Alan Jian Zhu, Ph.D.

2006-2013 Cleveland Clinic Lerner Research Institute / Case Western Reserve University School of Medicine 
 2013- School of Life Sciences and Center for Life Sciences Peking University, Beijing, Beijing Shi, China 
Temporal and spatial regulation of cell signaling in development and in disease
"Alan Jian Zhu"
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Zhang J, Du J, Lei C, et al. (2014) Ubpy controls the stability of the ESCRT-0 subunit Hrs in development Development (Cambridge). 141: 1473-1479
Geisbrecht ER, Sawant K, Su Y, et al. (2013) Genetic interaction screens identify a role for hedgehog signaling in Drosophila border cell migration. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 242: 414-31
Zhang J, Liu M, Su Y, et al. (2012) A targeted in vivo RNAi screen reveals deubiquitinases as new regulators of Notch signaling G3 (Bethesda, Md.). 2: 1563-1575
Du J, Zhang J, Su Y, et al. (2011) In vivo RNAi screen reveals neddylation genes as novel regulators of Hedgehog signaling. Plos One. 6: e24168
Su Y, Ospina JK, Zhang J, et al. (2011) Sequential phosphorylation of smoothened transduces graded hedgehog signaling. Science Signaling. 4: ra43
Huang X, Suyama K, Buchanan J, et al. (2005) A Drosophila model of the Niemann-Pick type C lysosome storage disease: dnpc1a is required for molting and sterol homeostasis. Development (Cambridge, England). 132: 5115-24
Zhu AJ, Scott MP. (2004) Incredible journey: how do developmental signals travel through tissue? Genes & Development. 18: 2985-97
Hwa JJ, Zhu AJ, Hiller MA, et al. (2004) Germ-line specific variants of components of the mitochondrial outer membrane import machinery in Drosophila. Febs Letters. 572: 141-6
Zhu AJ, Zheng L, Suyama K, et al. (2003) Altered localization of Drosophila Smoothened protein activates Hedgehog signal transduction. Genes & Development. 17: 1240-52
von Schlippe M, Marshall JF, Perry P, et al. (2000) Functional interaction between E-cadherin and alphav-containing integrins in carcinoma cells. Journal of Cell Science. 113: 425-37
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