[3,2-d]pyrimidines. The Journal of Organic Chemistry. 64: 8411-8412. PMID 11674769 DOI: 10.1021/jo990903e |
0.435 |
|
1999 |
Furneaux RH, Schramm VL, Tyler PC. Transition state analogue inhibitors of protozoan nucleoside hydrolases. Bioorganic & Medicinal Chemistry. 7: 2599-606. PMID 10632070 DOI: 10.1016/S0968-0896(99)00210-2 |
0.53 |
|
1999 |
Miles RW, Tyler PC, Evans GB, Furneaux RH, Parkin DW, Schramm VL. Iminoribitol transition state analogue inhibitors of protozoan nucleoside hydrolases. Biochemistry. 38: 13147-54. PMID 10529186 DOI: 10.1021/Bi990829U |
0.555 |
|
1999 |
Shi W, Li CM, Tyler PC, Furneaux RH, Cahill SM, Girvin ME, Grubmeyer C, Schramm VL, Almo SC. The 2.0 A structure of malarial purine phosphoribosyltransferase in complex with a transition-state analogue inhibitor. Biochemistry. 38: 9872-80. PMID 10433693 DOI: 10.1021/Bi990664P |
0.534 |
|
1999 |
Shi W, Li CM, Tyler PC, Furneaux RH, Grubmeyer C, Schramm VL, Almo SC. The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor. Nature Structural Biology. 6: 588-93. PMID 10360366 DOI: 10.1038/9376 |
0.527 |
|
1999 |
Li CM, Tyler PC, Furneaux RH, Kicska G, Xu Y, Grubmeyer C, Girvin ME, Schramm VL. Transition-state analogs as inhibitors of human and malarial hypoxanthine-guanine phosphoribosyltransferases. Nature Structural Biology. 6: 582-7. PMID 10360365 DOI: 10.1038/9367 |
0.539 |
|
1998 |
Miles RW, Tyler PC, Furneaux RH, Bagdassarian CK, Schramm VL. One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase. Biochemistry. 37: 8615-21. PMID 9628722 DOI: 10.1021/bi980658d |
0.543 |
|
1997 |
Parkin DW, Limberg G, Tyler PC, Furneaux RH, Chen XY, Schramm VL. Isozyme-specific transition state inhibitors for the trypanosomal nucleoside hydrolases. Biochemistry. 36: 3528-34. PMID 9132003 DOI: 10.1021/Bi962319V |
0.532 |
|
1997 |
Furneaux RH, Limberg G, Tyler PC, Schramm VL. Synthesis of transition state inhibitors for N-riboside hydrolases and transferases Tetrahedron. 53: 2915-2930. DOI: 10.1016/S0040-4020(96)01172-6 |
0.562 |
|
1997 |
Furneaux RH, Gainsford GJ, Mason JM, Tyler PC, Hartley O, Winchester BG. The chemistry of castanospermine, part V: Synthetic modifications at C-1 and C-7 Tetrahedron. 53: 245-268. DOI: 10.1016/S0040-4020(96)00967-2 |
0.426 |
|
1996 |
Mazzella LJ, Parkin DW, Tyler PC, Furneaux RH, Schramm VL. Mechanistic diagnoses of N-ribohydrolases and purine nucleoside phosphorylase Journal of the American Chemical Society. 118: 2111-2112. DOI: 10.1021/Ja953537Z |
0.424 |
|
1996 |
Gainsford GJ, Tyler PC, Furneaux RH. (1R,2S,4R)-2-benzyloxy-4-methoxy-5-(1-methylethyl)-6,8-dioxabicyclo[3.2.1] octane and (1R,2S,4R)-2-benzyloxy-4-methoxy-2-methyl-6,8-dioxabicyclo[3.2.1]octane Acta Crystallographica Section C: Crystal Structure Communications. 52: 1274-1277. |
0.408 |
|
1995 |
Gainsford GJ, Furneaux RH, Mason JM, Tyler PC. 1,6-Anhydro-4-O-benzyl-3-deoxy-2-O-methyl-β-D-ribo-hexopyranose and 1,6-Anhydro-4-O-benzyl-2-C-(2-cyanoethyl)-2,3-dideoxy-β-D-ribo-hexopyranose Acta Crystallographica Section C Crystal Structure Communications. 51: 2418-2421. DOI: 10.1107/S0108270195007256 |
0.437 |
|
1995 |
Furneaux RH, Mason JM, Tyler PC. The chemistry of castanospermine, part III:1,2 Castanospermine-6-phosphate, an unusual route to a novel compound Tetrahedron Letters. 36: 3055-3058. DOI: 10.1016/0040-4039(95)00425-C |
0.462 |
|
1994 |
Furneaux RH, Mason JM, Tyler PC. The chemistry of castanospermine, part II: Synthesis of deoxyfluoro analogues of castanospermine Tetrahedron Letters. 35: 3143-3146. DOI: 10.1016/S0040-4039(00)76852-3 |
0.462 |
|
1994 |
Blattner R, Furneaux RH, Kemmitt T, Tyler PC, Ferrier RJ, Tidén AK. Syntheses of the fungicide/insecticide allosamidin and a structural isomer Journal of the Chemical Society, Perkin Transactions 1. 3411-3421. |
0.622 |
|
1993 |
Furneaux RH, Tyler PC, Whitehouse LA. A short practical synthesis of deoxymannojirimycin from d-fructose Tetrahedron Letters. 34: 3613-3616. DOI: 10.1016/S0040-4039(00)73650-1 |
0.445 |
|
1993 |
Furneaux RH, Tyler PC, Whitehouse LA. Synthesis of 1,5-dideoxy-1,5-imino-d-galactitol from l-sorbose Tetrahedron Letters. 34: 3609-3612. DOI: 10.1016/S0040-4039(00)73649-5 |
0.451 |
|
1991 |
Furneaux RH, Gainsford GJ, Manson JM, Tyler PC. The chemistry of castanospermine, part I: synthetic modifications at C-6 Tetrahedron. 50: 2131-2160. DOI: 10.1016/S0040-4020(01)85075-4 |
0.448 |
|
1991 |
Blattner R, Furneaux RH, Mason JM, Tyler PC. 2-Benzyloxy-6,8-Dioxabicyclo[3.2.1]Octanes: New carbohydrate-derived herbicides Pesticide Science. 31: 419-435. DOI: 10.1002/ps.2780310403 |
0.467 |
|
1990 |
Henzell RF, Furneaux RH, Tyler PC. An evaluation of the herbicidal and plant growth regulatory activity of a novel class of carbohydrate-derived 6,8-dioxabicyclo[3.2.1]octanes Pesticide Science. 30: 59-66. DOI: 10.1002/ps.2780300107 |
0.418 |
|
1986 |
CHEW S, FERRIER RJ, PRASIT P, TYLER PC. ChemInform Abstract: Routes to Carbocyclic Compounds of Pharmaceutical Importance from Carbohydrates Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198627361 |
0.513 |
|
1985 |
Ferrier RJ, Tyler PC. Synthesis and photolysis of some carbohydrate 1,6-dienes Carbohydrate Research. 136: 249-258. DOI: 10.1016/0008-6215(85)85201-0 |
0.533 |
|
1985 |
FERRIER RJ, TYLER PC. ChemInform Abstract: UNSATURATED CARBOHYDRATES, PART 28. SYNTHESIS AND PHOTOLYSIS OF SOME CARBOHYDRATE 1,6-DIENES Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198533345 |
0.558 |
|
1985 |
Ferrier RJ, Schmidt P, Tyler PC. Unsaturated carbohydrates. Part 27. Synthesis of (-)-exo-brevicomin from a nona-3,8-dienulose derivative Journal of the Chemical Society, Perkin Transactions 1. 301-303. |
0.555 |
|
1985 |
Ferrier RJ, Tyler PC, Gainsford GJ. Functionalised carbocycles from carbohydrates. Part 7. A route to carbacyclin from a D-glucose derivative. X-ray crystal structure of 3-endo-benzoyloxy-2-exo-(1,3-diphenyl-1,3,2-diazaphospholan-2-yloxymethyl) -6-oxobicyclo[3.3.0]-octane Journal of the Chemical Society, Perkin Transactions 1. 295-300. |
0.486 |
|
1983 |
FERRIER RJ, FURNEAUX RH, PRASIT P, TYLER PC, BROWN KL, GAINSFORD GJ, DIEHL JW. ChemInform Abstract: UNSATURATED CARBOHYDRATES. PART 24. FUNCTIONALIZED CARBOCYCLES FROM CARBOHYDRATES. PART 2. THE SYNTHESIS OF 3-OXA-2-AZABICYCLO(3.3.0)OCTANES. X-RAY CRYSTAL STRUCTURE OF (1R,5S)-6-EXO,7-ENDO,8-EXO-TRIACETOXY-N-METHYL-4-ENDO-PHENYLTHIO- Chemischer Informationsdienst. 14. DOI: 10.1002/chin.198348213 |
0.633 |
|
1983 |
Farrier RJ, Furneaux RH, Prasit P, Tyler PC, Brown KL, Gainsford GJ, Diehl JW. Functionalised carbocycles from carbohydrates. Part 2. The synthesis of 3-oxa-2-azabicyclo[3.3.0]octanes. X-ray crystal structure of (1R,5S)-6-exo,7-endo,8-exo-triacetoxy-N-methyl-4-endo-phenylthio-3-oxa-2- azabicyclo[3.3.0]octane Journal of the Chemical Society, Perkin Transactions 1. 1621-1628. |
0.469 |
|
1983 |
Ferrier RJ, Prasit P, Tyler PC. Functionalised carbocycles from carbohydrates. Part 5. The synthesis of the epoxybicyclo[3.2.0]heptanone ethylene acetal prostaglandin intermediate Journal of the Chemical Society, Perkin Transactions 1. 1641-1644. |
0.54 |
|
1980 |
Ferrier RJ, Tyler PC. Photo-bromination of carbohydrate derivatives. Part 3. C-5 bromination of penta-O-benzoyl-α- and -β-D-glucopyranose; a route to D-xylo-hexos-5-ulose derivatives and α-L-idopyranosides Journal of the Chemical Society, Perkin Transactions 1. 1528-1534. |
0.504 |
|
1980 |
Blattner R, Ferrier RJ, Tyler PC. Unsaturated carbohydrates. Part 22. Alkenes from 5-bromohexopyranose derivatives Journal of the Chemical Society, Perkin Transactions 1. 1535-1539. |
0.537 |
|
1980 |
Ferrier RJ, Tyler PC. Photobromination of carbohydrate derivatives. Part 5. Preparation and reactions of (5S)-1,2,3,4-tetra-O-acetyl-5-bromo-β-D-xylopyranose; a new type of 'double-headed' nucleoside Journal of the Chemical Society, Perkin Transactions 1. 2767-2773. |
0.506 |
|
1980 |
Ferrier RJ, Tyler PC. Photobromination of carbohydrate derivatives. Part 4. Observations on some glucopyranoside esters; a simple route to aryl α-L-idopyranosides Journal of the Chemical Society, Perkin Transactions 1. 2762-2766. |
0.508 |
|
1978 |
Ferrier RJ, Tyler PC. Introduction, substitution, and elimination of bromine at C-5 of aldopyranose peresters Journal of the Chemical Society, Chemical Communications. 1019-1020. DOI: 10.1039/C39780001019 |
0.503 |
|
1977 |
Blattner R, Ferrier RJ, Tyler PC. Aspects of the tautomerism of 2-(d-galacto-1,2,3,4,5-pentahydroxypentyl)benzothiazoline Carbohydrate Research. 54: 199-208. DOI: 10.1016/S0008-6215(00)84810-7 |
0.457 |
|
1977 |
Ferrier RJ, Furneaux RH, Tyler PC. Observations on the possible application of glycosyl disulphides, sulphenic esters, and sulphones in the synthesis of glycosides Carbohydrate Research. 58: 397-404. DOI: 10.1016/S0008-6215(00)84366-9 |
0.644 |
|
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