Philip A. Beachy
Affiliations: | Biochemistry | Stanford University, Palo Alto, CA |
Area:
Hedgehog proteins and other extracellular signals in morphogenesisWebsite:
http://med.stanford.edu/profiles/Philip_Beachy/Google:
"Philip A. Beachy"Bio:
http://www.nasonline.org/member-directory/members/20002141.html
http://stemcell.stanford.edu/about/Laboratories/beachy/index.html
http://dx.doi.org/10.1073/pnas.0408740102
http://cancer.stanford.edu/features/faculty/beachy.html
http://searchworks.stanford.edu/view/1216459
Cross-listing: Chemistry Tree
Parents
Sign in to add mentor| David S. Hogness | grad student | 1986 | Stanford | |
| (The Ubx domain in the bithorax complex of Drosophila) | ||||
Children
Sign in to add trainee| Chien-Huan Chen | grad student | 2000 | Johns Hopkins |
| Yong Ma | grad student | 2003 | Johns Hopkins |
| Shenqin Yao | grad student | 2006 | Johns Hopkins |
| Sekyung Oh | grad student | 2008 | Johns Hopkins |
| Adrian Creanga | grad student | 2010 | Johns Hopkins |
| Michelle Monje | post-doc | (Neurotree) | |
| Wan-Jin Lu | post-doc | 2011- | Stanford (Stem Cell Tree) |
| James K. Chen | post-doc | 1999-2003 | Johns Hopkins (Chemistry Tree) |
| Lay Teng Ang | research scientist | 2018- | Stanford School of Medicine (Neurotree) |
BETA: Related publications
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Publications
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| Jones RC, Karkanias J, Krasnow MA, et al. (2022) The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans. Science (New York, N.Y.). 376: eabl4896 |
| Wang Q, Asarnow DE, Ding K, et al. (2021) Dispatched uses Na flux to power release of lipid-modified Hedgehog. Nature |
| Zhang Y, Lu WJ, Bulkley DP, et al. (2020) Hedgehog pathway activation through nanobody-mediated conformational blockade of the Patched sterol conduit. Proceedings of the National Academy of Sciences of the United States of America |
| Deshpande I, Liang J, Hedeen D, et al. (2019) Smoothened stimulation by membrane sterols drives Hedgehog pathway activity. Nature |
| Zhang Y, Bulkley DP, Xin Y, et al. (2018) Structural Basis for Cholesterol Transport-like Activity of the Hedgehog Receptor Patched. Cell |
| Raleigh DR, Sever N, Choksi PK, et al. (2018) Cilia-Associated Oxysterols Activate Smoothened. Molecular Cell. 72: 316-327.e5 |
| Beachy P, Cai S, Ma Y, et al. (2018) Abstract P5-03-11: Targeted disruption of transcriptional effector GLI2 attenuates breast tumor growth and metastasis Cancer Research. 78 |
| Kiss B, Kershner A, Lu W, et al. (2018) MP81-10 MOLECULAR CHARACTERIZATION OF THE MURINE URINARY BLADDER USING SINGLE CELL RNA SEQUENCING Journal of Urology. 199 |
| Lu WJ, Mann RK, Nguyen A, et al. (2017) Neuronal delivery of Hedgehog directs spatial patterning of taste organ regeneration. Proceedings of the National Academy of Sciences of the United States of America |
| Myers BR, Neahring L, Zhang Y, et al. (2017) Rapid, direct activity assays for Smoothened reveal Hedgehog pathway regulation by membrane cholesterol and extracellular sodium. Proceedings of the National Academy of Sciences of the United States of America |