Hugh Willet Brock

"Hugh Brock"


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Samantha Beck grad student
Ester O'Dor grad student
Bob Argiropoulos grad student 2002 UBC
Jacob Hodgson post-doc
Bob Lansman post-doc


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Edward M. Berger collaborator
Tom Grigliatti collaborator
Pedro Santamaria collaborator
BETA: Related publications


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Li T, Hodgson JW, Petruk S, et al. (2017) Additional sex combs interacts with enhancer of zeste and trithorax and modulates levels of trimethylation on histone H3K4 and H3K27 during transcription of hsp70. Epigenetics & Chromatin. 10: 43
Petruk S, Cai J, Sussman R, et al. (2017) Delayed Accumulation of H3K27me3 on Nascent DNA Is Essential for Recruitment of Transcription Factors at Early Stages of Stem Cell Differentiation. Molecular Cell
L Black K, Petruk S, Fenstermaker TK, et al. (2016) Chromatin proteins and RNA are associated with DNA during all phases of mitosis. Cell Discovery. 2: 16038
Petruk S, Fenstermaker TK, Black KL, et al. (2016) Detection of RNA-DNA association by a proximity ligation-based method. Scientific Reports. 6: 27313
Dupont CA, Dardalhon-Cuménal D, Kyba M, et al. (2015) Drosophila Cyclin G and epigenetic maintenance of gene expression during development. Epigenetics & Chromatin. 8: 18
Petruk S, Black KL, Kovermann SK, et al. (2013) Stepwise histone modifications are mediated by multiple enzymes that rapidly associate with nascent DNA during replication. Nature Communications. 4: 2841
Yasunaga S, Ohtsubo M, Ohno Y, et al. (2013) Scmh1 has E3 ubiquitin ligase activity for geminin and histone H2A and regulates geminin stability directly or indirectly via transcriptional repression of Hoxa9 and Hoxb4. Molecular and Cellular Biology. 33: 644-60
Petruk S, Sedkov Y, Johnston DM, et al. (2012) TrxG and PcG proteins but not methylated histones remain associated with DNA through replication. Cell. 150: 922-33
Mohd-Sarip A, Lagarou A, Doyen CM, et al. (2012) Transcription-independent function of Polycomb group protein PSC in cell cycle control. Science (New York, N.Y.). 336: 744-7
Hodgson JW, Brock HW. (2011) Are polycomb group bodies gene silencing factories? Cell. 144: 170-1
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