Mariann Bienz, PhD

Affiliations: 
MRC Laboratory of Molecular Biology, Cambridge, England, United Kingdom 
Area:
Wnt signalling
Website:
http://www2.mrc-lmb.cam.ac.uk/group-leaders/a-to-g/m-bienz
Google:
"Mariann Bienz"

Parents

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Peter Lawrence post-doc 1988-1990 MRC-LMB

Children

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Laurens Moore van Tienen grad student (Neurotree)
David Szuts grad student 1995-1999 (Chemistry Tree)
Barry J. Thompson grad student 2001-2004 MRC-LMB
BETA: Related publications

Publications

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Wang H, Bienz M, Yan XX, et al. (2023) Structural basis of the interaction between BCL9-Pygo and LDB-SSBP complexes in assembling the Wnt enhanceosome. Nature Communications. 14: 3702
Mieszczanek J, Strutt H, Rutherford TJ, et al. (2022) Selective function of the PDZ domain of Dishevelled in noncanonical Wnt signalling. Journal of Cell Science
Beitia GJ, Rutherford TJ, Freund SMV, et al. (2021) Regulation of Dishevelled DEP domain swapping by conserved phosphorylation sites. Proceedings of the National Academy of Sciences of the United States of America. 118
Gammons MV, Renko M, Flack JE, et al. (2020) Feedback control of Wnt signaling based on ultrastable histidine cluster co-aggregation between Naked/NKD and Axin. Elife. 9
Kan W, Enos MD, Korkmazhan E, et al. (2020) Limited Dishevelled/Axin oligomerization determines efficiency of Wnt/β-catenin signal transduction. Elife. 9
Yamanishi K, Fiedler M, Terawaki SI, et al. (2019) A direct heterotypic interaction between the DIX domains of Dishevelled and Axin mediates signaling to β-catenin. Science Signaling. 12
Renko M, Fiedler M, Rutherford TJ, et al. (2019) Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome. Proceedings of the National Academy of Sciences of the United States of America
Mieszczanek J, van Tienen LM, Ibrahim AEK, et al. (2019) Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models. Nature Communications. 10: 724
Gammons M, Bienz M. (2017) Multiprotein complexes governing Wnt signal transduction. Current Opinion in Cell Biology. 51: 42-49
Flack JE, Mieszczanek J, Novcic N, et al. (2017) Wnt-Dependent Inactivation of the Groucho/TLE Co-repressor by the HECT E3 Ubiquitin Ligase Hyd/UBR5. Molecular Cell
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