Peter J. Harte

Affiliations: 
Case Western Reserve University, Cleveland Heights, OH, United States 
Area:
Polycomb silencing, chromatin, aging
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"Peter Harte"
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Publications

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Du J, Zhang J, He T, et al. (2016) Stuxnet Facilitates the Degradation of Polycomb Protein during Development. Developmental Cell. 37: 507-519
Tie F, Banerjee R, Fu C, et al. (2016) Polycomb inhibits histone acetylation by CBP by binding directly to its catalytic domain. Proceedings of the National Academy of Sciences of the United States of America
Harte PJ, Ernst P. (2015) Harnessing gene repression to inhibit leukemia. Nature Medicine. 21: 308-10
Tie F, Banerjee R, Saiakhova AR, et al. (2014) Trithorax monomethylates histone H3K4 and interacts directly with CBP to promote H3K27 acetylation and antagonize Polycomb silencing. Development (Cambridge, England). 141: 1129-39
Mason-Suares H, Tie F, Yan CM, et al. (2013) Polycomb silencing of the Drosophila 4E-BP gene regulates imaginal disc cell growth. Developmental Biology. 380: 111-24
Tie F, Banerjee R, Conrad PA, et al. (2012) Histone demethylase UTX and chromatin remodeler BRM bind directly to CBP and modulate acetylation of histone H3 lysine 27. Molecular and Cellular Biology. 32: 2323-34
Stepanik VA, Harte PJ. (2012) A mutation in the E(Z) methyltransferase that increases trimethylation of histone H3 lysine 27 and causes inappropriate silencing of active Polycomb target genes. Developmental Biology. 364: 249-58
Lin N, Li X, Cui K, et al. (2011) A barrier-only boundary element delimits the formation of facultative heterochromatin in Drosophila melanogaster and vertebrates. Molecular and Cellular Biology. 31: 2729-41
Siebold AP, Banerjee R, Tie F, et al. (2010) Polycomb Repressive Complex 2 and Trithorax modulate Drosophila longevity and stress resistance. Proceedings of the National Academy of Sciences of the United States of America. 107: 169-74
Tie F, Banerjee R, Stratton CA, et al. (2009) CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing. Development (Cambridge, England). 136: 3131-41
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