Adam S. Sperling, Ph.D.

University of California, Los Angeles, Los Angeles, CA 
Chromosomal Structures and Gene Activity
"Adam Sperling"


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Michael Grunstein grad student 2009 UCLA
 (The function of the histone H3 N terminal tail in the formation of heterochromatin in the budding yeast, Saccharomyces cerevisiae.)
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Sperling AS, Jeong KS, Kitada T, et al. (2011) Topoisomerase II binds nucleosome-free DNA and acts redundantly with topoisomerase I to enhance recruitment of RNA Pol II in budding yeast. Proceedings of the National Academy of Sciences of the United States of America. 108: 12693-8
Kitada T, Schleker T, Sperling AS, et al. (2011) γH2A is a component of yeast heterochromatin required for telomere elongation. Cell Cycle (Georgetown, Tex.). 10: 293-300
Dowell NL, Sperling AS, Mason MJ, et al. (2010) Chromatin-dependent binding of the S. cerevisiae HMGB protein Nhp6A affects nucleosome dynamics and transcription. Genes & Development. 24: 2031-42
Sperling AS, Grunstein M. (2009) Histone H3 N-terminus regulates higher order structure of yeast heterochromatin. Proceedings of the National Academy of Sciences of the United States of America. 106: 13153-9
Xie W, Song C, Young NL, et al. (2009) Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells. Molecular Cell. 33: 417-27
Burgio G, La Rocca G, Sala A, et al. (2008) Genetic identification of a network of factors that functionally interact with the nucleosome remodeling ATPase ISWI. Plos Genetics. 4: e1000089
Armstrong JA, Sperling AS, Deuring R, et al. (2005) Genetic screens for enhancers of brahma reveal functional interactions between the BRM chromatin-remodeling complex and the delta-notch signal transduction pathway in Drosophila. Genetics. 170: 1761-74
Armstrong JA, Papoulas O, Daubresse G, et al. (2002) The Drosophila BRM complex facilitates global transcription by RNA polymerase II. The Embo Journal. 21: 5245-54
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