Joseph P. Noel
Affiliations: | University of California, San Diego, La Jolla, CA |
Area:
Enzymology, biosynthesis, structural biology, enzyme engineering, evolution, specialized metabolism, natural products, isoprenoids, polyketidesWebsite:
http://www-chem.ucsd.edu/faculty/profiles/noel_joseph_p.htmlGoogle:
"Joseph Noel"Mean distance: 9.2 | S | N | B | C | P |
Cross-listing: Plant Biology Tree
Parents
Sign in to add mentorMing-Daw Tsai | grad student | 1990 | Ohio State | |
(Protein engineering of the lipolytic enzyme phospholipase A₂) | ||||
Paul B. Sigler | post-doc | 1993 | Yale |
Children
Sign in to add traineeChristopher R. Vickery | grad student | ||
Mark A. Verdecia | grad student | 2002 | UCSD |
Joseph Martin Jez | post-doc | Salk Institute | |
Rama Ranganathan | post-doc | Salk Institute (FlyTree) | |
Jing-Ke Weng | post-doc | 2009-2013 | Salk Institute |
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Publications
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Nartey CM, Koo HJ, Laurendon C, et al. (2024) Coevolutionary Information Captures Catalytic Functions and Reveals Divergent Roles of Terpene Synthase Interdomain Connections. Biochemistry |
Chen A, Re RN, Davis TD, et al. (2024) Visualizing the Interface of Biotin and Fatty Acid Biosynthesis through SuFEx Probes. Journal of the American Chemical Society |
Jiang Z, Chen A, Chen J, et al. (2023) Masked cerulenin enables a dual-site selective protein crosslink. Chemical Science. 14: 10925-10933 |
Chen A, Mindrebo JT, Davis TD, et al. (2022) Mechanism-based cross-linking probes capture the Escherichia coli ketosynthase FabB in conformationally distinct catalytic states. Acta Crystallographica. Section D, Structural Biology. 78: 1171-1179 |
Chen PY, Adak S, Chekan JR, et al. (2022) Structural Basis of Stereospecific Vanadium-Dependent Haloperoxidase Family Enzymes in Napyradiomycin Biosynthesis. Biochemistry |
Mindrebo JT, Chen A, Kim WE, et al. (2021) Structure and mechanistic analyses of the gating mechanism of elongating ketosynthases. Acs Catalysis. 11: 6787-6799 |
Misson LE, Mindrebo JT, Davis TD, et al. (2020) Interfacial plasticity facilitates high reaction rate of FAS malonyl-CoA:ACP transacylase, FabD. Proceedings of the National Academy of Sciences of the United States of America |
Mindrebo JT, Misson LE, Johnson C, et al. (2020) Activity Mapping the Acyl Carrier Protein - Elongating Ketosynthase Interaction in Fatty Acid Biosynthesis. Biochemistry |
Chekan JR, McKinnie SMK, Noel JP, et al. (2020) Algal neurotoxin biosynthesis repurposes the terpene cyclase structural fold into an -prenyltransferase. Proceedings of the National Academy of Sciences of the United States of America |
Lynch JH, Qian Y, Guo L, et al. (2020) Modulation of auxin formation by the cytosolic phenylalanine biosynthetic pathway. Nature Chemical Biology |