Yadong Huang

Affiliations: 
Biomedical Sciences University of California, San Francisco, San Francisco, CA 
Area:
Neuroscience Biology, Biogeochemistry
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"Yadong Huang"
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Children

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Karen Ring grad student 2012 UCSF
Anna K. Gillespie grad student 2010-2015 UCSF (Gladstone Institutes) (Neurotree)
Emily A. Aery Jones grad student 2015-2019 UCSF (Gladstone Institutes) (Neurotree)
Jason S. Bant post-doc 2019- UCSF (Gladstone Institutes) (Neurotree)
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Publications

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Rao A, Chen N, Kim MJ, et al. (2023) Microglia Depletion Reduces Human Neuronal APOE4-Driven Pathologies in a Chimeric Alzheimer's Disease Model. Biorxiv : the Preprint Server For Biology
Krogsaeter EK, McKetney J, Marquez A, et al. (2023) Lysosomal proteomics reveals mechanisms of neuronal apoE4-associated lysosomal dysfunction. Biorxiv : the Preprint Server For Biology
Koutsodendris N, Blumenfeld J, Agrawal A, et al. (2023) APOE4-promoted gliosis and degeneration in tauopathy are ameliorated by pharmacological inhibition of HMGB1 release. Cell Reports. 113252
Jang SS, Tabuena DR, Grone B, et al. (2023) Neuronal apoE4 induces early hyperexcitability in select populations of hippocampal neurons by altering Nell2 expression. Biorxiv : the Preprint Server For Biology
Koutsodendris N, Blumenfeld J, Agrawal A, et al. (2023) Neuronal APOE4 removal protects against tau-mediated gliosis, neurodegeneration and myelin deficits. Nature Aging. 3: 275-296
Aery Jones EA, Rao A, Zilberter M, et al. (2021) Dentate gyrus and CA3 GABAergic interneurons bidirectionally modulate signatures of internal and external drive to CA1. Cell Reports. 37: 110159
Zalocusky KA, Najm R, Taubes AL, et al. (2021) Neuronal ApoE upregulates MHC-I expression to drive selective neurodegeneration in Alzheimer's disease. Nature Neuroscience
Najm R, Zalocusky KA, Zilberter M, et al. (2020) In Vivo Chimeric Alzheimer's Disease Modeling of Apolipoprotein E4 Toxicity in Human Neurons. Cell Reports. 32: 107962
Najm R, Rao A, Huang Y. (2020) Too Much Tau in Interneurons Impairs Adult Hippocampal Neurogenesis in Alzheimer's Disease. Cell Stem Cell. 26: 297-299
Jones EA, Gillespie AK, Yoon SY, et al. (2019) Early Hippocampal Sharp-Wave Ripple Deficits Predict Later Learning and Memory Impairments in an Alzheimer's Disease Mouse Model. Cell Reports. 29: 2123-2133.e4
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