Philipp A. Lang, Ph.D. - Publications

Affiliations: 
2011 Immunology University of Toronto, Toronto, ON, Canada 
Area:
Immunology

143 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Xu HC, Pandey P, Ward H, Gorzkiewicz M, Abromavičiūtė D, Tinz C, Müller L, Meyer C, Pandyra AA, Yavas A, Borkhardt A, Esposito I, Lang KS, Lang PA. High-Affinity-Mediated Viral Entry Triggers Innate Affinity Escape Resulting in Type I IFN Resistance and Impaired T Cell Immunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 38497668 DOI: 10.4049/jimmunol.2300637  0.32
2022 Xu HC, Huang J, Pandyra AA, Pandey P, Wang R, Zhang Z, Zhuang Y, Gertzen CGW, Münk C, Herebian D, Borkhardt A, Recher M, Gohlke H, Esposito I, Oberbarnscheidt M, ... ... Lang PA, et al. Single MHC-I Expression Promotes Virus-Induced Liver Immunopathology. Hepatology Communications. PMID 35166071 DOI: 10.1002/hep4.1913  0.399
2021 Xu HC, Wang R, Shinde PV, Walotka L, Huang A, Poschmann G, Huang J, Liu W, Stühler K, Schaal H, Bergthaler A, Pandyra AA, Hardt C, Lang KS, Lang PA. Slow viral propagation during initial phase of infection leads to viral persistence in mice. Communications Biology. 4: 508. PMID 33927339 DOI: 10.1038/s42003-021-02028-x  0.387
2020 Duhan V, Khairnar V, Kitanovski S, Hamdan TA, Klein AD, Lang J, Ali M, Adomati T, Bhat H, Friedrich SK, Li F, Krebs P, Futerman AH, Addo MM, Hardt C, ... ... Lang PA, et al. Integrin Alpha E (CD103) Limits Virus-Induced IFN-I Production in Conventional Dendritic Cells. Frontiers in Immunology. 11: 607889. PMID 33584680 DOI: 10.3389/fimmu.2020.607889  0.345
2020 Bhat H, Zaun G, Hamdan TA, Lang J, Adomati T, Schmitz R, Friedrich SK, Bergerhausen M, Cham LB, Li F, Ali M, Zhou F, Khairnar V, Duhan V, Brandenburg T, ... ... Lang PA, et al. Arenavirus Induced CCL5 Expression Causes NK Cell-Mediated Melanoma Regression. Frontiers in Immunology. 11: 1849. PMID 32973762 DOI: 10.3389/Fimmu.2020.01849  0.403
2020 Al-Salihi MA, Lang PA. iRhom2: An Emerging Adaptor Regulating Immunity and Disease. International Journal of Molecular Sciences. 21. PMID 32911849 DOI: 10.3390/Ijms21186570  0.334
2020 Beyer M, Abdullah Z, Chemnitz JM, Maisel D, Sander J, Lehmann C, Thabet Y, Shinde PV, Schmidleithner L, Köhne M, Trebicka J, Schierwagen R, Hofmann A, Popov A, Lang KS, ... ... Lang PA, et al. Publisher Correction: Tumor-necrosis factor impairs CD4 T cell-mediated immunological control in chronic viral infection. Nature Immunology. PMID 32620862 DOI: 10.1038/S41590-020-0749-7  0.416
2020 Scheller J, Lang PA. Collagen-binding IL-12 inflames 'cold' tumours. Nature Biomedical Engineering. 4: 483-484. PMID 32409704 DOI: 10.1038/S41551-020-0560-7  0.348
2020 Cham LB, Torrez Dulgeroff LB, Tal MC, Adomati T, Li F, Bhat H, Huang A, Lang PA, Moreno ME, Rivera JM, Galkina SA, Kosikova G, Stoddart CA, McCune JM, Myers LM, et al. Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection. Cell Reports. 31: 107494. PMID 32294445 DOI: 10.1016/J.Celrep.2020.03.058  0.45
2020 Grutza R, Moskorz W, Senff T, Bäcker E, Lindemann M, Zimmermann A, Uhrberg M, Lang PA, Timm J, Cosmovici C. NKG2C NK Cells Regulate the Expansion of Cytomegalovirus-Specific CD8 T Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 32284334 DOI: 10.4049/Jimmunol.1901281  0.429
2020 Friedrich SK, Schmitz R, Bergerhausen M, Lang J, Cham LB, Duhan V, Häussinger D, Hardt C, Addo M, Prinz M, Asano K, Lang PA, Lang KS. Expression in CD169 Macrophages is Important for Strong Immune Response after Vaccination with VSV-EBOV. Vaccines. 8. PMID 32210083 DOI: 10.3390/Vaccines8010142  0.36
2020 Adomati T, Cham LB, Hamdan TA, Bhat H, Duhan V, Li F, Ali M, Lang E, Huang A, Naser E, Khairnar V, Friedrich SK, Lang J, Friebus-Kardash J, Bergerhausen M, ... ... Lang PA, et al. Dead Cells Induce Innate Anergy via Mertk after Acute Viral Infection. Cell Reports. 30: 3671-3681.e5. PMID 32187540 DOI: 10.1016/J.Celrep.2020.02.101  0.438
2020 Lang J, Bohn P, Bhat H, Jastrow H, Walkenfort B, Cansiz F, Fink J, Bauer M, Olszewski D, Ramos-Nascimento A, Duhan V, Friedrich SK, Becker KA, Krawczyk A, Edwards MJ, ... ... Lang PA, et al. Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease. Nature Communications. 11: 1338. PMID 32165633 DOI: 10.1038/S41467-020-15072-8  0.383
2020 Lang PA, Crome SQ, Xu HC, Lang KS, Chapatte L, Deenick EK, Grusdat M, Pandyra AA, Pozdeev VI, Wang R, Holderried TAW, Cantor H, Diefenbach A, Elford AR, McIlwain DR, et al. NK Cells Regulate CD8 T Cell Mediated Autoimmunity. Frontiers in Cellular and Infection Microbiology. 10: 36. PMID 32117809 DOI: 10.3389/Fcimb.2020.00036  0.648
2020 Hamdan TA, Lang PA, Lang KS. The Diverse Functions of the Ubiquitous Fcγ Receptors and Their Unique Constituent, FcRγ Subunit. Pathogens (Basel, Switzerland). 9. PMID 32093173 DOI: 10.3390/Pathogens9020140  0.42
2020 Hamdan TA, Bhat H, Cham LB, Adomati T, Lang J, Li F, Murtaza A, Hardt C, Lang PA, Duhan V, Lang KS. Map3k14 as a Regulator of Innate and Adaptive Immune Response during Acute Viral Infection. Pathogens (Basel, Switzerland). 9. PMID 32033109 DOI: 10.3390/Pathogens9020096  0.479
2020 Namineni S, O'Connor T, Faure-Dupuy S, Johansen P, Riedl T, Liu K, Xu H, Singh I, Shinde P, Li F, Pandyra A, Sharma P, Ringelhan M, Muschaweckh A, Borst K, ... ... Lang PA, et al. A dual role for hepatocyte-intrinsic canonical NF-κB signaling in virus control. Journal of Hepatology. PMID 31954207 DOI: 10.1016/J.Jhep.2019.12.019  0.399
2019 Sundaram B, Behnke K, Belancic A, Al-Salihi MA, Thabet Y, Polz R, Pellegrino R, Zhuang Y, Shinde PV, Xu HC, Vasilevska J, Longerich T, Herebian D, Mayatepek E, Bock HH, ... ... Lang PA, et al. iRhom2 inhibits bile duct obstruction-induced liver fibrosis. Science Signaling. 12. PMID 31662486 DOI: 10.1126/Scisignal.Aax1194  0.334
2019 Zhang E, Ma Z, Li Q, Yan H, Liu J, Wu W, Guo J, Zhang X, Kirschning CJ, Xu H, Lang PA, Yang D, Dittmer U, Yan H, Lu M. TLR2 Stimulation Increases Cellular Metabolism in CD8 T Cells and Thereby Enhances CD8 T Cell Activation, Function, and Antiviral Activity. Journal of Immunology (Baltimore, Md. : 1950). PMID 31636238 DOI: 10.4049/Jimmunol.1900065  0.465
2019 Li Q, Yan Y, Liu J, Huang X, Zhang X, Kirschning C, Xu HC, Lang PA, Dittmer U, Zhang E, Lu M. Toll-Like Receptor 7 Activation Enhances CD8+ T Cell Effector Functions by Promoting Cellular Glycolysis. Frontiers in Immunology. 10: 2191. PMID 31572396 DOI: 10.3389/Fimmu.2019.02191  0.458
2019 Huang A, Shinde PV, Huang J, Senff T, Xu HC, Margotta C, Häussinger D, Willnow TE, Zhang J, Pandyra AA, Timm J, Weggen S, Lang KS, Lang PA. Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells. Jci Insight. 4. PMID 31484831 DOI: 10.1172/Jci.Insight.129856  0.52
2019 Duhan V, Hamdan TA, Xu HC, Shinde P, Bhat H, Li F, Al-Matary Y, Häussinger D, Bezgovsek J, Friedrich SK, Hardt C, Lang PA, Lang KS. NK cell-intrinsic FcεRIγ limits CD8+ T-cell expansion and thereby turns an acute into a chronic viral infection. Plos Pathogens. 15: e1007797. PMID 31220194 DOI: 10.1371/Journal.Ppat.1007797  0.495
2019 Baazim H, Schweiger M, Moschinger M, Xu H, Scherer T, Popa A, Gallage S, Ali A, Khamina K, Kosack L, Vilagos B, Smyth M, Lercher A, Friske J, Merkler D, ... ... Lang PA, et al. CD8 T cells induce cachexia during chronic viral infection. Nature Immunology. PMID 31110314 DOI: 10.1038/S41590-019-0397-Y  0.486
2019 Behnke K, Zhuang Y, Xu HC, Sundaram B, Reich M, Shinde PV, Huang J, Modares NF, Tumanov AV, Polz R, Scheller J, Ware CF, Pfeffer K, Keitel V, Häussinger D, ... ... Lang PA, et al. Response to: Characterization of CD169+ macrophages in liver regeneration: tissue distribution and fate? Hepatology (Baltimore, Md.). PMID 30829412 DOI: 10.1002/Hep.30600  0.339
2019 Lang PA, Lang KS. Stand by me(mory): Chronic infection diminishes memory pool via IL-6/STAT1. The Journal of Experimental Medicine. PMID 30782615 DOI: 10.1084/Jem.20190066  0.396
2019 Reich M, Deutschmann K, Stindt J, Xu HC, Lang P, Häussinger D, Keitel V. PS-040-Bacterial infection upregulates TGR5 expression in a Krüppel-like-factor 5-dependent manner Journal of Hepatology. 70. DOI: 10.1016/S0618-8278(19)30046-5  0.309
2018 Lang E, Pozdeev VI, Shinde PV, Xu HC, Sundaram B, Zhuang Y, Poschmann G, Huang J, Stühler K, Pandyra AA, Keitel V, Häussinger D, Lang KS, Lang PA. Cholestasis induced liver pathology results in dysfunctional immune responses after arenavirus infection. Scientific Reports. 8: 12179. PMID 30111770 DOI: 10.1038/S41598-018-30627-Y  0.514
2018 Osei Kuffour E, Schott K, Jaguva Vasudevan AA, Holler J, Schulz WA, Lang PA, Lang KS, Kim B, Häussinger D, König R, Münk C. USP18 (UBP43) Abrogates p21-Mediated Inhibition of HIV-1. Journal of Virology. PMID 30068654 DOI: 10.1128/Jvi.00592-18  0.361
2018 Probst K, Stermann J, von Bomhard I, Etich J, Pitzler L, Niehoff A, Bluhm B, Xu HC, Lang PA, Chmielewski M, Abken H, Blissenbach B, Machova A, Papadopoulou N, Brachvogel B. Depletion of collagen IX alpha1 impairs myeloid cell function. Stem Cells (Dayton, Ohio). PMID 30063808 DOI: 10.1002/Stem.2892  0.372
2018 Urbahn MA, Kaup SC, Reusswig F, Krüger I, Spelleken M, Jurk K, Klier M, Lang PA, Elvers M. Phospholipase D1 regulation of TNF-alpha protects against responses to LPS. Scientific Reports. 8: 10006. PMID 29968773 DOI: 10.1038/S41598-018-28331-Y  0.322
2018 Khairnar V, Duhan V, Patil AM, Zhou F, Bhat H, Thoens C, Sharma P, Adomati T, Friendrich SK, Bezgovsek J, Dreesen JD, Wennemuth G, Westendorf AM, Zelinskyy G, Dittmer U, ... ... Lang PA, et al. CEACAM1 promotes CD8 T cell responses and improves control of a chronic viral infection. Nature Communications. 9: 2561. PMID 29967450 DOI: 10.1038/S41467-018-04832-2  0.483
2018 Behnke K, Zhuang Y, Xu HC, Sundaram B, Reich M, Shinde PV, Huang J, Modares NF, Tumanov AV, Polz R, Scheller J, Ware CF, Pfeffer K, Keitel V, Häussinger D, ... ... Lang PA, et al. B cell-mediated maintenance of CD169 cells is critical for liver regeneration. Hepatology (Baltimore, Md.). PMID 29742809 DOI: 10.1002/Hep.30088  0.383
2017 Xu HC, Huang J, Pandyra AA, Lang E, Zhuang Y, Thöns C, Timm J, Häussinger D, Colonna M, Cantor H, Lang KS, Lang PA. Lymphocytes Negatively Regulate NK Cell Activity via Qa-1b following Viral Infection. Cell Reports. 21: 2528-2540. PMID 29186689 DOI: 10.1016/J.Celrep.2017.11.001  0.524
2017 Shinde PV, Xu HC, Maney SK, Kloetgen A, Namineni S, Zhuang Y, Honke N, Shaabani N, Bellora N, Doerrenberg M, Trilling M, Pozdeev VI, van Rooijen N, Scheu S, Pfeffer K, ... ... Lang PA, et al. TNF-mediated survival of CD169(+) cells promotes immune activation during vesicular stomatitis virus infection. Journal of Virology. PMID 29142134 DOI: 10.1128/Jvi.01637-17  0.479
2017 Huber M, Suprunenko T, Ashhurst T, Marbach F, Raifer H, Wolff S, Strecker T, Viengkhou B, Jung SR, Obermann HL, Bauer S, Xu HC, Lang P, Tom A, Lang KS, et al. IRF9 prevents CD8(+) T cell exhaustion in an extrinsic manner during acute LCMV infection. Journal of Virology. PMID 28878077 DOI: 10.1128/Jvi.01219-17  0.502
2017 Pozdeev VI, Lang E, Görg B, Bidmon HJ, Shinde PV, Kircheis G, Herebian D, Pfeffer K, Lang F, Häussinger D, Lang KS, Lang PA. TNFα induced up-regulation of Na(+),K(+),2Cl(-) cotransporter NKCC1 in hepatic ammonia clearance and cerebral ammonia toxicity. Scientific Reports. 7: 7938. PMID 28801579 DOI: 10.1038/S41598-017-07640-8  0.318
2017 Delacher M, Imbusch CD, Weichenhan D, Breiling A, Hotz-Wagenblatt A, Träger U, Hofer AC, Kägebein D, Wang Q, Frauhammer F, Mallm JP, Bauer K, Herrmann C, Lang PA, Brors B, et al. Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues. Nature Immunology. PMID 28783152 DOI: 10.1038/Ni.3799  0.369
2017 Sharma P, Khairnar V, Madunić IV, Singh Y, Pandyra A, Salker MS, Koepsell H, Sabolić I, Lang F, Lang PA, Lang KS. SGLT1 Deficiency Turns Listeria Infection into a Lethal Disease in Mice. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 42: 1358-1365. PMID 28704812 DOI: 10.1159/000479197  0.34
2017 Mak TW, Grusdat M, Duncan GS, Dostert C, Nonnenmacher Y, Cox M, Binsfeld C, Hao Z, Brüstle A, Itsumi M, Jäger C, Chen Y, Pinkenburg O, Camara B, Ollert M, ... ... Lang PA, et al. Glutathione Primes T Cell Metabolism for Inflammation. Immunity. 46: 675-689. PMID 28423341 DOI: 10.1016/J.Immuni.2017.03.019  0.425
2017 Kalkavan H, Sharma P, Kasper S, Helfrich I, Pandyra AA, Gassa A, Virchow I, Flatz L, Brandenburg T, Namineni S, Heikenwalder M, Höchst B, Knolle PA, Wollmann G, von Laer D, ... ... Lang PA, et al. Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression. Nature Communications. 8: 14447. PMID 28248314 DOI: 10.1038/Ncomms14447  0.422
2017 Honke N, Shaabani N, Teijaro JR, Christen U, Hardt C, Bezgovsek J, Lang PA, Lang KS. Presentation of Autoantigen in Peripheral Lymph Nodes Is Sufficient for Priming Autoreactive CD8(+) T Cells. Frontiers in Immunology. 8: 113. PMID 28239381 DOI: 10.3389/Fimmu.2017.00113  0.436
2017 Honke N, Shaabani N, Hardt C, Krings C, Häussinger D, Lang PA, Lang KS, Keitel V. Farnesoid X Receptor in Mice Prevents Severe Liver Immunopathology During Lymphocytic Choriomeningitis Virus Infection. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 41: 323-338. PMID 28214859 DOI: 10.1159/000456168  0.343
2017 Crome SQ, Nguyen LT, Lopez-Verges S, Yang SY, Martin B, Yam JY, Johnson DJ, Nie J, Pniak M, Yen PH, Milea A, Sowamber R, Katz SR, Bernardini MQ, Clarke BA, ... ... Lang PA, et al. A distinct innate lymphoid cell population regulates tumor-associated T cells. Nature Medicine. PMID 28165478 DOI: 10.1038/Nm.4278  0.601
2016 Wu T, Ji Y, Moseman EA, Xu HC, Manglani M, Kirby M, Anderson SM, Handon R, Kenyon E, Elkahloun A, Wu W, Lang PA, Gattinoni L, McGavern DB, Schwartzberg PL. The TCF1-Bcl6 axis counteracts type I interferon to repress exhaustion and maintain T cell stemness. Science Immunology. 1. PMID 28018990 DOI: 10.1126/Sciimmunol.Aai8593  0.486
2016 Shaabani N, Duhan V, Khairnar V, Gassa A, Ferrer-Tur R, Häussinger D, Recher M, Zelinskyy G, Liu J, Dittmer U, Trilling M, Scheu S, Hardt C, Lang PA, Honke N, et al. CD169(+) macrophages regulate PD-L1 expression via type I interferon and thereby prevent severe immunopathology after LCMV infection. Cell Death & Disease. 7: e2446. PMID 27809306 DOI: 10.1038/Cddis.2016.350  0.427
2016 Gil-Cruz C, Perez-Shibayama C, Onder L, Chai Q, Cupovic J, Cheng HW, Novkovic M, Lang PA, Geuking MB, McCoy KD, Abe S, Cui G, Ikuta K, Scandella E, Ludewig B. Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs. Nature Immunology. PMID 27798617 DOI: 10.1038/Ni.3566  0.398
2016 Maney SK, Xu HC, Huang J, Pandyra AA, Ehlting C, Aguilar-Valenzuela R, Pozdeev VI, McIlwain DR, Zimmermann A, Bode JG, Hengel H, Kirschning CJ, Kim IR, Hiscott J, Brenner D, ... ... Lang PA, et al. RAIDD Mediates TLR3 and IRF7 Driven Type I Interferon Production. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 39: 1271-1280. PMID 27606466 DOI: 10.1159/000447832  0.688
2016 Bhavsar SK, Singh Y, Sharma P, Khairnar V, Hosseinzadeh Z, Zhang S, Palmada M, Sabolic I, Koepsell H, Lang KS, Lang PA, Lang F. Expression of JAK3 Sensitive Na+ Coupled Glucose Carrier SGLT1 in Activated Cytotoxic T Lymphocytes. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 39: 1209-28. PMID 27595398 DOI: 10.1159/000447827  0.307
2016 Lang E, Pozdeev VI, Xu HC, Shinde PV, Behnke K, Hamdam JM, Lehnert E, Scharf RE, Lang F, Häussinger D, Lang KS, Lang PA. Storage of Erythrocytes Induces Suicidal Erythrocyte Death. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 39: 668-676. PMID 27442519 DOI: 10.1159/000445657  0.344
2016 Lang E, Pozdeev VI, Gatidis S, Qadri SM, Häussinger D, Kubitz R, Herebian D, Mayatepek E, Lang F, Lang KS, Lang PA. Bile Acid-Induced Suicidal Erythrocyte Death. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 38: 1500-1509. PMID 27050423 DOI: 10.1159/000443091  0.328
2016 Gassa A, Kalkavan H, Jian F, Duhan V, Khairnar V, Shaabani N, Honke N, Carpinteiro A, Botezatu L, Crivello P, Dolff S, Ferencik S, Häussinger D, Khandanpour C, Fleischhauer K, ... ... Lang PA, et al. High Frequencies of Anti-Host Reactive CD8+ T Cells Ignore Non-Hematopoietic Antigen after Bone Marrow Transplantation in a Murine Model. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 38: 1343-1353. PMID 27007114 DOI: 10.1159/000443078  0.447
2016 Gassa A, Jian F, Kalkavan H, Duhan V, Honke N, Shaabani N, Friedrich SK, Dolff S, Wahlers T, Kribben A, Hardt C, Lang PA, Witzke O, Lang KS. IL-10 Induces T Cell Exhaustion During Transplantation of Virus Infected Hearts. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 38: 1171-1181. PMID 26963287 DOI: 10.1159/000443067  0.434
2016 Beyer M, Abdullah Z, Chemnitz JM, Maisel D, Sander J, Lehmann C, Thabet Y, Shinde PV, Schmidleithner L, Köhne M, Trebicka J, Schierwagen R, Hofmann A, Popov A, Lang KS, ... ... Lang PA, et al. Tumor-necrosis factor impairs CD4(+) T cell-mediated immunological control in chronic viral infection. Nature Immunology. PMID 26950238 DOI: 10.1038/Ni.3399  0.491
2016 Duhan V, Khairnar V, Friedrich SK, Zhou F, Gassa A, Honke N, Shaabani N, Gailus N, Botezatu L, Khandanpour C, Dittmer U, Häussinger D, Recher M, Hardt C, Lang PA, et al. Virus-specific antibodies allow viral replication in the marginal zone, thereby promoting CD8(+) T-cell priming and viral control. Scientific Reports. 6: 19191. PMID 26805453 DOI: 10.1038/Srep19191  0.448
2015 Bhattacharya A, Hegazy AN, Deigendesch N, Kosack L, Cupovic J, Kandasamy RK, Hildebrandt A, Merkler D, Kühl AA, Vilagos B, Schliehe C, Panse I, Khamina K, Baazim H, Arnold I, ... ... Lang PA, et al. Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage. Immunity. 43: 974-86. PMID 26588782 DOI: 10.1016/J.Immuni.2015.10.013  0.397
2015 Shaabani N, Khairnar V, Duhan V, Zhou F, Tur RF, Häussinger D, Recher M, Tumanov AV, Hardt C, Pinschewer D, Christen U, Lang PA, Honke N, Lang KS. Two separate mechanisms of enforced viral replication balance innate and adaptive immune activation. Journal of Autoimmunity. PMID 26553386 DOI: 10.1016/J.Jaut.2015.10.004  0.446
2015 Maney SK, McIlwain DR, Polz R, Pandyra AA, Sundaram B, Wolff D, Ohishi K, Maretzky T, Brooke MA, Evers A, Vasudevan AA, Aghaeepour N, Scheller J, Münk C, Häussinger D, ... ... Lang PA, et al. Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17. Science Signaling. 8: ra109. PMID 26535007 DOI: 10.1126/Scisignal.Aac5356  0.376
2015 Honke N, Shaabani N, Merches K, Gassa A, Kraft A, Ehrhardt K, Häussinger D, Löhning M, Dittmer U, Hengel H, Recher M, Lang PA, Lang KS. Immunoactivation induced by chronic viral infection inhibits viral replication and drives immunosuppression through sustained IFN-I responses. European Journal of Immunology. PMID 26507703 DOI: 10.1002/Eji.201545765  0.484
2015 Merches K, Khairnar V, Knuschke T, Shaabani N, Honke N, Duhan V, Recher M, Navarini AA, Hardt C, Häussinger D, Tümmler B, Gulbins E, Futerman AH, Hoffmann D, Lang F, ... Lang PA, et al. Virus-Induced Type I Interferon Deteriorates Control of Systemic Pseudomonas Aeruginosa Infection. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 36: 2379-92. PMID 26279441 DOI: 10.1159/000430200  0.384
2015 Shaabani N, Honke N, Dolff S, Görg B, Khairnar V, Merches K, Duhan V, Metzger S, Recher M, Barthuber C, Hardt C, Proksch P, Häussinger D, Witzke O, Lang PA, et al. IFN-γ licenses CD11b(+) cells to induce progression of systemic lupus erythematosus. Journal of Autoimmunity. 62: 11-21. PMID 26094774 DOI: 10.1016/J.Jaut.2015.05.007  0.446
2015 Itsumi M, Inoue S, Elia AJ, Murakami K, Sasaki M, Lind EF, Brenner D, Harris IS, Chio II, Afzal S, Cairns RA, Cescon DW, Elford AR, Ye J, Lang PA, et al. Idh1 protects murine hepatocytes from endotoxin-induced oxidative stress by regulating the intracellular NADP(+)/NADPH ratio. Cell Death and Differentiation. PMID 25882048 DOI: 10.1038/Cdd.2015.38  0.522
2015 Khairnar V, Duhan V, Maney SK, Honke N, Shaabani N, Pandyra AA, Seifert M, Pozdeev V, Xu HC, Sharma P, Baldin F, Marquardsen F, Merches K, Lang E, Kirschning C, ... ... Lang PA, et al. CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production. Nature Communications. 6: 6217. PMID 25692415 DOI: 10.1038/Ncomms7217  0.355
2015 Xu HC, Huang J, Khairnar V, Duhan V, Pandyra AA, Grusdat M, Shinde P, McIlwain DR, Maney SK, Gommerman J, Löhning M, Ohashi PS, Mak TW, Pieper K, Sic H, ... ... Lang PA, et al. Deficiency of the B cell-activating factor receptor results in limited CD169+ macrophage function during viral infection. Journal of Virology. 89: 4748-59. PMID 25673724 DOI: 10.1128/Jvi.02976-14  0.651
2015 Rahbar R, Lin A, Ghazarian M, Yau HL, Paramathas S, Lang PA, Schildknecht A, Elford AR, Garcia-Batres C, Martin B, Berman HK, Leong WL, McCready DR, Reedijk M, Done SJ, et al. B7-H4 expression by nonhematopoietic cells in the tumor microenvironment promotes antitumor immunity. Cancer Immunology Research. 3: 184-95. PMID 25527357 DOI: 10.1158/2326-6066.Cir-14-0113  0.524
2015 Crouse J, Xu HC, Lang PA, Oxenius A. NK cells regulating T cell responses: mechanisms and outcome. Trends in Immunology. 36: 49-58. PMID 25432489 DOI: 10.1016/J.It.2014.11.001  0.473
2015 McIlwain DR, Grusdat M, Pozdeev VI, Xu HC, Shinde P, Reardon C, Hao Z, Beyer M, Bergthaler A, Häussinger D, Nolan GP, Lang KS, Lang PA. T-cell STAT3 is required for the maintenance of humoral immunity to LCMV. European Journal of Immunology. 45: 418-27. PMID 25393615 DOI: 10.1002/Eji.201445060  0.529
2015 Lang PA, Meryk A, Pandyra AA, Brenner D, Brüstle A, Xu HC, Merches K, Lang F, Khairnar V, Sharma P, Funkner P, Recher M, Shaabani N, Duncan GS, Duhan V, et al. Toso regulates differentiation and activation of inflammatory dendritic cells during persistence-prone virus infection. Cell Death and Differentiation. 22: 164-73. PMID 25257173 DOI: 10.1038/Cdd.2014.138  0.628
2015 Lang E, Gatidis S, Freise NF, Bock H, Kubitz R, Lauermann C, Orth HM, Klindt C, Schuier M, Keitel V, Reich M, Liu G, Schmidt S, Xu HC, Qadri SM, ... ... Lang PA, et al. Conjugated bilirubin triggers anemia by inducing erythrocyte death. Hepatology (Baltimore, Md.). 61: 275-84. PMID 25065608 DOI: 10.1002/Hep.27338  0.318
2014 Joedicke JJ, Myers L, Carmody AB, Messer RJ, Wajant H, Lang KS, Lang PA, Mak TW, Hasenkrug KJ, Dittmer U. Activated CD8+ T cells induce expansion of Vβ5+ regulatory T cells via TNFR2 signaling. Journal of Immunology (Baltimore, Md. : 1950). 193: 2952-60. PMID 25098294 DOI: 10.4049/Jimmunol.1400649  0.455
2014 Parish IA, Marshall HD, Staron MM, Lang PA, Brüstle A, Chen JH, Cui W, Tsui YC, Perry C, Laidlaw BJ, Ohashi PS, Weaver CT, Kaech SM. Chronic viral infection promotes sustained Th1-derived immunoregulatory IL-10 via BLIMP-1. The Journal of Clinical Investigation. 124: 3455-68. PMID 25003188 DOI: 10.1172/Jci66108  0.582
2014 Xu HC, Grusdat M, Pandyra AA, Polz R, Huang J, Sharma P, Deenen R, Köhrer K, Rahbar R, Diefenbach A, Gibbert K, Löhning M, Höcker L, Waibler Z, Häussinger D, ... ... Lang PA, et al. Type I interferon protects antiviral CD8+ T cells from NK cell cytotoxicity. Immunity. 40: 949-60. PMID 24909887 DOI: 10.1016/J.Immuni.2014.05.004  0.644
2014 Grusdat M, McIlwain DR, Xu HC, Pozdeev VI, Knievel J, Crome SQ, Robert-Tissot C, Dress RJ, Pandyra AA, Speiser DE, Lang E, Maney SK, Elford AR, Hamilton SR, Scheu S, ... ... Lang PA, et al. IRF4 and BATF are critical for CD8⁺ T-cell function following infection with LCMV. Cell Death and Differentiation. 21: 1050-60. PMID 24531538 DOI: 10.1038/Cdd.2014.19  0.645
2014 Brenner D, Brüstle A, Lin GH, Lang PA, Duncan GS, Knobbe-Thomsen CB, St Paul M, Reardon C, Tusche MW, Snow B, Hamilton SR, Pfefferle A, Gilani SO, Ohashi PS, Lang KS, et al. Toso controls encephalitogenic immune responses by dendritic cells and regulatory T cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 1060-5. PMID 24398517 DOI: 10.1073/Pnas.1323166111  0.615
2014 Lang KS, Honke N, Shaabani N, Häussinger D, Lang PA. Enforced viral replication, a mechanism for immune activation European Journal of Medical Research. 19: 1-2. DOI: 10.1186/2047-783X-19-S1-S26  0.49
2014 Lang P, Häussinger D, Lang KS. Immune functions during chronic viral infections European Journal of Medical Research. 19: 1-1. DOI: 10.1186/2047-783X-19-S1-S25  0.519
2013 Holderried TA, Lang PA, Kim HJ, Cantor H. Genetic disruption of CD8+ Treg activity enhances the immune response to viral infection. Proceedings of the National Academy of Sciences of the United States of America. 110: 21089-94. PMID 24324159 DOI: 10.1073/Pnas.1320999110  0.493
2013 Honke N, Shaabani N, Zhang DE, Iliakis G, Xu HC, Häussinger D, Recher M, Löhning M, Lang PA, Lang KS. Usp18 driven enforced viral replication in dendritic cells contributes to break of immunological tolerance in autoimmune diabetes. Plos Pathogens. 9: e1003650. PMID 24204252 DOI: 10.1371/Journal.Ppat.1003650  0.467
2013 Lang KS, Lang PA, Meryk A, Pandyra AA, Merches K, Lee KH, Mak TW. Reply to Honjo et al.: Functional relevant expression of Toso on granulocytes. Proceedings of the National Academy of Sciences of the United States of America. 110: E2542-3. PMID 24003457 DOI: 10.1073/Pnas.1306422110  0.361
2013 Raczkowski F, Ritter J, Heesch K, Schumacher V, Guralnik A, Höcker L, Raifer H, Klein M, Bopp T, Harb H, Kesper DA, Pfefferle PI, Grusdat M, Lang PA, Mittrücker HW, et al. The transcription factor interferon regulatory factor 4 is required for the generation of protective effector CD8+ T cells Proceedings of the National Academy of Sciences of the United States of America. 110: 15019-15024. PMID 23980171 DOI: 10.1073/Pnas.1309378110  0.462
2013 Crome SQ, Lang PA, Lang KS, Ohashi PS. Natural killer cells regulate diverse T cell responses. Trends in Immunology. 34: 342-9. PMID 23601842 DOI: 10.1016/J.It.2013.03.002  0.63
2013 Lang KS, Lang PA, Meryk A, Pandyra AA, Boucher LM, Pozdeev VI, Tusche MW, Göthert JR, Haight J, Wakeham A, You-Ten AJ, McIlwain DR, Merches K, Khairnar V, Recher M, et al. Involvement of Toso in activation of monocytes, macrophages, and granulocytes. Proceedings of the National Academy of Sciences of the United States of America. 110: 2593-8. PMID 23359703 DOI: 10.1073/Pnas.1222264110  0.592
2013 Issuree PD, Maretzky T, McIlwain DR, Monette S, Qing X, Lang PA, Swendeman SL, Park-Min KH, Binder N, Kalliolias GD, Yarilina A, Horiuchi K, Ivashkiv LB, Mak TW, Salmon JE, et al. iRHOM2 is a critical pathogenic mediator of inflammatory arthritis. The Journal of Clinical Investigation. 123: 928-32. PMID 23348744 DOI: 10.1172/Jci66168  0.387
2013 Lang PA, Xu HC, Grusdat M, McIlwain DR, Pandyra AA, Harris IS, Shaabani N, Honke N, Maney SK, Lang E, Pozdeev VI, Recher M, Odermatt B, Brenner D, Häussinger D, et al. Reactive oxygen species delay control of lymphocytic choriomeningitis virus. Cell Death and Differentiation. 20: 649-58. PMID 23328631 DOI: 10.1038/Cdd.2012.167  0.636
2013 Lang PA, Shaabani N, Borkens S, Honke N, Scheu S, Booth S, Brenner D, Meryk A, Barthuber C, Recher M, Mak TW, Ohashi PS, Häussinger D, Griffiths GM, Thrasher AJ, et al. Reduced type I interferon production by dendritic cells and weakened antiviral immunity in patients with Wiskott-Aldrich syndrome protein deficiency. The Journal of Allergy and Clinical Immunology. 131: 815-24. PMID 23141740 DOI: 10.1016/J.Jaci.2012.08.050  0.58
2013 Holderried TA, Kim H, Lang PA, Cantor H. CD8+ Treg - From Mouse To Man Blood. 122: 3474-3474. DOI: 10.1182/Blood.V122.21.3474.3474  0.389
2013 Holderried TA, Kim H, Lang PA, Cantor H. Releasing CD8+ Treg Mediated Suppresssion Enhances Anti-Viral Immune Response Blood. 122: 2280-2280. DOI: 10.1182/Blood.V122.21.2280.2280  0.461
2012 Brüstle A, Brenner D, Knobbe CB, Lang PA, Virtanen C, Hershenfield BM, Reardon C, Lacher SM, Ruland J, Ohashi PS, Mak TW. The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells. The Journal of Clinical Investigation. 122: 4698-709. PMID 23114599 DOI: 10.1172/JCI63528  0.523
2012 Chen G, Dimitriou I, Milne L, Lang KS, Lang PA, Fine N, Ohashi PS, Kubes P, Rottapel R. The 3BP2 adapter protein is required for chemoattractant-mediated neutrophil activation. Journal of Immunology (Baltimore, Md. : 1950). 189: 2138-50. PMID 22815290 DOI: 10.4049/Jimmunol.1103184  0.535
2012 Kaesler S, Sobiesiak M, Kneilling M, Volz T, Kempf WE, Lang PA, Lang KS, Wieder T, Heller-Stilb B, Warskulat U, Häussinger D, Lang F, Biedermann T. Effective T-cell recall responses require the taurine transporter Taut. European Journal of Immunology. 42: 831-41. PMID 22531910 DOI: 10.1002/Eji.201141690  0.475
2012 Recher M, Burns SO, de la Fuente MA, Volpi S, Dahlberg C, Walter JE, Moffitt K, Mathew D, Honke N, Lang PA, Patrizi L, Falet H, Keszei M, Mizui M, Csizmadia E, et al. B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice. Blood. 119: 2819-28. PMID 22302739 DOI: 10.1182/Blood-2011-09-379412  0.396
2012 McIlwain DR, Lang PA, Maretzky T, Hamada K, Ohishi K, Maney SK, Berger T, Murthy A, Duncan G, Xu HC, Lang KS, Häussinger D, Wakeham A, Itie-Youten A, Khokha R, et al. iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS. Science (New York, N.Y.). 335: 229-32. PMID 22246778 DOI: 10.1126/Science.1214448  0.553
2012 Hao Z, Duncan GS, Su YW, Li WY, Silvester J, Hong C, You H, Brenner D, Gorrini C, Haight J, Wakeham A, You-Ten A, McCracken S, Elia A, Li Q, ... ... Lang PA, et al. The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis. The Journal of Experimental Medicine. 209: 173-86. PMID 22213803 DOI: 10.1084/Jem.20111363  0.55
2012 Wang C, McPherson AJ, Jones RB, Kawamura KS, Lin GH, Lang PA, Ambagala T, Pellegrini M, Calzascia T, Aidarus N, Elford AR, Yue FY, Kremmer E, Kovacs CM, Benko E, et al. Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infection. The Journal of Experimental Medicine. 209: 77-91. PMID 22184633 DOI: 10.1084/Jem.20110675  0.572
2012 Lang PA, Lang KS, Xu HC, Grusdat M, Parish IA, Recher M, Elford AR, Dhanji S, Shaabani N, Tran CW, Dissanayake D, Rahbar R, Ghazarian M, Brüstle A, Fine J, et al. Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity. Proceedings of the National Academy of Sciences of the United States of America. 109: 1210-5. PMID 22167808 DOI: 10.1073/Pnas.1118834109  0.799
2012 Honke N, Shaabani N, Cadeddu G, Sorg UR, Zhang DE, Trilling M, Klingel K, Sauter M, Kandolf R, Gailus N, van Rooijen N, Burkart C, Baldus SE, Grusdat M, Löhning M, ... ... Lang PA, et al. Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus. Nature Immunology. 13: 51-7. PMID 22101728 DOI: 10.1038/Ni.2169  0.438
2011 Nguyen XH, Lang PA, Lang KS, Adam D, Fattakhova G, Föger N, Kamal MA, Prilla P, Mathieu S, Wagner C, Mak T, Chan AC, Lee KH. Toso regulates the balance between apoptotic and nonapoptotic death receptor signaling by facilitating RIP1 ubiquitination. Blood. 118: 598-608. PMID 21613257 DOI: 10.1182/Blood-2010-10-313643  0.371
2011 Pellegrini M, Calzascia T, Toe JG, Preston SP, Lin AE, Elford AR, Shahinian A, Lang PA, Lang KS, Morre M, Assouline B, Lahl K, Sparwasser T, Tedder TF, Paik JH, et al. IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology. Cell. 144: 601-13. PMID 21295337 DOI: 10.1016/J.Cell.2011.01.011  0.574
2011 Su YW, Hao Z, Hirao A, Yamamoto K, Lin WJ, Young A, Duncan GS, Yoshida H, Wakeham A, Lang PA, Murakami K, Hermeking H, Vogelstein B, Ohashi P, Mak TW. 14-3-3sigma regulates B-cell homeostasis through stabilization of FOXO1. Proceedings of the National Academy of Sciences of the United States of America. 108: 1555-60. PMID 21205887 DOI: 10.1073/Pnas.1017729108  0.558
2011 Su YW, Hao Z, Hirao A, Yamamoto K, Lin WJ, Young A, Duncan GS, Yoshida H, Wakeham A, Lang PA, Murakami K, Hermeking H, Vogelstein B, Ohashi P, Mak TW. 14-3-3σ regulates B-cell homeostasis through stabilization of FOXO1 (Proceedings of the National Academy of Sciences of the United States of America (2011) 108, 4, (1555-1560) DOI: 10.1073/pnas.1017729108) Proceedings of the National Academy of Sciences of the United States of America. 108: 6689. DOI: 10.1073/Pnas.1104407108  0.424
2011 Rahbar R, Lin A, Ghazarian M, Lang P, Elford AR, Suh W, Mak TW, Ohashi PS. PS2-085 Understanding anti-tumor immunity in breast cancer: Characterization the influence of B7-H4 in T cell responses to tumor antigens Cytokine. 56: 86-87. DOI: 10.1016/J.Cyto.2011.07.248  0.525
2010 Lang PA, Recher M, Häussinger D, Lang KS. Genes determining the course of virus persistence in the liver: lessons from murine infection with lymphocytic choriomeningitis virus. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 26: 263-72. PMID 20798510 DOI: 10.1159/000320549  0.435
2010 Lang PA, Merkler D, Funkner P, Shaabani N, Meryk A, Krings C, Barthuber C, Recher M, Brück W, Häussinger D, Ohashi PS, Lang KS. Oxidized ATP inhibits T-cell-mediated autoimmunity. European Journal of Immunology. 40: 2401-8. PMID 20683833 DOI: 10.1002/Eji.200939838  0.6
2010 Lang PA, Recher M, Honke N, Scheu S, Borkens S, Gailus N, Krings C, Meryk A, Kulawik A, Cervantes-Barragan L, Van Rooijen N, Kalinke U, Ludewig B, Hengartner H, Harris N, et al. Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice. Hepatology (Baltimore, Md.). 52: 25-32. PMID 20578253 DOI: 10.1002/Hep.23640  0.618
2010 Walter JE, Rucci F, Patrizi L, Recher M, Regenass S, Paganini T, Keszei M, Pessach I, Lang PA, Poliani PL, Giliani S, Al-Herz W, Cowan MJ, Puck JM, Bleesing J, et al. Expansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunodeficiency. The Journal of Experimental Medicine. 207: 1541-54. PMID 20547827 DOI: 10.1084/Jem.20091927  0.412
2010 Lang F, Gulbins E, Lang PA, Zappulla D, Föller M. Ceramide in suicidal death of erythrocytes. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 26: 21-8. PMID 20502001 DOI: 10.1159/000315102  0.354
2010 Lang E, Lang PA, Shumilina E, Qadri SM, Kucherenko Y, Kempe DS, Föller M, Capasso A, Wieder T, Gulbins E, Clemen CS, Herr C, Noegel AA, Huber SM, Lang F. Enhanced eryptosis of erythrocytes from gene-targeted mice lacking annexin A7. Pflã¼Gers Archiv : European Journal of Physiology. 460: 667-76. PMID 20490540 DOI: 10.1007/S00424-010-0829-X  0.324
2009 Lang PA, Kasinathan RS, Brand VB, Duranton C, Lang C, Koka S, Shumilina E, Kempe DS, Tanneur V, Akel A, Lang KS, Foller M, Kun JF, Kremsner PG, Wesselborg S, et al. Accelerated clearance of Plasmodium-infected erythrocytes in sickle cell trait and annexin-A7 deficiency. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 24: 415-28. PMID 19910682 DOI: 10.1159/000257529  0.317
2009 Lupescu A, Geiger C, Zahir N, Aberle S, Lang PA, Kramer S, Wesselborg S, Kandolf R, Foller M, Lang F, Bock CT. Inhibition of Na+/H+ exchanger activity by parvovirus B19 protein NS1. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 23: 211-20. PMID 19255516 DOI: 10.1159/000204110  0.306
2009 Lang PA, Cervantes-Barragan L, Verschoor A, Navarini AA, Recher M, Pellegrini M, Flatz L, Bergthaler A, Honda K, Ludewig B, Ohashi PS, Lang KS. Hematopoietic cell-derived interferon controls viral replication and virus-induced disease. Blood. 113: 1045-52. PMID 18971424 DOI: 10.1182/Blood-2007-10-117861  0.627
2008 Lang PA, Contaldo C, Georgiev P, El-Badry AM, Recher M, Kurrer M, Cervantes-Barragan L, Ludewig B, Calzascia T, Bolinger B, Merkler D, Odermatt B, Bader M, Graf R, Clavien PA, et al. Aggravation of viral hepatitis by platelet-derived serotonin. Nature Medicine. 14: 756-61. PMID 18516052 DOI: 10.1038/Nm1780  0.58
2007 Lang KS, Hegazy AN, Lang PA, Eschli B, Löhning M, Hengartner H, Zinkernagel RM, Recher M. "Negative vaccination" by specific CD4 T cell tolerisation enhances virus-specific protective antibody responses. Plos One. 2: e1162. PMID 18000535 DOI: 10.1371/Journal.Pone.0001162  0.44
2007 Recher M, Lang KS, Navarini A, Hunziker L, Lang PA, Fink K, Freigang S, Georgiev P, Hangartner L, Zellweger R, Bergthaler A, Hegazy AN, Eschli B, Theocharides A, Jeker LT, et al. Extralymphatic virus sanctuaries as a consequence of potent T-cell activation. Nature Medicine. 13: 1316-23. PMID 17982463 DOI: 10.1038/Nm1670  0.483
2007 Junt T, Moseman EA, Iannacone M, Massberg S, Lang PA, Boes M, Fink K, Henrickson SE, Shayakhmetov DM, Di Paolo NC, van Rooijen N, Mempel TR, Whelan SP, von Andrian UH. Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells. Nature. 450: 110-4. PMID 17934446 DOI: 10.1038/Nature06287  0.393
2007 Lang KS, Burow A, Kurrer M, Lang PA, Recher M. The role of the innate immune response in autoimmune disease. Journal of Autoimmunity. 29: 206-12. PMID 17904335 DOI: 10.1016/J.Jaut.2007.07.018  0.396
2007 Lang F, Föller M, Lang K, Lang P, Ritter M, Vereninov A, Szabo I, Huber SM, Gulbins E. Cell volume regulatory ion channels in cell proliferation and cell death. Methods in Enzymology. 428: 209-25. PMID 17875419 DOI: 10.1016/S0076-6879(07)28011-5  0.37
2007 Lang KS, Navarini AA, Recher M, Lang PA, Heikenwalder M, Stecher B, Bergthaler A, Odermatt B, Akira S, Honda K, Hengartner H, Zinkernagel RM. MyD88 protects from lethal encephalitis during infection with vesicular stomatitis virus. European Journal of Immunology. 37: 2434-40. PMID 17668900 DOI: 10.1002/Eji.200737310  0.415
2007 Lang PA, Schenck M, Nicolay JP, Becker JU, Kempe DS, Lupescu A, Koka S, Eisele K, Klarl BA, Rübben H, Schmid KW, Mann K, Hildenbrand S, Hefter H, Huber SM, et al. Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide. Nature Medicine. 13: 164-70. PMID 17259995 DOI: 10.1038/Nm1539  0.306
2007 Kempe DS, Akel A, Lang PA, Hermle T, Biswas R, Muresanu J, Friedrich B, Dreischer P, Wolz C, Schumacher U, Peschel A, Götz F, Döring G, Wieder T, Gulbins E, et al. Suicidal erythrocyte death in sepsis. Journal of Molecular Medicine (Berlin, Germany). 85: 273-81. PMID 17180345 DOI: 10.1007/S00109-006-0123-8  0.314
2006 Shumilina E, Kiedaisch V, Akkel A, Lang P, Hermle T, Kempe DS, Huber SM, Wieder T, Laufer S, Lang F. Stimulation of Suicidal Erythrocyte Death by Lipoxygenase Inhibitor Bay-Y5884 Cellular Physiology and Biochemistry. 18: 233-242. PMID 17167228 DOI: 10.1159/000097670  0.331
2006 Niemoeller OM, Akel A, Lang PA, Attanasio P, Kempe DS, Hermle T, Sobiesiak M, Wieder T, Lang F. Induction of eryptosis by cyclosporine. Naunyn-Schmiedeberg's Archives of Pharmacology. 374: 41-9. PMID 17019514 DOI: 10.1007/S00210-006-0099-5  0.316
2006 Lupescu A, Bock CT, Lang PA, Aberle S, Kaiser H, Kandolf R, Lang F. Phospholipase A2 activity-dependent stimulation of Ca2+ entry by human parvovirus B19 capsid protein VP1. Journal of Virology. 80: 11370-80. PMID 16956939 DOI: 10.1128/Jvi.01041-06  0.316
2006 Lang PA, Huober J, Bachmann C, Kempe DS, Sobiesiak M, Akel A, Niemoeller OM, Dreischer P, Eisele K, Klarl BA, Gulbins E, Lang F, Wieder T. Stimulation of erythrocyte phosphatidylserine exposure by paclitaxel. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 18: 151-64. PMID 16914900 DOI: 10.1159/000095190  0.326
2006 Lang F, Lang KS, Lang PA, Huber SM, Wieder T. Mechanisms and significance of eryptosis. Antioxidants & Redox Signaling. 8: 1183-92. PMID 16910766 DOI: 10.1089/Ars.2006.8.1183  0.33
2006 Lang F, Lang KS, Lang PA, Huber SM, Wieder T. Osmotic shock-induced suicidal death of erythrocytes Acta Physiologica. 187: 191-198. PMID 16734755 DOI: 10.1111/J.1748-1716.2006.01564.X  0.364
2006 Lang PA, Beringer O, Nicolay JP, Amon O, Kempe DS, Hermle T, Attanasio P, Akel A, Schäfer R, Friedrich B, Risler T, Baur M, Olbricht CJ, Zimmerhackl LB, Zipfel PF, et al. Suicidal death of erythrocytes in recurrent hemolytic uremic syndrome. Journal of Molecular Medicine (Berlin, Germany). 84: 378-88. PMID 16622713 DOI: 10.1007/S00109-006-0058-0  0.313
2006 Akel A, Hermle T, Niemoeller OM, Kempe DS, Lang PA, Attanasio P, Podolski M, Wieder T, Lang F. Stimulation of erythrocyte phosphatidylserine exposure by chlorpromazine. European Journal of Pharmacology. 532: 11-7. PMID 16472802 DOI: 10.1016/J.Ejphar.2005.12.037  0.314
2006 Kempe DS, Lang PA, Duranton C, Akel A, Lang KS, Huber SM, Wieder T, Lang F. Enhanced programmed cell death of iron-deficient erythrocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 368-70. PMID 16371427 DOI: 10.1096/Fj.05-4872Fje  0.301
2005 Lang F, Föller M, Lang KS, Lang PA, Ritter M, Gulbins E, Vereninov A, Huber SM. Ion channels in cell proliferation and apoptotic cell death Journal of Membrane Biology. 205: 147-157. PMID 16362503 DOI: 10.1007/S00232-005-0780-5  0.364
2005 Lang PA, Kempe DS, Akel A, Klarl BA, Eisele K, Podolski M, Hermle T, Niemoeller OM, Attanasio P, Huber SM, Wieder T, Lang F, Duranton C. Inhibition of erythrocyte "apoptosis" by catecholamines. Naunyn-Schmiedeberg's Archives of Pharmacology. 372: 228-35. PMID 16247607 DOI: 10.1007/S00210-005-0009-2  0.318
2005 Lang PA, Kempe DS, Myssina S, Tanneur V, Birka C, Laufer S, Lang F, Wieder T, Huber SM. PGE2 in the regulation of programmed erythrocyte death Cell Death and Differentiation. 12: 415-428. PMID 15746942 DOI: 10.1038/Sj.Cdd.4401561  0.315
2005 Lang PA, Kempe DS, Tanneur V, Eisele K, Klarl BA, Myssina S, Jendrossek V, Ishii S, Shimizu T, Waidmann M, Hessler G, Huber SM, Lang F, Wieder T. Stimulation of erythrocyte ceramide formation by platelet-activating factor. Journal of Cell Science. 118: 1233-43. PMID 15741229 DOI: 10.1242/Jcs.01730  0.33
2005 Wieder T, Lang PA, Lang KS, Kempe DS, Niemoeller OM, Duranton C, Gulbins E, Huber SM, Lang F. Studying mechanisms of eryptosis Cytotechnology. 49: 117-132. DOI: 10.1007/S10616-006-6335-5  0.313
2004 Lang F, Birka C, Myssina S, Lang KS, Lang PA, Tanneur V, Duranton C, Wieder T, Huber SM. Erythrocyte ion channels in regulation of apoptosis. Advances in Experimental Medicine and Biology. 559: 211-7. PMID 18727242 DOI: 10.1007/0-387-23752-6_20  0.353
2004 Lang F, Gulbins E, Szabo I, Lepple-Wienhues A, Huber SM, Duranton C, Lang KS, Lang PA, Wieder T. Cell volume and the regulation of apoptotic cell death. Journal of Molecular Recognition : Jmr. 17: 473-80. PMID 15362107 DOI: 10.1002/Jmr.705  0.419
2004 Birka C, Lang PA, Kempe DS, Hoefling L, Tanneur V, Duranton C, Nammi S, Henke G, Myssina S, Krikov M, Huber SM, Wieder T, Lang F. Enhanced susceptibility to erythrocyte "apoptosis" following phosphate depletion. PflüGers Archiv : European Journal of Physiology. 448: 471-7. PMID 15156318 DOI: 10.1007/S00424-004-1289-Y  0.368
2004 Lang F, Lang PA, Lang KS, Brand V, Tanneur V, Duranton C, Wieder T, Huber SM. Channel-induced apoptosis of infected host cells-the case of malaria. PflüGers Archiv : European Journal of Physiology. 448: 319-24. PMID 15042371 DOI: 10.1007/S00424-004-1254-9  0.337
2004 Lang KS, Myssina S, Brand V, Sandu C, Lang PA, Berchtold S, Huber SM, Lang F, Wieder T. Involvement of ceramide in hyperosmotic shock-induced death of erythrocytes. Cell Death and Differentiation. 11: 231-43. PMID 14615798 DOI: 10.1038/Sj.Cdd.4401311  0.343
2003 Lang PA, Warskulat U, Heller-Stilb B, Huang DY, Grenz A, Myssina S, Duszenko M, Lang F, Häussinger D, Vallon V, Wieder T. Blunted apoptosis of erythrocytes from taurine transporter deficient mice. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 13: 337-46. PMID 14631140 DOI: 10.1159/000075121  0.333
2003 Lang PA, Kaiser S, Myssina S, Wieder T, Lang F, Huber SM. Role of Ca2+-activated K+ channels in human erythrocyte apoptosis. American Journal of Physiology. Cell Physiology. 285: C1553-60. PMID 14600080 DOI: 10.1152/Ajpcell.00186.2003  0.328
2003 Myssina S, Huber SM, Birka C, Lang PA, Lang KS, Friedrich B, Risler T, Wieder T, Lang F. Inhibition of erythrocyte cation channels by erythropoietin. Journal of the American Society of Nephrology : Jasn. 14: 2750-7. PMID 14569084 DOI: 10.1097/01.Asn.0000093253.42641.C1  0.321
2003 Lang F, Lang KS, Wieder T, Myssina S, Birka C, Lang PA, Kaiser S, Kempe D, Duranton C, Huber SM. Cation channels, cell volume and the death of an erythrocyte. PflüGers Archiv : European Journal of Physiology. 447: 121-5. PMID 12905029 DOI: 10.1007/S00424-003-1150-8  0.339
2002 Wärntges S, Friedrich B, Henke G, Duranton C, Lang PA, Waldegger S, Meyermann R, Kuhl D, Speckmann EJ, Obermüller N, Witzgall R, Mack AF, Wagner HJ, Wagner A, Bröer S, et al. Cerebral localization and regulation of the cell volume-sensitive serum- and glucocorticoid-dependent kinase SGK1. Pflã¼Gers Archiv : European Journal of Physiology. 443: 617-24. PMID 11907829 DOI: 10.1007/S00424-001-0737-1  0.308
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