Sidi Chen

Ecology and Evolution University of Chicago, Chicago, IL 
Evolution of novelties, genome evolution and phenotypic evolution
"Sidi Chen"


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Manyuan Long grad student 2005-2011 Yale
 (Origin of essential functions and evolution of phenotypes.)
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Yi S, Chen S, Zhang L, et al. (2016) Signal Transduction and Regulation: Insights into Evolution. Biomed Research International. 2016: 8604245
Chen S, Sanjana NE, Zheng K, et al. (2015) Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis. Cell. 160: 1246-60
Platt RJ, Chen S, Zhou Y, et al. (2014) CRISPR-Cas9 knockin mice for genome editing and cancer modeling. Cell. 159: 440-55
Xue W, Chen S, Yin H, et al. (2014) CRISPR-mediated direct mutation of cancer genes in the mouse liver. Nature. 514: 380-4
Chen S, Xue Y, Wu X, et al. (2014) Global microRNA depletion suppresses tumor angiogenesis. Genes & Development. 28: 1054-67
Wu X, Scott DA, Kriz AJ, et al. (2014) Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells. Nature Biotechnology. 32: 670-6
Yin H, Xue W, Chen S, et al. (2014) Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype. Nature Biotechnology. 32: 551-3
Long M, VanKuren NW, Chen S, et al. (2013) New gene evolution: little did we know. Annual Review of Genetics. 47: 307-33
Chen S, Krinsky BH, Long M. (2013) New genes as drivers of phenotypic evolution. Nature Reviews. Genetics. 14: 645-60
Ni X, Zhang YE, Nègre N, et al. (2012) Adaptive evolution and the birth of CTCF binding sites in the Drosophila genome. Plos Biology. 10: e1001420
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