Karmella A. Haynes, Ph.D.
Affiliations: | Washington University, Saint Louis, St. Louis, MO |
Area:
the role that chromatin structure plays in gene regulationGoogle:
"Karmella Haynes"Parents
Sign in to add mentor| Sarah C.R. Elgin | grad student | 2006 | Washington University | |
| (Determinants of heterochromatin structure on Drosophila melanogaster chromosome four.) | ||||
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Publications
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| Haynes KA, Priode JH. (2022) Rapid Single-Pot Assembly of Modular Chromatin Proteins for Epigenetic Engineering. Methods in Molecular Biology (Clifton, N.J.). 2599: 191-214 |
| Franklin KA, Shields CE, Haynes KA. (2022) Beyond the marks: reader-effectors as drivers of epigenetics and chromatin engineering. Trends in Biochemical Sciences. 47: 417-432 |
| Daer R, Hamna F, Barrett CM, et al. (2020) Site-directed targeting of transcriptional activation-associated proteins to repressed chromatin restores CRISPR activity. Apl Bioengineering. 4: 016102 |
| Barrett CM, McCracken R, Elmer J, et al. (2020) Components from the Human c-myb Transcriptional Regulation System Reactivate Epigenetically Repressed Transgenes. International Journal of Molecular Sciences. 21 |
| Tekel SJ, Smith CL, Lopez B, et al. (2019) Engineered Orthogonal Quorum Sensing Systems for Synthetic Gene Regulation in . Frontiers in Bioengineering and Biotechnology. 7: 80 |
| Olney KC, Nyer DB, Vargas DA, et al. (2018) The synthetic histone-binding regulator protein PcTF activates interferon genes in breast cancer cells. Bmc Systems Biology. 12: 83 |
| Christensen MD, Nitiyanandan R, Meraji S, et al. (2018) An inhibitor screen identifies histone-modifying enzymes as mediators of polymer-mediated transgene expression from plasmid DNA. Journal of Controlled Release : Official Journal of the Controlled Release Society |
| Tekel SJ, Barrett CM, Vargas DA, et al. (2018) Design, construction, and validation of histone-binding effectors in vitro and in cells. Biochemistry |
| Tekel SJ, Vargas DA, Song L, et al. (2018) Tandem Histone-Binding Domains Enhance the Activity of a Synthetic Chromatin Effector. Acs Synthetic Biology |
| Nyer DB, Daer RM, Vargas D, et al. (2017) Regulation of cancer epigenomes with a histone-binding synthetic transcription factor. Npj Genomic Medicine. 2 |