Phillip D. Zamore, Ph.D.

University of Massachusetts Medical School, Worcester, MA, United States 
RNA interference, RNAi, microRNAs, piRNAs, transposons
"Phillip Zamore"

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Arif A, Bailey S, Izumi N, et al. (2022) GTSF1 accelerates target RNA cleavage by PIWI-clade Argonaute proteins. Nature
Jouravleva K, Vega-Badillo J, Zamore PD. (2022) Principles and pitfalls of high-throughput analysis of microRNA-binding thermodynamics and kinetics by RNA Bind-n-Seq. Cell Reports Methods. 2: 100185
Gainetdinov I, Colpan C, Cecchini K, et al. (2021) Terminal modification, sequence, length, and PIWI-protein identity determine piRNA stability. Molecular Cell
Wu PH, Zamore PD. (2021) Defining the functions of PIWI-interacting RNAs. Nature Reviews. Molecular Cell Biology
Yu T, Fan K, Özata DM, et al. (2021) Long first exons and epigenetic marks distinguish conserved pachytene piRNA clusters from other mammalian genes. Nature Communications. 12: 73
Zamore PD. (2020) One small step for worms, one giant leap for small RNAs. Nature Reviews. Molecular Cell Biology
Wu PH, Fu Y, Cecchini K, et al. (2020) The evolutionarily conserved piRNA-producing locus pi6 is required for male mouse fertility. Nature Genetics
Özata DM, Yu T, Mou H, et al. (2020) Evolutionarily conserved pachytene piRNA loci are highly divergent among modern humans. Nature Ecology & Evolution. 4: 156-168
Xie J, Tai PWL, Brown A, et al. (2019) Effective and Accurate Gene Silencing by a Recombinant AAV-Compatible MicroRNA Scaffold. Molecular Therapy : the Journal of the American Society of Gene Therapy
Becker WR, Ober-Reynolds B, Jouravleva K, et al. (2019) High-Throughput Analysis Reveals Rules for Target RNA Binding and Cleavage by AGO2. Molecular Cell
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