Mark S. Marshall - Publications

Affiliations: 
Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Molecular Biology, Biochemistry

74 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Du J, Yan L, Torres R, Gong X, Bian H, Marugán C, Boehnke K, Baquero C, Hui YH, Chapman SC, Yang Y, Zeng Y, Bogner SM, Foreman RT, Capen A, ... ... Marshall MS, et al. Aurora A selective inhibitor LY3295668 leads to dominant mitotic arrest, apoptosis in cancer cells and shows potent preclinical antitumor efficacy. Molecular Cancer Therapeutics. PMID 31530649 DOI: 10.1158/1535-7163.Mct-18-0529  0.326
2018 Pandya PH, Bailey B, Elmi AE, Bates HR, Hemenway CN, Sinn AL, Bijangi-Vishehsaraei K, Saadatzadeh MR, Shannon HE, Ding J, Marshall MS, Ferguson MJ, Cheng L, Li L, Murray ME, et al. Abstract 3180: Preclinical validation of EZH2 as a therapeutic target in pediatric Ewing's sarcoma Cancer Research. 78: 3180-3180. DOI: 10.1158/1538-7445.Am2018-3180  0.313
2015 King C, Diaz HB, McNeely S, Barnard D, Dempsey J, Blosser W, Beckmann R, Barda D, Marshall MS. LY2606368 Causes Replication Catastrophe and Antitumor Effects through CHK1-Dependent Mechanisms. Molecular Cancer Therapeutics. 14: 2004-13. PMID 26141948 DOI: 10.1158/1535-7163.Mct-14-1037  0.316
2014 King C, Diaz H, Barnard D, Barda D, Clawson D, Blosser W, Cox K, Guo S, Marshall M. Characterization and preclinical development of LY2603618: a selective and potent Chk1 inhibitor. Investigational New Drugs. 32: 213-26. PMID 24114124 DOI: 10.1007/S10637-013-0036-7  0.354
2012 Wu W, Bi C, Bence AK, Um SL, Yan B, Starling JJ, Marshall MS, Beckmann RP. Abstract 1776: Antitumor activity of Chk1 inhibitor LY2606368 as a single agent in SW1990 human pancreas orthotopic tumor model Cancer Research. 72: 1776-1776. DOI: 10.1158/1538-7445.Am2012-1776  0.349
2011 McNeely SC, Burke TF, DurlandBusbice S, Barnard DS, Marshall MS, Bence AK, Beckmann RP. Abstract A108: LY2606368, a second generation Chk1 inhibitor, inhibits growth of ovarian carcinoma xenografts either as monotherapy or in combination with standard-of-care agents. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-A108  0.337
2009 Marshall M, Barda D, Barnard D, Cox K, Diaz HB, King C, Nutter S, Westin E. Abstract B248: Characterization and preclinical development of LCI‐1, a selective and potent Chk1 inhibitor in phase 1 clinical trials Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-B248  0.302
2005 Fan L, Yang X, Du J, Marshall M, Blanchard K, Ye X. A novel role of p38 alpha MAPK in mitotic progression independent of its kinase activity. Cell Cycle (Georgetown, Tex.). 4: 1616-24. PMID 16258274 DOI: 10.4161/Cc.4.11.2125  0.41
2005 Yip-Schneider MT, Nakshatri H, Sweeney CJ, Marshall MS, Wiebke EA, Schmidt CM. Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-kappa B pathway in pancreatic carcinoma cells. Molecular Cancer Therapeutics. 4: 587-94. PMID 15827332 DOI: 10.1158/1535-7163.Mct-04-0215  0.316
2004 Carter JH, Douglass LE, Deddens JA, Colligan BM, Bhatt TR, Pemberton JO, Konicek S, Hom J, Marshall M, Graff JR. Pak-1 expression increases with progression of colorectal carcinomas to metastasis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 3448-56. PMID 15161701 DOI: 10.1158/1078-0432.Ccr-03-0210  0.439
2004 Bhat-Nakshatri P, Campbell RA, Patel NM, Newton TR, King AJ, Marshall MS, Ali S, Nakshatri H. Tumour necrosis factor and PI3-kinase control oestrogen receptor alpha protein level and its transrepression function. British Journal of Cancer. 90: 853-9. PMID 14970864 DOI: 10.1038/Sj.Bjc.6601541  0.355
2003 Slack-Davis JK, Eblen ST, Zecevic M, Boerner SA, Tarcsafalvi A, Diaz HB, Marshall MS, Weber MJ, Parsons JT, Catling AD. PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation. The Journal of Cell Biology. 162: 281-91. PMID 12876277 DOI: 10.1083/Jcb.200212141  0.441
2003 Hurley JH, Zhang S, Bye LS, Marshall MS, DePaoli-Roach AA, Guan K, Fox AP, Yu L. Insulin signaling inhibits the 5-HT2C receptor in choroid plexus via MAP kinase. Bmc Neuroscience. 4: 10. PMID 12795815 DOI: 10.1186/1471-2202-4-10  0.382
2003 Corbit KC, Trakul N, Eves EM, Diaz B, Marshall M, Rosner MR. Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein. The Journal of Biological Chemistry. 278: 13061-8. PMID 12551925 DOI: 10.1074/Jbc.M210015200  0.328
2001 Gelfanov VM, Burgess GS, Litz-Jackson S, King AJ, Marshall MS, Nakshatri H, Boswell HS. Transformation of interleukin-3-dependent cells without participation of Stat5/bcl-xL: cooperation of akt with raf/erk leads to p65 nuclear factor kappaB-mediated antiapoptosis involving c-IAP2. Blood. 98: 2508-17. PMID 11588049 DOI: 10.1182/Blood.V98.8.2508  0.44
2001 Ingram DA, Hiatt K, King AJ, Fisher L, Shivakumar R, Derstine C, Wenning MJ, Diaz B, Travers JB, Hood A, Marshall M, Williams DA, Clapp DW. Hyperactivation of p21(ras) and the hematopoietic-specific Rho GTPase, Rac2, cooperate to alter the proliferation of neurofibromin-deficient mast cells in vivo and in vitro. The Journal of Experimental Medicine. 194: 57-69. PMID 11435472 DOI: 10.1084/Jem.194.1.57  0.48
2001 King AJ, Wireman RS, Hamilton M, Marshall MS. Phosphorylation site specificity of the Pak-mediated regulation of Raf-1 and cooperativity with Src. Febs Letters. 497: 6-14. PMID 11376654 DOI: 10.1016/S0014-5793(01)02425-5  0.417
2001 Yip-Schneider MT, Lin A, Marshall MS. Pancreatic tumor cells with mutant K-ras suppress ERK activity by MEK-dependent induction of MAP kinase phosphatase-2. Biochemical and Biophysical Research Communications. 280: 992-7. PMID 11162624 DOI: 10.1006/Bbrc.2001.4243  0.483
2000 Yip-Schneider MT, Miao W, Lin A, Barnard DS, Tzivion G, Marshall MS. Regulation of the Raf-1 kinase domain by phosphorylation and 14-3-3 association. The Biochemical Journal. 351: 151-9. PMID 10998357 DOI: 10.1042/0264-6021:3510151  0.421
2000 Yang FC, Kapur R, King AJ, Tao W, Kim C, Borneo J, Breese R, Marshall M, Dinauer MC, Williams DA. Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells. Immunity. 12: 557-68. PMID 10843388 DOI: 10.1016/S1074-7613(00)80207-1  0.35
2000 Chaudhary A, King WG, Mattaliano MD, Frost JA, Diaz B, Morrison DK, Cobb MH, Marshall MS, Brugge JS. Phosphatidylinositol 3-kinase regulates Raf1 through Pak phosphorylation of serine 338. Current Biology : Cb. 10: 551-4. PMID 10801448 DOI: 10.1016/S0960-9822(00)00475-9  0.411
2000 Sun H, King AJ, Diaz HB, Marshall MS. Regulation of the protein kinase Raf-1 by oncogenic Ras through phosphatidylinositol 3-kinase, Cdc42/Rac and Pak. Current Biology : Cb. 10: 281-4. PMID 10712905 DOI: 10.1016/S0960-9822(00)00359-6  0.662
2000 Shi ZQ, Yu DH, Park M, Marshall M, Feng GS. Molecular mechanism for the Shp-2 tyrosine phosphatase function in promoting growth factor stimulation of Erk activity. Molecular and Cellular Biology. 20: 1526-36. PMID 10669730 DOI: 10.1128/Mcb.20.5.1526-1536.2000  0.673
2000 Yip-Schneider MT, Barnard DS, Billings SD, Cheng L, Heilman DK, Lin A, Marshall SJ, Crowell PL, Marshall MS, Sweeney CJ. Cyclooxygenase-2 expression in human pancreatic adenocarcinomas. Carcinogenesis. 21: 139-46. PMID 10657949 DOI: 10.1093/Carcin/21.2.139  0.397
2000 King AJ, Sun H, Diaz B, Bernard D, Miao W, Bagrodia S, Marshall MS. Erratum: correction: The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338 Nature. 406: 439-439. DOI: 10.1038/35019122  0.388
1999 Yip-Schneider MT, Lin A, Barnard D, Sweeney CJ, Marshall MS. Lack of elevated MAP kinase (Erk) activity in pancreatic carcinomas despite oncogenic K-ras expression. International Journal of Oncology. 15: 271-9. PMID 10402237 DOI: 10.3892/Ijo.15.2.271  0.504
1998 King AJ, Sun H, Diaz B, Barnard D, Miao W, Bagrodia S, Marshall MS. The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338. Nature. 396: 180-3. PMID 9823899 DOI: 10.1038/24184  0.668
1998 Barnard D, Diaz B, Clawson D, Marshall M. Oncogenes, growth factors and phorbol esters regulate Raf-1 through common mechanisms. Oncogene. 17: 1539-47. PMID 9794231 DOI: 10.1038/Sj.Onc.1202061  0.517
1998 Barnard D, Sun H, Baker L, Marshall MS. In vitro inhibition of Ras-Raf association by short peptides. Biochemical and Biophysical Research Communications. 247: 176-80. PMID 9636675 DOI: 10.1006/Bbrc.1998.8746  0.592
1998 Ge Y, Li ZH, Marshall MS, Broxmeyer HE, Lu L. Involvement of H-ras in erythroid differentiation of TF1 and human umbilical cord blood CD34 cells. Blood Cells, Molecules & Diseases. 24: 124-36; discussion 1. PMID 9628849 DOI: 10.1006/Bcmd.1998.0179  0.399
1998 Caplin BE, Ohya Y, Marshall MS. Amino acid residues that define both the isoprenoid and CAAX preferences of the Saccharomyces cerevisiae protein farnesyltransferase. Creating the perfect farnesyltransferase. The Journal of Biological Chemistry. 273: 9472-9. PMID 9545274 DOI: 10.1074/Jbc.273.16.9472  0.425
1997 O'gara MJ, Zhang Xf, Baker L, Marshall MS. Characterization of the Ras binding domain of the RalGDS-related protein, RLF. Biochemical and Biophysical Research Communications. 238: 425-9. PMID 9299525 DOI: 10.1006/Bbrc.1997.7299  0.43
1997 Diaz B, Barnard D, Filson A, MacDonald S, King A, Marshall M. Phosphorylation of Raf-1 serine 338-serine 339 is an essential regulatory event for Ras-dependent activation and biological signaling. Molecular and Cellular Biology. 17: 4509-16. PMID 9234708 DOI: 10.1128/Mcb.17.8.4509  0.505
1997 Luo Z, Diaz B, Marshall MS, Avruch J. An intact Raf zinc finger is required for optimal binding to processed Ras and for ras-dependent Raf activation in situ. Molecular and Cellular Biology. 17: 46-53. PMID 8972184 DOI: 10.1128/Mcb.17.1.46  0.406
1996 Luo Z, Tzivion G, Belshaw PJ, Vavvas D, Marshall M, Avruch J. Oligomerization activates c-Raf-1 through a Ras-dependent mechanism. Nature. 383: 181-5. PMID 8774885 DOI: 10.1038/383181A0  0.539
1996 Miao W, Eichelberger L, Baker L, Marshall MS. p120 Ras GTPase-activating protein interacts with Ras-GTP through specific conserved residues. The Journal of Biological Chemistry. 271: 15322-9. PMID 8663024 DOI: 10.1074/Jbc.271.26.15322  0.471
1996 Bryan SS, Mitchell AL, Collins F, Miao W, Marshall M, Jove R. N-terminal sequences contained in the Src homology 2 and 3 domains of p120 GTPase-activating protein are required for full catalytic activity toward Ras Journal of Biological Chemistry. 271: 5195-5199. PMID 8617802 DOI: 10.1074/Jbc.271.9.5195  0.476
1995 Marshall M. Interactions between Ras and Raf: Key regulatory proteins in cellular transformation Molecular Reproduction and Development. 42: 493-499. PMID 8607981 DOI: 10.1002/Mrd.1080420418  0.545
1995 Zhang XF, Marshall MS, Avruch J. Ras-Raf complexes in vitro. Methods in Enzymology. 255: 323-31. PMID 8524118 DOI: 10.1016/S0076-6879(95)55035-6  0.409
1995 Caplin BE, Marshall MS. Mutagenesis and biochemical analysis of recombinant yeast prenyltransferases. Methods in Enzymology. 250: 51-68. PMID 7651175 DOI: 10.1016/0076-6879(95)50062-6  0.318
1995 Marshall MS. Ras target proteins in eukaryotic cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 9: 1311-8. PMID 7557021 DOI: 10.1096/Fasebj.9.13.7557021  0.503
1995 Aronica SM, Mantel C, Gonin R, Marshall MS, Sarris A, Cooper S, Hague N, Zhang XF, Broxmeyer HE. Interferon-inducible protein 10 and macrophage inflammatory protein-1 alpha inhibit growth factor stimulation of Raf-1 kinase activity and protein synthesis in a human growth factor-dependent hematopoietic cell line. The Journal of Biological Chemistry. 270: 21998-2007. PMID 7545174 DOI: 10.1074/Jbc.270.37.21998  0.387
1995 Wang XY, Fuhrer DK, Marshall MS, Yang YC. Interleukin-11 induces complex formation of Grb2, Fyn, and JAK2 in 3T3L1 cells. The Journal of Biological Chemistry. 270: 27999-8002. PMID 7499280 DOI: 10.1074/Jbc.270.47.27999  0.425
1994 Caplin BE, Hettich LA, Marshall MS. Substrate characterization of the Saccharomyces cerevisiae protein farnesyltransferase and type-I protein geranylgeranyltransferase. Biochimica Et Biophysica Acta. 1205: 39-48. PMID 8142482 DOI: 10.1016/0167-4838(94)90089-2  0.318
1994 Chuang E, Barnard D, Hettich L, Zhang XF, Avruch J, Marshall MS. Critical binding and regulatory interactions between Ras and Raf occur through a small, stable N-terminal domain of Raf and specific Ras effector residues. Molecular and Cellular Biology. 14: 5318-25. PMID 8035810 DOI: 10.1128/Mcb.14.8.5318  0.479
1994 Tauchi T, Feng GS, Marshall MS, Shen R, Mantel C, Pawson T, Broxmeyer HE. The ubiquitously expressed Syp phosphatase interacts with c-kit and Grb2 in hematopoietic cells. The Journal of Biological Chemistry. 269: 25206-11. PMID 7523381  0.614
1993 Randall SK, Marshall MS, Crowell DN. Protein isoprenylation in suspension-cultured tobacco cells. The Plant Cell. 5: 433-42. PMID 8485402 DOI: 10.1105/Tpc.5.4.433  0.395
1993 Marshall MS, Hettich LA. Characterization of Ras effector mutant interactions with the NF1-GAP related domain. Oncogene. 8: 425-31. PMID 8426748  0.364
1993 Zhang XF, Settleman J, Kyriakis JM, Takeuchi-Suzuki E, Elledge SJ, Marshall MS, Bruder JT, Rapp UR, Avruch J. Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1. Nature. 364: 308-13. PMID 8332187 DOI: 10.1038/364308A0  0.402
1993 Marshall MS. The effector interactions of p21ras. Trends in Biochemical Sciences. 18: 250-4. PMID 8212134 DOI: 10.1016/0968-0004(93)90175-M  0.416
1992 Mayer ML, Caplin BE, Marshall MS. CDC43 and RAM2 encode the polypeptide subunits of a yeast type I protein geranylgeranyltransferase. The Journal of Biological Chemistry. 267: 20589-93. PMID 1400380  0.338
1992 Park S, Marshall MS, Gibbs JB, Jove R. Reconstitution of interactions between the Src tyrosine kinases and Ras GTPase-activating protein using a baculovirus expression system. The Journal of Biological Chemistry. 267: 11612-8. PMID 1375945  0.355
1991 Marshall MS, Davis LJ, Keys RD, Mosser SD, Hill WS, Scolnick EM, Gibbs JB. Identification of amino acid residues required for Ras p21 target activation. Molecular and Cellular Biology. 11: 3997-4004. PMID 1906576 DOI: 10.1128/Mcb.11.8.3997  0.482
1991 Farnsworth CL, Marshall MS, Gibbs JB, Stacey DW, Feig LA. Preferential inhibition of the oncogenic form of RasH by mutations in the GAP binding/"effector" domain. Cell. 64: 625-33. PMID 1899358 DOI: 10.1016/0092-8674(91)90246-U  0.477
1991 Dominguez I, Marshall MS, Gibbs JB, García de Herreros A, Cornet ME, Graziani G, Diaz-Meco MT, Johansen T, McCormick F, Moscat J. Role of GTPase activating protein in mitogenic signalling through phosphatidylcholine-hydrolysing phospholipase C. The Embo Journal. 10: 3215-20. PMID 1655413  0.416
1991 Golubić M, Tanaka K, Dobrowolski S, Wood D, Tsai M, Marshall M, Tamanoi F, Stacey D. The GTPase stimulatory activities of the neurofibromatosis type 1 and the yeast IRA2 proteins are inhibited by arachidonic acid. The Embo Journal. 10: 2897-2903. DOI: 10.1002/J.1460-2075.1991.Tb07839.X  0.468
1991 Dominguez I, Marshall M, Gibbs J, García de Herreros A, Cornet M, Graziani G, Diaz-Meco M, Johansen T, McCormick F, Moscat J. Role of GTPase activating protein in mitogenic signalling through phosphatidylcholine-hydrolysing phospholipase C. The Embo Journal. 10: 3215-3220. DOI: 10.1002/J.1460-2075.1991.Tb04884.X  0.416
1990 Schaber MD, O'Hara MB, Garsky VM, Mosser SC, Bergstrom JD, Moores SL, Marshall MS, Friedman PA, Dixon RA, Gibbs JB. Polyisoprenylation of Ras in vitro by a farnesyl-protein transferase. The Journal of Biological Chemistry. 265: 14701-4. PMID 2203759  0.361
1990 Gibbs JB, Schaber MD, Garsky VM, Vogel US, Scolnick EM, Dixon RA, Marshall MS. Structure/function relationships of ras and guanosine triphosphatase-activating protein. Society of General Physiologists Series. 45: 77-85. PMID 2198666  0.343
1990 Tanaka K, Nakafuku M, Satoh T, Marshall MS, Gibbs JB, Matsumoto K, Kaziro Y, Toh-e A. S. cerevisiae genes IRA1 and IRA2 encode proteins that may be functionally equivalent to mammalian ras GTPase activating protein. Cell. 60: 803-7. PMID 2178777 DOI: 10.1016/0092-8674(90)90094-U  0.462
1990 Gibbs JB, Marshall MS, Scolnick EM, Dixon RA, Vogel US. Modulation of guanine nucleotides bound to Ras in NIH3T3 cells by oncogenes, growth factors, and the GTPase activating protein (GAP). The Journal of Biological Chemistry. 265: 20437-42. PMID 2122974  0.428
1990 Gibbs JB, Schaber MD, Garsky VM, Vogel US, Scolnick EM, Dixon RAF, Marshall MS. Structure/function relationships of Ras and guanosine triphosphatase-activating protein Journal of General Physiology. 77-85.  0.343
1989 Gibbs JB, Marshall MS. The ras oncogene--an important regulatory element in lower eucaryotic organisms. Microbiological Reviews. 53: 171-85. PMID 2547147 DOI: 10.1128/Mmbr.53.2.171-185.1989  0.481
1989 Marshall MS, Hill WS, Ng AS, Vogel US, Schaber MD, Scolnick EM, Dixon RA, Sigal IS, Gibbs JB. A C-terminal domain of GAP is sufficient to stimulate ras p21 GTPase activity. The Embo Journal. 8: 1105-10. PMID 2545441 DOI: 10.1002/J.1460-2075.1989.Tb03480.X  0.465
1989 Schaber MD, Garsky VM, Boylan D, Hill WS, Scolnick EM, Marshall MS, Sigal IS, Gibbs JB. Ras interaction with the GTPase-activating protein (GAP). Proteins. 6: 306-15. PMID 2516318 DOI: 10.1002/Prot.340060313  0.472
1989 Molloy CJ, Bottaro DP, Fleming TP, Marshall MS, Gibbs JB, Aaronson SA. PDGF induction of tyrosine phosphorylation of GTPase activating protein. Nature. 342: 711-4. PMID 2480526 DOI: 10.1038/342711A0  0.484
1988 Marshall M, Mahoney D, Rose A, Hicks JB, Broach JR. Functional domains of SIR4, a gene required for position effect regulation in Saccharomyces cerevisiae. Molecular and Cellular Biology. 7: 4441-52. PMID 3325825 DOI: 10.1128/Mcb.7.12.4441  0.308
1988 Marshall MS, Gibbs JB, Scolnick EM, Sigal IS. An adenylate cyclase from Saccharomyces cerevisiae that is stimulated by RAS proteins with effector mutations. Molecular and Cellular Biology. 8: 52-61. PMID 3275878 DOI: 10.1128/Mcb.8.1.52  0.444
1988 Sigal IS, Marshall MS, Schaber MD, Vogel US, Scolnick EM, Gibbs JB. Structure/function studies of the ras protein. Cold Spring Harbor Symposia On Quantitative Biology. 53: 863-9. PMID 3151189 DOI: 10.1101/Sqb.1988.053.01.099  0.426
1988 Sigal IS, D'Alonzo JS, Ahern JD, Marshall MS, Smith GM, Scolnick EM, Gibbs JB. The ras oncogene protein as a G-protein. Advances in Second Messenger and Phosphoprotein Research. 21: 193-200. PMID 3137958  0.311
1988 Vogel US, Dixon RA, Schaber MD, Diehl RE, Marshall MS, Scolnick EM, Sigal IS, Gibbs JB. Cloning of bovine GAP and its interaction with oncogenic ras p21. Nature. 335: 90-3. PMID 2842690 DOI: 10.1038/335090A0  0.5
1987 Robinson LC, Gibbs JB, Marshall MS, Sigal IS, Tatchell K. CDC25: a component of the RAS-adenylate cyclase pathway in Saccharomyces cerevisiae. Science (New York, N.Y.). 235: 1218-21. PMID 3547648  0.381
1987 Marshall MS, Gibbs JB, Scolnick EM, Sigal IS. Regulatory function of the Saccharomyces cerevisiae RAS C-terminus. Molecular and Cellular Biology. 7: 2309-15. PMID 3302671 DOI: 10.1128/Mcb.7.7.2309  0.42
1987 Gibbs JB, Schaber MD, Marshall MS, Scolnick EM, Sigal IS. Identification of guanine nucleotides bound to ras-encoded proteins in growing yeast cells. The Journal of Biological Chemistry. 262: 10426-9. PMID 3038880  0.395
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