Vikram Khurana

Affiliations: 
Whitehead Institute, Cambridge, MA, United States 
Area:
Neurodegeneration (Drosophila, Yeast, Stem Cell)
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"Vikram Khurana"
Cross-listing: Neurotree

Parents

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Mel  B. Feany grad student 2006 Harvard (Neurotree)
 (Mitogenic signaling and cell-cycle activation mediate neurodegeneration in Drosophila.)
Rudolf Jaenisch post-doc Whitehead Institute (Neurotree)
Susan L. Lindquist post-doc Whitehead Institute
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Publications

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Nazeen S, Wang X, Zielinski D, et al. (2024) Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies. Biorxiv : the Preprint Server For Biology
Santhosh Kumar S, Naseri NN, Pather SR, et al. (2024) Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons. Science Advances. 10: eadj4767
Maltby CJ, Krans A, Grudzien SJ, et al. (2023) AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons. Biorxiv : the Preprint Server For Biology
Ndayisaba A, Pitaro AT, Willett AS, et al. (2022) Correction to: Clinical trial-ready patient cohorts for multiple system atrophy: coupling biospecimen and iPSC banking to longitudinal deep-phenotyping. Cerebellum (London, England)
Raja WK, Neves E, Burke C, et al. (2022) Patient-derived three-dimensional cortical neurospheres to model Parkinson's disease. Plos One. 17: e0277532
Ndayisaba A, Pitaro AT, Willett AS, et al. (2022) Clinical Trial-Ready Patient Cohorts for Multiple System Atrophy: Coupling Biospecimen and iPSC Banking to Longitudinal Deep-Phenotyping. Cerebellum (London, England)
Kim J, Young GS, Willett AS, et al. (2022) Toward More Accessible Fully Automated 3D Volumetric MRI Decision Trees for the Differential Diagnosis of Multiple System Atrophy, Related Disorders, and Age-Matched Healthy Subjects. Cerebellum (London, England)
Hallacli E, Kayatekin C, Nazeen S, et al. (2022) The Parkinson's disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability. Cell. 185: 2035-2056.e33
Carmona-Abellan M, Gabilondo I, Murueta-Goyena A, et al. (2019) Small fiber neuropathy and phosphorylated alpha-synuclein in the skin of E46K-SNCA mutation carriers. Parkinsonism & Related Disorders
Lam I, Hallacli E, Khurana V. (2019) Proteome-Scale Mapping of Perturbed Proteostasis in Living Cells. Cold Spring Harbor Perspectives in Biology
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