Alan Garen
Affiliations: | Molecular Biophysics and Biochemistry | Yale University, New Haven, CT |
Area:
Development; Genetics; Medical Sciences; Molecular BiologyWebsite:
http://medicine.yale.edu/mbb/faculty/alan_garen.profileGoogle:
"Alan Garen"Bio:
http://www.nasonline.org/member-directory/members/55466.html
http://bbs.yale.edu/people/alan_garen.profile
https://www.gf.org/fellows/all-fellows/alan-garen/
https://scholar.colorado.edu/concern/graduate_thesis_or_dissertations/5h73pw30w
Cross-listing: Chemistry Tree
Parents
Sign in to add mentor| Theodore T. Puck | grad student | 1953 | CU Boulder | |
| (Thermodynamic and kinetic studies on the attachment of T1 bacteriophage to bacteria) | ||||
Children
Sign in to add trainee| Martin G. Weigert | grad student | 1965 | Penn (Chemistry Tree) |
| Michael Levine | grad student | 1981 | Yale |
| Steve Beckendorf | post-doc | ||
| Allen Shearn | post-doc |
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Publications
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| Garen A. (2016) From a retrovirus infection of mice to a long noncoding RNA that induces proto-oncogene transcription and oncogenesis via an epigenetic transcription switch. Signal Transduction and Targeted Therapy. 1: 16007 |
| Wang G, Cui Y, Zhang G, et al. (2009) Regulation of proto-oncogene transcription, cell proliferation, and tumorigenesis in mice by PSF protein and a VL30 noncoding RNA. Proceedings of the National Academy of Sciences of the United States of America. 106: 16794-8 |
| Garen A, Song X. (2008) Regulatory roles of tumor-suppressor proteins and noncoding RNA in cancer and normal cell functions. International Journal of Cancer. Journal International Du Cancer. 122: 1687-9 |
| Song X, Sun Y, Garen A. (2005) Roles of PSF protein and VL30 RNA in reversible gene regulation. Proceedings of the National Academy of Sciences of the United States of America. 102: 12189-93 |
| Song X, Sui A, Garen A. (2004) Binding of mouse VL30 retrotransposon RNA to PSF protein induces genes repressed by PSF: effects on steroidogenesis and oncogenesis. Proceedings of the National Academy of Sciences of the United States of America. 101: 621-6 |
| Song X, Wang B, Bromberg M, et al. (2002) Retroviral-mediated transmission of a mouse VL30 RNA to human melanoma cells promotes metastasis in an immunodeficient mouse model. Proceedings of the National Academy of Sciences of the United States of America. 99: 6269-73 |
| Bromberg ME, Sundaram R, Homer RJ, et al. (1999) Role of tissue factor in metastasis: functions of the cytoplasmic and extracellular domains of the molecule. Thrombosis and Haemostasis. 82: 88-92 |
| Hu Z, Sun Y, Garen A. (1999) Targeting tumor vasculature endothelial cells and tumor cells for immunotherapy of human melanoma in a mouse xenograft model. Proceedings of the National Academy of Sciences of the United States of America. 96: 8161-6 |
| Bromberg ME, Konigsberg WH, Madison JF, et al. (1995) Tissue factor promotes melanoma metastasis by a pathway independent of blood coagulation. Proceedings of the National Academy of Sciences of the United States of America. 92: 8205-9 |
| Raha D, Nguyen QD, Garen A. (1990) Molecular and developmental analyses of the protein encoded by the Drosophila gene ectodermal. Developmental Genetics. 11: 310-7 |