Julien Muffat
Affiliations: | 2017- | Neurosciences and Mental Health | The Hospital for Sick Children / University of Toronto, Toronto, Ontario, Canada |
Area:
stem cells, neurodegeneration, inflammation, pathological aging, microglia, neuro-immuneGoogle:
"Julien Muffat"Cross-listing: Neurotree
Parents
Sign in to add mentor| Alain Berthoz | research assistant | Whitehead Institute for Biomedical Research (Neurotree) | |
| Werner Graf | research assistant | CNRS, Collège de France (Neurotree) | |
| Gabriella Ugolini | research assistant | NBCM - CNRS Gif sur Yvette (Neurotree) | |
| David J. Anderson | grad student | Caltech (Neurotree) | |
| Henry A. Lester | grad student | Caltech (Neurotree) | |
| Rudolph E. Tanzi | grad student | Harvard Medical School (Neurotree) | |
| Seymour Benzer | grad student | 2002-2007 | Caltech |
| Rudolf Jaenisch | post-doc | 2009-2017 | Whitehead Institute for Biomedical Research (Neurotree) |
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Publications
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| Bhattacharya A, Choi WWY, Muffat J, et al. (2021) Modeling developmental brain diseases using human pluripotent stem cell-derived brain organoids - progress and perspective. Journal of Molecular Biology. 167386 |
| Dhaliwal N, Choi WWY, Muffat J, et al. (2021) Modeling PTEN overexpression-induced microcephaly in human brain organoids. Molecular Brain. 14: 131 |
| Trapecar M, Wogram E, Svoboda D, et al. (2021) Human physiomimetic model integrating microphysiological systems of the gut, liver, and brain for studies of neurodegenerative diseases. Science Advances. 7 |
| Tian A, Muffat J, Li Y. (2020) Studying Human Neurodevelopment and Diseases Using 3D Brain Organoids. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 40: 1186-1193 |
| Li Y, Muffat J, Omer Javed A, et al. (2019) Genome-wide CRISPR screen for Zika virus resistance in human neural cells. Proceedings of the National Academy of Sciences of the United States of America |
| Omer Javed A, Li Y, Muffat J, et al. (2018) Microcephaly Modeling of Kinetochore Mutation Reveals a Brain-Specific Phenotype. Cell Reports. 25: 368-382.e5 |
| Muffat J, Li Y, Omer A, et al. (2018) Human induced pluripotent stem cell-derived glial cells and neural progenitors display divergent responses to Zika and dengue infections. Proceedings of the National Academy of Sciences of the United States of America |
| Liu XS, Wu H, Krzisch M, et al. (2018) Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene. Cell |
| Li Y, Muffat J, Omer A, et al. (2016) Induction of Expansion and Folding in Human Cerebral Organoids. Cell Stem Cell |
| Muffat J, Li Y, Jaenisch R. (2016) CNS disease models with human pluripotent stem cells in the CRISPR age. Current Opinion in Cell Biology. 43: 96-103 |