Terry Watnick - Publications

Affiliations: 
University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Polycystins

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Hofherr A, Seger C, Fitzpatrick F, Busch T, Michel E, Luan J, Osterried L, Linden F, Kramer-Zucker A, Wakimoto B, Schütze C, Wiedemann N, Artati A, Adamski J, Walz G, ... ... Watnick T, et al. The mitochondrial transporter SLC25A25 links ciliary TRPP2 signaling and cellular metabolism. Plos Biology. 16: e2005651. PMID 30080851 DOI: 10.1371/journal.pbio.2005651  0.52
2018 Cai J, Song X, Wang W, Watnick T, Pei Y, Qian F, Pan D. A RhoA-YAP-c-Myc signaling axis promotes the development of polycystic kidney disease. Genes & Development. PMID 29891559 DOI: 10.1101/gad.315127.118  0.32
2018 Lin CC, Kurashige M, Liu Y, Terabayashi T, Ishimoto Y, Wang T, Choudhary V, Hobbs R, Liu LK, Lee PH, Outeda P, Zhou F, Restifo NP, Watnick T, Kawano H, et al. A cleavage product of Polycystin-1 is a mitochondrial matrix protein that affects mitochondria morphology and function when heterologously expressed. Scientific Reports. 8: 2743. PMID 29426897 DOI: 10.1038/s41598-018-20856-6  0.32
2017 Kaimori JY, Lin CC, Outeda P, Garcia-Gonzalez MA, Menezes LF, Hartung EA, Li A, Wu G, Fujita H, Sato Y, Nakanuma Y, Yamamoto S, Ichimaru N, Takahara S, Isaka Y, ... Watnick T, et al. NEDD4-family E3 ligase dysfunction due to PKHD1/Pkhd1 defects suggests a mechanistic model for ARPKD pathobiology. Scientific Reports. 7: 7733. PMID 28798345 DOI: 10.1038/s41598-017-08284-4  0.32
2017 Outeda P, Menezes L, Hartung EA, Bridges S, Zhou F, Zhu X, Xu H, Huang Q, Yao Q, Qian F, Germino GG, Watnick T. A novel model of autosomal recessive polycystic kidney questions the role of the fibrocystin C-terminus in disease mechanism. Kidney International. PMID 28729032 DOI: 10.1016/j.kint.2017.04.027  0.32
2016 Porath B, Gainullin VG, Cornec-Le Gall E, Dillinger EK, Heyer CM, Hopp K, Edwards ME, Madsen CD, Mauritz SR, Banks CJ, Baheti S, Reddy B, Herrero JI, Bañales JM, Hogan MC, ... ... Watnick TJ, et al. Mutations in GANAB, Encoding the Glucosidase IIα Subunit, Cause Autosomal-Dominant Polycystic Kidney and Liver Disease. American Journal of Human Genetics. 98: 1193-1207. PMID 27259053 DOI: 10.1016/j.ajhg.2016.05.004  0.52
2016 Kim S, Nie H, Nesin V, Tran U, Outeda P, Bai CX, Keeling J, Maskey D, Watnick T, Wessely O, Tsiokas L. The polycystin complex mediates Wnt/Ca(2+) signalling. Nature Cell Biology. PMID 27214281 DOI: 10.1038/ncb3363  0.52
2015 Perrone RD, Malek AM, Watnick T. Vascular complications in autosomal dominant polycystic kidney disease. Nature Reviews. Nephrology. PMID 26260542 DOI: 10.1038/nrneph.2015.128  0.52
2015 Chapman AB, Devuyst O, Eckardt KU, Gansevoort RT, Harris T, Horie S, Kasiske BL, Odland D, Pei Y, Perrone RD, Pirson Y, Schrier RW, Torra R, Torres VE, Watnick T, et al. Autosomal-dominant polycystic kidney disease (ADPKD): Executive summary from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference Kidney International. 88: 17-27. DOI: 10.1038/ki.2015.59  0.52
2014 Kim H, Xu H, Yao Q, Li W, Huang Q, Outeda P, Cebotaru V, Chiaravalli M, Boletta A, Piontek K, Germino GG, Weinman EJ, Watnick T, Qian F. Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism. Nature Communications. 5: 5482. PMID 25405894 DOI: 10.1038/ncomms6482  0.52
2014 Tan M, Wettersten HI, Chu K, Huso DL, Watnick T, Friedlander S, Landesman Y, Weiss RH. Novel inhibitors of nuclear transport cause cell cycle arrest and decrease cyst growth in ADPKD associated with decreased CDK4 levels. American Journal of Physiology. Renal Physiology. 307: F1179-86. PMID 25234309 DOI: 10.1152/ajprenal.00406.2014  0.52
2014 Outeda P, Huso DL, Fisher SA, Halushka MK, Kim H, Qian F, Germino GG, Watnick T. Polycystin signaling is required for directed endothelial cell migration and lymphatic development. Cell Reports. 7: 634-44. PMID 24767998 DOI: 10.1016/j.celrep.2014.03.064  0.52
2014 Fonseca JM, Bastos AP, Amaral AG, Sousa MF, Souza LE, Malheiros DM, Piontek K, Irigoyen MC, Watnick TJ, Onuchic LF. Renal cyst growth is the main determinant for hypertension and concentrating deficit in Pkd1-deficient mice. Kidney International. 85: 1137-50. PMID 24429399 DOI: 10.1038/ki.2013.501  0.52
2014 Liu D, Wang CJ, Judge DP, Halushka MK, Ni J, Habashi JP, Moslehi J, Bedja D, Gabrielson KL, Xu H, Qian F, Huso D, Dietz HC, Germino GG, Watnick T. A Pkd1-Fbn1 genetic interaction implicates TGF-β signaling in the pathogenesis of vascular complications in autosomal dominant polycystic kidney disease. Journal of the American Society of Nephrology : Jasn. 25: 81-91. PMID 24071006 DOI: 10.1681/ASN.2012050486  0.52
2013 Watnick TJ, Germino GG. Polycystic kidney disease: Polycystin-1 and polycystin-2--it's complicated. Nature Reviews. Nephrology. 9: 249-50. PMID 23567275 DOI: 10.1038/nrneph.2013.73  0.52
2012 Pei Y, Lan Z, Wang K, Garcia-Gonzalez M, He N, Dicks E, Parfrey P, Germino G, Watnick T. A missense mutation in PKD1 attenuates the severity of renal disease. Kidney International. 81: 412-7. PMID 22031115 DOI: 10.1038/ki.2011.370  0.52
2011 Higashihara E, Torres VE, Chapman AB, Grantham JJ, Bae K, Watnick TJ, Horie S, Nutahara K, Ouyang J, Krasa HB, Czerwiec FS. Tolvaptan in autosomal dominant polycystic kidney disease: three years' experience. Clinical Journal of the American Society of Nephrology : Cjasn. 6: 2499-507. PMID 21903984 DOI: 10.2215/CJN.03530411  0.52
2011 Köttgen M, Hofherr A, Li W, Chu K, Cook S, Montell C, Watnick T. Drosophila sperm swim backwards in the female reproductive tract and are activated via TRPP2 ion channels. Plos One. 6: e20031. PMID 21625494 DOI: 10.1371/journal.pone.0020031  0.52
2011 Talbot JJ, Shillingford JM, Vasanth S, Doerr N, Mukherjee S, Kinter MT, Watnick T, Weimbs T. Polycystin-1 regulates STAT activity by a dual mechanism. Proceedings of the National Academy of Sciences of the United States of America. 108: 7985-90. PMID 21518865 DOI: 10.1073/pnas.1103816108  0.52
2010 Garcia-Gonzalez MA, Outeda P, Zhou Q, Zhou F, Menezes LF, Qian F, Huso DL, Germino GG, Piontek KB, Watnick T. Pkd1 and Pkd2 are required for normal placental development. Plos One. 5. PMID 20862291 DOI: 10.1371/journal.pone.0012821  0.52
2010 Shah S, Watnick T, Atta MG. Not all renal cysts are created equal. Lancet (London, England). 376: 1024. PMID 20851261 DOI: 10.1016/S0140-6736(10)60956-7  0.52
2010 Watnick T, Germino GG. mTOR inhibitors in polycystic kidney disease. The New England Journal of Medicine. 363: 879-81. PMID 20581393 DOI: 10.1056/NEJMe1006925  0.52
2010 Kashtan CE, Segal Y, Flinter F, Makanjuola D, Gan JS, Watnick T. Aortic abnormalities in males with Alport syndrome. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 25: 3554-60. PMID 20494893 DOI: 10.1093/ndt/gfq271  0.52
2010 Pei Y, Watnick T. Diagnosis and screening of autosomal dominant polycystic kidney disease. Advances in Chronic Kidney Disease. 17: 140-52. PMID 20219617 DOI: 10.1053/j.ackd.2009.12.001  0.52
2010 Pei Y, Watnick T. Autosomal dominant polycystic kidney disease. Advances in Chronic Kidney Disease. 17: 115-7. PMID 20219614 DOI: 10.1053/j.ackd.2009.12.002  0.52
2009 Huang E, Samaniego-Picota M, McCune T, Melancon JK, Montgomery RA, Ugarte R, Kraus E, Womer K, Rabb H, Watnick T. DNA testing for live kidney donors at risk for autosomal dominant polycystic kidney disease. Transplantation. 87: 133-7. PMID 19136903 DOI: 10.1097/TP.0b013e318191e729  0.52
2009 Hartman TR, Liu D, Zilfou JT, Robb V, Morrison T, Watnick T, Henske EP. The tuberous sclerosis proteins regulate formation of the primary cilium via a rapamycin-insensitive and polycystin 1-independent pathway. Human Molecular Genetics. 18: 151-63. PMID 18845692 DOI: 10.1093/hmg/ddn325  0.52
2008 Köttgen M, Buchholz B, Garcia-Gonzalez MA, Kotsis F, Fu X, Doerken M, Boehlke C, Steffl D, Tauber R, Wegierski T, Nitschke R, Suzuki M, Kramer-Zucker A, Germino GG, Watnick T, et al. TRPP2 and TRPV4 form a polymodal sensory channel complex. The Journal of Cell Biology. 182: 437-47. PMID 18695040 DOI: 10.1083/jcb.200805124  0.52
2007 Tan PL, Barr T, Inglis PN, Mitsuma N, Huang SM, Garcia-Gonzalez MA, Bradley BA, Coforio S, Albrecht PJ, Watnick T, Germino GG, Beales PL, Caterina MJ, Leroux MR, Rice FL, et al. Loss of Bardet Biedl syndrome proteins causes defects in peripheral sensory innervation and function. Proceedings of the National Academy of Sciences of the United States of America. 104: 17524-9. PMID 17959775 DOI: 10.1073/pnas.0706618104  0.52
2007 Garcia-Gonzalez MA, Menezes LF, Piontek KB, Kaimori J, Huso DL, Watnick T, Onuchic LF, Guay-Woodford LM, Germino GG. Genetic interaction studies link autosomal dominant and recessive polycystic kidney disease in a common pathway. Human Molecular Genetics. 16: 1940-50. PMID 17575307 DOI: 10.1093/hmg/ddm141  0.52
2007 Garcia-Gonzalez MA, Jones JG, Allen SK, Palatucci CM, Batish SD, Seltzer WK, Lan Z, Allen E, Qian F, Lens XM, Pei Y, Germino GG, Watnick TJ. Evaluating the clinical utility of a molecular genetic test for polycystic kidney disease. Molecular Genetics and Metabolism. 92: 160-7. PMID 17574468 DOI: 10.1016/j.ymgme.2007.05.004  0.52
2003 Watnick TJ, Jin Y, Matunis E, Kernan MJ, Montell C. A flagellar polycystin-2 homolog required for male fertility in Drosophila. Current Biology : Cb. 13: 2179-84. PMID 14680634 DOI: 10.1016/j.cub.2003.12.002  0.52
2003 Watnick T, Germino G. From cilia to cyst. Nature Genetics. 34: 355-6. PMID 12923538 DOI: 10.1038/ng0803-355  0.52
2002 Qian F, Boletta A, Bhunia AK, Xu H, Liu L, Ahrabi AK, Watnick TJ, Zhou F, Germino GG. Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations. Proceedings of the National Academy of Sciences of the United States of America. 99: 16981-6. PMID 12482949 DOI: 10.1073/pnas.252484899  0.52
2001 Phakdeekitcharoen B, Watnick TJ, Germino GG. Mutation analysis of the entire replicated portion of PKD1 using genomic DNA samples. Journal of the American Society of Nephrology : Jasn. 12: 955-63. PMID 11316854  0.52
2001 Pei Y, Paterson AD, Wang KR, He N, Hefferton D, Watnick T, Germino GG, Parfrey P, Somlo S, St George-Hyslop P. Bilineal disease and trans-heterozygotes in autosomal dominant polycystic kidney disease. American Journal of Human Genetics. 68: 355-63. PMID 11156533 DOI: 10.1086/318188  0.52
2000 Phakdeekitcharoen B, Watnick TJ, Ahn C, Whang DY, Burkhart B, Germino GG. Thirteen novel mutations of the replicated region of PKD1 in an Asian population. Kidney International. 58: 1400-12. PMID 11012875 DOI: 10.1046/j.1523-1755.2000.00302.x  0.52
2000 Watnick T, He N, Wang K, Liang Y, Parfrey P, Hefferton D, St George-Hyslop P, Germino G, Pei Y. Mutations of PKD1 in ADPKD2 cysts suggest a pathogenic effect of trans-heterozygous mutations. Nature Genetics. 25: 143-4. PMID 10835625 DOI: 10.1038/75981  0.52
1999 Watnick T, Phakdeekitcharoen B, Johnson A, Gandolph M, Wang M, Briefel G, Klinger KW, Kimberling W, Gabow P, Germino GG. Mutation detection of PKD1 identifies a novel mutation common to three families with aneurysms and/or very-early-onset disease. American Journal of Human Genetics. 65: 1561-71. PMID 10577909 DOI: 10.1086/302657  0.52
1999 Reynolds DM, Hayashi T, Cai Y, Veldhuisen B, Watnick TJ, Lens XM, Mochizuki T, Qian F, Maeda Y, Li L, Fossdal R, Coto E, Wu G, Breuning MH, Germino GG, et al. Aberrant splicing in the PKD2 gene as a cause of polycystic kidney disease. Journal of the American Society of Nephrology : Jasn. 10: 2342-51. PMID 10541293  0.52
1999 Qian F, Watnick TJ. Somatic mutation as mechanism for cyst formation in autosomal dominant polycystic kidney disease. Molecular Genetics and Metabolism. 68: 237-42. PMID 10527675 DOI: 10.1006/mgme.1999.2896  0.52
1999 Watnick T, Germino GG. Molecular basis of autosomal dominant polycystic kidney disease. Seminars in Nephrology. 19: 327-43. PMID 10435671  0.52
1999 Pei Y, Watnick T, He N, Wang K, Liang Y, Parfrey P, Germino G, St George-Hyslop P. Somatic PKD2 mutations in individual kidney and liver cysts support a "two-hit" model of cystogenesis in type 2 autosomal dominant polycystic kidney disease. Journal of the American Society of Nephrology : Jasn. 10: 1524-9. PMID 10405208  0.52
1998 Watnick TJ, Torres VE, Gandolph MA, Qian F, Onuchic LF, Klinger KW, Landes G, Germino GG. Somatic mutation in individual liver cysts supports a two-hit model of cystogenesis in autosomal dominant polycystic kidney disease. Molecular Cell. 2: 247-51. PMID 9734362  0.52
1998 Watnick TJ, Gandolph MA, Weber H, Neumann HP, Germino GG. Gene conversion is a likely cause of mutation in PKD1. Human Molecular Genetics. 7: 1239-43. PMID 9668165  0.52
1997 Watnick TJ, Piontek KB, Cordal TM, Weber H, Gandolph MA, Qian F, Lens XM, Neumann HP, Germino GG. An unusual pattern of mutation in the duplicated portion of PKD1 is revealed by use of a novel strategy for mutation detection. Human Molecular Genetics. 6: 1473-81. PMID 9285784 DOI: 10.1093/hmg/6.9.1473  0.52
1997 Ibraghimov-Beskrovnaya O, Dackowski WR, Foggensteiner L, Coleman N, Thiru S, Petry LR, Burn TC, Connors TD, Van Raay T, Bradley J, Qian F, Onuchic LF, Watnick TJ, Piontek K, Hakim RM, et al. Polycystin: in vitro synthesis, in vivo tissue expression, and subcellular localization identifies a large membrane-associated protein. Proceedings of the National Academy of Sciences of the United States of America. 94: 6397-402. PMID 9177229 DOI: 10.1073/pnas.94.12.6397  0.52
1996 Qian F, Watnick TJ, Onuchic LF, Germino GG. The molecular basis of focal cyst formation in human autosomal dominant polycystic kidney disease type I. Cell. 87: 979-87. PMID 8978603 DOI: 10.1016/S0092-8674(00)81793-6  0.52
1995 Burn TC, Connors TD, Dackowski WR, Petry LR, Van Raay TJ, Millholland JM, Venet M, Miller G, Hakim RM, Landes GM, Klinger KW, Qian F, Onuchic LF, Watnick T, Germino GG, et al. Analysis of the genomic sequence for the autosomal dominant polycystic kidney disease (PKD1) gene predicts the presence of a leucine-rich repeat: The American PKD1 Consortium (APKD1 Consortium) Human Molecular Genetics. 4: 575-582. PMID 7633406 DOI: 10.1093/hmg/4.4.575  0.52
1988 Watnick TJ, Jenkins RR, Rackoff P, Baumgarten A, Bia MJ. Microalbuminuria and hypertension in long-term renal donors. Transplantation. 45: 59-65. PMID 3276064  0.52
Show low-probability matches.