Matthew C. LaFave, Ph.D.

Genetics & Molecular Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
recombination, DNA repair, meiosis
"Matthew LaFave"


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Jeff Sekelsky grad student 2005-2011 UNC Chapel Hill
 (Detection and Analysis of Common Fragile Sites in Drosophila melanogaster.)
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Chandler RJ, LaFave MC, Varshney GK, et al. (2016) Genotoxicity in Mice Following AAV Gene Delivery: A Safety Concern for Human Gene Therapy? Molecular Therapy : the Journal of the American Society of Gene Therapy. 24: 198-201
Vrljicak P, Tao S, Varshney GK, et al. (2016) Genome-Wide Analysis of Transposon and Retroviral Insertions Reveals Preferential Integrations in Regions of DNA Flexibility. G3 (Bethesda, Md.)
Marquart GD, Tabor KM, Brown M, et al. (2015) A 3D Searchable Database of Transgenic Zebrafish Gal4 and Cre Lines for Functional Neuroanatomy Studies. Frontiers in Neural Circuits. 9: 78
van Belkum A, Soriaga LB, LaFave MC, et al. (2015) Phylogenetic Distribution of CRISPR-Cas Systems in Antibiotic-Resistant Pseudomonas aeruginosa. Mbio. 6
Varshney GK, Pei W, LaFave MC, et al. (2015) High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9. Genome Research. 25: 1030-42
Yin L, Maddison LA, Li M, et al. (2015) Multiplex Conditional Mutagenesis Using Transgenic Expression of Cas9 and sgRNAs. Genetics. 200: 431-41
Quach HN, Tao S, Vrljicak P, et al. (2015) A Multifunctional Mutagenesis System for Analysis of Gene Function in Zebrafish. G3 (Bethesda, Md.). 5: 1283-99
Walia JS, Altaleb N, Bello A, et al. (2015) Long-term correction of sandhoff disease following intravenous delivery of rAAV9 to mouse neonates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 414-22
Renaud G, LaFave MC, Liang J, et al. (2014) trieFinder: an efficient program for annotating Digital Gene Expression (DGE) tags. Bmc Bioinformatics. 15: 329
LaFave MC, Varshney GK, Vemulapalli M, et al. (2014) A defined zebrafish line for high-throughput genetics and genomics: NHGRI-1. Genetics. 198: 167-70
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