Sarah J. Hernandez

Affiliations: 
University of California, Irvine, Irvine, CA 
Area:
Huntington's disease
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"Sarah Hernandez"

Parents

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Leslie Thompson post-doc 2015- (Neurotree)
Juan Botas research scientist 2018-
Katherine L. Thompson-Peer research scientist 2020-2022 UC Irvine (Neurotree)
 (visiting postdoc)
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Publications

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Reyes-Ortiz AM, Abud EM, Burns MS, et al. (2022) Single-nuclei transcriptome analysis of Huntington disease iPSC and mouse astrocytes implicates maturation and functional deficits. Iscience. 26: 105732
Hernandez SJ, Lim RG, Onur T, et al. (2022) An altered extracellular matrix-integrin interface contributes to Huntington's disease-associated CNS dysfunction in glial and vascular cells. Human Molecular Genetics
Hernandez SJ, Fote G, Reyes-Ortiz AM, et al. (2021) Cooperation of cell adhesion and autophagy in the brain: Functional roles in development and neurodegenerative disease. Matrix Biology Plus. 12: 100089
Smith-Geater C, Hernandez SJ, Lim RG, et al. (2020) Aberrant Development Corrected in Adult-Onset Huntington's Disease iPSC-Derived Neuronal Cultures via WNT Signaling Modulation. Stem Cell Reports
Ochaba J, Fote G, Kachemov M, et al. (2019) IKKβ slows Huntington's disease progression in R6/1 mice. Proceedings of the National Academy of Sciences of the United States of America
Morozko EL, Ochaba J, Hernandez SJ, et al. (2018) Longitudinal Biochemical Assay Analysis of Mutant Huntingtin Exon 1 Protein in R6/2 Mice. Journal of Huntington's Disease
Geater C, Hernandez S, Thompson L, et al. (2018) Cellular Models: HD Patient-Derived Pluripotent Stem Cells. Methods in Molecular Biology (Clifton, N.J.). 1780: 41-73
Hernandez SJ, Dolivo DM, Dominko T. (2017) PRMT8 demonstrates variant-specific expression in cancer cells and correlates with patient survival in breast, ovarian and gastric cancer. Oncology Letters. 13: 1983-1989
Dolivo D, Hernandez S, Dominko T. (2016) Cellular lifespan and senescence: a complex balance between multiple cellular pathways. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 38: S33-44
Hernandez S, Dominko T. (2016) Novel Protein Arginine Methyltransferase 8 Isoform Is Essential for Cell Proliferation. Journal of Cellular Biochemistry. 117: 2056-66
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