Ernesto Sanchez-Herrero

Affiliations: 
Centro de Biologia Molecular Severo Ochoa (Madrid), CSIC-UAM, Madrid, Comunidad de Madrid, Spain 
Area:
bithorax complex, organ size
Google:
"Ernesto Sanchez-Herrero"
Bio:

Ernesto was one of the first (if not THE first) student of Gines Morata. He was co-discoverer of the three lethal complementation groups within the BX-C: Ubx, abd-A and Abd-B. Each of these genes were shown by others to carry a homeobox sequence. Since then he has worked on the regulation and function of the BX-C genes, including lately work on how Ubx shapes the Dpp gradient in the haltere and how this controls the size of this organ.

Cross-listing: Chemistry Tree

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Publications

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Garaulet DL, Castellanos MC, Bejarano F, et al. (2014) Homeotic function of Drosophila Bithorax-complex miRNAs mediates fertility by restricting multiple Hox genes and TALE cofactors in the CNS. Developmental Cell. 29: 635-48
Guarner A, Manjón C, Edwards K, et al. (2014) The zinc finger homeodomain-2 gene of Drosophila controls Notch targets and regulates apoptosis in the tarsal segments. Developmental Biology. 385: 350-65
Curt JR, de Navas LF, Sánchez-Herrero E. (2013) Differential activity of Drosophila Hox genes induces myosin expression and can maintain compartment boundaries. Plos One. 8: e57159
de Navas LF, Reed H, Akam M, et al. (2011) Integration of RNA processing and expression level control modulates the function of the Drosophila Hox gene Ultrabithorax during adult development. Development (Cambridge, England). 138: 107-16
Foronda D, de Navas LF, Garaulet DL, et al. (2009) Function and specificity of Hox genes. The International Journal of Developmental Biology. 53: 1404-19
Garaulet DL, Foronda D, Calleja M, et al. (2008) Polycomb-dependent Ultrabithorax Hox gene silencing induced by high Ultrabithorax levels in Drosophila. Development (Cambridge, England). 135: 3219-28
Manjón C, Sánchez-Herrero E, Suzanne M. (2007) Sharp boundaries of Dpp signalling trigger local cell death required for Drosophila leg morphogenesis. Nature Cell Biology. 9: 57-63
de Navas LF, Garaulet DL, Sánchez-Herrero E. (2006) The ultrabithorax Hox gene of Drosophila controls haltere size by regulating the Dpp pathway. Development (Cambridge, England). 133: 4495-506
de Navas L, Foronda D, Suzanne M, et al. (2006) A simple and efficient method to identify replacements of P-lacZ by P-Gal4 lines allows obtaining Gal4 insertions in the bithorax complex of Drosophila. Mechanisms of Development. 123: 860-7
Foronda D, Estrada B, de Navas L, et al. (2006) Requirement of Abdominal-A and Abdominal-B in the developing genitalia of Drosophila breaks the posterior downregulation rule. Development (Cambridge, England). 133: 117-27
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