Alex Whitworth

Affiliations: 
University of Sheffield, Sheffield, England, United Kingdom 
Website:
http://www.shef.ac.uk/bms/research/whitworth
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"Alex Whitworth"
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Publications

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Terriente-Felix A, Wilson EL, Whitworth AJ. (2020) Drosophila phosphatidylinositol-4 kinase fwd promotes mitochondrial fission and can suppress Pink1/parkin phenotypes. Plos Genetics. 16: e1008844
Lee JJ, Andreazza S, Whitworth AJ. (2020) The STING pathway does not contribute to behavioural or mitochondrial phenotypes in Drosophila Pink1/parkin or mtDNA mutator models. Scientific Reports. 10: 2693
De Lazzari F, Sandrelli F, Whitworth AJ, et al. (2020) Antioxidant Therapy in Parkinson's Disease: Insights from . Antioxidants (Basel, Switzerland). 9
Andreazza S, Samstag CL, Sanchez-Martinez A, et al. (2019) Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila. Nature Communications. 10: 3280
von Stockum S, Sanchez-Martinez A, Corrà S, et al. (2019) Inhibition of the deubiquitinase USP8 corrects a Drosophila PINK1 model of mitochondria dysfunction. Life Science Alliance. 2
Lovero D, Giordano L, Marsano RM, et al. (2018) Characterization of Drosophila ATPsynC mutants as a new model of mitochondrial ATP synthase disorders. Plos One. 13: e0201811
Schöndorf DC, Ivanyuk D, Baden P, et al. (2018) The NAD+ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC and Fly Models of Parkinson's Disease. Cell Reports. 23: 2976-2988
Biosa A, Sanchez-Martinez A, Filograna R, et al. (2018) Superoxide dismutating molecules rescue the toxic effects of PINK1 and parkin loss. Human Molecular Genetics
Lee JJ, Sanchez-Martinez A, Zarate AM, et al. (2018) Basal mitophagy is widespread inbut minimally affected by loss of Pink1 or parkin. The Journal of Cell Biology
Khalil B, Cabirol-Pol MJ, Miguel L, et al. (2017) Enhancing Mitofusin/Marf ameliorates neuromuscular dysfunction in Drosophila models of TDP-43 proteinopathies. Neurobiology of Aging. 54: 71-83
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