Jennifer C. Regan

Affiliations: 
University of Edinburgh, Edinburgh, Scotland, United Kingdom 
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"Jennifer Regan"
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Ureña E, Xu B, Regan JC, et al. (2024) Trametinib ameliorates aging-associated gut pathology in females by reducing Pol III activity in intestinal stem cells. Proceedings of the National Academy of Sciences of the United States of America. 121: e2311313121
Regan JC, Lu YX, Ureña E, et al. (2022) Sexual identity of enterocytes regulates autophagy to determine intestinal health, lifespan and responses to rapamycin. Nature Aging. 2: 1145-1158
Juricic P, Lu YX, Leech T, et al. (2022) Long-lasting geroprotection from brief rapamycin treatment in early adulthood by persistently increased intestinal autophagy. Nature Aging. 2: 824-836
Lu YX, Regan JC, Eßer J, et al. (2021) A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing. Elife. 10
Bjedov I, Cochemé HM, Foley A, et al. (2020) Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila. Plos Genetics. 16: e1009083
Bolukbasi E, Khericha M, Regan JC, et al. (2017) Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity. Cell Reports. 21: 641-653
Regan JC, Khericha M, Dobson AJ, et al. (2016) Sex difference in pathology of the ageing gut mediates the greater response of female lifespan to dietary restriction. Elife. 5
Regan JC, Partridge L. (2013) Gender and longevity: why do men die earlier than women? Comparative and experimental evidence. Best Practice & Research. Clinical Endocrinology & Metabolism. 27: 467-79
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