Mark Seeger

Ohio State University, Columbus, Columbus, OH 
Drosophila midline axon guidance
"Mark Seeger"

Dr.Mark Seeger obtained his PhD under the mentorship of Dr.Thomas Kauffmann at Indiana University at Bloomington, working on pattern formation in early embryonic development of the fruitfly. He then worked with Dr.Corey Goodman at University of California, Berkeley understanding the molecular mechanisms of axon guidance.

Cross-listing: Neurotree


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Vicki L. McGovern grad student 2003 Ohio State (Neurotree)
Anil Kumar K. Challa grad student 1998-2003 Ohio State (Neurotree)
Laura A. Carver grad student 2011 Ohio State (Neurotree)
Julia Pinsonneault post-doc
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Dorsten JN, Varughese BE, Karmo S, et al. (2010) In the absence of frazzled over-expression of Abelson tyrosine kinase disrupts commissure formation and causes axons to leave the embryonic CNS. Plos One. 5: e9822
Challa AK, McWhorter ML, Wang C, et al. (2005) Robo3 isoforms have distinct roles during zebrafish development. Mechanisms of Development. 122: 1073-86
Forsthoefel DJ, Liebl EC, Kolodziej PA, et al. (2005) The Abelson tyrosine kinase, the Trio GEF and Enabled interact with the Netrin receptor Frazzled in Drosophila. Development (Cambridge, England). 132: 1983-94
McGovern VL, Pacak CA, Sewell ST, et al. (2003) A targeted gain of function screen in the embryonic CNS of Drosophila. Mechanisms of Development. 120: 1193-207
McGovern VL, Seeger MA. (2003) Mosaic analysis reveals a cell-autonomous, neuronal requirement for Commissureless in the Drosophila CNS. Development Genes and Evolution. 213: 500-4
Challa AK, Beattie CE, Seeger MA. (2001) Identification and characterization of roundabout orthologs in zebrafish. Mechanisms of Development. 101: 249-53
Frémion F, Darboux I, Diano M, et al. (2000) Amalgam is a ligand for the transmembrane receptor neurotactin and is required for neurotactin-mediated cell adhesion and axon fasciculation in Drosophila. The Embo Journal. 19: 4463-72
Liebl EC, Forsthoefel DJ, Franco LS, et al. (2000) Dosage-sensitive, reciprocal genetic interactions between the Abl tyrosine kinase and the putative GEF trio reveal trio's role in axon pathfinding. Neuron. 26: 107-18
Seeger MA, Beattie CE. (1999) Attraction versus repulsion: modular receptors make the difference in axon guidance. Cell. 97: 821-4
Tear G, Harris R, Sutaria S, et al. (1996) commissureless controls growth cone guidance across the CNS midline in Drosophila and encodes a novel membrane protein. Neuron. 16: 501-14
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