Ernesto Sanchez-Herrero

Centro de Biologia Molecular Severo Ochoa (Madrid), CSIC-UAM, Madrid, Comunidad de Madrid, Spain 
bithorax complex, organ size
"Ernesto Sanchez-Herrero"

Ernesto was one of the first (if not THE first) student of Gines Morata. He was co-discoverer of the three lethal complementation groups within the BX-C: Ubx, abd-A and Abd-B. Each of these genes were shown by others to carry a homeobox sequence. Since then he has worked on the regulation and function of the BX-C genes, including lately work on how Ubx shapes the Dpp gradient in the haltere and how this controls the size of this organ.

Cross-listing: Chemistry Tree

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De Las Heras JM, García-Cortés C, Foronda D, et al. (2018) The Hox gene controls appendage shape by regulating extracellular matrix dynamics. Development (Cambridge, England)
Foronda D, Curt JR, Prieto N, et al. (2015) The elimination of an adult segment by the Hox gene Abdominal-B. Mechanisms of Development
de Navas L, Foronda D, Del Saz D, et al. (2014) A genetic strategy to obtain P-Gal4 elements in the Drosophila Hox genes. Methods in Molecular Biology (Clifton, N.J.). 1196: 49-57
Guarner A, Manjón C, Edwards K, et al. (2014) The zinc finger homeodomain-2 gene of Drosophila controls Notch targets and regulates apoptosis in the tarsal segments. Developmental Biology. 385: 350-65
Curt JR, de Navas LF, Sánchez-Herrero E. (2013) Differential activity of Drosophila Hox genes induces myosin expression and can maintain compartment boundaries. Plos One. 8: e57159
Foronda D, Martín P, Sánchez-Herrero E. (2012) Drosophila Hox and sex-determination genes control segment elimination through EGFR and extramacrochetae activity. Plos Genetics. 8: e1002874
de Navas LF, Reed H, Akam M, et al. (2011) Integration of RNA processing and expression level control modulates the function of the Drosophila Hox gene Ultrabithorax during adult development. Development (Cambridge, England). 138: 107-16
Foronda D, de Navas LF, Garaulet DL, et al. (2009) Function and specificity of Hox genes. The International Journal of Developmental Biology. 53: 1404-19
Garaulet DL, Foronda D, Calleja M, et al. (2008) Polycomb-dependent Ultrabithorax Hox gene silencing induced by high Ultrabithorax levels in Drosophila. Development (Cambridge, England). 135: 3219-28
de Navas LF, Garaulet DL, Sánchez-Herrero E. (2006) The ultrabithorax Hox gene of Drosophila controls haltere size by regulating the Dpp pathway. Development (Cambridge, England). 133: 4495-506
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