Hang Yin

Affiliations: 
Ottawa Health Research Institute, Ottawa, Ontario, Canada 
Area:
Satellite Stem Cells
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"Hang Yin"

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Haifan Lin grad student 2001-2007 Duke
 (Epigenetic function of Piwi and Piwi-interacting piRNAs in Drosophila.)
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Publications

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Wang Y, Zhang S, Li H, et al. (2020) Small-Molecule Modulators of Toll-like Receptors. Accounts of Chemical Research
Jiang S, Tanji H, Yin K, et al. (2020) Rationally designed small-molecule inhibitors targeting an unconventional pocket on the TLR8 protein-protein interface. Journal of Medicinal Chemistry
Peng Y, Zhang X, Zhang T, et al. (2019) Lovastatin inhibits Toll-like receptor 4 signaling in microglia by targeting its co-receptor myeloid differentiation protein 2 and attenuates neuropathic pain. Brain, Behavior, and Immunity
Zhang Y, Jin X, Liang J, et al. (2019) Extracellular vesicles derived from ODN-stimulated macrophages transfer and activate Cdc42 in recipient cells and thereby increase cellular permissiveness to EV uptake. Science Advances. 5: eaav1564
Hu Z, Tanji H, Jiang S, et al. (2018) Small-Molecule TLR8 Antagonists via Structure-Based Rational Design. Cell Chemical Biology
Zhang S, Hu Z, Tanji H, et al. (2017) Small-molecule inhibition of TLR8 through stabilization of its resting state. Nature Chemical Biology
Bhattacharyya S, Midwood KS, Yin H, et al. (2017) Toll-Like Receptor-4 Signaling Drives Persistent Fibroblast Activation and Prevents Fibrosis Resolution in Scleroderma. Advances in Wound Care. 6: 356-369
Kargas V, Marzinek JK, Holdbrook DA, et al. (2017) A Polar SxxS Motif Drives Assembly of the Transmembrane Domains of Toll-Like Receptor 4. Biochimica Et Biophysica Acta
Zhang L, Dewan V, Yin HH. (2017) Discovery of Small Molecules as Multi-Toll-like Receptor Agonists with Proinflammatory and Anticancer Activities. Journal of Medicinal Chemistry
Zeng X, Wu P, Yao C, et al. (2017) Small molecule and peptide recognition of protein transmembrane domains. Biochemistry
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