Bruce A Edgar

Affiliations: 
1993-2009 Fred Hutchinson Cancer Research Center, Seattle, WA, United States 
 2009-2016 Ruprecht-Karls-Universität Heidelberg, Heidelberg, Baden-Württemberg, Germany 
 2016- Huntsman Cancer Institute University of Utah, Salt Lake City, UT 
Area:
cell growth and proliferation in the fruit fly, Drosophila melanogaster
Website:
https://medicine.utah.edu/faculty/mddetail.php?facultyID=u6000141
Google:
"Bruce Alexander Edgar" OR "Bruce A Edgar"

Parents

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Gerold Schubiger grad student 1987 University of Washington
 (Early events in Drosophila development)
Pat H. O'Farrell post-doc UCSF
Paul Nurse post-doc 1993 Oxford (PombeTree)

Collaborators

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Stephen Cohen collaborator
BETA: Related publications

Publications

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Tauc HM, Rodriguez-Fernandez IA, Hackney JA, et al. (2021) Age-related changes in Polycomb gene regulation disrupt lineage fidelity in intestinal stem cells. Elife. 10
Zhang P, Katzaroff AJ, Buttitta LA, et al. (2021) The Krüppel-like factor Cabut has cell cycle regulatory properties similar to E2F1. Proceedings of the National Academy of Sciences of the United States of America. 118
Zhang P, Edgar BA. (2020) Lipoic acid and autophagy: new insights into stem cell aging. Embo Reports. e202051175
Ahmed SMH, Maldera JA, Krunic D, et al. (2020) Fitness trade-offs incurred by ovary-to-gut steroid signalling in Drosophila. Nature
Patel PH, Pénalva C, Kardorff M, et al. (2019) Damage sensing by a Nox-Ask1-MKK3-p38 signaling pathway mediates regeneration in the adult Drosophila midgut. Nature Communications. 10: 4365
Zhang P, Holowatyj AN, Ulrich CM, et al. (2019) Tumor suppressive autophagy in intestinal stem cells controls gut homeostasis. Autophagy. 1-3
Zhang P, Holowatyj AN, Roy T, et al. (2019) An SH3PX1-Dependent Endocytosis-Autophagy Network Restrains Intestinal Stem Cell Proliferation by Counteracting EGFR-ERK Signaling. Developmental Cell
Øvrebø JI, Edgar BA. (2018) Polyploidy in tissue homeostasis and regeneration. Development (Cambridge, England). 145
Edgar BA, Grewal SS. (2017) Longer life through an odd Pol enzyme. Nature. 552: 182-183
Edgar BA, Grewal SS. (2017) Longer life through an odd Pol enzyme. Nature. 552: 182-183
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