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Matthew C. LaFave, Ph.D.

Affiliations: 
Genetics & Molecular Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
recombination, DNA repair, meiosis
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"Matthew LaFave"

Parents

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Jeff Sekelsky grad student 2005-2011 UNC Chapel Hill
 (Detection and Analysis of Common Fragile Sites in Drosophila melanogaster.)
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Publications

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Varshney GK, Carrington B, Pei W, et al. (2016) A high-throughput functional genomics workflow based on CRISPR/Cas9-mediated targeted mutagenesis in zebrafish. Nature Protocols. 11: 2357-2375
Vrljicak P, Tao S, Varshney GK, et al. (2016) Genome-Wide Analysis of Transposon and Retroviral Insertions Reveals Preferential Integrations in Regions of DNA Flexibility. G3 (Bethesda, Md.)
van Belkum A, Soriaga LB, LaFave MC, et al. (2015) Phylogenetic Distribution of CRISPR-Cas Systems in Antibiotic-Resistant Pseudomonas aeruginosa. Mbio. 6
Seiler C, Gebhart N, Zhang Y, et al. (2015) Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish. Plos One. 10: e0131908
LaFave MC, Varshney GK, Burgess SM. (2015) GeIST: a pipeline for mapping integrated DNA elements. Bioinformatics (Oxford, England). 31: 3219-21
Varshney GK, Pei W, LaFave MC, et al. (2015) High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9. Genome Research. 25: 1030-42
Yin L, Maddison LA, Li M, et al. (2015) Multiplex Conditional Mutagenesis Using Transgenic Expression of Cas9 and sgRNAs. Genetics. 200: 431-41
Quach HN, Tao S, Vrljicak P, et al. (2015) A Multifunctional Mutagenesis System for Analysis of Gene Function in Zebrafish. G3 (Bethesda, Md.). 5: 1283-99
Chandler RJ, LaFave MC, Varshney GK, et al. (2015) Vector design influences hepatic genotoxicity after adeno-associated virus gene therapy. The Journal of Clinical Investigation. 125: 870-80
Renaud G, LaFave MC, Liang J, et al. (2014) trieFinder: an efficient program for annotating Digital Gene Expression (DGE) tags. Bmc Bioinformatics. 15: 329
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