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Joseph P. Noel

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Enzymology, biosynthesis, structural biology, enzyme engineering, evolution, specialized metabolism, natural products, isoprenoids, polyketides
Website:
http://www-chem.ucsd.edu/faculty/profiles/noel_joseph_p.html
Google:
"Joseph Noel"
Mean distance: 9.2
 
SNBCP
Cross-listing: Plant Biology Tree

Parents

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Ming-Daw Tsai grad student 1990 Ohio State
 (Protein engineering of the lipolytic enzyme phospholipase A₂)
Paul B. Sigler post-doc 1993 Yale
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Publications

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Nartey CM, Koo HJ, Laurendon C, et al. (2024) Coevolutionary Information Captures Catalytic Functions and Reveals Divergent Roles of Terpene Synthase Interdomain Connections. Biochemistry
Chen A, Re RN, Davis TD, et al. (2024) Visualizing the Interface of Biotin and Fatty Acid Biosynthesis through SuFEx Probes. Journal of the American Chemical Society
Jiang Z, Chen A, Chen J, et al. (2023) Masked cerulenin enables a dual-site selective protein crosslink. Chemical Science. 14: 10925-10933
Chen A, Mindrebo JT, Davis TD, et al. (2022) Mechanism-based cross-linking probes capture the Escherichia coli ketosynthase FabB in conformationally distinct catalytic states. Acta Crystallographica. Section D, Structural Biology. 78: 1171-1179
Chen PY, Adak S, Chekan JR, et al. (2022) Structural Basis of Stereospecific Vanadium-Dependent Haloperoxidase Family Enzymes in Napyradiomycin Biosynthesis. Biochemistry
Mindrebo JT, Chen A, Kim WE, et al. (2021) Structure and mechanistic analyses of the gating mechanism of elongating ketosynthases. Acs Catalysis. 11: 6787-6799
Misson LE, Mindrebo JT, Davis TD, et al. (2020) Interfacial plasticity facilitates high reaction rate of FAS malonyl-CoA:ACP transacylase, FabD. Proceedings of the National Academy of Sciences of the United States of America
Mindrebo JT, Misson LE, Johnson C, et al. (2020) Activity Mapping the Acyl Carrier Protein - Elongating Ketosynthase Interaction in Fatty Acid Biosynthesis. Biochemistry
Chekan JR, McKinnie SMK, Noel JP, et al. (2020) Algal neurotoxin biosynthesis repurposes the terpene cyclase structural fold into an -prenyltransferase. Proceedings of the National Academy of Sciences of the United States of America
Lynch JH, Qian Y, Guo L, et al. (2020) Modulation of auxin formation by the cytosolic phenylalanine biosynthetic pathway. Nature Chemical Biology
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