Vikram Khurana
Affiliations: | Whitehead Institute, Cambridge, MA, United States |
Area:
Neurodegeneration (Drosophila, Yeast, Stem Cell)Google:
"Vikram Khurana"Cross-listing: Neurotree
Parents
Sign in to add mentor| Mel B. Feany | grad student | 2006 | Harvard (Neurotree) | |
| (Mitogenic signaling and cell-cycle activation mediate neurodegeneration in Drosophila.) | ||||
| Rudolf Jaenisch | post-doc | Whitehead Institute (Neurotree) | ||
| Susan L. Lindquist | post-doc | Whitehead Institute | ||
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Publications
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| Mesentier-Louro LA, Goldman C, Ndayisaba A, et al. (2025) Cholesterol-mediated Lysosomal Dysfunction in Astrocytes Promotes α-Synuclein Pathology in Human Brain Tissue. Biorxiv : the Preprint Server For Biology |
| Lam I, Ndayisaba A, Lewis AJ, et al. (2025) Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions. Neuron |
| Ndayisaba A, Halliday GM, Khurana V. (2024) Multiple System Atrophy: Pathology, Pathogenesis, and Path Forward. Annual Review of Pathology |
| Maltby CJ, Krans A, Grudzien SJ, et al. (2024) AAGGG repeat expansions trigger -independent synaptic dysregulation in human CANVAS neurons. Science Advances. 10: eadn2321 |
| Lam I, Ndayisaba A, Lewis AJ, et al. (2024) Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions. Neuron |
| Nazeen S, Wang X, Zielinski D, et al. (2024) Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies. Biorxiv : the Preprint Server For Biology |
| Santhosh Kumar S, Naseri NN, Pather SR, et al. (2024) Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons. Science Advances. 10: eadj4767 |
| Maltby CJ, Krans A, Grudzien SJ, et al. (2023) AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons. Biorxiv : the Preprint Server For Biology |
| Ndayisaba A, Pitaro AT, Willett AS, et al. (2022) Correction to: Clinical trial-ready patient cohorts for multiple system atrophy: coupling biospecimen and iPSC banking to longitudinal deep-phenotyping. Cerebellum (London, England) |
| Raja WK, Neves E, Burke C, et al. (2022) Patient-derived three-dimensional cortical neurospheres to model Parkinson's disease. Plos One. 17: e0277532 |