Douglas A. Hattendorf, Ph.D.

Institution:
University of Chicago, Chicago, IL
Area:
protein folding
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"Douglas Hattendorf"

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Susan L. Lindquist grad student 2001 Chicago
 (Multiple allosteric signaling events in the Hsp104 ATP hydrolysis cycle revealed by mutagenesis of conserved AAA active site residues.)
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Publications

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Colbert KN, Hattendorf DA, Weiss TM, et al. (2013) Syntaxin1a variants lacking an N-peptide or bearing the LE mutation bind to Munc18a in a closed conformation. Proceedings of the National Academy of Sciences of the United States of America. 110: 12637-42
Burkhardt P, Hattendorf DA, Weis WI, et al. (2008) Munc18a controls SNARE assembly through its interaction with the syntaxin N-peptide. The Embo Journal. 27: 923-33
Hattendorf DA, Andreeva A, Gangar A, et al. (2007) Structure of the yeast polarity protein Sro7 reveals a SNARE regulatory mechanism. Nature. 446: 567-71
Cashikar AG, Schirmer EC, Hattendorf DA, et al. (2002) Defining a pathway of communication from the C-terminal peptide binding domain to the N-terminal ATPase domain in a AAA protein. Molecular Cell. 9: 751-60
Hattendorf DA, Lindquist SL. (2002) Analysis of the AAA sensor-2 motif in the C-terminal ATPase domain of Hsp104 with a site-specific fluorescent probe of nucleotide binding. Proceedings of the National Academy of Sciences of the United States of America. 99: 2732-7
Hattendorf DA, Lindquist SL. (2002) Cooperative kinetics of both Hsp104 ATPase domains and interdomain communication revealed by AAA sensor-1 mutants. The Embo Journal. 21: 12-21
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