Jeffery W. Kelly, Ph.D.
Affiliations: | Chemistry and Molecular Medicine | Scripps Research Institute, La Jolla, La Jolla, CA, United States |
Area:
Chemical Biology, protein foldingWebsite:
http://www.scripps.edu/skaggs/kelly/dr_kelly.php?a=l&cid=1Google:
"Jeffery Kelly"Bio:
Shared the Wolf Prize in Chemistry 2023 "for developing a clinical strategy to ameliorate pathological protein aggregation."
Mean distance: 7.51 | S | N | B | C | P |
Parents
Sign in to add mentor| Slayton A. Evans | grad student | 1986 | UNC Chapel Hill | |
| (I. The mechanism, stereochemistry, and scope of dioxyphosphorane promoted cyclodehydrations ; II. Oxygen-17 NMR studies directed towards elucidating the structure and dynamics of oxygenated organosulfur and organosilicon compounds) | ||||
| Emil Thomas Kaiser | post-doc | 1989 | Rockefeller | |
Children
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Publications
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| Touvier T, Veneri FA, Claessens A, et al. (2024) Activation of XBP1s attenuates disease severity in models of proteotoxic Charcot-Marie-Tooth type 1B. Biorxiv : the Preprint Server For Biology |
| Xie L, Bowman ME, Louie GV, et al. (2023) Biochemistry and Protein Interactions of the CYREN Microprotein. Biochemistry |
| Kline GM, Paxman RJ, Lin CY, et al. (2023) Divergent Proteome Reactivity Influences Arm-Selective Activation of the Unfolded Protein Response by Pharmacological Endoplasmic Reticulum Proteostasis Regulators. Acs Chemical Biology |
| Perea V, Cole C, Lebeau J, et al. (2023) PERK signaling promotes mitochondrial elongation by remodeling membrane phosphatidic acid. The Embo Journal. e113908 |
| Elsasser S, Elia LP, Morimoto RI, et al. (2023) A Comprehensive Enumeration of the Human Proteostasis Network. 2. Components of the Autophagy-Lysosome Pathway. Biorxiv : the Preprint Server For Biology |
| Kline GM, Paxman RJ, Lin CY, et al. (2023) Divergent Proteome Reactivity Influences Arm-Selective Activation of Pharmacological Endoplasmic Reticulum Proteostasis Regulators. Biorxiv : the Preprint Server For Biology |
| Tsai FJ, Jaeger M, Coelho T, et al. (2023) Tafamidis concentration required for transthyretin stabilisation in cerebrospinal fluid. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 1-11 |
| Sun S, Wang C, Zhao P, et al. (2022) Capturing the conversion of the pathogenic alpha-1-antitrypsin fold by ATF6 enhanced proteostasis. Cell Chemical Biology |
| Tsai FJ, Nelson LT, Kline GM, et al. (2022) Characterising diflunisal as a transthyretin kinetic stabilizer at relevant concentrations in human plasma using subunit exchange. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 1-5 |
| Monteiro C, Mesgarzadeh JS, Anselmo J, et al. (2022) Tafamidis polyneuropathy amelioration requires modest increases in transthyretin stability even though increases in plasma native TTR and decreases in non-native TTR do not predict response. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 1-15 |