Parents
Sign in to add mentor| Douglas Cavener | grad student | 2003 | Penn State | |
| (Investigation of the physiological roles of the PERK and GCN2 eIF2alpha kinases in mice.) | ||||
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Publications
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| Mack HID, Zhang P, Fonslow BR, et al. (2017) The protein kinase MBK-1 contributes to lifespan extension in daf-2 mutant and germline-deficient Caenorhabditis elegans. Aging |
| Liang SH, Zhang W, McGrath BC, et al. (2006) PERK (eIF2alpha kinase) is required to activate the stress-activated MAPKs and induce the expression of immediate-early genes upon disruption of ER calcium homoeostasis. The Biochemical Journal. 393: 201-9 |
| Owen CR, Kumar R, Zhang P, et al. (2005) PERK is responsible for the increased phosphorylation of eIF2alpha and the severe inhibition of protein synthesis after transient global brain ischemia. Journal of Neurochemistry. 94: 1235-42 |
| Li Y, Iida K, O'Neil J, et al. (2003) PERK eIF2alpha kinase regulates neonatal growth by controlling the expression of circulating insulin-like growth factor-I derived from the liver. Endocrinology. 144: 3505-13 |
| Lee AV, Zhang P, Ivanova M, et al. (2003) Developmental and hormonal signals dramatically alter the localization and abundance of insulin receptor substrate proteins in the mammary gland. Endocrinology. 144: 2683-94 |
| Zhang P, McGrath BC, Reinert J, et al. (2002) The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice. Molecular and Cellular Biology. 22: 6681-8 |
| Zhang P, McGrath B, Li S, et al. (2002) The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas. Molecular and Cellular Biology. 22: 3864-74 |
| Kumar R, Azam S, Sullivan JM, et al. (2001) Brain ischemia and reperfusion activates the eukaryotic initiation factor 2alpha kinase, PERK. Journal of Neurochemistry. 77: 1418-21 |