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Nanhai He, Ph.D.

Affiliations: 
2012 Molecular & Cell Biology University of California, Berkeley, Berkeley, CA, United States 
Area:
Sex Chromosome Evolution
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"Nanhai He"
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Qi Zhou grad student 2012 UC Berkeley
 (Mechanistic insights into the roles of P-TEFb and its novel cofactors in tumorigenesis and HIV transcription.)

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Publications

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Chou S, Upton H, Bao K, et al. (2013) HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold. Proceedings of the National Academy of Sciences of the United States of America. 110: E123-31
He N, Chan CK, Sobhian B, et al. (2011) Human Polymerase-Associated Factor complex (PAFc) connects the Super Elongation Complex (SEC) to RNA polymerase II on chromatin. Proceedings of the National Academy of Sciences of the United States of America. 108: E636-45
He N, Zhou Q. (2011) New insights into the control of HIV-1 transcription: when Tat meets the 7SK snRNP and super elongation complex (SEC). Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 6: 260-8
He N, Liu M, Hsu J, et al. (2010) HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription. Molecular Cell. 38: 428-38
Chen R, Liu M, Li H, et al. (2008) PP2B and PP1alpha cooperatively disrupt 7SK snRNP to release P-TEFb for transcription in response to Ca2+ signaling. Genes & Development. 22: 1356-68
He N, Jahchan NS, Hong E, et al. (2008) A La-related protein modulates 7SK snRNP integrity to suppress P-TEFb-dependent transcriptional elongation and tumorigenesis. Molecular Cell. 29: 588-99
Yang Z, He N, Zhou Q. (2008) Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression. Molecular and Cellular Biology. 28: 967-76
He N, Pezda AC, Zhou Q. (2006) Modulation of a P-TEFb functional equilibrium for the global control of cell growth and differentiation. Molecular and Cellular Biology. 26: 7068-76
Yang Z, Yik JH, Chen R, et al. (2005) Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4. Molecular Cell. 19: 535-45
Pan D, He N, Yang Z, et al. (2005) Differential gene expression profile in hepatopancreas of WSSV-resistant shrimp (Penaeus japonicus) by suppression subtractive hybridization. Developmental and Comparative Immunology. 29: 103-12
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