Scott Barolo, Ph.D.

Cell & Developmental Biology University of Michigan Medical School, Ann Arbor, MI, United States 
cis-regulatory elements, enhancers, developmental cell signaling, enhancer evolution
"Barolo lab"
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Lorberbaum DS, Ramos AI, Peterson KA, et al. (2016) An ancient yet flexible cis-regulatory architecture allows localized Hedgehog tuning by patched/Ptch1. Elife. 5
Gurdziel K, Lorberbaum DS, Udager AM, et al. (2015) Identification and Validation of Novel Hedgehog-Responsive Enhancers Predicted by Computational Analysis of Ci/Gli Binding Site Density. Plos One. 10: e0145225
Lorberbaum DS, Barolo S. (2015) Enhancers: holding out for the right promoter. Current Biology : Cb. 25: R290-3
Blake VM, Barolo S. (2014) Genome evolution: How sister genes grow apart. Current Biology : Cb. 24: R695-7
Lorberbaum DS, Barolo S. (2013) Gene regulation: when analog beats digital. Current Biology : Cb. 23: R1054-6
Ramos AI, Barolo S. (2013) Low-affinity transcription factor binding sites shape morphogen responses and enhancer evolution. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 368: 20130018
Ramos AI, Barolo S. (2012) Evolution of gene regulation: hybrid networks breed diversity. Current Biology : Cb. 22: R1009-11
White MA, Parker DS, Barolo S, et al. (2012) A model of spatially restricted transcription in opposing gradients of activators and repressors. Molecular Systems Biology. 8: 614
Evans NC, Swanson CI, Barolo S. (2012) Sparkling insights into enhancer structure, function, and evolution. Current Topics in Developmental Biology. 98: 97-120
Barolo S. (2012) Shadow enhancers: frequently asked questions about distributed cis-regulatory information and enhancer redundancy. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 34: 135-41
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