Tom Hartl

Affiliations: 
2008 Molecular University of Arizona, Tucson, AZ 
 2014 Developmental Biology Stanford University School of Medicine, Palo Alto, CA, United States 
 2014- Perlstein Lab, PBC 
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"Tom Hartl"

Parents

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Giovanni Bosco grad student 2008 University of Arizona
 (Condensin II chromosome individualization is necessary for meiotic segregation and antagonizes interphase chromosome alignment.)
Matthew P. Scott post-doc
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Publications

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Purzner T, Purzner J, Buckstaff T, et al. (2018) Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a therapeutic target in medulloblastoma. Science Signaling. 11
Eagen KP, Hartl TA, Kornberg RD. (2015) Stable Chromosome Condensation Revealed by Chromosome Conformation Capture. Cell. 163: 934-46
Ge X, Milenkovic L, Suyama K, et al. (2015) Phosphodiesterase 4D acts downstream of Neuropilin to control Hedgehog signal transduction and the growth of medulloblastoma. Elife. 4
Hartl TA, Scott MP. (2014) Wing tips: The wing disc as a platform for studying Hedgehog signaling. Methods (San Diego, Calif.). 68: 199-206
Smith HF, Roberts MA, Nguyen HQ, et al. (2013) Maintenance of interphase chromosome compaction and homolog pairing in Drosophila is regulated by the condensin cap-h2 and its partner Mrg15. Genetics. 195: 127-46
Buster DW, Daniel SG, Nguyen HQ, et al. (2013) SCFSlimb ubiquitin ligase suppresses condensin II-mediated nuclear reorganization by degrading Cap-H2. The Journal of Cell Biology. 201: 49-63
Hartl TA, Ni J, Cao J, et al. (2013) Regulation of ribosome biogenesis by nucleostemin 3 promotes local and systemic growth in Drosophila. Genetics. 194: 101-15
Bauer CR, Hartl TA, Bosco G. (2012) Condensin II promotes the formation of chromosome territories by inducing axial compaction of polyploid interphase chromosomes. Plos Genetics. 8: e1002873
Hartl TA, Smith HF, Bosco G. (2008) Chromosome alignment and transvection are antagonized by condensin II. Science (New York, N.Y.). 322: 1384-7
Hartl TA, Sweeney SJ, Knepler PJ, et al. (2008) Condensin II resolves chromosomal associations to enable anaphase I segregation in Drosophila male meiosis. Plos Genetics. 4: e1000228
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