Matthew H. Sieber, Ph.D.

University of Texas Southwestern Medical Center, Dallas, TX, United States 
 2011 Human Genetics University of Utah, Salt Lake City, UT 
Molecular Biology
"Matthew Sieber"


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Carl Sennrich Thummel grad student 2011 University of Utah
 (Transcriptional regulation of lipid homeostasis in Drosophila.)
Allan Spradling post-doc Carnegie Institution for Science, Dept. of Embryology
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Yue S, Wang L, DeMartino GN, et al. (2022) Highly conserved shifts in ubiquitin-proteasome system (UPS) activity drive mitochondrial remodeling during quiescence. Nature Communications. 13: 4462
Hocaoglu H, Sieber M. (2022) Mitochondrial respiratory quiescence: A new model for examining the role of mitochondrial metabolism in development. Seminars in Cell & Developmental Biology
Hocaoglu H, Wang L, Yang M, et al. (2021) Heritable shifts in redox metabolites during mitochondrial quiescence reprogramme progeny metabolism. Nature Metabolism
Obniski R, Sieber M, Spradling AC. (2018) Dietary Lipids Modulate Notch Signaling and Influence Adult Intestinal Development and Metabolism in Drosophila. Developmental Cell
Sieber MH, Spradling AC. (2017) The role of metabolic states in development and disease. Current Opinion in Genetics & Development. 45: 58-68
Sieber MH, Thomsen MB, Spradling AC. (2016) Electron Transport Chain Remodeling by GSK3 during Oogenesis Connects Nutrient State to Reproduction. Cell. 164: 420-32
Sieber MH, Spradling AC. (2015) Steroid Signaling Establishes a Female Metabolic State and Regulates SREBP to Control Oocyte Lipid Accumulation. Current Biology : Cb. 25: 993-1004
Tennessen JM, Bertagnolli NM, Evans J, et al. (2014) Coordinated metabolic transitions during Drosophila embryogenesis and the onset of aerobic glycolysis. G3 (Bethesda, Md.). 4: 839-50
Sieber MH, Thummel CS. (2012) Coordination of triacylglycerol and cholesterol homeostasis by DHR96 and the Drosophila LipA homolog magro. Cell Metabolism. 15: 122-7
Sieber MH, Thummel CS. (2009) The DHR96 nuclear receptor controls triacylglycerol homeostasis in Drosophila. Cell Metabolism. 10: 481-90
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