J. Paul Taylor

Affiliations: 
St Jude Children's Research Hospital, New York, NY, United States 
Area:
neurodegeneration
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"J. Taylor"
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Publications

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Kim HJ, Mohassel P, Donkervoort S, et al. (2022) Heterozygous frameshift variants in HNRNPA2B1 cause early-onset oculopharyngeal muscular dystrophy. Nature Communications. 13: 2306
Nedelsky NB, Taylor JP. (2021) Pathological phase transitions in ALS-FTD impair dynamic RNA-protein granules. Rna (New York, N.Y.)
Beijer D, Kim HJ, Guo L, et al. (2021) Characterization of HNRNPA1 mutations defines diversity in pathogenic mechanisms and clinical presentation. Jci Insight. 6
Baek M, Choe YJ, Bannwarth S, et al. (2021) TDP-43 and PINK1 mediate CHCHD10 mutation-induced defects in Drosophila and in vitro. Nature Communications. 12: 1924
Zhang J, Velmeshev D, Hashimoto K, et al. (2020) Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency. Nature
Haenig C, Atias N, Taylor AK, et al. (2020) Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains. Cell Reports. 32: 108050
Lee AK, Klein J, Fon Tacer K, et al. (2020) Translational Repression of G3BP in Cancer and Germ Cells Suppresses Stress Granules and Enhances Stress Tolerance. Molecular Cell
Yang P, Mathieu C, Kolaitis RM, et al. (2020) G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules. Cell. 181: 325-345.e28
Batlle C, Yang P, Coughlin M, et al. (2020) hnRNPDL Phase Separation Is Regulated by Alternative Splicing and Disease-Causing Mutations Accelerate Its Aggregation. Cell Reports. 30: 1117-1128.e5
Farhan SMK, Howrigan DP, Abbott LE, et al. (2019) Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein. Nature Neuroscience
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