Marcel Wehrli

Oregon Health and Science University, Portland, OR 
Drosophila Wnt signaling
"Marcel Wehrli"


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Charles Weissmann research assistant 1986-1987 (Neurotree)
 (Diploma thesis (ETH))
Michael Wilcox grad student OHSU
Markus Noll grad student 1989-1992
 (External thesis)
Andrew Tomlinson post-doc 1993-1998 Columbia University Medical School
Stephen DiNardo post-doc 1998-2001 University of Pennsylvania School of Medicine
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Sopory S, Kwon S, Wehrli M, et al. (2010) Regulation of Dpp activity by tissue-specific cleavage of an upstream site within the prodomain. Developmental Biology. 346: 102-12
Kremer SA, Erdeniz N, Peterson-Nedry W, et al. (2010) In vivo analysis in Drosophila reveals differential requirements of contact residues in Axin for interactions with GSK3beta or beta-catenin. Developmental Biology. 337: 110-23
Peterson-Nedry W, Erdeniz N, Kremer S, et al. (2008) Unexpectedly robust assembly of the Axin destruction complex regulates Wnt/Wg signaling in Drosophila as revealed by analysis in vivo. Developmental Biology. 320: 226-41
Baig-Lewis S, Peterson-Nedry W, Wehrli M. (2007) Wingless/Wnt signal transduction requires distinct initiation and amplification steps that both depend on Arrow/LRP. Developmental Biology. 306: 94-111
Rives AF, Rochlin KM, Wehrli M, et al. (2006) Endocytic trafficking of Wingless and its receptors, Arrow and DFrizzled-2, in the Drosophila wing. Developmental Biology. 293: 268-83
Tolwinski NS, Wehrli M, Rives A, et al. (2003) Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/Gsk3beta activity. Developmental Cell. 4: 407-18
Wehrli M, Dougan ST, Caldwell K, et al. (2001) Erratum: correction: arrow encodes an LDL-receptor-related protein essential for Wingless signalling Nature. 410: 847-847
Wehrli M, Dougan ST, Caldwell K, et al. (2000) arrow encodes an LDL-receptor-related protein essential for Wingless signalling. Nature. 407: 527-30
Wehrli M, Tomlinson A. (1998) Independent regulation of anterior/posterior and equatorial/polar polarity in the Drosophila eye; evidence for the involvement of Wnt signaling in the equatorial/polar axis. Development (Cambridge, England). 125: 1421-32
Brower DL, Bunch TA, Mukai L, et al. (1995) Nonequivalent requirements for PS1 and PS2 integrin at cell attachments in Drosophila: genetic analysis of the alpha PS1 integrin subunit. Development (Cambridge, England). 121: 1311-20
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