Subhash Chandra Lakhotia, Ph.D.
|1976-||Department of Zoology, Cytogenetics Lab.||Banaras Hindu University, Varanasi, India|
Area:Drosophila model: Stress genes, noncoding RNA, hsr omega, neurodegeneration, apoptosis, Ayurvedic biology
Born in 1945 at Churu (Rajasthan, India) with education at Churu and Kolkata (class 8 onwards).. Bachelors' (1964), Master's (1966) and Ph.D. (1970) degrees from University of Calcutta. Doctoral research related to dosage compensation in Drosophila, supervised by Prof. Ardhendu Sekhar Mukherjee (late), who did his Ph.D. under Prof. Curt Stern at California.
Subsequent research interests using the Drosophila model: heeterochromatin, chromosomal replication, gene expression, heat shock genes and their developmental roles and noncoding RNA. Current research interests on lncRNA (hsromega gene), Stress genes in tumor development and Ayurvedic Biology.
Research work carried out at University of Calcutta (Kolkata), University of Delhi, Gujarat University (Ahemdabad), Banaras Hindu University (Varanasi), Institute of Animal Genetics (Edinburgh), University of Nijmegen (Holland), MIT (USA).
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|Ray M, Lakhotia SC. (2019) Activated Ras/JNK driven Dilp8 in imaginal discs adversely affects organismal homeostasis during early pupal stage in Drosophila, a new checkpoint for development. Developmental Dynamics : An Official Publication of the American Association of Anatomists|
|Ray M, Acharya S, Shambhavi S, et al. (2019) Over-expression of Hsp83 in grossly depleted lncRNA background causes synthetic lethality and phenocopy in . Journal of Biosciences. 44|
|Ray M, Singh G, Lakhotia SC. (2019) Altered levels of hsromega lncRNAs further enhance ras signaling during ectopically activated ras induced R7 differentiation in Drosophila. Gene Expression Patterns : Gep|
|Lakhotia SC. (2019) Need for integration of Ayurveda with modern biology and medicine Proceedings of the Indian National Science Academy|
|Patwardhan B, Nagarkar S, Gadre SR, et al. (2018) A critical analysis of the ‘UGC-approved list of journals' Current Science. 114: 1299-1303|
|Lakhotia SC. (2018) Central dogma, Selfish DNA and noncoding RNAs: a historical perspective Proc Indian Natn Sci Acad. 84: 415-427|
|Rastogi S,Lakhotia SC, Singh RH. (2018) Ayurvedic Rasayana therapy: a rational understanding necessary for mass benefits In: Translational Ayurveda, (Ed. Sanjeev Rastogi), Springer Nature, Singapore. 77-99|
|Tiwari V, Saba K, Veeraiah P, et al. (2017) Amalaki Rasayana improved memory and neuronal metabolic activity in AbPP-PS1 mouse model of Alzheimer's disease. Journal of Biosciences. 42: 363-371|
|Saba K, Rajnala N, Veeraiah P, et al. (2017) Energetics of Excitatory and Inhibitory Neurotransmission in Aluminum Chloride Model of Alzheimer's Disease: Reversal of Behavioral and Metabolic Deficits by Rasa Sindoor. Frontiers in Molecular Neuroscience. 10: 323|
|Lakhotia SC. (2017) From Heterochromatin to Long Noncoding RNAs in Drosophila: Expanding the Arena of Gene Function and Regulation. Advances in Experimental Medicine and Biology. 1008: 75-118|