Scott E. Hemby - Publications

Affiliations: 
Wake Forest University School of Medicine, Winston-Salem, NC, United States 
Area:
synaptic pathology, cocaine, schizophrenia, antipsychotics, monkey, human, rat
Website:
http://www.wfubmc.edu/physpharm/faculty/hemby/

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Boateng CA, Nilson AN, Placide R, Pham ML, Jakobs FM, Boldizsar N, McIntosh S, Stallings LS, Korankyi IV, Kelshikar S, Shah N, Panasis D, Muccilli A, Ladik M, Maslonka B, ... ... Hemby SE, et al. Pharmacology and Therapeutic Potential of Benzothiazole Analogues for Cocaine Use Disorder. Journal of Medicinal Chemistry. PMID 37646374 DOI: 10.1021/acs.jmedchem.3c00734  0.307
2018 Hemby SE, McIntosh S, Leon F, Cutler SJ, McCurdy CR. Abuse liability and therapeutic potential of the Mitragyna speciosa (kratom) alkaloids mitragynine and 7-hydroxymitragynine. Addiction Biology. PMID 29949228 DOI: 10.1111/Adb.12639  0.342
2018 Chen R, McIntosh S, Hemby SE, Sun H, Sexton T, Martin T, Childers SR. High and low doses of cocaine intake are differentially regulated by dopamine D2 receptors in the ventral tegmental area and the nucleus accumbens. Neuroscience Letters. PMID 29454035 DOI: 10.1016/J.Neulet.2018.02.026  0.555
2016 Halene TB, Kozlenkov A, Jiang Y, Mitchell AC, Javidfar B, Dincer A, Park R, Wiseman J, Croxson PL, Giannaris EL, Hof PR, Roussos P, Dracheva S, Hemby SE, Akbarian S. NeuN(+) neuronal nuclei in non-human primate prefrontal cortex and subcortical white matter after clozapine exposure. Schizophrenia Research. PMID 26776227 DOI: 10.1016/J.Schres.2015.12.016  0.321
2015 McIntosh S, Sexton T, Pattison LP, Childers SR, Hemby SE. Increased Sensitivity to Cocaine Self-Administration in HIV-1 Transgenic Rats is Associated with Changes in Striatal Dopamine Transporter Binding. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 25749646 DOI: 10.1007/S11481-015-9594-0  0.755
2014 Pattison LP, McIntosh S, Sexton T, Childers SR, Hemby SE. Changes in dopamine transporter binding in nucleus accumbens following chronic self-administration cocaine: heroin combinations. Synapse (New York, N.Y.). 68: 437-44. PMID 24916769 DOI: 10.1002/Syn.21755  0.771
2014 Burnett EJ, Grant KA, Davenport AT, Hemby SE, Friedman DP. The effects of chronic ethanol self-administration on hippocampal 5-HT1A receptors in monkeys. Drug and Alcohol Dependence. 136: 135-42. PMID 24467872 DOI: 10.1016/J.Drugalcdep.2014.01.002  0.349
2014 Bough KJ, Amur S, Lao G, Hemby SE, Tannu NS, Kampman KM, Schmitz JM, Martinez D, Merchant KM, Green C, Sharma J, Dougherty AH, Moeller FG. Biomarkers for the development of new medications for cocaine dependence. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 202-19. PMID 23979119 DOI: 10.1038/Npp.2013.210  0.433
2013 McIntosh S, Howell L, Hemby SE. Dopaminergic dysregulation in prefrontal cortex of rhesus monkeys following cocaine self-administration. Frontiers in Psychiatry. 4: 88. PMID 23970867 DOI: 10.3389/fpsyt.2013.00088  0.518
2013 Chen J, Repunte-Canonigo V, Kawamura T, Lefebvre C, Shin W, Howell LL, Hemby SE, Harvey BK, Califano A, Morales M, Koob GF, Sanna PP. Hypothalamic proteoglycan syndecan-3 is a novel cocaine addiction resilience factor. Nature Communications. 4: 1955. PMID 23736082 DOI: 10.1038/Ncomms2955  0.52
2012 Pattison LP, McIntosh S, Budygin EA, Hemby SE. Differential regulation of accumbal dopamine transmission in rats following cocaine, heroin and speedball self-administration. Journal of Neurochemistry. 122: 138-46. PMID 22443145 DOI: 10.1111/J.1471-4159.2012.07738.X  0.779
2012 Ginsberg SD, Hemby SE, Smiley JF. Expression profiling in neuropsychiatric disorders: emphasis on glutamate receptors in bipolar disorder. Pharmacology, Biochemistry, and Behavior. 100: 705-11. PMID 22005598 DOI: 10.1016/j.pbb.2011.09.015  0.318
2011 Acosta G, Freidman DP, Grant KA, Hemby SE. Alternative splicing of AMPA subunits in prefrontal cortical fields of cynomolgus monkeys following chronic ethanol self-administration. Frontiers in Psychiatry. 2: 72. PMID 22291662 DOI: 10.3389/Fpsyt.2011.00072  0.346
2011 Pattison LP, Bonin KD, Hemby SE, Budygin EA. Speedball induced changes in electrically stimulated dopamine overflow in rat nucleus accumbens. Neuropharmacology. 60: 312-7. PMID 20869972 DOI: 10.1016/J.Neuropharm.2010.09.014  0.77
2010 Lynch WJ, Piehl KB, Acosta G, Peterson AB, Hemby SE. Aerobic exercise attenuates reinstatement of cocaine-seeking behavior and associated neuroadaptations in the prefrontal cortex. Biological Psychiatry. 68: 774-7. PMID 20692647 DOI: 10.1016/j.biopsych.2010.06.022  0.513
2010 Abdolahi A, Acosta G, Breslin FJ, Hemby SE, Lynch WJ. Incubation of nicotine seeking is associated with enhanced protein kinase A-regulated signaling of dopamine- and cAMP-regulated phosphoprotein of 32 kDa in the insular cortex. The European Journal of Neuroscience. 31: 733-41. PMID 20384816 DOI: 10.1111/j.1460-9568.2010.07114.x  0.403
2010 Hemby SE. Cocainomics: new insights into the molecular basis of cocaine addiction. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 5: 70-82. PMID 20084466 DOI: 10.1007/s11481-009-9189-8  0.462
2010 Acosta G, Hasenkamp W, Daunais JB, Friedman DP, Grant KA, Hemby SE. Ethanol self-administration modulation of NMDA receptor subunit and related synaptic protein mRNA expression in prefrontal cortical fields in cynomolgus monkeys. Brain Research. 1318: 144-54. PMID 20043891 DOI: 10.1016/J.Brainres.2009.12.050  0.701
2010 Tannu NS, Howell LL, Hemby SE. Integrative proteomic analysis of the nucleus accumbens in rhesus monkeys following cocaine self-administration. Molecular Psychiatry. 15: 185-203. PMID 18504425 DOI: 10.1038/Mp.2008.53  0.51
2009 Hemby SE, Tannu N. Modeling substance abuse for applications in proteomics. Methods in Molecular Biology (Clifton, N.J.). 566: 69-83. PMID 20058165 DOI: 10.1007/978-1-59745-562-6_5  0.454
2008 Backes EN, Hemby SE. Contribution of ventral tegmental GABA receptors to cocaine self-administration in rats. Neurochemical Research. 33: 459-67. PMID 17943439 DOI: 10.1007/s11064-007-9454-2  0.789
2007 O'Connor JA, Hemby SE. Elevated GRIA1 mRNA expression in Layer II/III and V pyramidal cells of the DLPFC in schizophrenia. Schizophrenia Research. 97: 277-88. PMID 17942280 DOI: 10.1016/j.schres.2007.09.022  0.494
2007 O'Connor JA, Muly EC, Arnold SE, Hemby SE. AMPA receptor subunit and splice variant expression in the DLPFC of schizophrenic subjects and rhesus monkeys chronically administered antipsychotic drugs. Schizophrenia Research. 90: 28-40. PMID 17141476 DOI: 10.1016/J.Schres.2006.10.004  0.527
2007 Tannu N, Mash DC, Hemby SE. Cytosolic proteomic alterations in the nucleus accumbens of cocaine overdose victims. Molecular Psychiatry. 12: 55-73. PMID 17075605 DOI: 10.1038/Sj.Mp.4001914  0.482
2007 Hemby SE, O'Connor JA. Transcriptional Regulation in Schizophrenia Adolescent Psychopathology and the Developing Brain: Integrating Brain and Prevention Science. DOI: 10.1093/acprof:oso/9780195306255.003.0005  0.377
2006 Hemby SE, O'connor JA, Acosta G, Floyd D, Anderson N, McCool BA, Friedman D, Grant KA. Ethanol-induced regulation of GABA-A subunit mRNAs in prefrontal fields of cynomolgus monkeys. Alcoholism, Clinical and Experimental Research. 30: 1978-85. PMID 17117962 DOI: 10.1111/J.1530-0277.2006.00254.X  0.512
2006 Hemby SE. Assessment of genome and proteome profiles in cocaine abuse. Progress in Brain Research. 158: 173-95. PMID 17027697 DOI: 10.1016/S0079-6123(06)58009-4  0.453
2006 O'Connor JA, Hasenkamp W, Horman BM, Muly EC, Hemby SE. Region specific regulation of NR1 in rhesus monkeys following chronic antipsychotic drug administration. Biological Psychiatry. 60: 659-62. PMID 16806093 DOI: 10.1016/j.biopsych.2006.03.044  0.738
2006 O'Connor J, Muly EC, Hemby SE. Molecular mapping of striatal subdivisions in juvenile Macaca Mulata. Experimental Neurology. 198: 326-37. PMID 16455077 DOI: 10.1016/J.Expneurol.2005.11.028  0.514
2006 Smith JE, Co C, Coller MD, Hemby SE, Martin TJ. Self-administered heroin and cocaine combinations in the rat: additive reinforcing effects-supra-additive effects on nucleus accumbens extracellular dopamine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 139-50. PMID 15956989 DOI: 10.1038/sj.npp.1300786  0.657
2005 Hemby SE, Tang W, Muly EC, Kuhar MJ, Howell L, Mash DC. Cocaine-induced alterations in nucleus accumbens ionotropic glutamate receptor subunits in human and non-human primates. Journal of Neurochemistry. 95: 1785-93. PMID 16363995 DOI: 10.1111/J.1471-4159.2005.03517.X  0.544
2005 Hemby SE, Horman B, Tang W. Differential regulation of ionotropic glutamate receptor subunits following cocaine self-administration. Brain Research. 1064: 75-82. PMID 16277980 DOI: 10.1016/j.brainres.2005.09.051  0.558
2004 Verkuyl JM, Hemby SE, Joëls M. Chronic stress attenuates GABAergic inhibition and alters gene expression of parvocellular neurons in rat hypothalamus. The European Journal of Neuroscience. 20: 1665-73. PMID 15355334 DOI: 10.1111/j.1460-9568.2004.03568.x  0.303
2004 Hemby SE. Morphine-induced alterations in gene expression of calbindin immunopositive neurons in nucleus accumbens shell and core. Neuroscience. 126: 689-703. PMID 15183518 DOI: 10.1016/j.neuroscience.2004.01.056  0.397
2004 Ginsberg SD, Elarova I, Ruben M, Tan F, Counts SE, Eberwine JH, Trojanowski JQ, Hemby SE, Mufson EJ, Che S. Single-cell gene expression analysis: implications for neurodegenerative and neuropsychiatric disorders. Neurochemical Research. 29: 1053-64. PMID 15176463 DOI: 10.1023/B:Nere.0000023593.77052.F7  0.556
2004 Tang W, Wesley M, Freeman WM, Liang B, Hemby SE. Alterations in ionotropic glutamate receptor subunits during binge cocaine self-administration and withdrawal in rats. Journal of Neurochemistry. 89: 1021-33. PMID 15140200 DOI: 10.1111/J.1471-4159.2004.02392.X  0.585
2003 Fasulo WH, Hemby SE. Time-dependent changes in gene expression profiles of midbrain dopamine neurons following haloperidol administration. Journal of Neurochemistry. 87: 205-19. PMID 12969267 DOI: 10.1046/j.1471-4159.2003.01986.x  0.389
2003 Backes E, Hemby SE. Discrete cell gene profiling of ventral tegmental dopamine neurons after acute and chronic cocaine self-administration. The Journal of Pharmacology and Experimental Therapeutics. 307: 450-9. PMID 12966149 DOI: 10.1124/jpet.103.054965  0.811
2003 Tang WX, Fasulo WH, Mash DC, Hemby SE. Molecular profiling of midbrain dopamine regions in cocaine overdose victims. Journal of Neurochemistry. 85: 911-24. PMID 12716423 DOI: 10.1046/J.1471-4159.2003.01740.X  0.567
2003 Hemby SE, Trojanowski JQ, Ginsberg SD. Neuron-specific age-related decreases in dopamine receptor subtype mRNAs. The Journal of Comparative Neurology. 456: 176-83. PMID 12509874 DOI: 10.1002/Cne.10525  0.376
2002 Hasenkamp W, Hemby SE. Functional genomics and psychiatric illness. Progress in Brain Research. 138: 375-93. PMID 12432779 DOI: 10.1016/S0079-6123(02)38087-7  0.664
2002 Hemby SE, Ginsberg SD, Brunk B, Arnold SE, Trojanowski JQ, Eberwine JH. Gene expression profile for schizophrenia: discrete neuron transcription patterns in the entorhinal cortex. Archives of General Psychiatry. 59: 631-40. PMID 12090816 DOI: 10.1001/Archpsyc.59.7.631  0.576
2000 Ginsberg SD, Hemby SE, Lee VM, Eberwine JH, Trojanowski JQ. Expression profile of transcripts in Alzheimer's disease tangle-bearing CA1 neurons. Annals of Neurology. 48: 77-87. PMID 10894219 DOI: 10.1002/1531-8249(200007)48:1<77::Aid-Ana12>3.0.Co;2-A  0.555
1999 Hemby SE. Recent advances in the biology of addiction. Current Psychiatry Reports. 1: 159-65. PMID 11122919 DOI: 10.1007/S11920-999-0026-9  0.384
1999 Ginsberg SD, Crino PB, Hemby SE, Weingarten JA, Lee VM, Eberwine JH, Trojanowski JQ. Predominance of neuronal mRNAs in individual Alzheimer's disease senile plaques. Annals of Neurology. 45: 174-81. PMID 9989619 DOI: 10.1002/1531-8249(199902)45:2<174::Aid-Ana7>3.0.Co;2-E  0.646
1999 Hemby SE, Co C, Dworkin SI, Smith JE. Synergistic elevations in nucleus accumbens extracellular dopamine concentrations during self-administration of cocaine/heroin combinations (Speedball) in rats. The Journal of Pharmacology and Experimental Therapeutics. 288: 274-80. PMID 9862781  0.614
1998 Crino P, Khodakhah K, Becker K, Ginsberg S, Hemby S, Eberwine J. Presence and phosphorylation of transcription factors in developing dendrites. Proceedings of the National Academy of Sciences of the United States of America. 95: 2313-8. PMID 9482882 DOI: 10.1073/pnas.95.5.2313  0.662
1997 Hemby SE, Co C, Koves TR, Smith JE, Dworkin SI. Differences in extracellular dopamine concentrations in the nucleus accumbens during response-dependent and response-independent cocaine administration in the rat. Psychopharmacology. 133: 7-16. PMID 9335075 DOI: 10.1007/S002130050365  0.652
1997 Hemby SE, Lucki I, Gatto G, Singh A, Thornley C, Matasi J, Kong N, Smith JE, Davies HM, Dworkin SI. Potential antidepressant effects of novel tropane compounds, selective for serotonin or dopamine transporters. The Journal of Pharmacology and Experimental Therapeutics. 282: 727-33. PMID 9262336  0.397
1996 Hemby SE, Smith JE, Dworkin SI. The effects of eticlopride and naltrexone on responding maintained by food, cocaine, heroin and cocaine/heroin combinations in rats. The Journal of Pharmacology and Experimental Therapeutics. 277: 1247-58. PMID 8667185  0.557
1996 Crino P, Hemby S, Eberwine J. Utility of in situ transcription, single-cell nucleic acid amplification and expression profiling in the study of the central nervous system development Cell Vision - Journal of Analytical Morphology. 3: 203-206.  0.476
1995 Hemby SE, Co C, Reboussin D, Davies HM, Dworkin SI, Smith JE. Comparison of a novel tropane analog of cocaine, 2 beta-propanoyl-3 beta-(4-tolyl) tropane with cocaine HCl in rats: nucleus accumbens extracellular dopamine concentration and motor activity. The Journal of Pharmacology and Experimental Therapeutics. 273: 656-66. PMID 7752068  0.587
1995 Hemby SE, Martin TJ, Co C, Dworkin SI, Smith JE. The effects of intravenous heroin administration on extracellular nucleus accumbens dopamine concentrations as determined by in vivo microdialysis. The Journal of Pharmacology and Experimental Therapeutics. 273: 591-8. PMID 7752060  0.537
1994 Hemby SE, Jones GH, Hubert GW, Neill DB, Justice JB. Assessment of the relative contribution of peripheral and central components in cocaine place conditioning. Pharmacology, Biochemistry, and Behavior. 47: 973-9. PMID 8029272 DOI: 10.1016/0091-3057(94)90306-9  0.545
1993 Hooks MS, Jones GH, Hemby SE, Justice JB. Environmental and pharmacological sensitization: effects of repeated administration of systemic or intra-nucleus accumbens cocaine. Psychopharmacology. 111: 109-16. PMID 7870925 DOI: 10.1007/Bf02257416  0.541
1992 Hemby SE, Jones GH, Justice JB, Neill DB. Conditioned locomotor activity but not conditioned place preference following intra-accumbens infusions of cocaine. Psychopharmacology. 106: 330-6. PMID 1570378 DOI: 10.1007/BF02245413  0.543
1992 Hemby SE, Jones GH, Neill DB, Justice JB. 6-Hydroxydopamine lesions of the medial prefrontal cortex fail to influence cocaine-induced place conditioning. Behavioural Brain Research. 49: 225-30. PMID 1388816 DOI: 10.1016/S0166-4328(05)80168-8  0.478
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