Nancy Mara Bonini
Affiliations: | Biology | University of Pennsylvania, Philadelphia, PA, United States |
Area:
transgenic models for human neurodegenerative diseaseWebsite:
https://www.bio.upenn.edu/people/nancy-boniniGoogle:
"Nancy Mara Bonini"Bio:
http://web.sas.upenn.edu/bonini-lab/
https://www.hhmi.org/scientists/nancy-m-bonini
https://books.google.com/books?id=SaVpAAAAMAAJ
Cross-listing: Neurotree
Parents
Sign in to add mentor| David Lee Nelson | grad student | 1987 | UW Madison (Chemistry Tree) | |
| (Regulation of Ciliary Motility in Paramecium by Cyclic AMP and Cyclic GMP: Behavioral and Biochemical Studies.) | ||||
| Seymour Benzer | post-doc | |||
Children
Sign in to add trainee| Pavan K. Auluck | grad student | 1998-2003 | Penn (Neurotree) |
| Julide Bilen | grad student | 2004 | Penn (Neurotree) |
| Marc Meulener | grad student | 2005 | Penn |
| Lingbo Li | grad student | 2006 | Penn |
| Melanie R. Watson | grad student | 2007 | Penn |
| Nan Liu | grad student | 2009 | Penn |
| Chantal Francis | grad student | 2011 | Penn |
| Shin-Yi Shieh | grad student | 2011 | Penn |
| Masashi Abe | grad student | 2013 | Penn |
| Mimi Cushman-Nick | grad student | 2013 | Penn |
| Ammar Naqvi | grad student | 2011-2016 | (Chemistry Tree) |
| Lindsey D. Goodman | grad student | 2012-2019 | Penn (Cell Biology Tree) |
| Edwin H. Chan | post-doc | ||
| John Warrick | post-doc | ||
| Yanshan L. Fang | post-doc | 2008-2013 | HHMI/UPenn (Neurotree) |
BETA: Related publications
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Publications
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| Goodman LD, Bonini NM. (2019) New Roles for Canonical Transcription Factors in Repeat Expansion Diseases. Trends in Genetics : Tig |
| Goodman LD, Bonini NM. (2019) Repeat-associated non-AUG (RAN) translation mechanisms running into focus for GGGGCC-repeat associated ALS/FTD. Progress in Neurobiology. 101697 |
| Goodman LD, Prudencio M, Kramer NJ, et al. (2019) Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD. Nature Neuroscience |
| Berson A, Goodman LD, Sartoris AN, et al. (2019) Drosophila Ref1/ALYREF regulates transcription and toxicity associated with ALS/FTD disease etiologies. Acta Neuropathologica Communications. 7: 65 |
| Goodman LD, Prudencio M, Srinivasan AR, et al. (2019) eIF4B and eIF4H mediate GR production from expanded G4C2 in a Drosophila model for C9orf72-associated ALS. Acta Neuropathologica Communications. 7: 62 |
| McGurk L, Gomes E, Guo L, et al. (2018) Poly(ADP-ribose) engages the TDP-43 nuclear-localization sequence to regulate granulo-filamentous aggregation. Biochemistry |
| Chung CY, Berson A, Kennerdell JR, et al. (2018) Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity. Nature Communications. 9: 4406 |
| Kennerdell JR, Liu N, Bonini NM. (2018) MiR-34 inhibits polycomb repressive complex 2 to modulate chaperone expression and promote healthy brain aging. Nature Communications. 9: 4188 |
| McGurk L, Mojsilovic-Petrovic J, Van Deerlin VM, et al. (2018) Nuclear poly(ADP-ribose) activity is a therapeutic target in amyotrophic lateral sclerosis. Acta Neuropathologica Communications. 6: 84 |
| McGurk L, Gomes E, Guo L, et al. (2018) Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization. Molecular Cell |