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Nancy Mara Bonini

Affiliations: 
Biology University of Pennsylvania, Philadelphia, PA, United States 
Area:
transgenic models for human neurodegenerative disease
Website:
https://www.bio.upenn.edu/people/nancy-bonini
Google:
"Nancy Mara Bonini"
Bio:

http://web.sas.upenn.edu/bonini-lab/
https://www.hhmi.org/scientists/nancy-m-bonini
https://books.google.com/books?id=SaVpAAAAMAAJ

Cross-listing: Neurotree

Parents

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David Lee Nelson grad student 1987 UW Madison (Chemistry Tree)
 (Regulation of Ciliary Motility in Paramecium by Cyclic AMP and Cyclic GMP: Behavioral and Biochemical Studies.)
Seymour Benzer post-doc

Children

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Pavan  K. Auluck grad student 1998-2003 Penn (Neurotree)
Julide Bilen grad student 2004 Penn (Neurotree)
Marc Meulener grad student 2005 Penn
Lingbo Li grad student 2006 Penn
Melanie R. Watson grad student 2007 Penn
Nan Liu grad student 2009 Penn
Chantal Francis grad student 2011 Penn
Shin-Yi Shieh grad student 2011 Penn
Masashi Abe grad student 2013 Penn
Mimi Cushman-Nick grad student 2013 Penn
Ammar Naqvi grad student 2011-2016 (Chemistry Tree)
Lindsey D. Goodman grad student 2012-2019 Penn (Cell Biology Tree)
Edwin H. Chan post-doc
John Warrick post-doc
Yanshan L. Fang post-doc 2008-2013 HHMI/UPenn (Neurotree)

Collaborators

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Aaron D. Gitler collaborator 2004- Penn (Neurotree)
BETA: Related publications

Publications

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Goodman LD, Bonini NM. (2019) New Roles for Canonical Transcription Factors in Repeat Expansion Diseases. Trends in Genetics : Tig
Goodman LD, Bonini NM. (2019) Repeat-associated non-AUG (RAN) translation mechanisms running into focus for GGGGCC-repeat associated ALS/FTD. Progress in Neurobiology. 101697
Goodman LD, Prudencio M, Kramer NJ, et al. (2019) Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD. Nature Neuroscience
Berson A, Goodman LD, Sartoris AN, et al. (2019) Drosophila Ref1/ALYREF regulates transcription and toxicity associated with ALS/FTD disease etiologies. Acta Neuropathologica Communications. 7: 65
Goodman LD, Prudencio M, Srinivasan AR, et al. (2019) eIF4B and eIF4H mediate GR production from expanded G4C2 in a Drosophila model for C9orf72-associated ALS. Acta Neuropathologica Communications. 7: 62
McGurk L, Gomes E, Guo L, et al. (2018) Poly(ADP-ribose) engages the TDP-43 nuclear-localization sequence to regulate granulo-filamentous aggregation. Biochemistry
Chung CY, Berson A, Kennerdell JR, et al. (2018) Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity. Nature Communications. 9: 4406
Kennerdell JR, Liu N, Bonini NM. (2018) MiR-34 inhibits polycomb repressive complex 2 to modulate chaperone expression and promote healthy brain aging. Nature Communications. 9: 4188
McGurk L, Mojsilovic-Petrovic J, Van Deerlin VM, et al. (2018) Nuclear poly(ADP-ribose) activity is a therapeutic target in amyotrophic lateral sclerosis. Acta Neuropathologica Communications. 6: 84
McGurk L, Gomes E, Guo L, et al. (2018) Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization. Molecular Cell
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