Yi-Chen Hsieh

Affiliations: 
Baylor College of Medicine, Houston, TX 
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"Yi-Chen Hsieh"
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Hsieh YC, Augur ZM, Arbery M, et al. (2024) Person-specific differences in ubiquitin-proteasome mediated proteostasis in human neurons. Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Lee H, Aylward AJ, Pearse RV, et al. (2023) Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer's disease risk gene SORL1. Cell Reports. 112994
Young-Pearse TL, Lee H, Hsieh YC, et al. (2023) Moving beyond amyloid and tau to capture the biological heterogeneity of Alzheimer's disease. Trends in Neurosciences
Lee H, Aylward AJ, Pearse RV, et al. (2023) Cell-type-specific regulation of APOE levels in human neurons by the Alzheimer's disease risk gene SORL1. Biorxiv : the Preprint Server For Biology
Hsieh YC, Negri J, He A, et al. (2022) Elevated ganglioside GM2 activator (GM2A) in human brain tissue reduces neurite integrity and spontaneous neuronal activity. Molecular Neurodegeneration. 17: 61
Lagomarsino VN, Pearse RV, Liu L, et al. (2021) Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors. Neuron
Mangleburg CG, Wu T, Yalamanchili HK, et al. (2020) Integrated analysis of the aging brain transcriptome and proteome in tauopathy. Molecular Neurodegeneration. 15: 56
Hsieh YC, Guo C, Yalamanchili HK, et al. (2019) Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease. Cell Reports. 29: 301-316.e10
Guo C, Hsieh Y, Yalamanchili HK, et al. (2019) P4-130: Tau-Mediated Disruption Of The Spliceosome Triggers Cryptic Rna Splicing And Neurodegeneration In Alzheimer'S Disease Alzheimers & Dementia. 15
Guo C, Jeong HH, Hsieh YC, et al. (2018) Tau Activates Transposable Elements in Alzheimer's Disease. Cell Reports. 23: 2874-2880
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