Leighton J. Core, Ph.D.

University of Connecticut, Storrs, CT, United States 
Transcription, Genomics
"Leighton Core"
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Sathyan KM, McKenna BD, Anderson WD, et al. (2019) An improved auxin-inducible degron system preserves native protein levels and enables rapid and specific protein depletion. Genes & Development
Zhang Z, Chng K, Lingadahalli S, et al. (2019) An AR-ERG transcriptional signature defined by long range chromatin interactomes in prostate cancer cells. Genome Research
Chu T, Rice EJ, Booth GT, et al. (2018) Chromatin run-on and sequencing maps the transcriptional regulatory landscape of glioblastoma multiforme. Nature Genetics
Duarte FM, Fuda NJ, Mahat DB, et al. (2016) Transcription factors GAF and HSF act at distinct regulatory steps to modulate stress-induced gene activation. Genes & Development
Mahat DB, Kwak H, Booth GT, et al. (2016) Base-pair-resolution genome-wide mapping of active RNA polymerases using precision nuclear run-on (PRO-seq). Nature Protocols. 11: 1455-1476
Andersson R, Chen Y, Core L, et al. (2015) Human Gene Promoters Are Intrinsically Bidirectional. Molecular Cell. 60: 346-7
Danko CG, Hyland SL, Core LJ, et al. (2015) Identification of active transcriptional regulatory elements from GRO-seq data. Nature Methods. 12: 433-8
Andersson R, Refsing Andersen P, Valen E, et al. (2014) Nuclear stability and transcriptional directionality separate functionally distinct RNA species. Nature Communications. 5: 5336
Core LJ, Martins AL, Danko CG, et al. (2014) Analysis of nascent RNA identifies a unified architecture of initiation regions at mammalian promoters and enhancers. Nature Genetics. 46: 1311-20
Wang IX, Core LJ, Kwak H, et al. (2014) RNA-DNA differences are generated in human cells within seconds after RNA exits polymerase II. Cell Reports. 6: 906-15
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